检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

了解你的法律义务使策划更容易

中国会展 2024年第8期 40-47页

作者： christine Loomis 不详

法律问题是每一次会议活动重要的一部分——然而,在处理这些法律问题时,没有一个放之四海而皆准的方案。Maritz副总裁兼副总法律顾问吉尔•布拉德(Jill Blood)说:“策划会议所涉及的法律问题和会议本身一样多种多样。对于小型、低风险的... 详细信息

法律问题是每一次会议活动重要的一部分——然而,在处理这些法律问题时,没有一个放之四海而皆准的方案。Maritz副总裁兼副总法律顾问吉尔•布拉德(Jill Blood)说:“策划会议所涉及的法律问题和会议本身一样多种多样。对于小型、低风险的会议来说,法律问题通常很直接,主要集中在合同上。对于更大的复杂活动,风险管理可能更加复杂。”

关键词：法律义务总法律顾问风险管理布拉德低风险策划合同会议

维普期刊数据库博看期刊

Amyloid-beta and tau protein beyond Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第6期19卷 1262-1276页

作者： Morteza Abyadeh Vivek Gupta Joao A.Paulo Arezoo Gohari Mahmoudabad Sina Shadfar Shahab Mirshahvaladi Veer Gupta christine T.O.Nguyen David I.Finkelstein Yuyi You Paul A.Haynes Ghasem H.Salekdeh Stuart L.Graham Mehdi Mirzaei ProGene Technologies Pty Ltd. SydneyNSWAustralia Department of Clinical Medicine Faculty of MedicineHealth and Human SciencesMacquarie Medical SchoolMacquarie UniversityMacquarie ParkNorth RydeSydneyNSWAustralia Department of Cell Biology Harvard Medical SchoolBostonMAUSA School of Medicine Deakin UniversityGeelongVICAustralia Department of Optometry and Vision Sciences School of Health SciencesFaculty of Medicine Dentistry and Health SciencesUniversity of MelbourneParkvilleVICAustralia The Florey Institute of Neuroscience and Mental Health The University of MelbourneParkvilleVICAustralia School of Natural Sciences Macquarie UniversityMacquarie ParkNSWAustralia

The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to play key roles in Alzheimer's disease pathogenesis and are considered the main pathological hallmarks of this devastating ***,these two proteins are produced and expressed within the normal human ***,under pathological conditions,abnormal expression,posttranslational modifications,conformational changes,and truncation can make these proteins prone to aggregation,triggering specific disease-related *** studies have indicated associations between aberrant behavior of amyloid-beta and tau proteins and various neurological diseases,such as Alzheimer's disease,Parkinson's disease,and amyotrophic lateral sclerosis,as well as retinal neurodegenerative diseases like Glaucoma and age-related macular ***,these proteins have been linked to cardiovascular disease,cancer,traumatic brain injury,and diabetes,which are all leading causes of morbidity and *** this comprehensive review,we provide an overview of the connections between amyloid-beta and tau proteins and a spectrum of disorders.

关键词： amyloid-beta cancer cardiovascular diseases diabetes neurodegeneration Tau traumatic brain injury

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

银行绿色转型之困

商业周刊（中文版） 2024年第5期 29-31页

作者： christine Dobby 王非(译) 不详

2023年11月,加拿大皇家银行(RBC)首席执行官戴夫·麦凯(Dave McKay)从多伦多的家中来到渥太华,接受加拿大皇家地理学会(Royal Canadian Geographical Society)颁发的奖章。在加拿大战争博物馆举行的仪式上,地理学会对他大加称赞,表彰他... 详细信息

2023年11月,加拿大皇家银行(RBC)首席执行官戴夫·麦凯(Dave McKay)从多伦多的家中来到渥太华,接受加拿大皇家地理学会(Royal Canadian Geographical Society)颁发的奖章。在加拿大战争博物馆举行的仪式上,地理学会对他大加称赞,表彰他的公司为环保事业所做出的贡献。

关键词：加拿大皇家银行绿色转型首席执行官皇家地理学会环保事业多伦多

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

混动飞机飞向蓝天

科技纵览 2024年第2期 30-36,4页

作者： Amy Jankovsky christine Andrews Bill Rogers 不详

NASA、通用电气航空公司和波音公司正在合作开发一款混合动力客机。商业航空联结了现代世界。国际民用航空组织(ICAO)的数据表明,在全球新冠疫情之前,每天平均有1200万人乘坐约10万次商业航班。这些数字现在已经大幅回升:预计2023年行... 详细信息

NASA、通用电气航空公司和波音公司正在合作开发一款混合动力客机。商业航空联结了现代世界。国际民用航空组织(ICAO)的数据表明,在全球新冠疫情之前,每天平均有1200万人乘坐约10万次商业航班。这些数字现在已经大幅回升:预计2023年行业收入将达到8030亿美元,比2022年增长9.7%,接近2019年疫情前的峰值。

关键词：商业航空混合动力通用电气合作开发数据表波音公司航空公司疫情

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

管道清洁机器人的创新应用

现代制造 2024年第1期 27-29页

作者： Andreas Seegen Ellen-christine Rei 不详

地下排水管道需要定期的维护保养,而且最好是在不挖开地面的情况下进行维护保养。为此,Pipetronics公司开发了一种可对地下管道进行维护保养的机器人。这款机器人由Faulhaber公司研发生产的无刷直流电机来驱动机器人车轮运转,驱动机器... 详细信息

地下排水管道需要定期的维护保养,而且最好是在不挖开地面的情况下进行维护保养。为此,Pipetronics公司开发了一种可对地下管道进行维护保养的机器人。这款机器人由Faulhaber公司研发生产的无刷直流电机来驱动机器人车轮运转,驱动机器人的清洁工具完成地下管道的清洁。

关键词：机器人地下管道维护保养 Pipe 无刷直流电机创新应用清洁工具

维普期刊数据库

Evaluating pediatric ureteropelvic junction obstruction:Dynamic magnetic resonance urography vs renal scintigraphy 99mtechnetium mercaptoacetyltriglycine

在线全文

学校读者我要写书评

暂无评论

World Journal of Radiology 2024年第3期16卷 49-57页

作者： Yousuf Al-Shaqsi Matthieu Peycelon Annabel Paye-Jaouen Elisabeth Carricaburu Anca Tanase christine Grapin-Dagorno Alaa El-Ghoneimi Department of Pediatric Surgery Sultan Qaboos University HospitalMuscat 123Oman Service de Chirurgie Viscérale et Urologie Pédiatrique Hôpital Universitaire Robert-DebréAssistance-Publique Hôpitaux de ParisParis 75019France Centre de Références Maladies Rares Malformations Rares des Voies Urinaires(MARVU)Paris 97019France Facultéde Médecine Universitéde ParisParis 75006France Service d’Imagerie Pédiatrique Hôpital Universitaire Robert-DebréAssistance-Publique Hôpitaux de ParisParis 75019France UniversitéParis 13 Sorbonne Paris CitéParis 75013France

BACKGROUND Ureteropelvic junction obstruction(UPJO)is a common congenital urinary tract disorder in *** can be diagnosed as early as in utero due to the presence of hydronephrosis or later in life due to symptomatic *** To evaluate the discrepancy between dynamic contrast-enhanced magnetic resonance urography(dMRU)and scintigraphy 99m-technetium mercaptoacetyltriglycine(MAG-3)for the functional evaluation of *** Between 2016 and 2020,126 patients with UPJO underwent surgery at Robert Debré*** these,83 received a prenatal diagnosis,and 43 were diagnosed during *** of the 126 patients underwent surgery based on the clinical situation and postnatal ultrasound findings without undergoing functional imaging *** renal function was evaluated preoperatively using scintigraphy MAG-3(n=28),dMRU(n=53),or both(n=40).In this study,we included patients who underwent surgery for UPJO and scintigraphy MAG-3+dMRU but excluded those who underwent only scintigraphy MAG-3 or *** patients were divided into groups A(10%discrepancy).We examined the discrepancy in split renal function between the two modalities and investigated the possible risk *** The split renal function between the two kidneys was compared in 40 patients(28 boys and 12 girls)using scintigraphy MAG-3 and *** renal function,as determined using both modalities,showed a difference of10%in 9 *** of the relative renal function using dMRU revealed an excellent correlation coefficient with renal scintigraphy MAG-3 for both *** Our findings demonstrated that dMRU is equivalent to scintigraphy MAG-3 for evaluating split renal function in patients with UPJO.

关键词： Uteropelvic junction obstruction Scintigraphy 99m-technetium mercaptoacetyltriglycine Magnetic resonance imaging Dynamic contrast-enhanced magnetic resonance urography

羧基功能化金纳米团簇的仿生结晶及其近红外磷光性质（英文）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2024年第1期 40-48页

作者：田伟东司为丹 Shana Havenridge 张成凯王芝 christine M.Aikens 佟振合孙頔 School of Chemistry and Chemical Engineering State Key Laboratory of Crystal Materials Shandong University Department of Chemistry Kansas State University

As an interdisciplinary product,water-soluble gold nanoclusters(AuNCs) stabilized by ligands containing carboxyl(-COOH) group have garnered significant attention from synthetic chemists and biologists due to their immense potential for biomedical ***,revealing the crystallographic structures of-COOH-functionalized AuNCs remains a ***,we successfully applied the salting-out method to obtain a series of high-quality single crystals of-COOH-functionalized Au25nanoclusters and revealed their crystallographic ***,K3Au25(2-Hmna)9(mna)6]-(Au25a)protected by 2-mercaptonicotinic acid features an unprecedented tetrameric Au4(SRS)3(SRS,N)2staple motifs surrounding the icosahedral Au13kernel,breaking the traditional perception on the structure of Au25(SR)***25a exhibits a distinct near-infrared emission at 970 nm with long lifetime of 8690 ns,which have been studied by transient absorption spectroscopy and time-dependent density functional *** work compensates for the research gap in the experimental structure of-COOHfunctionalized AuNCs and opens up a new avenue to explore their structure-property correlations.

关键词：

Prehospital transdermal glyceryl trinitrate for ultra- acute ischaemic stroke: data from the RIGHT- 2 randomised sham- controlled ambulance trial

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第1期9卷 38-49,I0035-I0046页

作者： Jason Philip Appleton Lisa J Woodhouse Craig S Anderson Sandeep Ankolekar Lesley Cala Mark Dixon Timothy J England Kailash Krishnan Grant Mair Keith W Muir John Potter Christopher I Price Marc Randall Thompson G Robinson christine Roffe Else C Sandset Jeffrey L Saver Angela Shone Aloysius Niroshan Siriwardena Joanna M Wardlaw Nikola Sprigg Philip M Bath Stroke University Hospitals Birmingham NHS Foundation TrustBirminghamUK Institute of Applied HealthResearch University of Birmingham College of Medical and Dental SciencesBirminghamUK Stroke Trials Unit Mental Health and Clinical NeurosciencesUniversity of NottinghamNottinghamUK Faculty of Medicine The George Institute for Global HealthSydneyNew South WalesAustralia The George Institute China at Peking University Health Science Center BeijingChina Neurology Royal Prince Alfred HospitalSydney Health PartnersSydneyNew South WalesAustralia Department of Neurology King's College Hospital NHS Foundation TrustLondonUK Faculty of Health and Medical Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia East Midlands Ambulance Service NHS Trust NottinghamUK Stroke Queen's Medical CentreNottingham University Hospitals NHS TrustNottinghamUK Centre for Clinical Brain Sciences Dementia Research InstituteUniveristy of EdinburghEdinburghUK Institute of Neurology and Psychology University of GlasgowGlasgowUK Bob Champion Research and Education Building University of East AngliaNorwichUK Institute of Neuroscience Newcastle UniversityNewcastle upon TyneUK Department of Neurology Leeds Teaching Hospitals NHS TrustLeedsUK Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre University of LeicesterLeicesterUK Stroke Research in Stoke Institute for Science and Technology in MedicineKeele UniversityStoke-on TrentUK Department of Neurology Oslo University HospitalOsloNorway Research and Development Norwegian Air Ambulance FoundationOsloNorway Department of Neurology and Comprehensive Stroke Center David Geffen School of MedicineUCLALos AngelesCaliforniaUSA Research and Graduate Services University of NottinghamNottinghamUK Community and Health Research Unit University of LincolnLincolnUK

Background The effect of transdermal glyceryl trinitrate(GTN,a nitrovasodilator)on clinical outcome when administered before hospital admission in suspected stroke patients is ***,we assess the safety and efficacy of GTN in the prespecified subgroup of patients who had an ischaemic stroke within the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2(RIGHT-2).Methods RIGHT-2 was an ambulance-based multicentre sham-controlled blinded-endpoint study with patients randomised within 4hours of *** primary outcome was a shift in scores on the modified Rankin scale(mRS)at day *** outcomes included death;a global analysis(Wei-Lachin test)containing Barthel Index,EuroQol-5D,mRS,telephone interview for cognitive status-modified and Zung depression scale;and neuroimaging-determined‘brain frailty’*** were reported as n(%),mean(SD),median[IQR],adjusted common OR(acOR),mean difference or Mann-Whitney difference(MWD)with 95%*** 597 of 1149(52%)patients had a final diagnosis of ischaemic stroke;age 75(12)years,premorbid mRS>2107(18%),Glasgow Coma Scale 14(2)and time from onset to randomisation 67[45,108]***‘brain frailty’was common:median score 2[2,3](range 0–3).At day 90,GTN did not influence the primary outcome(acOR for increased disability 1.15,95%CI 0.85 to 1.54),death or global analysis(MWD 0.00,95%CI-0.10 to 0.09).In subgroup analyses,there were non-significant interactions suggesting GTN may be associated with more death and dependency in participants randomised within 1hour of symptom onset and in those with more severe *** In patients who had an ischaemic stroke,ultra-acute administration of transdermal GTN in the ambulance did not improve clinical outcomes in a population with more clinical and radiological frailty than seen in previous in-hospital *** IS ALREADY KNOWN ON THIS TOPIC⇒Transdermal glyceryl trinitrate(GTN)was associat-ed with less death and dependency in those w

关键词： Glasgow nitrate random

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

网络安全事件管理和响应指南

中国教育网络 2024年第2期 76-77页

作者： christine Whalley Matt Kenslea Asha Ramachandra Steve Fletcher 董明(译) 不详

确保整个团队了解要采取什么行动,可以对机构如何以及多快地从一个安全事件中恢复产生重要影响事件管理和响应是任何网络安全计划的关键要素。每一个事件都提供了教训和改进的机会,高等教育领导者永远不应该假设类似的事件不会再次发生... 详细信息

确保整个团队了解要采取什么行动,可以对机构如何以及多快地从一个安全事件中恢复产生重要影响事件管理和响应是任何网络安全计划的关键要素。每一个事件都提供了教训和改进的机会,高等教育领导者永远不应该假设类似的事件不会再次发生。本指南涵盖了在事件发生之前、期间和之后应该做些什么,以确保机构通过有效的响应、恢复和持续改进保持更好的弹性。事件发生前制定事件响应计划:制定详细的事件响应计划,概述检测过程、报告和响应安全事件的程序。

关键词：事件响应安全事件检测过程高等教育持续改进关键要素指南网络安全计划

维普期刊数据库