检索结果-南通市图书馆

Associations between aerobic and muscle-strengthening physical activity,sleep duration,and risk of all-cause mortality:A prospective cohort study of 282,473 ***

引用

Journal of Sport and Health Science 2023年第1期12卷 65-72页

作者： Mitch J.Duncan Stina Oftedal christopher e kline Ronald C.Plotnikoff elizabeth G.Holliday School of Medicine&Public Health College of HealthMedicineand WellbeingThe University of NewcastleCallaghanNSW 2308Australia Priority Research Centre for Physical Activity and Nutrition The University of NewcastleCallaghanNSW 2308Australia Department of Health&Human Development The University of PittsburghPittsburghPA 15261USA School of education University of NewcastleCallaghanNSW 2308Australia

Purpose:To examine the joint associations between meeting guidelines for physical activity(PA)and sleep duration and all-cause mortality risk among ***:Participants were adults(n=282,473)aged 18-84 years who participated in the 2004-2014 *** Health Interview *** status was ascertained using the National Death Index through December ***-reported PA(Active:meeting both aerobic(AeR)and muscle-strengthening(MSA)guidelines,AeR only(AeR),MSA only(MSA),or not meeting either AeR or MSA(Inactive))and sleep duration(Short,recommended(Rec),or Long)were classified according to guidelines,and 12 PA-sleep categories were *** hazard ratios and 95%confidence intervals(95%CIs)for all-cause mortality risk were estimated using Cox proportional hazards regression ***:A total of 282,473 participants(55%females)were included;18,793 deaths(6.7%)occurred over an average follow-up of 5.4 *** to the Active-Rec group,all other PA-sleep groups were associated with increased mortality risk except for the Active-Short group(hazard ratio=1.08;95%CI:0.92-1.26).The combination of long sleep with either MSA or Inactive appeared to be *** a given sleep duration,mortality risk progressively increased among participants classified as AeR,MSA,and *** each activity level,the mortality risk was greatest among adults with long ***:Relative to adults meeting guidelines for both PA and sleep duration,adults who failed to meet guidelines for both AeR and muscle strengthening PA and who also failed to meet sleep duration guidelines had elevated all-cause mortality *** results support interventions targeting both PA and sleep duration to reduce mortality risk.

关键词： Activity-sleep patterns All-cause mortality Prospective Resistance training

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Music as medicine for traumatic brain injury:a perspective on future research directions

引用

Neural Regeneration Research 2024年第10期19卷 2105-2106页

作者： Anthony e.kline eleni H.Moschonas Corina O.Bondi Department of Physical Medicine&Rehabilitation University of PittsburghPittsburghPAUSA Safar Center for Resuscitation Research University of PittsburghPittsburghPAUSA Center for Neuroscience University of PittsburghPittsburghPAUSA Department of Critical Care Medicine University of PittsburghPittsburghPAUSA Center for the Neural Basis of Cognition University of PittsburghPittsburghPAUSA Department of Psychology University of PittsburghPittsburghPAUSA Department of Neurobiology University of PittsburghPittsburghPAUSA

Traumatic brain injury(TBI) impacts 69 million individuals globally each year and is a leading cause of death and disability(Dewan et al.,2019).The majority of moderate-to-severe TBI survivors endure long-lasting disturbances in motor,cognitive,and affect that negatively impacts their *** a plethora of research on pharmacological interventions for TBI has been conducted,none has translated to the clinic,thus advocating for the evaluation of nonpharmacological therapeutic approaches that may increase translational success.

关键词： injury traumatic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

exotic and excited-state meson spectroscopy and radiative transitions from lattice QCD

引用

Chinese Physics C 2010年第9期34卷 1512-1515页

作者： christopher e.Thomas Jefferson Laboratory

We discuss recent progress in extracting the excited meson spectrum and radiative transition form factors from lattice *** mention results in the charmonium sector,including the first lattice QCD calculation of radiative transition rates involving excited charmonium states,highlighting results for high spin and exotic *** present recent results on a highly excited isovector meson spectrum from dynamical anisotropic *** carefully constructed operators we show how the continuum spin of extracted states can be reliably identified and confidently extract excited states,states with exotic quantum numbers and states of high *** spectrum includes the first spin-four state extracted from lattice *** conclude with some comments on future prospects.

关键词： lattice QCD exotics mesons spectroscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical variability and molecular heterogeneity inprostate cancer

引用

Asian Journal of Andrology 2016年第4期18卷 543-548页

作者： Jonathan Shoag christopher e Barbieri Department of Urology NewYork-Presbyterian Hospital Weill Cornell Medical College New York USA Sandra and edward Meyer Cancer Center Weill Cornell Medica College New York USA.

Prostate cancer is a clinically heterogeneous disease, with some men having indolent disease that can safely be observed, while others have aggressive, lethal disease. Over the past decade, researchers have begun to unravel some of the genomic heterogeneity that contributes to these varying clinical phenotypes. Distinct molecular sub-classes of prostate cancer have been identified, and the uniqueness of these sub-classes has been leveraged to predict clinical outcomes, design novel biomarkers for prostate cancer diagnosis, and develop novel therapeutics. Recent work has also elucidated the temporal and spatial heterogeneity of prostate cancer, helping us understand disease pathogenesis, response to therapy, and progression. New genomic techniques have provided us with a window into the remarkable clinical and genomic heterogeneity of prostate cancer, and this new perspective will increasingly impact patient care.

关键词： cell biology eRG genomics molecular heterogeneity prostate cancer sequencing serine peptidase inhibitor, Kazaltype 1 SPOP tumor profiling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Small duct primary sclerosing cholangitis: A discrete variant or a bridge to large duct disease, a practical review

引用

World Journal of Hepatology 2022年第3期14卷 495-503页

作者： christopher M Nguyen Kevin T kline Heather L Stevenson Kashif Khan Sreeram Parupudi Department of Internal Medicine The University of Texas Medical BranchGalvestonTX 77555United States Department of Gastroenterology and Hepatology The University of Texas Medical BranchGalvestonTX 77555United States Department of Pathology University of Texas Medical BranchGalvestonTX 77555United States

The natural history,associations with inflammatory bowel disease(IBD),and long-term outcomes of large duct primary sclerosing cholangitis(ldPSC)have been well *** duct primary sclerosing cholangitis(sdPSC)is a much less common and relatively more benign *** natural history of sdPSC has been difficult to characterize given the limited number of studies in the literature especially with regards to the subset of patients who progress to large duct *** has been unclear whether sdPSC represented a subset of ldPSC,an earlier staging of ldPSC,or a completely separate and distinct entity of its *** associations between sdPSC and IBD have been established with suspicion that concurrent sdPSC-IBD may be a key prognostic factor in determining which patients are at risk of progression to *** is known regarding the discrete circumstances that predisposes some patients with sdPSC to progress to *** has been suspected that progression to large biliary duct involvement subjects this subset of patients to potentially developing lifethreatening *** the authors conducted a thorough review of the published sdPSC literature using Pubmed searches and cross-referencing to compile all accessible studies regarding cohorts of sdPSC patients in order better characterize the subset of sdPSC patients who progress to ldPSC and the associated outcomes.

关键词： Small duct primary sclerosing cholangitis Inflammatory bowel disease Progression Primary sclerosing cholangitis Outcomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ethnopharmacology,phytochemistry,and biological activities of Cymbopogon citratus(DC.) Stapf extracts

引用

Chinese Journal of Natural Medicines 2015年第5期13卷 321-337页

作者： christopher e ekpenyong ernest Akpan Azah Nyoh Department of Physiology Faculty of Basic Medical SciencesUniversity of Uyo Department of Physiology Faculty of Basic Medical SciencesUniversity of Calabar

Cymbopogon citratus is a widely distributed perennial herb belonging to the Poaceae family and has been extensively consumed for its medicinal,cosmetic,and nutritional effects for centuries.A large number of reports have been published describing the pharmacological,biological,and therapeutic actions of this *** this review,we summarized the literatures on related studies(up to January,2014) that highlighted the pharmacologic and biological effects of the major phytochemicals isolated from *** extracts and its essential *** components of the essential oils found in *** have a similar pharmacokinetic properties,including absorption,distribution,metabolism,and *** are quickly absorbed following oral,pulmonary,and dermal *** on the published reports,it can also be inferred that,after absorption from the small intestine,some phytochemicals in *** can undergo oxidation,glucuronidation,sulfation,and/or *** is through urine,feces and/or expired *** biotransformation reactions of *** bioactive constituents are essential for its relatively safe consumption and therapeutic *** data available so far warrant further studies evaluating *** *** pharmacokinetic data in humans would be critical for a better understanding of the the systemic handling of ***.

关键词： Cymbopogon citratus stapf Phytochemistry Pharmacological effects

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The evolution of phenotypic plasticity in fish swimming

引用

Current Zoology 2016年第5期62卷 475-488页

作者： christopher e. OUFIeRO Katrina R. WHITLOW Department of Biological Sciences Towson University Towson MD 21252 USA

Fish have a remarkable amount of variation in their swimming performance, from within species dif- ferences to diversity among major taxonomic groups. Fish swimming is a complex, integrative phenotype and has the ability to plastically respond to a myriad of environmental changes. The plasticity of fish swimming has been observed on whole-organismal traits such as burst speed or critical swimming speed, as well as underlying phenotypes such as muscle fiber types, kinematics, cardiovascular system, and neuronal processes. Whether the plastic responses of fish swimming are beneficial seems to depend on the environmental variable that is changing. For example, because of the effects of temperature on biochemical processes, alterations of fish swimming in response to tem- perature do not seem to be beneficial. In contrast, changes in fish swimming in response to variation in flow may benefit the fish to maintain position in the water column. In this paper, we examine how this plasticity in fish swimming might evolve, focusing on environmental variables that have received the most attention： temperature, habitat, dissolved oxygen, and carbon dioxide variation. Using examples from previous research, we highlight many of the ways fish swimming can plastic- ally respond to environmental variation and discuss potential avenues of future research aimed at understanding how plasticity of fish swimming might evolve. We consider the direct and indirect ef- fects of environmental variation on swimming performance, including changes in swimming kine- matics and suborganismal traits thought to predict swimming performance. We also discuss the role of the evolution of plasticity in shaping macroevolutionary patterns of diversity in fish swimming.

关键词： environmental variation evolution fish phenotypic plasticity swimming kinematics swimming performance.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Understanding development and ripening of fruit crops in an‘omics’ era

引用

Horticulture Research 2014年第1期1卷 157-166页

作者： Nigel e Gapper James J Giovannoni christopher B Watkins Department of Horticulture Cornell UniversityIthacaNY 14853USA Boyce Thompson Institute for Plant Research Cornell UniversityIthacaNY 14853USA Plant Soiland Nutrition LaboratoryUS Department of Agriculture/Agriculture Research ServiceIthacaNY 14853USA

Next generation sequencing has revolutionized plant *** only has our understanding of plant metabolism advanced using model systems and modern chromatography,but application of‘omics’-based technology has been widely extended to non-model systems as costs have plummeted and efficiency *** a result,important fundamental questions relating to important horticultural crops are being answered,and novel approaches with application to industry are in *** we review recent research advances on development and ripening of fruit crops,how next generation sequencing approaches are driving this advance and the emerging future landscape.

关键词： crops driving metabolism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ABCD^(2) risk score does not predict the presence of cerebral microemboli in patients with hyper-acute symptomatic critical carotid artery stenosis

引用

Stroke & Vascular Neurology 2017年第2期2卷 41-46页

作者： Mahmud Saedon Charles e Hutchinson christopher H e Imray Donald R J Singer Warwick Medical School University of WarwickCoventryUK University Hospitals Coventry Warwickshire NHS Trust CoventryUK Fellowship of Postgraduate Medicine LondonUK Yale School of Medicine New HavenConnecticutUSA

Introduction:ABCD^(2) risk score and cerebral microemboli detected by transcranial Doppler(TCD)have been separately shown to the predict risk of recurrent acute *** studied whether ABCD2 risk score predicts cerebral microemboli in patients with hyper-acute symptomatic carotid artery *** and methods:We studied 206 patients presenting within 2 weeks of transient ischaemic attack or minor stroke and found to have critical carotid artery stenosis(≥50% ).86 patients(age 70±1(SeM:years),58 men,83 Caucasian)had evidence of microemboli;72(84% )of these underwent carotid endarterectomy(CeA).120 patients(age 72±1 years,91 men,113 Caucasian)did not have microemboli detected;102(85% )of these underwent *** were analysed using X2 and Mann–Whitney U tests and receiver operating characteristic(ROC)***:140/206(68% :95% CI 61.63 to 74.37)patients with hyper-acute symptomatic critical carotid stenosis had an ABCD2 risk score≥*** was no significant difference in the NICe red flag criterion for early assessment(ABCD^(2) risk score≥4)for patients with cerebral microemboli versus those without microemboli(59/86 vs 81/120 patients:OR 1.05 ABCD2 risk score≥4(95% CI 0.58 to 1.90,p=0.867)).The ABCD2 risk score wasembolising patients and in 39 of 120(31% :95% CI 23 to 39)without cerebral *** adjusting for pre-neurological event antiplatelet treatment(APT),area under the curve(AUC)of ROC for ABCD2 risk score showed no prediction of cerebral microemboli(no pre-event APT,n=57:AUC 0.45(95% CI 0.29 to 0.60,p=0.531);preevent APT,n=147:AUC 0.51(95% CI 0.42 to 0.60,p=0.804)).Conclusions:The ABCD2 score did not predict the presence of cerebral microemboli or carotid disease in over one-quarter of patients with symptomatic critical carotid artery *** the basis of NICe guidelines(refer early if ABCD2≥4),assessment of high stroke risk based on ABCD2 scoring may lead to inappropriate delay in urgent treat

关键词： patients cerebral emboli

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Beyond the RPA and GW methods with adiabatic xc-kernels for accurate ground state and quasiparticle energies

引用

npj Computational Materials 2019年第1期5卷 202-224页

作者： Thomas Olsen christopher e.Patrick Jefferson e.Bates Adrienn Ruzsinszky Kristian S.Thygesen Computational Atomic-Scale Materials Design(CAMD) Department of PhysicsTechnical University of DenmarkKongens LyngbyDenmark Department of Physics University of WarwickCoventry CV47ALUK A.R.Smith Department of Chemistry and Fermentation Sciences Appalachian State UniversityBooneNC 28607USA Department of Physics Temple UniversityPhiladelphiaPA 19122USA Center for Nanostructured Graphene(CNG) Department of PhysicsTechnical University of DenmarkKongens LyngbyDenmark

We review the theory and application of adiabatic exchange–correlation(xc)-kernels for ab initio calculations of ground state energies and quasiparticle excitations within the frameworks of the adiabatic connection fluctuation dissipation theorem and Hedin’s equations,*** different xc-kernels,which are all rooted in the homogeneous electron gas,are introduced but hereafter we focus on the specific class of renormalized adiabatic kernels,in particular the rALDA and *** kernels drastically improve the description of short-range correlations as compared to the random phase approximation(RPA),resulting in significantly better correlation *** effect greatly reduces the reliance on error cancellations,which is essential in RPA,and systematically improves covalent bond energies while preserving the good performance of the RPA for dispersive *** quasiparticle energies,the xc-kernels account for vertex corrections that are missing in the GW *** this context,we show that the short-range correlations mainly correct the absolute band positions while the band gap is less affected in agreement with the known good performance of GW for the *** renormalized xc-kernels offer a rigorous extension of the RPA and GW methods with clear improvements in terms of accuracy at little extra computational cost.

关键词： adiabatic kernels quasi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：