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Gastroenterology Report 2019年第5期7卷 376-377,I0003页

作者： Hyun ho choi Mong-hong Lee Guangdong Research Institute of Gastroenterology The Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina

Many microorganisms reside in the gastrointestinal tract and the dysbiosis of microorganisms can affect our *** have a relatively low level of presence(about 0.1%of the totalmicroorganisms)compared with bacteria,which makes it easier to underestimate their potential threat to ***,fungal infections indeed participate in the onset and progression of many intestinal diseases,so they are crucially affecting our health[1,2].Recently,Li et *** that C-type lectin receptors(CLRs)on myeloid cells,including Dectin-1,Dectin-2,Dectin-3,and Mincle,play an important role in the immune function induced by fungal pathogens of the intestinal microbiota[3].

关键词： C型凝集素受体胃肠道疾病真菌感染

Targeting host-microbe interaction in mucus layer:a potential treatment option for diseases

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Gastroenterology Report 2019年第1期7卷 1-2,I0001页

作者： Hyun ho choi Mong-hong Lee Guangdong Research Institute of Gastroenterology The Sixth Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouGuangdongP.R.China

Human gut microbiota,containing at least 100 trillion bacteria,resides in the mucosal surface of the human *** individual is host to a distinct set of at least 160 species in the *** collective microbial genome encodes 500 times more genes than the human genome,and so it is tempting to consider human genes as noise in the storm of microbial signals[1].Recent data suggest that,while microbial signals modulate crucial functions of the healthy human body,there are also accumulating data suggesting that many human diseases have their origin in distorted gut microbiota composition[2].

关键词： intestine 疾病治疗黏液层

Single-port laparoscopic surgery for sigmoid volvulus

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World Journal of Gastroenterology 2015年第8期21卷 2381-2386页

作者： Byung Jo choi Won Jun Jeong Say-June Kim Sang chul Lee Department of Surgery Daejeon St. Mary’s Hospital College of Medicine The Catholic University of Korea

AIM:To report our experience with single-port laparoscopic surgery(SPLS)for sigmoid volvulus(SV).METhoDS:Between October 2009 and April 2013,10patients underwent SPLS for *** was performed transumbilically or through a predetermined stoma *** straight and rigid-type laparoscopic instruments were *** intracorporeal,segmental resection of the affected sigmoid colon,the specimen was extracted through the single-incision *** and perioperative data were ***:SPLS for SV was successful in all 10 patients(4,resection and primary anastomosis;6,Hartmann’s procedure).The median operative time and postoperative hospitalization period were 168(range,85-315)min and 6.5(range,4-29)d,*** intraoperative complications were noted;there were 2 postoperative complications,including 1 anastomotic ***:SPLS was a safe and feasible therapeutic approach for SV,when performed by a surgeon experienced in conventional laparoscopic surgery.

关键词： Sigmoid volvulus Laparoscopy Single-port Anastomos

Circulation and its seasonal variability in region around the Kerguelen Plateau

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Acta Oceanologica Sinica 2002年第1期21卷 1-17页

作者：史久新乐肯堂 Byung ho choi Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 ChinaFirst Institute of Oceanography State Oceanic Administration Qingdao 266061 China Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China Sung Kyun Kwan University Suwon 440- 746 Korea

A coupled ice-ocean isopycnal numerical model of the Southern Ocean is established tostudy the circulation and its seasonal variability in the region around the Kerguelen Plateau. An analysis of the simulated results shows significant stripe-like structure and non-zonal feature of the Antarctic Cir-cumpolar Current (ACC) in this region. ACC begins to bifurcate and to turn its direction before meeting the plateau. The southernmost branch of ACC is near to the Antarctic coast and displays its strong interaction with the westward Antarctic Slope Current. The northern branch of ACC has a tendency of annual variations while the southern one varies in a semiannual cycle. The variation phases of both branches are coincident with that of the wind stress in this region.

关键词： Circulation seasonal variability the Southern Ocean

Generation of induced secretome from adipose-derived stem cells specialized for disease-specific treatment:An experimental mouse model

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World Journal of Stem Cells 2020年第1期12卷 70-86页

作者： Ok-Hee Kim Ha-Eun hong Haeyeon Seo Bong Jun Kwak ho Joong choi Kee-Hwan Kim Joseph Ahn Sang chul Lee Say-June Kim Catholic Central Laboratory of Surgery Institute of Biomedical IndustryCollege of Medicinethe Catholic University of KoreaSeoul 06591South Korea Department of Surgery Division of Hepato-biliary Pancreatic SurgerySeoul St.Mary’s HospitalCollege of Medicinethe Catholic University of KoreaSeoul 06591South Korea Department of Surgery Uijeongbu St.Mary's HospitalCollege of Medicinethe Catholic University of KoreaSeoul 11765South Korea Department of Surgery Daejeon St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 34943South Korea

BACKGROUND Recently,the exclusive use of mesenchymal stem cell(MSC)-secreted molecules,named as the secretome,have been evaluated for overcoming the limitations of cell-based therapy while maintaining its *** To improve cell-free therapy by adding disease-specificity through stimulation of MSCs using disease-causing *** We collected the secretory materials(named as inducers)released from AML12 hepatocytes that had been pretreated with thioacetamide(TAA)and generated the TAA-induced secretome(TAA-isecretome)after stimulating adipose-derived stem cells with the *** TAA-isecretome was intravenously administered to mice with TAA-induced hepatic failure and those with partial *** TAA-isecretome infusion showed higher therapeutic potential in terms of(1)restoring disorganized hepatic tissue to normal tissue;(2)inhibiting proinflammatory cytokines(interleukin-6 and tumor necrosis factor-α);and(3)reducing abnormally elevated liver enzymes(aspartate aminotransferase and alanine aminotransferase)compared to the naïve secretome infusion in mice with TAA-induced hepatic ***,the TAA-isecretome showed inferior therapeutic potential for restoring hepatic function in partially hepatectomized *** analysis of TAA-isecretome identified that antioxidant processes were the most predominant enriched biological networks of the proteins exclusively identified in the *** addition,peroxiredoxin-1,a potent antioxidant protein,was found to be one of representative components of TAA-isecretome and played a central role in the protection of TAA-induced hepatic *** Appropriate stimulation of adipose-derived stem cells with TAA led to the production of a secretome enriched with proteins,especially peroxiredoxin-1,with higher antioxidant *** results suggest that appropriate stimulation of MSCs with pathogenic agents can lead to the production of a secretome specialized for protecting agains

关键词： Adipose-derived stem cells Disease-specificity Mesenchymal stem cells Secretome Peroxiredoxin-1 Thioacetamide Toxic hepatic failure

Robotic cholecystectomy with new port sites

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World Journal of Gastroenterology 2013年第20期19卷 3077-3082页

作者： Ji Hun Kim Nam Hyun Baek Guangyl Li Seung Hui choi In ho Jeong Jae chul Hwang Jin hong Kim Byung Moo Yoo Wook Hwan Kim Departments of Surgery School of MedicineAjou UniversitySuwon 442-749South Korea Departments of Gastroenterology School of MedicineAjou UniversitySuwon 442-749South Korea

AIM:To introduce robotic cholecystectomy(RC) using new port sites on the low abdominal ***:From June 2010 to June 2011,a total of 178 RCs were performed at Ajou University Medical *** prospectively collected the set-up time(working time and docking time) and console time in all robotic ***:Eighty-three patients were male and 95 female;the age ranged from 18 to 72 years of age(mean 54.6 ± 15.0 years).All robotic procedures were successfully *** mean operation time was 52.4 ± 17.1 *** set-up time and console time were 11.9 ± 5.4 min(5-43 min) and 15.1 ± 8.0 min(4-50 min),*** conversion rate to laparoscopic or open procedures was *** complication rate was 0.6%(n = 1,bleeding).There was no bile duct injury or *** mean hospital stay was 1.4 ± 1.1 *** was a significant correlation between the console time and white blood cell count(r = 0.033,P = 0.015).In addition,the higher the white blood cell count(more than 10000),the longer the console ***:Robotic cholecystectomy using new port sites on the low abdominal area can be safely and efficiently performed,with sufficient patient satisfaction.

关键词： Robotic cholecystectomy Port sites Operation time Abdominal area Gallbladder disease

Retrieval of Outgoing Longwave Radiation from COMS Narrowband Infrared Imagery

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Advances in Atmospheric Sciences 2015年第3期32卷 375-388页

作者： Myung-Sook PARK Chang-hoi ho Heeje Cho Yong-Sang choi School of Earth and Environmental Sciences Seoul National UniversitySeoul Korea School of Urban and Environmental Engineering Ulsan National Institute of Science & TechnologyUlsan Korea Computational Science and Technology Seoul National UniversitySeoul Korea Computational Science and Technology Seoul National UniversitySeoul Korea Department of Environmental Science and Engineering Ewha Womans UniversitySeoul Korea

hourly outgoing longwave radiation （OLR） from the geostationary satellite Communication Oceanography Meteorological Satellite （COMS） has been retrieved since June *** COMS OLR retrieval algorithms are based on regression analyses of radiative transfer simulations for spectral functions of COMS infrared *** study documents the accuracies of OLRs for future climate applications by making an intercomparison of four OLRs from one single-channel algorithm （OLR12.0 using the 12.0 μm channel） and three multiple-channel algorithms （OLR10.8＋12.0 using the 10.8 and 12.0 pm channels; OLR6.7＋10.8 using the 6.7 and 10.8 μm channels; and OLRAll using the 6.7,10.8,and 12.0 μm channels）.The COMS OLRs from these algorithms were validated with direct measurements of OLR from a broadband radiometer of the Clouds and Earth＇s Radiant Energy System （CERES） over the full COMS field of view [roughly （50°S-50°N,70°-170°E）] during April *** results show that the root-mean-square errors of COMS OLRs are 5-7 W m-2,which indicates good agreement with CERES OLR over the vast ***6.7＋10.8 and OLRAll have much smaller errors （～ 6 W m-2） than OLR12.0 and OLR10.8＋12.0 （～ 8 W m-2）.Moreover,the small errors of OLR6.7＋10.8 and OLRAll are systematic and can be readily reduced through additional mean bias correction and/or radiance *** results indicate a noteworthy role of the 6.7 μm water vapor absorption channel in improving the accuracy of the *** dependence of the accuracy of COMS OLRs on various surface,atmospheric,and observational conditions is also discussed.

关键词： outgoing longwave radiation Communication Oceanography and Meteorological Satellite Cloud and Earth's Radiant Energy System

Virtual Mold Technique in Thermal Stress Analysis during Casting Process

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Journal of Materials Science & Technology 2008年第3期24卷 359-363页

作者： Si-Young Kwak Jae-Wook Baek Jeong-ho Nam Jeong-Kil choi E-Design Center Korea Institute of Industrial Technology Department of Virtual Engineering Korea University of Science & Technology

It is important to analyse the casting product and the mold at the same time considering thermal contraction of the casting and thermal expansion of the mold. The analysis considering contact of the casting and the mold induces the precise prediction of stress distribution and the defect such as hot tearing. But it is difficult to generate FEM mesh for the interface of the casting and the mold. Moreover the mesh for the mold domain spends lots of computational time and memory for the analysis due to a number of meshes. Consequently we proposed the virtual mold technique which only uses mesh of the casting part for thermal stress analysis in casting process. The spring bar element in virtual mold technique is used to consider the contact of the casting and the mold. In general, a volume of the mold is much bigger than that of casting part, so the proposed technique decreases the number of mesh and saves the computational memory and time greatly. In this study, the proposed technique was verified by the comparison with the traditional contact technique on a specimen. And the proposed technique gave satisfactory results.

关键词： Casting process Thermal stress analysis Virtual mold

Formic acid as an alternative reducing agent for the catalytic nitrate reduction in aqueous media

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Journal of Environmental Sciences 2013年第8期25卷 1696-1702页

作者： Eun-kyoung choi Kuy-hyun Park ho-bin Lee Misun Cho Samyoung Ahn Department of Environmental Education Sunchon National University

Formic acid was used for the nitrate reduction as a reductant in the presence of Pd：Cu/γ-alumina catalysts. The surface characteristics of the bimetallic catalyst synthesized by wet impregnation were investigated by SEM, TEM-EDS. The metals were not distributed homogeneously on the surface of catalyst, although the total contents of both metals in particles agreed well with the theoretical values. Formic acid decomposition on the catalyst surface, its influence on solution pH and nitrate removal efficacy was investigated. The best removal of nitrate （50 ppm） was obtained under the condition of 0.75 g/L catalyst with Pd：Cu ratio （4：1） and two fold excess of formic acid. Formic acid decay patterns resembled those of nitrate removal, showing a linear relationship between kf （formic acid decay） and k （nitrate removal）. Negligible amount of ammonia was detected, and no nitrite was detected, possibly due to buffering effect of bicarbonate that is in situ produced by the decomposition of formic acid, and due to the sustained release of H2 gas.

关键词： formic acid catalytic nitrate reduction Pd:Cu/γ-alumina catalyst H2 supply

Effects of inter-electrode insertion on the performance and thermal flow fields of a hollow-electrode plasma torch

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Plasma Science and Technology 2020年第1期22卷 33-44页

作者： In-Mok YANG Jun-Seok NAM Min-Kyu choi Jun-ho SEO Shi-Young YANG Department of Applied Plasma Engineering Chonbuk National UniversityJeonju 54896Republic of Korea Graduate School of Flexible&Printable Electronics Chonbuk National UniversityJeonju 54896Republic of Korea

The effects of lntcr-ckxttxxk insertion on the performance of a hollow--electrode plasma torch have been investigated by numerical *** results revealed that when inter-dcctrodes arc inserted,the arc voltages and plasma powers increase due to the increase in the arc *** addition,it was predicted that thermal efficiency can be improved with the increase in plasma power by injecting plasma gases through the gaps between *** unique effects of inter-electrode insertion arc a result of the plasma temperatures adjusting themselves to increase arc voltages when the arc column is contracted radially by increasing gas-flow rate or decreasing inter-electrcxk diameter.

关键词： hollow-electrode plasma torch inter-electrodes numerical analysis torch performance