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Variability in Regional Ecological Vulnerability: A Case Study of Sichuan Province, China

International Journal of Disaster Risk Science 2020年第6期11卷 696-708页

作者： Yimeng Liu Saini Yang chuanliang han Wei Ni Yuyao Zhu Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing 100875China Academy of Disaster Reduction and Emergency Management Ministry of Emergency Management and Ministry of EducationFaculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China

Rapid urbanization and natural hazards are posing threats to local ecological processes and ecosystem services *** land use,socioeconomic,and natural hazards data,we conducted an assessment of the ecological vulnerability of prefectures in Sichuan Province for the years 2005,2010,and 2015 to capture variations in its capacity to modulate in response to disturbances and to explore potential factors driving these *** selected five landscape metrics and two topological indicators for the proposed ecological vulnerability index(EVI),and constructed the EVI using a principal component analysis-based entropy method.A series of correlation analyses were subsequently performed to identify the factors driving variations in ecological *** results show that:(1)for each of the study years,prefectures with high ecological vulnerability were located mainly in southern and eastern Sichuan,whereas prefectures in central and western Sichuan were of relatively low ecological vulnerability;(2)Sichuan’s ecological vulnerability increased significantly(p=0.011)during2005–2010;(3)anthropogenic activities were the main factors driving variations in ecological *** findings provide a scientific basis for implementing ecological protection and restoration in Sichuan as well as guidelines for achieving integrated disaster risk reduction.

关键词： Anthropogenic activities Ecological vulnerability Natural hazards PCA-based entropy method Rank correlation

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Lessons from the Mainland of China’s Epidemic Experience in the First Phase about the Growth Rules of Infected and Recovered Cases of COVID-19 Worldwide

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International Journal of Disaster Risk Science 2020年第4期11卷 497-507页

作者： chuanliang han Yimeng Liu Jiting Tang Yuyao Zhu Carlo Jaeger Saini Yang State Key Laboratory of Cognitive Neuroscience and Learning and IDG/Mc Govern Institute for Brain Research Beijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing 100875China Academy of Disaster Reduction and Emergency Management Ministry of Emergency Management and Ministry of EducationFaculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Global Climate Forum 10178 BerlinGermany

The first phase of the novel coronavirus disease(COVID-19)that emerged at the end of 2019 has been brought under control in the mainland of China in March,while it is still spreading *** the pandemic will end is a question of great concern.A logistic model that depicts the growth rules of infected and recovered cases in China’s mainland may shed some light on this *** model well explained the data by 13 April from 31 countries that have been experiencing serious COVID-2019 outbreaks(R2≥0.95).Based on this model,the semi-saturation period(SSP)of infected cases in those countries ranges from 3 March to 18 *** to the linear relationship between the growth rules for infected and for recovered cases identified from the Chinese data,we predicted that the SSP of the recovered cases outside China ranges from 22 March to 8 *** importantly,we found a strong positive correlation between the SSP of infected cases and the timing of a government’s ***,this model was also applied to four regions that went through other coronavirus or Ebola virus epidemics(R2≥0.95).There is a negative correlation between the death rate and the logistic growth *** findings provide strong evidence for the effectiveness of rapid epidemic control measures in various countries.

关键词： China COVID-2019 Epidemiological properties Logistic model Pandemic

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Thermally-induced cracking behaviors of coal reservoirs subjected to cryogenic liquid nitrogen shock

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 2894-2908页

作者： Songcai han Qi Gao Xinchuang Yan Lile Li Lei Wang Xian Shi chuanliang Yan Daobing Wang College of Energy Chengdu University of TechnologyChengdu610059China School of Engineering The University of Western Australia35 Stirling HighwayPerthWA6009Australia School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580China School of Mechanical Engineering Beijing Institute of Petrochemical TechnologyBeijing102617China

The benefits of using cryogenic liquid nitrogen shock to enhance coal permeability have been confirmed from experimental *** this paper,we develop a fully coupled thermo-elastic model in combination with the strain-based isotropic damage theory to uncover the cooling-dominated cracking behaviors through three typical cases,*** reservoirs containing a wellbore,a primary fracture,and a natural fracture network,*** progressive cracking processes,from thermal fracture initiation,propagation or cessation,deflection,bifurcation to multi-fracture interactions,can be well captured by the numerical *** is observed that two hierarchical levels of thermal fractures are formed,in which the number of shorter thermal fractures consistently exceeds that of the longer *** effects of coal properties related to thermal stress levels and thermal diffusivity on the fracture morphology are quantified by the fracture fractal dimension and the statistical fracture *** induced fracture morphology is most sensitive to changes in the elastic modulus and thermal expansion coefficient,both of which dominate the complexity of the fracture *** reservoir candidates with preferred thermal-mechanical properties are also recommended for improving the stimulation *** findings are that there exists a critical injection temperature and a critical in-situ stress difference,above which no thermal fractures would be *** natural fractures with higher density and preferred orientations are also essential for the formation of complex fracture *** obtained results can provide some theoretical support for cryogenic fracturing design in coal reservoirs.

关键词： Coal reservoirs Cryogenic shock Thermal cracking behaviors Fracture morphology

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Generation of Gamma Oscillation in Primary Visual Cortex(V1)

Generation of Gamma Oscillation in Primary Visual Cortex(V1)

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第四届全国神经动力学学术会议

作者： chuanliang han Yang Li Tian Wang Dajun Xing State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research Beijing Normal University

The gamma oscillation(30-80 Hz) of local field potential(LFP) is activated during some activecognitive states. Some previous work on macaques V1 showed that neural response and gammaoscillation in LFP are modulated by visual stimulus like drifting grating[1]. For example, whenchanging the size of the visual stimuli, gamma power of LFP gets stronger but peak frequencydecreases significantly, as well as the strength of neural response[2]. However, a model todescribe how connection of neurons affects this experimental phenomenon is not well *** in this work, firstly we constructed an E-I model as the basic unit of the whole network, whereE and I stand for local excitatory and inhibitory components. And then we largely increased thenumber of the basic units in visual cortex and connected, the parameters for neural connection are Gaussian decreased with distance. This model is based on groups of differential quations, bychoosing the proper parameters according to some previous work to achieve the simulation [3].The results showed that when we increased the connection of E and E, the gamma peak frequencygets smaller and the gamma power gets stronger, but the strength of neural response also *** when we further increased the connection between E and I, the property of gamma still holdsand neural response decreases, which matches the experimental results.

关键词： Gamma Oscillation Connection Primary Visual Cortex

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类器官在肝脏再生医学中的研究进展

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中华肝胆外科杂志 2024年第1期30卷 72-76页

作者：朱刘洋刘森崔涛杨龙程传梁韩品盛张雅敏天津医科大学一中心临床学院天津300070 沈阳药科大学生命科学与生物制药学院沈阳110016 天津药物研究院有限公司药物成药性评价与系统转化全国重点实验室天津30000 天津市第一中心医院肝胆外科天津300192 南开大学医学院天津300192

肝脏再生医学可利用功能性肝细胞修复或替代受损的肝组织,肝细胞或肝微组织移植有望作为肝移植的替代治疗方案得到了快速发展,但是再生医学需要有稳定增殖能力及肝细胞特性的细胞。肝脏类器官来源于成体干细胞或多能干细胞,可以在体外... 详细信息

肝脏再生医学可利用功能性肝细胞修复或替代受损的肝组织,肝细胞或肝微组织移植有望作为肝移植的替代治疗方案得到了快速发展,但是再生医学需要有稳定增殖能力及肝细胞特性的细胞。肝脏类器官来源于成体干细胞或多能干细胞,可以在体外大量增殖和长期培养,并保持遗传稳定性,模拟体内器官的结构和功能,为肝脏再生提供了新策略。本文对肝脏类器官以及其在肝脏再生医学中的研究进展进行综述,并探讨其应用潜力及存在的局限性。

关键词：类器官再生医学肝脏

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精神分裂症静息态下alpha活动和认知水平的相关性

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首都医科大学学报 2021年第1期42卷 117-124页

作者：沙莎赵希希韩传亮彭兴张培董雯尹晶晶王长明首都医科大学附属北京安定医院精神科国家精神疾病临床研究中心&北京市精神疾病重点实验室北京100088 北京师范大学认知神经科学与学习国家重点实验室/麦戈文脑研究所北京100875 华北理工大学公共卫生学院河北唐山063000

目的探究精神分裂症患者静息状态下的alpha频段能量和认知水平的相关性。方法本研究选取22例精神分裂症患者及23例匹配的健康对照,通过中文版精神分裂症认知功能成套测验(MATRICS Consensus Cognitive Battery,MCCB)评估其认知功能,同... 详细信息

目的探究精神分裂症患者静息状态下的alpha频段能量和认知水平的相关性。方法本研究选取22例精神分裂症患者及23例匹配的健康对照,通过中文版精神分裂症认知功能成套测验(MATRICS Consensus Cognitive Battery,MCCB)评估其认知功能,同时记录被试在睁眼和闭眼静息态下的脑电信号,比较两组在左侧额叶区(F3、F7)、右侧额叶区(F4、F8)、左侧中央区(T3、C3)、右侧中央区(T4、C4)、左后部脑区(T5、P3、O1)、右后部脑区(T6、P4、O2),以及中线Fz、CPz、Pz、Oz这4个位点的alpha相对功率,并探讨其与认知水平的相关性。结果除社会认知维度外,精神分裂症组在MCCB测验的其他各维度得分均显著低于正常对照(P<0.001)。在闭眼状态下,精神分裂症组全脑的alpha波相对功率均显著低于对照组(P<0.05);睁眼状态下,精神分裂症组的后部脑区,以及中线CPz、Pz、Oz电极alpha波相对功率均显著低于对照组(P<0.05)。在精神分裂症组,患者闭眼状态的所有脑区alpha波相对功率与其完成MCCB测评的总分,信息处理速度维度得分,推理和问题解决维度得分和言语学习与记忆维度得分均呈现正相关(P<0.05);患者睁眼状态的alpha波相对功率与其完成MCCB测评的总分,信息处理速度维度得分,言语学习与记忆维度得分均呈现正相关(P<0.05)。结论精神分裂症患者认知水平存在多维度损害,静息状态下alpha水平和患者信息处理速度,推理和问题解决及言语学习与记忆等认知能力存在正相关,提示静息状态下的alpha水平或可作为精神分裂症患者认知水平受损的生物学指标。

关键词：精神分裂症静息态脑电图 alpha 认知

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成人ADHD患者脑电α功率不对称性与生态执行功能的相关性

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中国心理卫生杂志 2021年第3期35卷 242-247页

作者：陈进赵希希韩传亮李卉吴占良钱秋谨曹庆久王长明孙黎王玉凤北京大学第六医院北京大学精神卫生研究所国家卫生健康委员会精神卫生学重点实验室(北京大学)国家精神心理疾病临床医学研究中心(北京大学第六医院)北京100083 首都医科大学附属北京安定医院国家精神疾病临床研究中心&北京市精神疾病重点实验室北京100088 认知神经科学与学习国家重点实验室/麦戈文脑研究所北京师范大学北京100875

目的:探究成人注意缺陷多动障碍(ADHD)患者静息态脑电α绝对功率不对称性与生态执行功能的相关性。方法:选取成人ADHD患者49例及正常对照45例,用执行功能行为评定量表成人版(BRIEF-A)评估生态执行功能,并记录静息态脑电,分析不同脑区α... 详细信息

目的:探究成人注意缺陷多动障碍(ADHD)患者静息态脑电α绝对功率不对称性与生态执行功能的相关性。方法:选取成人ADHD患者49例及正常对照45例,用执行功能行为评定量表成人版(BRIEF-A)评估生态执行功能,并记录静息态脑电,分析不同脑区α绝对功率不对称性差异并探讨其与生态执行功能的相关性。结果:ADHD患者双侧额部、前额的α绝对功率不对称性低于正常对照(均P0.05)。结论:成人ADHD患者生态执行功能存在缺陷,额部α绝对功率不对称性与自我监控能力关联性的消失可能是其执行功能受损的神经电生理机制。

关键词：注意缺陷多动障碍,脑电 α绝对功率不对称性生态执行功能

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基于3DMine煤矿矿体三维可视化模型建构研究

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煤炭技术 2024年第8期43卷 261-265页

作者：韩金伟崔毅斌张传良张地伟河南省地球物理空间信息研究院郑州450000 河南省地下工程探测信息工程技术研究中心郑州450000

以某露天煤矿为例,结合煤矿补勘资料,通过3DMine软件构建煤矿地表面模型、地质数据库以及附带地表显示的三维钻孔模型。同时,通过插值方法构建煤矿矿体全煤层模型,并分别利用3DMine软件自带露天设计功能和自动剖面图绘制功能,实施露天... 详细信息

以某露天煤矿为例,结合煤矿补勘资料,通过3DMine软件构建煤矿地表面模型、地质数据库以及附带地表显示的三维钻孔模型。同时,通过插值方法构建煤矿矿体全煤层模型,并分别利用3DMine软件自带露天设计功能和自动剖面图绘制功能,实施露天采矿模拟与煤矿地质剖面图绘制,完成煤矿矿体三维可视化模型建构过程,旨在为后续煤矿矿体三维可视化模型建构以及煤矿储量计算提供构建流程及模型参考。

关键词：煤矿矿体三维可视化模型构建 3DMine

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基于GIS和SWMM的西安市北郊片区排涝模拟与排水系统优化

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给水排水 2024年第3期50卷 134-141,147页

作者：杨利伟刘家华周煜欣邢雯雯陈宏伟赵传靓路鹏韩诚长安大学建筑工程学院西安710064 中国建筑设计研究院有限公司北京100044

为解决西安市北郊河道超载风险问题,通过SWMM和GIS技术构建管网-泵站-河道耦合模型,在不同设计降雨重现期(1、2、5、10、20、50年)下对该区域排水系统进行模拟,进而分析下游河道水位变化规律并提出雨水分流调配与调整泵站调度的协同优... 详细信息

为解决西安市北郊河道超载风险问题,通过SWMM和GIS技术构建管网-泵站-河道耦合模型,在不同设计降雨重现期(1、2、5、10、20、50年)下对该区域排水系统进行模拟,进而分析下游河道水位变化规律并提出雨水分流调配与调整泵站调度的协同优化措施。结果显示:在5、10、20和50年降雨重现期下,随着降雨峰值的到达,整个系统88%的排口都存在顶托现象,最长持续时间160min。在重现期为1、2、5和10年降雨条件下,协同优化的措施使得河道峰值流量分别下降了17.6%、4.9%、3.7%和2.6%,河道水位平均下降了35cm,排水系统的超载节点分别减少了16.7%、31.4%、34.2%和27.5%,超载管段的数量分别减少了25.0%、28.6%、30.8%和25.3%。

关键词： SWMM 城市防涝 GIS 雨洪模拟排水系统优化雨水泵站

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The natural course of bacillus Calmette-Guerin induced bladder lesions:A long-term follow-up study and systematic review

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Asian Journal of Urology 2023年第3期10卷 356-363页

作者： Chong Ma Shuxiong Zeng Lihe Dai Huan han Ruixiang Song Jinshan Xu Xing Ai chuanliang Xu Department of Urology The Third Medical Center of PLA General HospitalBeijingChina Department of Urology Changhai HospitalNaval Medical UniversityShanghaiChina Department of Urology The 943 Hospital of Joint Logistics Support Force of Chinese PLAGansuChina Department of Pathology Changhai HospitalNaval Medical UniversityShanghaiChina

Objective:Bacillus Calmette-Gue´rin(BCG)instillation is the standard adjuvant treatment for intermediate-and high-risk non-muscle-invasive bladder cancer after transurethral ***,its toxicity often causes bladder *** follow-up cystoscopy,post-BCG bladder lesions can be pathologically benign,urothelial carcinoma recurrence,or other types of bladder *** a small number of case reports have been published on post-BCG bladder *** clinical features,natural course,and management remain ***:We retrospectively studied cystoscopic videos and medical records of BCG-treated bladder cancer patients at our *** a long-term follow-up,we took biopsies on tumor-like lesions and described their *** addition,we summarized previous studies on post-BCG bladder lesions by systematic literature searching and ***:We described a series of three cases with post-BCG bladder lesions mimicking tumor recurrence from a total of 38 cases with follow-up data for more than 5 *** lesions could last,grow,or disappear spontaneously,and remain pathological benign for *** systematic review,we identified and analyzed a total of 15 cases with post-BCG bladder lesions with detailed clinical *** of the 15 were benign and have a good prognosis with nephrogenic adenoma being the most common pathological ***:Based on previous studies and our experience,benign lesions after BCG instillation cannot distinguish with cancer recurrence by cystoscopy alone,even under narrow band imaging ***,given most of them have a good prognosis,random biopsy or transurethral resection might be spared in the patients with long-term negative biopsy and urine cytology.

关键词： Bacillus Calmette-Guerin Bladder cancer Side effects Cystoscopy Follow-up

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