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Asian Journal of Andrology 2014年第4期16卷 602-606页

作者： Sandro C Esteves Christina Prudencio Bill Seol Sidney Verza jr christopher knoedler Ashok Agarwal ANDROFERT Center for Male Reproduction Campinas Brazil Center for Reproductive Medicine The Cleveland Clinic Foundation Cleveland USA.

We assessed the rates of sperm retrieval and intracytoplasmic sperm injection outcomes, including the neonatal profile of infants conceived, in men with testicular failure. Three-hundred and sixty-five men with testicular failure who underwent micro-dissection testicular sperm extraction were included in this study. We compared their outcomes with 40 men with testicular failure who used donor sperm for injections due to failed retrieval, and 146 men with obstructive azoospermia who underwent percutaneous sperm retrieval. The retrieval rate in testicular failure was 41.4%, and the results were lower than the obstructed azoospermia （100%; adjusted odds ratio： 0.033; 95% Ch 0.007-0.164; P 〈 0.001）. Live birth rates after sperm injections were lower in men with testicular failure （19.9%） compared with donor sperm （37.5%; adjusted OR： 0.377 （95% Ch 0.233-0.609, P 〈 0.001）） and obstructive azoospermia （34.2%; adjusted OR： 0.403 （95% CI： 0.241-0.676, P= 0.001）. Newborn parameters of infants conceived were not significantly different among the groups. We concluded that the chances of obtaining sperm on retrieval and achieving a live birth after intracytoplasmic sperm injection （ICSI） are reduced in men with testicular failure. The profile of infants conceived after sperm injection does not seem to be negatively affected by testicular failure.

关键词： infant intracytoplasmic sperm injection obstructive azoospermia pregnancy outcome sperm retrieval testicular failure

Magnetosymbiosis discovery:new perspectives in magnetotaxis research

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Journal of Oceanology and Limnology 2025年第1期43卷 177-186页

作者： Caroline L.MONTEIL christopher T.LEFEVRE Aix-Marseille Université CEACNRSInstitute of Biosciences and Biotechnologies of Aix-MarseilleSaint-Paul-lez-Durance 13115France

Magnetotactic bacteria have been the only known magnetoreceptive microorganisms for *** if the existence of magnetotactic protists was suggested in 1986,this is only 30 years later that magnetotaxis was extended to the domain of Eukaryota,thanks to the characterization of magnetotactic symbiotic assemblies composed of a flagellated protist and bacteria biomineralizing magnetic *** mutualistic ectosymbiosis relies on a collective magnetotaxis coupled to a hydrogen-based *** new form of cooperation challenges our view of magnetic biomineralization in prokaryotes and magnetoreception in *** this review,we present how magnetosymbiosis was discovered and how cooperation ***,we discuss the future research and the new perspectives such discovery brought to the field of magnetotaxis.

关键词： magnetotaxis biomineralization symbiosis magnetotactic

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： christopher J.O’Connell Matthew J.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA James L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Comparative analysis of empirical and deep learning models for ionospheric sporadic E layer prediction

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Earth and Planetary Physics 2025年第1期9卷 10-19页

作者： BingKun Yu PengHao Tian XiangHui Xue christopher JScott HaiLun Ye JianFei Wu Wen Yi TingDi Chen XianKang Dou Institute of Deep Space Sciences Deep Space Exploration LaboratoryHefei 230088China CAS Key Laboratory of Geospace Environment School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China Department of Meteorology University of ReadingReading RG66BBUK

Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 *** they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite *** this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde *** deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular.

关键词： ionospheric sporadic E layer radio occultation ionosondes numerical model deep learning model artificial intelligence

The Current State of Kidney Transplantation in Kenya: Challenges, Opportunities, and Future Directions

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International Journal of Clinical Medicine 2025年第1期16卷 89-94页

作者： christopher Owino Ann Mutugi Mathew Koech Jie Tang Department of Medicine Moi University Eldoret Kenya Division of Kidney Diseases and Hypertension Alpert Medical School of Brown University Providence RI USA

Kenya, a lower-middle-income country in East Africa, faces a rising burden of chronic kidney disease (CKD), with an estimated 12,500 individuals suffering from end-stage renal disease (ESRD). Renal transplantation—the preferred treatment option for ESRD, remains underutilized. Since the first transplant in 1978, seven centers have been established, with 829 transplants performed by 2022. Living-related renal transplants (LRRT) dominate, while deceased donor renal transplantation (DDRT) is yet to be implemented. Recent data show improved outcomes, with one-year graft survival rates up to 96%, but challenges such as acute rejection rates (32.8%) and limited donor outcome data persist. Barriers include high costs, limited insurance coverage, inadequate laboratory infrastructure, and a transplant workforce shortage. Efforts to establish DDRT programs are underway but are hampered by the absence of organ procurement systems and insufficient laboratory capabilities. Future priorities include reducing costs and expanded insurance coverage for transplant care. Investments in laboratory infrastructure, local tissue typing, and surgical training are essential. Strengthening international collaborations and public education campaigns can improve donor pools and transplantation access. Strategic policy reforms and resource allocation are vital to scaling up Kenya’s kidney transplant program and addressing the unmet needs of its ESRD population.

关键词： Kidney Transplant Outcomes Chronic Kidney Disease End Stage Renal Disease

A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts

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Neural Regeneration Research 2025年第12期20卷 3539-3552页

作者： Jessica Wiseman Raja Haseeb Basit Akihiro Suto Sagnik Middya Bushra Kabiri Michael Evans Vinoj George christopher Adams George Malliaras Divya Maitreyi Chari School of Medicine Keele UniversityNewcastle-under-LymeUK Sheffield Institute for Translational Neuroscience University of SheffieldSheffieldUK Academic Department of Surgery Queen Elizabeth Hospital&University of BirminghamEdgbastonUK Guy Hilton Research Center School of Pharmacy&BioengineeringKeele UniversityNewcastle-under-LymeUK Electrical Engineering Division Department of EngineeringUniversity of CambridgeCambridgeUK School of Life Sciences Keele UniversityNewcastle-under-LymeUK

Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative *** therapies show promise as medical materials for neural repair through immunomodulation,structural support,and delivery of therapeutic ***,a lack of facile and pathology-mimetic models for therapeutic testing is a bottleneck in neural tissue engineering *** have deployed a two-dimensional,high-density multicellular cortical brain sheet to develop a facile model of injury(macrotransection/scratch wound)in *** model encompasses the major neural cell types involved in pathological responses ***,we observed hallmark pathological responses in injury foci including cell scarring,immune cell infiltration,precursor cell migration,and shortrange axonal *** test magnetic particles to evaluate the potential of the model for biomaterial screening shows a high uptake of introduced magnetic particles by injury-activated immune cells,mimicking in vivo ***,we proved it is feasible to create reproducible traumatic injuries in the brain sheet(in multielectrode array devices in situ)characterized by focal loss of electrical spiking in injury sites,offering the potential for longer term,electrophysiology plus histology *** our knowledge,this is the first in vitro simulation of transecting injury in a two-dimensional multicellular cortical brain cell sheet,that allows for combined histological and electrophysiological readouts of damage/*** patho-mimicry and adaptability of this simplified model of brain injury could benefit the testing of biomaterial therapeutics in regenerative neurology,with the option for functional electrophysiological readouts.

关键词： in vitro modelling multielectrode array interfacing nanoparticles neuromaterials scratch assay transecting injury traumatic brain injury

In situ spontaneous emission control of MoSe2-WSe2 interlayer excitons with high quantum yield

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Photonics Research 2025年第1期13卷 210-224页

作者： BO HAN CHIRAG C.PALEKAR FREDERIK LOHOF SVEN STEPHAN VICTOR N.MITRYAKHIN JENS-CHRISTIAN DRAWER ALEXANDER STEINHOFF LUKAS LACKNER MARTIN SILIES BáRBARA ROSA MARTIN ESMANN FALK EILENBERGER christopher GIES STEPHAN REITZENSTEIN CHRISTIAN SCHNEIDER Institut für Physik Fakult?t VCarl von Ossietzky Universit?t Oldenburg Institut für Festk?rperphysik Technische Universit?t Berlin Institute for Theoretical Physics and Bremen Center for Computational Material Science Universit?t Bremen Institute for Lasers and Optics Hochschule Emden/Leer Fraunhofer-Institute for Applied Optics and Precision Engineering IOF Institute of Applied Physics Abbe Center of PhotonicsFriedrich Schiller Universit?t Jena Max Planck School of Photonics

Optical resonators are a powerful platform to control the spontaneous emission dynamics of excitons in solidstate nanostructures. We study a MoSe2-WSe2heterostructure that is integrated in a cryogenic open optical microcavity to gain insights into fundamental optical properties of the emergent interlayer excitons. First, we utilize a low-quality-factor planar open cavity and investigate the modification of the excitonic lifetime as on-and offresonance conditions are met with consecutive longitudinal modes.

关键词： Cavity quantum electrodynamics Nanostructures Optical properties Optical resonators Quantum fluctuations Zeeman effect

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Power-to-X在电解水制氢中的应用

流程工业 2025年第1期 44-46页

作者： christopher Lenz EnviroFALK

质子交换膜电解(PEM电解)在Power-to-X技术中,尤其是在氢气制备方面,起着至关重要的作用。随着清洁能源需求的增长,PEM电解作为一种高效、紧凑且响应迅速地水电解技术,受到了广泛关注。在此背景下,超纯水作为PEM电解过程中的核心原料,... 详细信息

质子交换膜电解(PEM电解)在Power-to-X技术中,尤其是在氢气制备方面,起着至关重要的作用。随着清洁能源需求的增长,PEM电解作为一种高效、紧凑且响应迅速地水电解技术,受到了广泛关注。在此背景下,超纯水作为PEM电解过程中的核心原料,其质量直接决定了氢气生产的效率和纯度。为了满足PEM电解对水质的严格要求,用于制备超纯水的设备必须达到高标准。

关键词：电解水制氢超纯水氢气制备氢气生产质子交换膜电解过程清洁能源 Power

A comprehensive framework for the delimitation of species within the Bemisia tabaci cryptic complex,a global pest-species group

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Insect Science 2025年第1期32卷 321-342页

作者： Hua-Ling Wang Teng Lei Xiao-Wei Wang Stephen Cameron Jesús Navas-Castillo Yin-Quan Liu M.N.Maruthi christopher A.Omongo Hélène Delatte Kyeong-Yeoll Lee Renate Krause-Sakate James Ng Susan Seal Elvira Fiallo-Olivé Kathryn Bushley John Colvin Shu-Sheng Liu College of Forestry Hebei Agricultural UniversityBaodingHebei ProvinceChina The Ministry of Agriculture Key Laboratory of Molec ular Biology of Crop Pathogens and Insects Institute of Insect SciencesZhejiang UniversityHangzhouChina Natural Resources Institute University of GreenwichKentUK College of Life Sciences Taizhou UniversityTaizhouZhejiang ProvinceChina Department of Entomology Purdue UniversityWest LafayetteINUSA Instituto de Hortofruticultura Subtropical y Mediterranea"La Mayora"(IHSMUMA-CsiC) Consejo Superior de Investigaciones CientificasMalagaSpain National Crops Resources Research Institute KampalaUganda CIRAD UMR PVBMT CIRADPole de Protection des PlantesSaint-PierreFrance School of Applied Biosciences Kyungpook National UniversityDaeguRepublic of Korea uNESP Faculdade de Ciencias AgronomicasBotucatuBrazil Department of Microbiology and Plant Pathology University of CaliforniaRiversideCA uSDA Agricultural Research Service 17123Emerging Pests and Pathogens Research UnitIthacaNYUSA

Identifying cryptic species poses a substantial challenge to both biologists and naturalists due to morphological *** tabaci is a cryptic species complex containing more than 44 putative species;several of which are currently among the world's most destructive crop *** and delimiting the evolution of this species complex has proved *** develop a comprehensive framework for species delimitation and identification,we evaluated the performance of distinct data sources both individually and in combination among numerous samples of the *** species complex acquired *** datasets include full mitogenomes,single-copy nuclear genes,restriction site-associated DNA sequencing,geographic range,host speciation,and reproductive compatibility ***,our well-supported topologies generated from three dense molecular markers highlighted the evolutionary divergence of species of the *** complex and suggested that the nuclear markers serve as a more accurate representation of *** species *** compatibility datasets facilitated the identification of at least 17 different cryptic species within our *** geographic range information provides a complementary assessment of species recognition,while the host range datasets provide low rate of delimiting *** further summarized different data performances in species classification when compared with reproductive compatibility,indicating that combination of mtCOI divergence,nuclear markers,geographic range provide a complementary assessment of species ***,we represent a model for understanding and untangling the cryptic species complexes based on the evidence from this study and previously published articles.

关键词： Bemisia tabaci cryptic species phylogenetics RAD-Seq reproductive compatibility whiteflies

Protecting miners from coal bursts during development above historic mine workings in Harlan County,KY

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International Journal of Mining Science and Technology 2021年第1期31卷 111-116页

作者： christopher Mark Mine Safety and Health Administration PittsburghPA 15236USA

In order to reach a large,untapped reserve of high-quality coal,D8 Cloverlick Mine proposed to mine a corridor nearly 600 m deep beneath the Benham Spur of Black Mountain,Kentucky’s highest peak.D8 Cloverlick Mine was extracting the Owl seam,but the corridor’s route lay approximately 20 m above century-old mine workings in the C–(Darby)*** to the concern,three serious coal bursts had recently occurred in nearby Owl seam *** of the old workings seemed to indicate that the underlying C–seam had been fully ***,two of the coal bursts had occurred above areas where the C–Seam was also shown as mined *** Safety and Health Administration(MSHA)Technical Support therefore investigated the records of past mining to better understand the old mine *** conditions observed in current Owl seam workings were also compared with the maps of the old C–seam *** study concluded that the presence of hazardous underlying remnants could not be ruled *** mitigate the burst risk,D8 Cloverlick Mine adopted a strategy of stress probe drilling.A self-propelled coal drill was used to auger 11.5-m-long,small diameter holes in advance of *** each hole was drilled,the cuttings were measured to detect the presence of highly stressed *** the crossing was successfully completed without incident.

关键词： Coal bursts Underground mining Room-and-pillar Destressing