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High-speed train positioning based on a combination of Beidou navigation, inertial navigation and an electronic map

Science China(Information Sciences) 2023年第7期66卷 237-252页

作者： Hui YANG Shuai-Qiang DONG chun-hua xie School of Electrical and Automation Engineering East China Jiaotong University Key Laboratory of Advanced Control & Optimization of Jiangxi Province East China Jiaotong University State Key Laboratory of Performance Monitoring Protecting of Rail Transit Infrastructure East China Jiaotong University

To date, the studies on the combination positioning of high-speed trains have made great progress, but the positioning accuracy of these methods is relatively low. Map-matching positioning can improve positioning accuracy, but information transmission is time-consuming. Few studies incorporate it into combination positioning. To solve the problem, this paper proposes a high-speed train positioning method based on combining a Beidou navigation system, an inertial navigation system, and an electronic map. First, the combination positioning problem is transformed into a multi-objective optimization problem, which weights the direction similarity and distance error to form a fitness function and converts the railway line and the maximum error range of each positioning system into constraints. Second, an improved differential evolution algorithm is proposed to solve this problem. By referencing the gray wolf algorithm,the differential evolution algorithm updates individuals by varying toward the direction of multiple optimal values. Then, a new combination positioning algorithm for high-speed trains is proposed. In the simulation,the increase in positioning speed and accuracy is analyzed and validated. Compared to the current algorithms, the proposed algorithm performs better. The proposed method has practical value for improving the reliability and safety of train operations.

关键词： electronic map multi-objective optimization differential evolution algorithm Beidou navigation system high-speed train positioning

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Asymptotic state estimation for linear systems with sensor and actuator faults

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Science China(Information Sciences) 2019年第11期62卷 106-120页

作者： chun-hua xie Hui YANG Dianhui WANG Zhe LI School of Electrical and Automation Engineering East China Jiaotong University Key Laboratory of Advanced Control & Optimization of Jiangxi Province Department of Computer Science and Information Technology La Trobe University College of Electrical and Information Engineering Hunan University

This paper investigates the asymptotic state estimation problem for linear systems with sensor and actuator faults, where the faults are modeled via multiple modes. For the case of sensor faults, we first introduce a new notion of detectability, i.e., detectability of system against sensor faults. The notion helps to address the question of whether it is possible to asymptotically estimate the system state by using the control input and system output, irrespective of which mode the system is in and what values the fault signals are.A necessary and sufficient condition for the system to be detectable against sensor faults is given, and then two switched observers are proposed for asymptotic state estimation with the help of maximin strategy. For the system with ? fault modes, we provide the explicit form of the switched observer, which is based on a bank of ?(?+1)/2 Luenberger-like or sliding-mode observers. Furthermore, extensions to the case of sensor and actuator faults are further studied. Finally, a simulation example of a reduced-order aircraft system is provided to show the effectiveness of the proposed approaches.

关键词： asymptotic state estimation observer linear systems sensor faults actuator faults

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Static-feedback guaranteed cost control for linear systems with outage and loss of effectiveness actuator faults

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Journal of Control and Decision 2022年第4期9卷 407-419页

作者： chun-hua xie Zhe Li Yanli Zhou School of Electrical and Automation Engineering East China Jiaotong UniversityNanchangPeople’s Republic of China Key Laboratory of Advanced Control&Optimization of Jiangxi Province NanchangPeople’s Republic of China cCollege of Electrical and Information Engineering Hunan UniversityChangshaPeople’s Republic of China

This paper investigates the static-feedback guaranteed cost control problem for linear systems with actuator faults including outage and loss of *** the actuator redundancy condition,theoretical analysis shows that a static-feedback guaranteed cost controller can always be well designed to ensure that the resulting closed-loop system is stable with desirable quadratic *** particular,the feedback gain can be determined through the solution of a modified algebraic Riccati ***,extension to the system with uncertainties is further *** with the dynamic feedback controller,the static-feedback controller consists only of logical gates/modules and it does not require any memory element,and hence it is simplest in a design *** from the existing results,the severe and timevarying actuator outage faults can be handled very well by the proposed control ***,simulation on a linearised reduced-order aircraft system is provided for verifying the theoretical results.

关键词： Static-feedback guaranteed cost control linear systems actuator outage faults algebraic Riccati equation

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稀疏恶意攻击下的信息物理系统的“PID”型性能和安全控制

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中国科学：信息科学 2021年第1期51卷 89-103页

作者：谢春华杨辉李哲华东交通大学电气与自动化工程学院南昌330013 江西省先进控制与优化重点实验室南昌330013 湖南大学电气与信息工程学院长沙410082

针对遭受稀疏恶意攻击的离散时间线性系统,本文研究其安全控制问题.假设恶意攻击者受有限资源的约束,仅能操控远程控制器和执行器之间的若干通信通道.对于设计者来说,并不知道哪些通道受到攻击,哪些通道没有受到攻击.本文提出了一种新... 详细信息

针对遭受稀疏恶意攻击的离散时间线性系统,本文研究其安全控制问题.假设恶意攻击者受有限资源的约束,仅能操控远程控制器和执行器之间的若干通信通道.对于设计者来说,并不知道哪些通道受到攻击,哪些通道没有受到攻击.本文提出了一种新的安全的远程控制方法,它由控制律、切换函数和选择机制构成.选择机制为控制律提供合适的反馈增益,并产生一个切换函数,用以阻止攻击信号进入被控对象.理论分析表明,在基本的和必要的假设条件下,本文考虑的安全控制问题可转化为求解状态反馈镇定问题.本文所提控制方法,能保证闭环系统的稳定性且使其具有"PID"型性能的抗攻击能力.最后,通过对某无人地面车辆系统的仿真实验,验证了理论结果的正确性.

关键词：安全控制信息物理系统稀疏恶意攻击切换策略抗攻击性能

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Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

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Traditional Medicine Research 2025年第2期10卷 55-64页

作者： Jin-Fang Wu Yi-Sheng Chen Yu-chun xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity

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Hutchinson-Gilford Progeria Syndrome and its Relevance to Cardiovascular Diseases and Normal Aging

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Biomedical and Environmental Sciences 2013年第5期26卷 382-389页

作者： QI Ying chun xie Xiao hua First Department of Comprehensive Surgery in South Building Chinese PLA General Hospital

Hutchinson-Gilford progeria syndrome(HGPS,OMIM176670)is an extremely rare,sporadic genetic syndrome with a reported prevalence of one in4-8million children *** April2012,the total number of known living children with ... 详细信息

关键词： HGPS Hutchinson-Gilford Progeria Syndrome and its Relevance to Cardiovascular Diseases and Normal Aging

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流沙湾养殖结构优化与生态环境生物修复技术

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水产学报 2010年第7期34卷 1051-1061页

作者：申玉春陈文霞朱春华叶宁谢恩义梁飞龙杜晓东吴灶和广东省南海水产经济动物增养殖重点实验室广东海洋大学

建立了一种贝-鱼-藻养殖结构优化与生态环境生物修复系统,该系统通过网栏设置33.3hm2半封闭的养殖海区进行试验研究,在示范海区内设置3个功能不同的养殖区,贝类养殖与珍珠培育区、鱼类网箱养殖区、大型海藻栽培区,进行鱼类与大型海藻间... 详细信息

建立了一种贝-鱼-藻养殖结构优化与生态环境生物修复系统,该系统通过网栏设置33.3hm2半封闭的养殖海区进行试验研究,在示范海区内设置3个功能不同的养殖区,贝类养殖与珍珠培育区、鱼类网箱养殖区、大型海藻栽培区,进行鱼类与大型海藻间养和珍珠培育。经过10个月的结构优化养殖和生态环境生物修复控制,示范海区水域水质和生物环境得以明显改善。示范海区透明度显著高于毗邻海区(P<0.05),悬浮物含量显著低于毗邻海区(P<0.05);示范海区总氮、总磷营养盐浓度随养殖期的延长逐渐升高,到9月份达到最高值,以后则逐渐下降;示范海区水域浮游生物数量随养殖时间的延长逐渐升高,浮游生物量明显高于毗邻海区(P<0.05)。示范海区养殖生物生长良好,共收获鱼类21365kg、大型海藻3091.3kg、珍珠33.5kg。育珠贝存活率为73.9%、育珠贝留核率为49.9%,优质珠比率13.7%、珠层厚度平均472μm,珍珠质量明显提高。示范海区光能利用率为0.20%,总能量转化效率为34.58%,单位净产量耗总能为2.8919MJ/kg。

关键词：养殖结构生态环境生物修复流沙湾

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Stochastic Resonance in a Bistable System Subject to Non-Gaussian and Gaussian Noises

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Communications in Theoretical Physics 2008年第11期50卷 1165-1168页

作者： ZENG chun-hua CHEN Li-Li xie Chong-Wei Department of Physics Yunnan University Kunming 650091 China Faculty of Continuing Education Kunming University of Science and Technology Kunming 650093 China

In this paper, we consider the phenomenon of stochastic resonance （SR） in a quartic bistable system under the simultaneous action of a multiplicative non-Gaussian and an additive Gaussian noises and a weak periodic signal. The expression of the signal-to-noise ratio R is derived by applying the two-state theory in adiabatic limit. We discuss the effects of the parameter q indicating the departure of the non-Gaussian noise from the Gaussian noise, the correlation time r of the non-Gaussian noise, and coupling intensity A between two noise terms on the stochastic resonance. It is found that the signM-to-noise ratio of the system, as a function of the additive noise intensity, undergoes the transition from having one peak to having two peaks, and then to having one peak again when the parameter q or the noise correlation time τ is increased. The parameter q and τ play opposite roles in the SR of the system.

关键词： stochastic resonance non-Gaussian noise

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Homopolypeptide Vesicles Triggered by Side-Chain Hydration

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Chinese Journal of Polymer Science 2022年第12期40卷 1631-1639,I0009页

作者： Xin-Jie Shi Zhen Liu Yang-chun xie Min Xu Xiao-hua He School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241China School of Physics and Electronic Science Shanghai Key Laboratory of Magnetic ResonanceEast China Normal UniversityShanghai 200241China

The formation of homopolypeptide vesicles and the identification of their self-assembly mechanism have been challenging issues in the field of polymer self-assembly. Using complementary circular dichroism(CD), Fourier transform infrared(FTIR) and low-field nuclear magnetic resonance(LF-NMR) spectroscopies, in this study we show that the higher hydrophilic ability of side-chains is a key factor for the formation of homopolypeptide vesicles from homo poly(Nε-carbobenzoxy-L-lysine)(PZlys), in which the vesicular structures are confirmed by scanning electron microscopy(SEM), transmission electron microscopy(TEM) and atomic force microscopy(AFM) measurements. Poly(γ-benzyl-Lglutamate-co-Nε-carbobenzoxy-L-lysine) [P(BLG-co-Zlys)] containing different molar ratios of BLG to Zlys units with the same peptide backbone as PZlys are used as the controls. The copolypeptides can only form micelles under the same conditions, due to the more hydrophobic nature of their side-chains. These results show that the specific side-chain structure of the polypeptides plays a fundamental role in the self-assembly of homopolypeptides. These findings can be useful to understand how the hydrophilicity of the side chains of amino acid residues on the surface of a protein affects its structures.

关键词： Polypeptide Vesicle Self-assembly Hydrophobic Micelle

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Stem cell-based therapies for fertility preservation in males:Current status and future prospects

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World Journal of Stem Cells 2020年第10期12卷 1097-1112页

作者： Han-Chao Liu Yun xie chun-hua Deng Gui-hua Liu Department of Andrology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina Reproductive Medicine Research Center The Sixth Affiliated Hospital of Sun Yatsen UniversityGuangzhou 510655Guangdong ProvinceChina

With the decline in male fertility in recent years,strategies for male fertility preservation have received increasing *** this study,by reviewing current treatments and recent publications,we describe research progress in and the future directions of stem cell-based therapies for male fertility preservation,focusing on the use of spermatogonial stem cells(SSCs),SSC niches,SSC-based testicular organoids,other stem cell types such as mesenchymal stem cells,and stem cell-derived extracellular *** conclusion,a more comprehensive understanding of the germ cell microenvironment,stem cell-derived extracellular vesicles,and testicular organoids will play an important role in achieving male fertility preservation.

关键词： Fertility preservation Sperm cryopreservation Spermatogonial stem cell Testicular organoids Stem cell Extracellular vesicles

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