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Coping strategies of Dutch servicemembers after deployment

Military Medical Research 2019年第4期6卷 284-284,289-290,285-288,291页

作者： Loes G.M.de Kruijff Olivia R.M.Moussault Marie-christine j.Plat Rigo Hoencamp Peter van der Wurff Department of Research and Development Military Rehabilitation Center AardenburgDoorn 3941PWThe Netherlands De Hoogstraat Rehabilitation Utrecht 3583TMThe Netherlands Military Mental Healthcare Ministry of DefenseZwolle 8022AEThe Netherlands Force Health Protection Expert Center Force Health ProtectionMinistry of DefenseDoorn 3941PWThe Netherlands Department of Surgery Leiden University Medical Center2333ZALeidenThe Netherlands Department of Surgery Alrijne Medical CenterLeiderdorp 2334CKThe Netherlands Department of Surgery Central Military Hospital Ministry of DefenseUtrecht 3584EZThe Netherlands Institute of Human Movement Studies HU University of Applied Sciences UtrechtUtrecht 3584CSThe Netherlands Department of Research and Development Military Rehabilitation Center AardenburgP.O.box 185Doorn 3940ADThe Netherlands

Background:This study examines the relationship between coping strategies and symptoms of anxiety or depression among Dutch servicemembers deployed to ***:Coping strategies were assessed in 33 battlefield casualties(BCs)and the control group(CTRLs)of 33 uninjured servicemembers from the same combat units using the Cognitive Emotion Regulation Questionnaire.A factor analysis was performed,and two clusters of coping strategies were derived,namely,adaptive and maladaptive *** of anxiety and depression were evaluated using the depression and anxiety subscales of the Symptom *** between coping and symptoms of anxiety and between coping and symptoms of depression were calculated,and a logistic regression was ***:A moderate correlation was observed between maladaptive coping and symptoms of anxiety in the BC group(r=0.42)and among the CTRLs(r=0.56).A moderate correlation was observed between maladaptive coping and symptoms of depression in both groups(r=0.55).The statistical analysis for the total sample(BCs and CTRLs)demonstrated no association between coping and symptoms of anxiety or ***:A correlation but no association was observed between maladaptive coping and mental health disorders in deployed Dutch *** research should focus on constructing cluster profiles of coping strategies and associating them with mental health outcomes and reintegration into society.

关键词： Military personnel Mental health Coping behavior Afghanistan Rehabilitation

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Microbiology : an introduction / Gerard j. Tortora, Berdell R. Funke, christine L. Case. 6th ed.

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1998年

作者： Gerard j. Tortora Berdell R. Funke christine L. Case.

Includes index.

ISBN: (纸本)0805385355

Includes index.

关键词： Microbiology.

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成人肝移植：非专业医生需要知道什么

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英国医学杂志中文版 2009年第5期12卷 292-298页

作者： G M Hirschfield P Gibbs W j H griffiths 李涛(译) 冷希圣(校) Liver Centre Toronto Western Hospital/ University of Toronto Ttronto ON Canada M.ST 2S8 Hepatology and Liver Transplant Service Addenbrooke's Hospital Cambfige UK 北京大学人民医院肝胆外科

英国目前约有6000例存活的肝移植受者，每年约有600例肝病患者接受肝移植手术。移植后的患者数量在不断增长，因为每年接受肝移植的600例患者中近550人在移植后1年仍然存活，至少300人在移植后20年依然存活。我们的这篇综述是给非肝移... 详细信息

英国目前约有6000例存活的肝移植受者，每年约有600例肝病患者接受肝移植手术。移植后的患者数量在不断增长，因为每年接受肝移植的600例患者中近550人在移植后1年仍然存活，至少300人在移植后20年依然存活。我们的这篇综述是给非肝移植专业的医生讲解肝移植，重点是成人肝移植。

关键词：肝移植受者医生成人肝移植手术移植后肝病患者患者数量存活

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Polycomb response element-binding sites in the MDR of CLL: Potential tumor suppressor regulation

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Advances in Bioscience and Biotechnology 2013年第1期4卷 129-135页

作者： christine E. Cutucache javeed Iqbal Philip j. Bierman Robert Gregory Bociek Dennis D. Weisenburger Shantaram S. joshi Department of Biology University of Nebraska at Omaha Omaha USA Department of Genetics Cell Biology and Anatomy University of Nebraska Medical Center Omaha USA Department of Internal Medicine Oncology/Hematology University of Nebraska Medical Center Omaha USA Department of Pathology and Microbiology University of Nebraska Medical Center Omaha USA

Chronic lymphocytic leukemia [CLL] is the most common adult leukemia and is heterogeneous in clinical presentation. CLL cases present with various chromosomal aberrations, including 11q23, 14q32, 17p, and trisomy 12, with the most common abnormality being deletion of 13q14 [1]. Although monoallelic deletion of 13q14 is common, there is a subset of patients who have complete nullisomy at 13q14, a locus that has been hypothesized to contribute to CLL pa thogenesis [2] due to loss of tumor suppressors [DLEU and miR-15a/16-1]. We hypothesized that deletion of both copies of 13q14 would lead to uncontrollable proliferation of CLL cells and a poor prognosis. We examined our 13q14 nullisomy for survival, treatment-free survival, lymphocyte doubling time, and the presence of lymphadenopathy. Furthermore, we compared the gene expression profiles between patients with 13q14 monosomy, nullisomy, or normal karyotype. Our results suggest that patients with 13q nullisomy have a higher incidence of bulky lymphadenopathy [16.6% compared to 10% of monosomy patients], a higher frequency of lymphocyte doubling time [27.7% compared to 7.4% of monosomy patients], and a higher rate of needing treatment [50% compared to 18.5% of monosomy patients]. We observed deletion of DLEU1 and HTR2A, consistent with a gene dosage effect, and observed PRE-binding sites on DLEU1. Patients with homozygous deletion of 13q14 had a worse prognosis compared to heterozygotes. Lastly, the DLEU1 locus is a possible “second hit” loss for CLL progression.

关键词： Chronic Lymphocytic Leukemia Gene Expression 13q14 Nullisomy DLEU Tolerogenic

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Microbiology An Introduction Gerard j. Tortora, Berdell R. Funke, christine L. Case 7th ed.

Microbiology An Introduction Gerard J. Tortora, Berdell R. F...

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2001年

作者： Gerard j. Tortora Berdell R. Funke christine L. Case

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Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats

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World journal of Gastroenterology 2006年第41期12卷 6639-6645页

作者： Frédéric Moal Nary Veal Eric Vuillemin Eric Barrière jianhua Wang Lionel Fizanne Frédéric Oberti Olivier Douay Yves Gallois Dominique Bonnefont-Rousselot Marie christine Rousselet Paul Calès Laboratoire HIFIH UPRES 3859 Université Angers France Laboratoire de Biochimie Université Angers France INSERM U481 Hopital Beaujon Clichy France Laboratoire de Biochimie Hopital de 1a Salpêtrière Paris France

AIM: To assess whether a liver specific nitric oxide (NO) donor (V-PYRRO/NO) would prevent the development of portal hypertension and liver fibrosis in rats with bile duct ligation (BDL). METHODS: Treatment (placebo or V-PYRRO/NO 0.53 μmol/kg per hour) was administered i.v. to rats 2 d before BDL (D-2) and maintained until the day of hemodynamic measurement (D26). Intra-hepatic NO level was estimated by measuring liver cGMP level. Effects of V-PYRRO/NO on liver fibrosis and lipid peroxidation were also assessed. RESULTS: Compared to placebo treatment, V-PYRRO/ NO improved splanchnic hemodynamics in BDL rats: portal pressure was significantly reduced by 27% (P < 0.0001) and collateral circulation development was almost completely blocked (splenorenal shunt blood flow by 74%, P = 0.007). Moreover, V-PYRRO/NO significantly prevented liver fibrosis development in BDL rats (by 30% in hepatic hydroxyproline content and 31% in the area of fibrosis, P < 0.0001 respectively), this effect being probably due to a decrease in lipid peroxidation by 44% in the hepatic malondialdehyde level (P = 0.007). Interestingly, we observed a significant and expected increase in liver cGMP, without any systemic hemodynamic effects (mean arterial pressure, vascular systemic resistance and cardiac output) in both sham- operated and BDL rats treated with V-PYRRO/NO. This result is in accordance with studies on V-PYRRO/NO metabolism showing a specific release of NO in the *** in BDL rats improved liver fibrosis and splanchnic hemodynamics without any noxious systemic hemo- dynamic effects.

关键词： Nitric oxide Portal hypertension Liver fibrosis Hemodynamics Rats

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A Versatile Phenotyping System and Analytics Platform Reveals Diverse Temporal Responses to Water Availability in Setaria

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Molecular Plant 2015年第10期8卷 1520-1535页

作者： Noah Fahlgren Maximilian Feldman Malia A. Gehan Melinda S. Wilson christine Shyu Douglas W. Bryant Steven T. Hill Colton j. McEntee ankalpi N. Warnasooriya Indrajit Kumar Tracy Ficor Stephanie Turnipseed Kerrigan B. Gilbert Thomas P. Brutnell james C. Carrington Todd C. Mockler Ivan Baxter Donald Danforth Plant Science Center St. Louis MO 63132 USA USDA-ARS Donald Danforth Plant Science Center St. Louis MO 63132 USA These authors contributed equally to this article.

Phenotyping has become the rate-limiting step in using large-scale genomic data to understand and improve agricultural crops. Here, the Bellwether Phenotyping Platform for controlled-environment plant growth and automated multimodal phenotyping is described. The system has capacity for 1140 plants, which pass daily through stations to record fluorescence, near-infrared, and visible images. Plant Computer Vision （PlantCV） was developed as open-source, hardware platform-independent software for quantitative image analysis. In a 4-week experiment, wild Setaria viridis and domesticated Setaria italica had fundamentally different temporal responses to water availability. While both lines produced similar levels of biomass under limited water conditions, Setaria viridis maintained the same water-use efficiency under water replete conditions, while Setaria italica shifted to less efficient growth. Overall, the Bellwether Phenotyping Platform and PlantCV software detected significant effects of genotype and environment on height, biomass, water-use efficiency, color, plant architecture, and tissue water status traits. All -79 000 images acquired during the course of the experiment are publicly available.

关键词： abiotic/environmental stress water relations bioinformatics development phenotyping

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The exploitation of epichloae endophytes for agricultural benefit

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Fungal Diversity 2013年第3期60卷 171-188页

作者： Linda j.johnson Anouck C.M.de Bonth Lyn R.Briggs john R.Caradus Sarah C.Finch Damien j.Fleetwood Lester R.Fletcher David E.Hume Richard D.johnson Alison j.Popay Brian A.Tapper Wayne R.Simpson christine R.Voisey Stuart D.Card AgResearch Ltd Grasslands Research CentreTennent DrivePalmerston North 4442New Zealand AgResearch Ltd Ruakura Research CentreEast StreetHamilton 3214New Zealand AgResearch Ltd Lincoln Research CentreCorner Springs Road and Gerald StreetLincoln 8140New Zealand AgResearch Laboratory of Structural Biology School of Biological SciencesUniversity of Auckland3a Symonds StreetAuckland 1142New Zealand Grasslanz Technology Ltd Tennent DrivePalmerston North 4474New Zealand

Epichloae endophytes of family Clavicipitaceae(comprising genera Epichloëand Neotyphodium)are fungal symbionts of Pooideae *** associations formed,range from mutually beneficial to antagonistic and the nature of this relationship is dependent upon the importance of vertical(via host seeds)versus horizontal(ascospore mediated)transmission of the *** endophytes can enhance their hosts’survival through protection from abiotic and biotic stresses and can thus be utilized in an agricultural ***-safe grass-endophyte associations that confer bio-protective properties for increased pasture persistence and productivity have been developed and *** of the crucial drivers underpinning the selection of epichloae strains for commercial development is endophyte derived *** potential of next generation endophytes is determined by testing a number of attributes such as agronomic fitness,animal and food safety as well as compatibility with host plants of *** research supports these activities by focusing on elucidating mechanisms of compatibility between host and fungal symbiont,as well as investigating other molecular drivers of symbiosis such as siderophore mediated iron-uptake,fungal signalling,fungal growth in host plants and fungal secondary *** review weaves together the different strands of multidisciplinary research aimed at ultimately exploiting epichloae endophytes for increased pasture performance.

关键词： Epichloë Neotyphodium Pooideae Symbiosis Secondary metabolite Toxicology

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第2届搜索引擎评测

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电子与电脑 1997年第10期4卷 84-91页

作者： Matthew j.Lake christine Wendin Lulit Bezuayehu 李海

AltaVista、Excite、HotBot和Infoseek四个搜索引擎巨头在这里会面,另外,还有专家们的搜索秘诀。

关键词： Web Internet网搜索引擎评测

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塑料上的离子镀金属

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真空 1981年第2期 52-54页

作者： K.jones ,A.j.griffiths　 ,E.W.Williams ,王隽品

本文对于塑料基片离子镀金属作了初步研究。采用了四种塑料衬底：聚醚砜、聚丙稀、聚酰亚铵和聚脂．详细研究了聚醚砜，并且比较了离子镀和蒸发镀的划痕试验和反射率的测量。在离子镀Ａｕ、Ｃｕ和Ａｌ膜上获得了优良的附着力。就聚醚砜... 详细信息

本文对于塑料基片离子镀金属作了初步研究。采用了四种塑料衬底：聚醚砜、聚丙稀、聚酰亚铵和聚脂．详细研究了聚醚砜，并且比较了离子镀和蒸发镀的划痕试验和反射率的测量。在离子镀Ａｕ、Ｃｕ和Ａｌ膜上获得了优良的附着力。就聚醚砜离子镀铜来说，制造可挠性的印刷线路板是毫无困难的。这就指出了在塑料上离子镀金属薄膜的可能性。

关键词：离子镀化学镀塑料基片塑料聚合物金属金属材料

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