检索结果-南通市图书馆

室内设计与装修 2024年第10期 50-54页

作者： chris Shao Studio chris Shao Studio 朱海工作室

黑天鹅法餐厅位于北京罗红摄影艺术馆一楼,面向好利来集团打造的东方园林艺术景观。优雅的现代曲线建筑被梦幻的东方山水围合,湖中天鹅游弋,怡然自得。这为餐厅的设计提供了基调与灵感——让现代主义的简约与自然山水相融,将天鹅视作灵... 详细信息

黑天鹅法餐厅位于北京罗红摄影艺术馆一楼,面向好利来集团打造的东方园林艺术景观。优雅的现代曲线建筑被梦幻的东方山水围合,湖中天鹅游弋,怡然自得。这为餐厅的设计提供了基调与灵感——让现代主义的简约与自然山水相融,将天鹅视作灵感缪斯。

关键词：艺术景观东方园林自然山水黑天鹅艺术馆餐厅曲线建筑围合

Evaluation of Phytochemical Contents and Antimicrobial Activities of Pandiaka heudelotii

在线全文

学校读者我要写书评

暂无评论

Advances in Biological Chemistry 2024年第2期14卷 55-63页

作者： Ikenna Obiora Alaekwe Uche Eunice Ekpunobi Vincent Ishmel Egbulefu Ajiwe Chinedu chris Aguoma Jamilu Ahmad Department of Chemistry Federal University Gusau Gusau Nigeria Department of Pure and Industrial Chemistry Nnamdi Azikiwe University Awka Awka Nigeria

The work investigated the secondary metabolites present in different parts of the Pandiaka heudelotii plant harvested from Ezira, Orumba south local government area of Anambra state, southeastern Nigeria as well as their antimicrobial activity. The objectives were to extract, determine the phytochemicals present, evaluate the antimicrobial potential and determine the zones of inhibition of the root, stem and leaf extracts of the plant. The emergence of antibiotics has decreased the spread and severity of a wide range of diseases. Plant extracts were tested for antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Streptococcus pyogenes, Bacillus subtelis, Pseudomonas aerogenes, Salmonella typhi, Aspergillus flavus, Aspergillus niger and Candida albicans. The zone of inhibition of extracts was compared with that of standard drugs like Erythromycin, Ciprofloxacin, Fulcin and Fluconazole. The result revealed the inhibition of bacterial and fungal growth with some test organisms. The microbial activity of the plant parts may be due to the presence of various secondary metabolites. The ethyl acetate extracts of Pandiaka heudelotii stood out with a minimum inhibitory concentration (MIC) range of 5 - 10 mg/mL and a minimum bactericidal concentration (MBC)/minimum fungicidal concentration (MFC) of 10 - 20 mg/ml against some test organisms. The plant can thus be worked upon to discover biologically active natural products that may serve as a prelude to the development of new pharmaceutical research undertakings.

关键词： Pharmaceuticals Secondary Metabolites Antibiotics Pandiaka heudelotii Bacteria

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

路易斯安那州历史博物馆美国巴吞鲁日

世界建筑导报 2024年第1期39卷 68-69页

作者：无 chris Rodriguez(摄影) EDR建筑事务所不详

这个博物馆位于路易斯安那州议会大厦,毗邻历史悠久的1932年国会大厦和花园,向游客展示了该州的全面历史。博物馆的选址与街对面的国家图书馆建立了双轴对称,沿着国会大厦总体规划的中央组织轴,它在塔的北部终止。博物馆可以从这两个方... 详细信息

这个博物馆位于路易斯安那州议会大厦,毗邻历史悠久的1932年国会大厦和花园,向游客展示了该州的全面历史。博物馆的选址与街对面的国家图书馆建立了双轴对称,沿着国会大厦总体规划的中央组织轴,它在塔的北部终止。博物馆可以从这两个方向中的任何一个方向进入,游客聚集在一个巨大的有顶棚的露台上,这是一种超大规模的“门廊”,向北开放,提供了国会大厦和花园的框架景观。

关键词：国家图书馆历史博物馆路易斯安那州超大规模总体规划

Subject-specific Finite Element Modelling of the Human Shoulder Complex Part 1:Model Construction and Quasi-static Abduction Simulation

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2020年第6期17卷 1224-1238页

作者： Manxu Zheng Zhihui Qian Zhenmin Zou chris Peach Mohammad Akrami Lei ren School of Mechanical Aerospace and Civil EngineeringUniversity of ManchesterManchesterM139PLUK Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong province School of Biomedical EngineeringSun Yat-sen UniversityGuangzhou 510006China Key Laboratory of Bionic Engineering Ministry of EducationJilin UniversityChangchun 130022China Shoulder and Elbow Unit The University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadWythenshaweManchester M239LTUK Department of Engineering College of EngineeringMathematicsand Physical SciencesUniversity of ExeterExeter EX44QFUK

Human shoulder joints exhibit stable but highly active characteristics due to a large amount of soft *** Element(FE)modelling plays an important role in enhancing our understanding of the mechanism of shoulder ***,the previous FE shoulder models largely neglected the Three-Dimensional(3D)volume of soft tissues and their sophisticated interactions with the *** study develops a 3D model of the rotator cuff and deltoid muscles and *** also includes cartilage and,for the first time,main ligaments around the joint to provide a better computational representation of the delicate interaction of the soft *** model has potential value for studying the force transfer mechanism and overall joint stability variation caused by 3D pathological changes of rotator cuff *** analysis systems and Magnetic Resonance(MR)scans were used to collect shoulder movement and geometric data from a young healthy subject,*** on MR images,a FE model with detailed representations of the musculoskeletal components was constructed.A multi-body model and the measured motion data were utilised to estimate the loading and boundary ***-static FE analyses simulated four instants of the measured scapular *** determined glenohumeral motion,stress/strain distribution in soft tissues,contact area,and mean/peak contact pressure were found to increase monotonically from 0°to 30°of *** results of muscle forces,bone-on-bone contact force,and superior-inferior movement of the humeral centre during motion were consistent with previous experimental and numerical *** is concluded that the constructed FE shoulder model can accurately estimate the biomechanics in the investigated range of motion and may be further used for the comprehensive study of shoulder musculoskeletal disorders.

关键词： shoulder complex biomechanics finite element glenohumeral joint subject-specific

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

领导为何不公?领导不公行为的形成机理

中国人力资源开发 2024年第1期41卷 112-124页

作者：陈思璇张春红段光卫旭华 chris M.Bell 南京理工大学经济管理学院南京210094 兰州大学管理学院兰州730000 湖南师范大学商学院长沙410081 约克大学舒立克商学院多伦多M3J1P3

领导不公行为是领导者违背公平准则的行为表现,对员工心理及行为的影响不容忽视。已有组织公平的研究广泛证实了领导不公行为对组织所造成的严重后果,但对领导不公行为的前因缺乏系统性的认知。为了全面系统地呈现领导不公行为形成的内... 详细信息

领导不公行为是领导者违背公平准则的行为表现,对员工心理及行为的影响不容忽视。已有组织公平的研究广泛证实了领导不公行为对组织所造成的严重后果,但对领导不公行为的前因缺乏系统性的认知。为了全面系统地呈现领导不公行为形成的内在逻辑,通过对相关文献的梳理,本文阐述了领导不公行为的内涵,对领导不公行为的相似构念进行了辨析,从道德正义理论、社会交换理论、态度功能理论、攻击性社会交互理论、自我损耗理论、自我概念维持理论的视角回顾了领导不公行为形成的理论解释,将领导不公行为归纳为不知而为的无意识不公以及知之而为的有意识不公两种基本模式。最后,从权威的视角切入,基于信息加工理论描述了领导者做出不公行为的信息加工过程,从自动化加工和系统化加工两方面详细讨论了领导不公行为的差异化形成机理,发展了一个形成机理模型。研究有助于推动领导不公行为的理论构建,为管理者做出有效的管理策略来减少领导不公行为提供实践启示。

关键词：领导不公行为信息加工理论组织公平

Vorolanib,an oral VEGFR/PDGFR dual tyrosine kinase inhibitor for treatment of patients with advanced solid tumors:An open-label,phaseⅠdose escalation and dose expansion trial

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer Research 2021年第1期33卷 103-114页

作者： Yan Song Jinwan wang Xiubao ren Jie Jin Li Mao chris Liang Lieming Ding Lin Yang Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Biotherapy Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Department of Urology Peking University First HospitalBeijing 100034China Betta Pharmaceuticals Co. Ltd.Hangzhou 311100China

Objective:This study evaluated the safety and preliminary efficacy of vorolanib,a novel tyrosine kinase inhibitor,for treatment of patients with advanced solid ***:During dose escalation,patients received increasing doses of oral vorolanib(50-250 mg once daily)in cycles of four weeks for up to one *** dose expansion,patients received recommended doses(100 and 200 mg)in 4-week *** primary endpoint was to determine the safety and maximum tolerated dose and/or the recommended phase II dose(RP2 D).The severity and type of adverse drug reactions(ADRs)were assessed using the Common Terminology Criteria for Adverse Events version *** second endpoint was preliminary efficacy in terms of objective response and progression-free survival(PFS).Results:No dose-limiting toxicity occurred during dose escalation(50-250 mg).Five(26.3%)patients in the escalation cohort(n=19)and 12(48.0%)in the expansion cohort(n=25)experienced grade 3 *** most common ADRs were hair color changes,fatigue,portal hypertension,hypertriglyceridemia,and *** dose expansion,the patients treated with 200 mg and 100 mg(once daily)showed an objective response rate of 22.2%and 5.9%,respectively;the disease control rate was 88.9%and 73.3%,respectively;the median PFS was9.9[95%confidence interval(95%CI):7.4-not reached]months and 3.8(95%CI:1.9-not reached)months,***:Oral vorolanib at a dose of 200 mg(once daily)exhibited an acceptable safety profile and favorable clinical benefit for patients with advanced solid *** RP2 D for vorolanib was determined to be 200 mg as a daily regimen.

关键词： Vorolanib TKI VEGFR PDGFR advanced solid tumor

在线全文

学校读者我要写书评

暂无评论

观看盗版,不减反增盗版网站流量大增

空中英语教室（高级版．彭蒙惠英语） 2024年第7期 6-7,38页

作者： chris Stokel-Walker 不详

网络盗版存在的时间几乎和互联网一样久,随着影音流媒体服务的数量与价格激增,使用盗版平台的潜在诱惑也随之增加。英国反盗版分析机构MUSO与科尔尼顾问管理公司的一份新分析展现了盗版的规模到底有多庞大。2023年,在线盗版网站的访问... 详细信息

网络盗版存在的时间几乎和互联网一样久,随着影音流媒体服务的数量与价格激增,使用盗版平台的潜在诱惑也随之增加。英国反盗版分析机构MUSO与科尔尼顾问管理公司的一份新分析展现了盗版的规模到底有多庞大。2023年,在线盗版网站的访问量高达1410亿次,相当于日访问量约3.86亿次。MUSO指出,这一数字自2019年以来增长了12%。

关键词：流媒体服务网站流量互联网访问量网络盗版反盗版科尔尼

典型结构功能一体化复合材料的设计与制备技术

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

复合材料学报 2024年第9期 4457-4477页

作者：蒋民强胡东源董晨昊 PIERCE Robert RUDD chris 刘晓玲益小苏宁波诺丁汉大学理工学院长三角碳纤维及复合材料技术创新中心丹麦技术大学风力与能源系统学院

在碳纤维增强树脂基复合材料轻量化与结构性能持续提高的前提下，同时附加其特定的功能，尤其是在不损失、甚至提升其层间断裂韧性的情况下，不仅可以弥补结构复合材料天然的缺陷，例如树脂基体的电绝缘性，也可以使其满足特定产品的要... 详细信息

在碳纤维增强树脂基复合材料轻量化与结构性能持续提高的前提下，同时附加其特定的功能，尤其是在不损失、甚至提升其层间断裂韧性的情况下，不仅可以弥补结构复合材料天然的缺陷，例如树脂基体的电绝缘性，也可以使其满足特定产品的要求，例如高刚度兼具一定的吸声降噪特性等。显然，对于航空航天这样的尖端应用领域，这种功能附加或结构功能一体化的复合材料技术对航空航天技术的未来发展至关重要。本文介绍了4种具有典型性的结构功能一体化复合材料的设计、制备与性能研究，分别是基于层间功能化插层和基于内织导电纬纱的导电增韧一体化复合材料及多级孔碳化棉纤维填充蜂窝/微穿孔面板的夹芯复合材料结构和编织布/无纺纤维毡复合材料片材折叠成型的结构吸声一体化复合材料。前两种材料分别通过在复合材料富树脂的层间插入导电功能化插层和在复合材料内引入贯通整个材料的导电纬纱网络实现了复合材料的导电性能与层间韧性的同步提高，而后两种材料则分别通过多级孔结构的碳化棉纤维材料填充蜂窝/微穿孔面板夹芯技术和编织布/无纺纤维毡复合材料片材的折叠技术实现了良好的吸声性能等，以展示多尺度、多层次结构设计和制备技术在结构复合材料功能化集成和结构功能一体化方面的应用。

关键词：碳纤维增强复合材料多功能复合材料导电增韧吸声

Refined chronology of prehistoric cultures and its implication for re-evaluating human-environment relations in the Hexi Corridor,northwest China

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2019年第10期62卷 1578-1590页

作者： Yishi YANG Shanjia ZHANG chris OLDKNOW Menghan QIU Tingting CHEN Haiming LI Yifu CUI Lele ren Guoke CHEN Hui wang Guanghui DONG Gansu Provincial Institute of Cultural Relics and Archaeology Lanzhou730000China MOE Key Laboratory of Western China抯Environmental Systems College of Earth&Environmental SciencesLanzhou UniversityLanzhou730000China History and Culture School Lanzhou UniversityLanzhou730000China CAS Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of Sciences(CAS)Beijing100101China

The reconstruction of high-resolution chronologies for prehistoric cultures is a prerequisite for understanding the history of human evolution and its relationship with environmental change, and is valuable for exploring the trajectory of transcontinental cultural exchanges in prehistoric time. The Hexi Corridor of northwest China was one of the earliest centers for long-distance culture exchange in the prehistoric world. The timing and sequence of cultural changes in this area remains poorly understood resulting from the lack of radiometric age control. This paper presents a refined radiocarbon(14 C) chronology to resolve the timing of human occupation and cultural evolution in the Hexi Corridor. Radiocarbon dating of crop remains, which have an annual life cycle, has the advantage of eliminating problems such as the carbon stored in ‘old wood’. As a result,14C dates from crop remains are used to test the validity of the14C dates derived from charcoal, bone and plant remains. The resultant database of ages is modelled using the Bayesian approach. The updated chronology presented in this paper shows generally good agreement with the original dates used to constrain cultural evolution in the Hexi Corridor. However, the occupation of the corridor by the Shajing and Shanma Late Bronze Age-Early Iron Age cultures appears to have taken place ~300 years later than previously thought. On the basis of comparing this updated chronology of cultural evolution with palaeoclimatic and historical records, it is proposed that the collapse of the Shajing and Shanma cultures occurred as a result of geopolitical impact rather than climate change.

关键词： Bayesian modelling Radiocarbon dating Neolithic and Bronze Age Chronology Geopolitical situation Climate change Hexi Corridor

在线全文

学校读者我要写书评

暂无评论

让年轻人重新加入欧盟英国首相犹豫不决

商业周刊（中文版） 2024年第14期 28-29页

作者： chris Bryant 杨飞(译) 不详

在英国脱欧问题上为年轻人做一点事情不仅是富有同情心的明智之举,而且是人心所向,如果基尔·斯塔默(Keir Starmer)在这个问题上仍然犹豫不决,那么工党在下院选举中赢得多数席位又有什么意义?在八月底访问柏林期间,这位工党首相重申,英... 详细信息

在英国脱欧问题上为年轻人做一点事情不仅是富有同情心的明智之举,而且是人心所向,如果基尔·斯塔默(Keir Starmer)在这个问题上仍然犹豫不决,那么工党在下院选举中赢得多数席位又有什么意义?在八月底访问柏林期间,这位工党首相重申,英国不打算加人“青年流动计划”。根据该计划,英国年轻人可以在欧盟生活、学习和工作几年,同时,来自欧洲大陆的30岁以下年轻人也能享受互惠安排。

关键词：斯塔英国首相工党明智之举英国脱欧同情心欧盟年轻人