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Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： HUANG Hao-yue liN Yu-ping WEI Hua FU Yu ZHOU Yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei li Qing-bo li Shan-shan WANG Shi-dong DAI Fang liU Zhen-jie ZHAO ling WEN Jian-xuan WU li-yan zeng Hui-yan ZHANG Jin-ming LU Qi-yun HE liu SONG Wei SUN Lu LUO Lu-lu HE Jia-li XIE Wen-wen liANG Qing-shun HUANG Yuan ZHU Sheng-ling long Jie-er GAO Zhi-juan WEN Ze-huai li chun-ji OUYANG Wen-wei li Geng WU Ming-hui li An-xiang HUANG Jin-zhu Sanjoy K Paul tang Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial tangbi Waixi Decoction

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针刺治疗功能性便秘的机制研究进展

针刺研究 2024年第1期49卷 79-87页

作者：李艳秋姚俊鹏鄢香芸杨婉卿陈敏唐太春李瑛成都中医药大学针灸推拿学院成都610075 成都中医药大学附属医院成都610075

针刺治疗功能性便秘(FC)疗效确切,具有早期起效迅速、远期疗效稳定和整体性调节的特点。本文检索并总结近年来针刺治疗FC的相关文献,结果显示针刺能从促进肠道动力、调节肠道菌群、调节脑-肠轴、减轻肠道炎性反应、改善直肠低敏感性等... 详细信息

针刺治疗功能性便秘(FC)疗效确切,具有早期起效迅速、远期疗效稳定和整体性调节的特点。本文检索并总结近年来针刺治疗FC的相关文献,结果显示针刺能从促进肠道动力、调节肠道菌群、调节脑-肠轴、减轻肠道炎性反应、改善直肠低敏感性等多角度、多途径发挥作用。未来研究可深入挖掘针刺改善直肠低敏感性的机械传感机制、明确针刺调控的关键肠道菌属及代谢特征、探究不同作用机制间的网络关系,并阐明不同针刺治疗方案的效应差异机制,以期更好地优化临床治疗方案,提高针刺治疗FC的临床疗效。

关键词：功能性便秘针刺机制综述

某高压长距离变径铁精矿矿浆管道清管除垢实践

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包钢科技 2024年第1期50卷 10-14页

作者：唐林匙胜利卫强周春林李扬曾辉宋士祥中油管道检测技术有限责任公司河北廊坊065000

文章以某长距离高压变径铁精矿矿浆管道清管除垢为例,系统介绍了矿浆管道的杂质分布特征以及不同类型清管器的清管效果。通过实际清管发现,采用软质泡沫清管器和不同邵氏硬度皮碗的机械清管器可初步探测出管道的可通过性。另外,泡沫清... 详细信息

文章以某长距离高压变径铁精矿矿浆管道清管除垢为例,系统介绍了矿浆管道的杂质分布特征以及不同类型清管器的清管效果。通过实际清管发现,采用软质泡沫清管器和不同邵氏硬度皮碗的机械清管器可初步探测出管道的可通过性。另外,泡沫清管器对矿浆管道的结垢物清理效果较差,应优先采用清管能力更强的机械清管器,这对今后类似矿浆管道的清管具有重要的指导意义。

关键词：矿浆管道高压管道变径管道清管除垢

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微波催化面粉发酵效应研究

真空电子技术 2024年第2期 52-55页

作者：傅文杰柳建龙唐相伟刘奇郑弘佑周福昌黎晓云曾葆青电子科技大学电子科学与工程学院太赫兹科学技术四川省重点实验室四川成都611731 电子科技大学美的微波管技术与微波能应用联合实验室四川成都611731 广东美的厨房电器制造有限公司创新中心广东佛山528311

面粉发酵食品是一种重要的食品类型,但传统的自然面粉发酵需较长的时间,而微波场的激励下,有望增强发酵过程中的催化活性,进而促进反应速率,缩短反应时间。本文对微波催化发酵面粉效应进行了实验研究,通过优化实验参数,成功缩短了发酵时... 详细信息

面粉发酵食品是一种重要的食品类型,但传统的自然面粉发酵需较长的时间,而微波场的激励下,有望增强发酵过程中的催化活性,进而促进反应速率,缩短反应时间。本文对微波催化发酵面粉效应进行了实验研究,通过优化实验参数,成功缩短了发酵时间,并且耗能极低。测试结果表明微波催化发酵面粉与自然发酵面粉的组分基本相同。

关键词：微波催化面粉发酵

Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus during pregnancy response to sorafenib

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Chinese Medical Journal 2010年第15期123卷 2155-2158页

作者： WU yun-jian ZHU Yu-chun CHEN Hui HUANG Ying WEI Qiang CHEN Hui-jiao XIE Xi li xiang ZHOU Qiao YANG Yu-ru zeng Hao Department of Urology West China Hospital Sichuan UniversityChengdu Sichuan 610041 China Department of Gynaecology and Obstetrics Second Affiliated West China Hospital Sichuan University Chengdu Sichuan 610041 China Department of Pathology West China Hospital Sichuan UniversityChengdu Sichuan 610041 China

Primitive neuroectodermal tumor （PNET） most often presents as a bone or soft tissue mass in the trunk or axial skeleton in adolescents and young adults.1 It is highly aggressive and rarely arises in the kidney.2 A combined therapy, consisting of surgical resection,chemotherapy and radiotherapy, is needed to treat this tumor but long-term survival remains poor.3,4 In the current study, we describe a case of 26-year-old woman （primigravida） who presented with a PNET of the right kidney with inferior vena cava （IVC） tumor thrombus.

关键词： primitive neuroectodermal tumor kidney pregnancy thrombus sorafenib

Prolonged parasite clearance in a Chinese splenectomized patient with falciparum malaria imported from Nigeria

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Infectious Diseases of Poverty 2017年第1期6卷 395-400页

作者： Hong-Wei Zhang San-Jin li Tao Hu Yong-Min Yu Cheng-yun Yang Rui-Min Zhou Ying liu Jing tang Jing-Jing Wang Xiu-yun Wang Yong-xiang Sun Zhan-chun Feng Bian-li Xu Department of Parasite Disease Control and Prevention Henan Center for Disease Control and PreventionZhengzhouPeople’s Republic of China Department of Infectious Diseases the 6th People’s Hospital of ZhengzhouZhengzhou 450016People’s Republic of China School of Medicine and Health Management Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030HubeiPeople’s Republic of China

Background:The spleen plays a pivotal role in the rapid clearance of parasitized red blood cells in patients with falciparum malaria after artemisinin *** parasite clearance can be found in patients who have had a splenectomy,or those with hemoglobin abnormalities and/or reduced immunity,which are all distinguishable from artemisinin *** paper reports on a case of prolonged parasite clearance in a Chinese splenectomized patient with falciparum malaria imported from *** presentation:A 35-year-old Chinese male suffered 2 days of febrile illness after returning to Zhumadian city of Henan province from Nigeria on October 1,*** main symptoms were febrile,including the highest axillary temperature of 40℃,headache,and chills.A peripheral blood smear showed parasitemia(53913 asexual parasites/μl)of Plasmodium *** patient had not used any chemoprophylaxis against malaria in Nigeria when he worked there as a construction worker between 2009 and *** patient had three episodes of malaria in Nigeria and had a splenectomy due to a traffic accident 8 years ago from the time he was admitted to *** patient was orally administrated a total of 320 mg/2.56 g dihydroartemisinin-piperaquine for 2 days and intravenously administrated a total of 3000 mg artesunate for 18 *** axillary temperature of the patient ranged between 37.0 and 37.7℃ from Day 0 to Day 3,and blood microscopy revealed falciparum malaria parasitemia(26674 asexual parasites/μl)on Day *** patient was afebrile on Day 4,falciparum malaria parasitemia was continuously present and then gradually decreased on the next days,and was negative on Day *** patient was cured and left hospital on Day 24 after no plasmodium falciparum was found in the blood on Day 21 to Day *** mutation was found in the K13 propeller gene when compared with the PF3D7_1343700 K13 propeller gene reference ***:This is the first reported case in China of prolong

关键词： Falciparum malaria Artemisinin treatment Prolonged parasite clearance Splenectomy China Nigeria

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长寿命高选择性液膜碘离子电极的研究

高等学校化学学报 1999年第4期20卷 603-607页

作者：曾云龙唐春然沈国励俞汝勤邵阳师范高等专科学校化学系湖南大学化学化工学院

合成了ＰＶＣ－双硫腙－Ｈｇ（Ⅱ）载体．以该载体物质制备了高选择性碘离子电极，其选择性次序为：Ｉ－ＣｌＯ－４＞ＳＣＮ－＞ＮＯ－２Ｓａｌ－～Ｂｒ－＞ＮＯ－３＞Ｃｌ－．电极对碘离子的线性响应范围为１×１０－３～５×１０... 详细信息

合成了ＰＶＣ－双硫腙－Ｈｇ（Ⅱ）载体．以该载体物质制备了高选择性碘离子电极，其选择性次序为：Ｉ－ＣｌＯ－４＞ＳＣＮ－＞ＮＯ－２Ｓａｌ－～Ｂｒ－＞ＮＯ－３＞Ｃｌ－．电极对碘离子的线性响应范围为１×１０－３～５×１０－７ｍｏｌ／Ｌ，检测下限为２×１０－７ｍｏｌ／Ｌ，斜率为（５９±１）ｍＶ／ｄｅｃａｄｅ（１６℃）．并研究了电极的响应机理，表明系碘离子与载体中金属汞原子直接作用．将该电极应用于食盐中碘的测定。

关键词：液膜离子选择性电极碘离子电极测定

合成N,N,N',N'-四(2-甲酯基乙基)乙二胺的绿色工艺研究

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湖南科技大学学报（自然科学版） 2006年第3期21卷 81-84页

作者：黄玉芳曾云龙唐春然李春香吴湘江湖南科技大学化学化工学院湖南湘潭411201

为了解决合成聚酰胺-胺时回收液处理复杂、能耗大、并污染环境的问题,以合成N,N,N',N'-四(2-甲酯基乙基)乙二胺(TMCEDA)为研究对象,对不同真空度条件下的回收液进行了定性定量分析,在此基础上,采用分段减压蒸馏分离合成TM-CEDA中的过量... 详细信息

为了解决合成聚酰胺-胺时回收液处理复杂、能耗大、并污染环境的问题,以合成N,N,N',N'-四(2-甲酯基乙基)乙二胺(TMCEDA)为研究对象,对不同真空度条件下的回收液进行了定性定量分析,在此基础上,采用分段减压蒸馏分离合成TM-CEDA中的过量原料与溶剂,直接循环使用真空度在50kPa-100kPa的回收液的新工艺.应用气相色谱分析技术跟踪分析循环使用的回收液的成分,结果表明,经过40次循环使用的回收液,仍未见明显的杂质积累现象.该工艺对回收液的直接使用率高达98.0%,实现了TMCEDA的实验室绿色合成,可为其工业化生产提供参考.图7,表2,参11.

关键词： N,N,N′,N′-四(2-甲酯基乙基)乙二胺回收液分段减压蒸馏直接循环使用节能降耗

水稻OsGMS2基因的鉴定及其核不育系种子繁殖体系构建

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作物学报 2023年第8期49卷 2025-2038页

作者：唐杰龙湍吴春瑜李新鹏曾翔吴永忠黄培劲海南波莲科技有限公司海南海口570125 海南大学热带作物学院海南海口570208

雄性不育是作物杂种优势利用的基础。本研究在籼稻93-1160Co-γ辐射诱变突变体库中鉴定了一个普通核雄性不育突变体osgms2。突变体雄性彻底败育,雌性育性正常,其他农艺性状与野生型一致。遗传分析表明雄性不育稳定遗传且为单基因隐性突... 详细信息

雄性不育是作物杂种优势利用的基础。本研究在籼稻93-1160Co-γ辐射诱变突变体库中鉴定了一个普通核雄性不育突变体osgms2。突变体雄性彻底败育,雌性育性正常,其他农艺性状与野生型一致。遗传分析表明雄性不育稳定遗传且为单基因隐性突变,通过与明恢63构建遗传群体将突变基因精细定位于水稻4号染色体长臂的分子标记S3b和4826之间86kb物理区间内。通过测序分析发现定位区间内一编码类成束阿拉伯半乳聚糖蛋白的基因LOC_Os04g48490编码区第118位至126位缺失连续9个碱基,导致氨基酸整码突变。OsGMS2与已报道的OsFLA1为同一基因,但是突变位点不同的新等位突变。粳稻中花11背景下的基因敲除和遗传互补实验证实了该基因的功能。实时荧光定量PCR(qPCR)表达分析模式显示,该基因在水稻各组织均有表达,但在花期和乳熟期种子表达量较高。蛋白同源比对分析发现,该蛋白序列保守,可能在不同物种中发挥重要功能。通过创建OsGMS2-T保持系成功实现了普通核不育系的繁殖。osgms2突变体的发现和基因鉴定为水稻普通核雄性不育研究及杂种优势利用提供了新的材料。

关键词：水稻核雄性不育 osgms2 基因定位 OsGMS2-T保持系

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