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Prediction of cutting power and surface quality, and optimization of cutting parameters using new inference system in high-speed milling process

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Advances in Manufacturing 2021年第3期9卷 388-402页

作者： Long-Hua Xu chuan-zhen huang Jia-Hui Niu Jun Wang Han-Lian Liu Xiao-Dan Wang Center for Advanced Jet Engineering Technologies Key Laboratory of High-efficiency and Clean Mechanical Manufacture(Ministry of Education)National Experimental Teaching Demonstration Center for Mechanical Engineering(Shandong University)School of Mechanical EngineeringShandong UniversityJinanPeople’s Republic of China School of Mechanical and Manufacturing Engineering The University of New South Wales(UNSW)SydneyNSW2052Australia Department of Computer Science and Software Engineering Xi’an Jiaotong-Liverpool UniversitySuzhou215123JiangsuPeople’s Republic of China

During the actual high-speed machining process,it is necessary to reduce the energy consumption and improve the machined surface ***,the appropriate prediction models and optimal cutting parameters are difficult to obtain in complex machining ***,a novel intelligent system is proposed for prediction and optimization.A novel adaptive neuro-fuzzy inference system(NANFIS)is proposed to predict the energy consumption and surface *** the NANFIS model,the membership functions of the inputs are expanded into:membership superior and membership *** membership functions are varied based on the machining *** inputs of the NANFIS model are cutting parameters,and the outputs are the machining *** optimization,the optimal cutting parameters are obtained using the improved particle swarm optimization(IPSO)algorithm and NANFIS ***,the IPSO algorithm as a learning algorithm is used to train the NANFIS *** proposed intelligent system is applied to the high-speed milling process of compacted graphite *** experimental results show that the predictions of energy consumption and surface roughness by adopting the NANFIS models are up to 91.2%and 93.4%,*** NANFIS models can predict the energy consumption and surface roughness more accurately compared with other intelligent *** on the IPSO algorithm and NANFIS models,the optimal cutting parameters are obtained and validated to reduce both the cutting power and surface roughness and improve the milling *** is demonstrated that the proposed intelligent system is applicable to actual high-speed milling processes,thereby enabling sustainable and intelligent manufacturing.

关键词： Novel adaptive neuro-fuzzy inference system(NANFIS)model Improved particle swarm optimization(IPSO)algorithm Energy consumption Surface roughness Multiobjective optimization

Coupling effect of micro-textured tools and cooling conditions on the turning performance of aluminum alloy 6061

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Advances in Manufacturing 2023年第4期11卷 663-681页

作者： Guo-Liang Liu Jin-Tao zheng chuan-zhen huang Shu-Feng Sun Xin-Fu Liu Long-Jie Dai De-Xiang Wang Xiang-Yu Wang Key Lab of Industrial Fluid Energy Conservation and Pollution Control Ministry of EducationKey Lab of Industrial Fluid Energy Conservation and Pollution ControlMinistry of EducationSchool of Mechanical and Automotive EngineeringQingdao University of TechnologyQingdao266520ShandongPeople’s Republic of China State Key Laboratory of High Performance Complex Manufacturing Central South UniversityChangsha410083People’s Republic of China Key Laboratory of High-Efficiency and Clean Mechanical Manufacture(Ministry of Education) School of Mechanical EngineeringShandong UniversityJinan250061People’s Republic of China School of Mechanical Engineering Yanshan UniversityQinhuangdao066004HebeiPeople’s Republic of China Qingdao Choho Ind Co Ltd Qingdao266705ShandongPeople’s Republic of China School of Mechanical Engineering University of JinanJinan250022People’s Republic of China

Micro-texturing has been widely proven to be an effective technology for achieving sustainable ***,the performance of micro-textured tools under different cooling conditions,especially their coupling effect on machined surface integrity,was scarcely *** this paper,the non-textured,linear micro-grooved,and curvilinear micro-grooved inserts were used to turn aluminum alloy 6061 under dry,emulsion,and liquid nitrogen cryogenic cooling *** coupling effects of different micro-textures and cooling conditions on cutting force,cutting temperature,and machined surface integrity,including the surface roughness,work hardening,and residual stress,were revealed and discussed in *** indicated that the micro-grooved tools,especially the curvilinear micro-grooved tools,not only reduced the cutting force and cutting temperature,but also improved the machined surface *** addition,the micro-grooved tools can cooperate with the emulsion or liquid nitrogen to reduce the cutting force,cutting temperature,and improve the machined surface integrity generally,although the combination of emulsion cooling condition and micro-grooved tools generated negative coupling effects on cutting forces and surface work ***,the combination of curvilinear micro-grooved cutting tools and cryogenic cooling condition resulted in the lowest cutting force and cutting temperature,which generated the surface with low roughness,weak work hardening,and compressive residual stress.

关键词： Micro-grooved cutting tool Cooling condition Cutting force Cutting temperature Surface integrity

Integration of Electrical Properties and Polarization Loss Modulation on Atomic Fe–N‑RGO for Boosting Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 517-532页

作者： Kaili Zhang Yuefeng Yan zhen Wang Guansheng Ma Dechang Jia Xiaoxiao huang Yu Zhou State Key Laboratory of Precision Welding&Joining of Materials and Structures Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China MIIT Key Laboratory of Advanced Structural‑Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Developing effective strategies to regulate graphene’s conduction loss and polarization has become a key to expanding its application in the electromagnetic wave absorption(EMWA)*** on the unique energy band structure of graphene,regulating its bandgap and electrical properties by introducing heteroatoms is considered a feasible ***,metal-nitrogen doping reduced graphene oxide(M–N-RGO)was prepared by embedding a series of single metal atoms M–N_(4) sites(M=Mn,Fe,Co,Ni,Cu,Zn,Nb,Cd,and Sn)in RGO using an N-coordination atom-assisted *** composites had adjustable conductivity and polarization to optimize dielectric loss and impedance matching for efficient EMWA *** results showed that the minimum reflection loss(RL_(min))of Fe–N-RGO reaches−74.05 dB(2.0 mm)and the maximum effective absorption bandwidth(EAB_(max))is 7.05 GHz(1.89 mm)even with a low filler loading of only 1 wt%.Combined with X-ray absorption spectra(XAFS),atomic force microscopy,and density functional theory calculation analysis,the Fe–N_(4) can be used as the polarization center to increase dipole polarization,interface polarization and defect-induced polarization due to d-p orbital hybridization and structural ***,electron migration within the Fe further leads to conduction loss,thereby synergistically promoting energy *** study demonstrates the effectiveness of metal-nitrogen doping in regulating the graphene′s dielectric properties,which provides an important basis for further investigation of the loss mechanism.

关键词： Electromagnetic wave absorption Fe-N-RGO Dipole polarization Conduction loss Impedance matching

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Mechanical Properties of Railway High-strength Manufactured Sand Concrete: Typical Lithology, Stone Powder Content and Strength Grade

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 194-203页

作者： WANG zhen LI Huajian huang Fali YANG Zhiqiang WEN Jiaxin SHI Henan Railway Engineering Research Institute China Academy of Railway Science Corporation LimitedBeijing 100081China State Key Laboratory for Track Technology of High-Speed Railway Beijing 100081China

In order to achieve the large-scale application of manufactured sand in railway high-strength concrete structure,a series of high-strength manufactured sand concrete(HMC)are prepared by taking the manufactured sand lithology(tuff,limestone,basalt,granite),stone powder content(0,5%,10%,15%)and concrete strength grade(C60,C80,C100)as *** evolution of mechanical properties of HMC and the correlation between cubic compressive strength and other mechanical properties are *** to river sand,manufactured sand enhances the cubic compressive strength,axial compressive strength and elastic modulus of concrete,while its potential microcracks weaken the flexural strength and splitting tensile strength of *** powder content displays both positive and negative effects on mechanical properties of HMC,and the stone powder content is suggested to be less than 10%.The empirical formulas between cubic compressive strength and other mechanical properties are proposed.

关键词： manufactured sand concrete railway mechanical property lithology stone powder content

A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao Liang Xingping Quan Xiaorui Geng Yujing huang Yonghua Zhao Lei Xi zhen Yuan Ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell invasion by inhibition of MMP-2 expression and its activation

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Acta Pharmacologica Sinica 2006年第12期27卷 1600-1607页

作者： Mao-chuan zhen Xiao-hui huang Qian WANG~2 Kai SUN Yun-jian LIU Wen LI Long-juan ZHANG Liang-qi CAO Xi-ling CHEN Department of Hepatobiliary Surgery,the First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,China DepartmentofHepatobiliarySurgery theFirstAffiliatedHospitalofSunYat-SenUniversityGuangzhou510080China

Aim:Epigallocatechin-3-gallate(EGCG)is the major component of green teapolyphenols,whose wide range of biological properties includes *** metalloproteinases(MMP)that participate in extracellular matrixdegradation are involved in the development of hepatic *** presentstudy investigates whether EGCG inhibits activation of the major gelatinase matrixmetalloproteinase-2(MMP-2)in rat hepatic stellate cells(HSC).Methods:Theexpression of MMP-2,tissue inhibitors of metalloproteinases-2(TIMP-2),andmembrane-type 1-MMP(MT1-MMP)was assessed by RT-PCR and Western ***-2 activity was evaluated by zymography and MT1-MMP activitywas assessed by an enzymatic *** migration was measured by a woundhealing assay and cell invasion was performed using Transwell cell ***:The expression of MMP-2 mRNA and protein in HSC wassubstantially reduced by EGCG *** treatment also reduced con-canavalin A(ConA)-induced activation of secreted MMP-2 and reduced MT1-MMP activity in a dose-dependent *** addition,EGCG inhibited eitherHSC migration or ***:The abilities of EGCG to suppress MMP-2 activation and HSC invasiveness suggest that EGCG may be useful in the treat-ment and prevention of hepatic fibrosis.

关键词： matrix metalloproteinase hepatic stellate cell green tea migration invasion

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-Wei Wang Jing-Shui zhen Bo-Cheng Li De-Cheng Cai Yang-Yang Du Hui huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

Systematical identification of regulatory GPCRs by single-cell trajectory inference reveals the role of ADGRD1 and GPR39 in adipogenesis

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Science China Life Sciences 2025年

作者： chuan Ye Xuemei Wang Jun Lin Chenyang Wu Yuhua Gao Chenghao Guo Yunxi Liao Ziyan Rao Shaodong huang Weixuan Chen Ying huang Jinpeng Sun Dongyu Zhao Changtao Jiang Center of Basic Medical Research Institute of Medical Innovation and ResearchPeking University Third Hospital Department of Physiology and Pathophysiology School of Basic Medical SciencesPeking University Department of Biomedical Informatics School of Basic Medical SciencesPeking University State Key Laboratory of Vascular Homeostasis and Remodeling Peking University Center for Obesity and Metabolic Disease Research School of Basic Medical SciencesPeking University State Key Laboratory of Female Fertility Promotion Center for Reproductive MedicineDepartment of Obstetrics and GynecologyPeking University Third Hospital National Clinical Research Center for Obstetrics and Gynecology Peking University Third Hospital Department of Endocrinology and Metabolism Peking University Third Hospital Key Laboratory Experimental Teratology of the Ministry of Education Department of Biochemistry and Molecular BiologySchool of Basic Medical SciencesCheeloo College of MedicineShandong University Department of Immunology School of Basic Medical SciencesPeking University

Adipogenesis is the healthy expansion of white adipose tissue (WAT),serving as a compensatory response to maintain metabolic homeostasis in the presence of excess energy in the ***,the identification of novel regulatory molecules in adipogenesis,specifically membrane receptors such as G protein-coupled receptors (GPCRs),holds significant clinical *** receptors can serve as viable targets for pharmaceuticals,offering potential for restoring metabolic homeostasis in individuals with *** utilized trajectory inference methods to analyze three distinct single-nucleus sequencing (sNuc-seq) datasets of adipose tissue and systematically identified GPCRs with the potential to regulate *** verification in primary adipose progenitor cells (APCs) of mice,we discovered that ADGRD1 promoted the differentiation of APCs,while GPR39 inhibits this *** the obese mouse model induced by a high-fat diet(HFD),both gain-of-function and loss-of-function studies validated that ADGRD1 promoted adipogenesis,thereby improving metabolic homeostasis,while GPR39 inhibited adipogenesis,leading to metabolic ***,through the analysis of 2,400 ChIP-seq data and 1,204 bulk RNA-seq data,we found that the transcription factors (TFs) MEF2D and TCF12 regulated the expression of ADGRD1and GPR39,*** study revealed the regulatory role of GPCRs in adipogenesis,providing novel targets for clinical intervention of metabolic dysfunction in obese patients.

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Design of a terahertz slotted waveguide array antenna based on photonic crystal

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Optoelectronics Letters 2025年

作者： PAN Wu YE Kuan ZHANG zhen LI Renpu QIU Sen huang Lei College of Photoelectronic Engineering， Chongqing University of Posts and Telecommunications Chongqing Municipal Key Laboratory of Photoelectric Information Sensing and Transmission Technology， Chongqing University of Posts and Telecommunications Laboratory of Quantum Information Technology， Chongqing University of Posts and Telecommunications

In this paper， a terahertz slotted waveguide array antenna is designed based on photonic crystal， which can realize efficient radiation of terahertz waves. The electromagnetic wave is fed from the rectangular waveguide at the bottom of the antenna， coupled to photonic crystal waveguide through photonic crystal cavity， and radiated outward through slots at the top layer of antenna. The simulation results show that the antenna achieves a peak gain of 13.45dBi at 360 GHz， a half-power beamwidth of 10.9o， and a side lobe level of -13.9dB. The antenna based on photonic crystal has the advantages of low profile， low loss， and high radiation efficiency， which can be applied to terahertz wireless communication systems.

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