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Artificial light at night(ALAN) pollution alters bat lunar chronobiology:insights from broad-scale long-term acoustic monitoring

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Ecological Processes 2024年第1期13卷 176-187页

作者： Han Li Pauline Allen Saige Boris Samantha Lagrama Jade Lyons christina Mills Pauline Moussi Casey Nichols Carter Tacosik Mc Kenzie Tsaousis Nyzaya Livingston Wilson John F.Grider Kevin A.Parker Matina C.Kalcounis-Rueppell Department of Biology University of Nebraska Omaha Department of Biology University of North Carolina Greensboro Colorado Parks and Wild-life Parker Ecology LLC Department of Biological Sciences University of Alberta

Background The timing of behavior and habitat use of nocturnal animals can be influenced by the lunar cycle in nature. The prevalence of artificial light at night(ALAN) has been recognized as a source of environmental pol-lution. The interaction between ALAN and the lunar cycle on bat behavior is important for understanding anthro-pogenic effects on bats. We utilized a decade(2012–2022) of acoustic monitoring data collected in North Carolina, United States, to investigate the relationship between bat activity, lunar cycle, and light pollution. We examined whether the amount of lunar illumination affected species-specific nightly activity and whether hourly bat activity patterns varied between nights with different moon phases. We further investigated if the relationship between bat activity and the lunar cycle might be altered by light *** We found that seven bat species showed activity variation across nights in relation to the amount of moon illumination when ALAN was absent. In general, bats were less active on full moon nights compared to new moon nights. Light pollution interacted with the bat–lunar relationship in five of the seven species, masking the effect of the lunar cycle. We identified delayed bat activity patterns on nights with a full or waxing moon in seven species, and light pollution altered that pattern in four species. Overall, ALAN was associated with decreased bat activity inde-pendent of lunar cycle *** Our study demonstrated that at a broad spatial scale, ALAN negatively affected many North American temperate bat species and altered their lunar chronobiology. As light pollution is spreading to historically dark areas and habitats, ALAN might couple with other threats, such as the white-nose syndrome or climate change, to cause cascading damage in the environment that depends on ecosystem services such as pest control provided by bats. We argue that further research and conservation actions are needed to mitigate

关键词： Artificial light at night ALAN Bats Chiroptera Chronobiology Light pollution Lunar cycle Moonlight

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Psychiatric Sequelae of Chronic Pruritic Dermatoses

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Open Journal of Medical Psychology 2024年第2期13卷 25-38页

作者： Kelly Frasier Vivian Li Kathleen Click christina Dudzik Michelle Sobotka Evadne Rodriguez Karina Stech Nuvance Health/Vassar Brothers Medical Center Poughkeepsie NY USA School of Osteopathic Medicine Kansas City University Kansas City MO USA Touro College of Osteopathic Medicine Middleton Campus Middletown NY USA Abrazo Health Network Goodyear AZ USA School of Medicine University of Missouri-Columbia Columbia MO USA Lewis Katz School of Medicine at Temple University Philadelphia PA USA

This comprehensive review investigates the significant psychological impact and profound psychological comorbidities found in individuals suffering from chronic pruritic dermatoses, including atopic dermatitis, chronic urticaria, and prurigo nodularis. Highlighting the complex, reciprocal relationship between pruritus and psychiatric conditions such as depression, anxiety, and sleep disturbances, this paper elucidates the comprehensive impact of dermatological disorders on the skin in addition to the far-reaching effects on an individual’s psychological well-being. By evaluating the efficacy of integrated psychodermatological interventions, including cognitive behavioral therapy, mindfulness practices, pharmacological treatments, and innovative telepsychiatry and digital health solutions, this review aims to lay the foundation for a more holistic approach to treatment of concurrent dermatological and psychiatric conditions. Future research endeavors should delve deeper into the mechanistic foundation of the pruritus-psychiatry interface, the refinement of tailored treatment strategies, and the evaluation of long-term patient outcomes. In doing so, this review seeks to contribute to the optimization of patient care and well-being, underscoring the pivotal role of addressing both dermatological and psychological needs in achieving comprehensive health outcomes.

关键词： Psychodermatology Chronic Pruritic Dermatoses Psychological Comorbidities Integrated Interventions Pruritus-Psychiatry Interface

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Early anticoagulation in patients with stroke and atrial fibrillation is associated with fewer ischaemic lesions at 1 month: the ATTUNE study

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Stroke & Vascular Neurology 2024年第1期9卷 30-37,I0034页

作者： Angelos Sharobeam Longting Lin christina Lam Carlos Garcia-Esperon Yash Gawarikar Ronak Patel Matthew Lee-Archer Andrew Wong Michael Roizman Amanda Gilligan Andrew Lee Kee Meng Tan Susan Day Christopher Levi Stephen M Davis Mark Parsons Bernard Yan Melbourne Brain Centre at Royal Melbourne Hospital ParkvilleVictoriaAustralia University of New South Wales South Western Sydney Clinical School LiverpoolNew South WalesAustralia Department of Neurology John Hunter HospitalNewcastleNew South WalesAustralia Department of Neurology Calvary Public HospitalCanberraAustralian Capital TerritoryAustralia Department of Neurology Northern Hospital EppingEppingVictoriaAustralia Department of Neurology Royal Brisbane and Women's HospitalHerstonQueenslandAustralia The University of Queensland School of Medicine HerstonQueenslandAustralia Neurosciences Clinical Institute Epworth HealthcareRichmondVirginiaAustralia Department of Neurology Austin HealthUniversity of MelbourneHeidelbergVictoriaAustralia Flinders University College of Medicine and Public Health AdelaideSouth AustraliaAustralia Department of Neurology Gold Coast University HospitalSouthportQueenslandAustralia The University of Sydney Northern Clinical School St LeonardsNew South WalesAustralia Department of Neurology and Neurophysiology Liverpool HospitalLiverpoolNew South WalesAustralia

Background The optimal time to commence anticoagulation in patients with atrial fibrillation(AF)after ischaemic stroke or transient ischaemic attack(TIA)is unclear,with guidelines differing in recommendations.A limitation of previous studies is the focus on clinically overt stroke,rather than radiologically obvious diffusion-weighted imaging ischaemic *** aimed to quantify silent ischaemic lesions and haemorrhages on MRI at 1month in patients commenced on early(5mL,regardless of anticoagulation *** Commencing anticoagulation<4days after stroke or TIA is associated with fewer ischaemic lesions at 1month in AF *** is no increased rate of haemorrhage with early *** results suggest that early anticoagulation after mild-to-moderate acute ischaemic stroke associated w

关键词： patients lesions ischaemic

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Upper extremity vascular injuries:Etiology,management and outcome

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World Journal of Critical Care Medicine 2024年第2期13卷 159-167页

作者： Nikolaos Stefanou Theodoros Mylonas Fragkiskos A Angelis christina Arnaoutoglou Sokratis E Varitimidis Zoe H Dailiana Department of Orthopaedic Surgery Faculty of MedicineSchool of Health SciencesUniversity of ThessalyUniversity Hospital of LarissaLarissa 41500Greece Department of Hand Upper Extremity and MicrosurgeryIASO ThessaliasLarissa 41500Greece

BACKGROUND Vascular injuries of the upper extremities are considered relatively rare injuries affecting mostly the young *** often are complex injuries accompanied by other musculoskeletal trauma or trauma in other anatomic *** management is challenging since they can lead to disabilities with major socioeconomic *** To analyze data about the mechanism of injury,the management algorithm and functional outcomes of vascular injuries of the upper *** One hundred and fifteen patients(96 males and 19 females)with arterial injuries of the upper extremity treated in a tertiary trauma center from January 2003 to December 2022 was *** patients’age was 33.7 years and the mean follow up time was 7.4 *** with Mangled Extremity Severity Score≥7 and Injury Severity Score≥20,previous upper limb surgery or major trauma and any neuromuscular or psychiatric disease were excluded,from the *** A penetrating trauma was the most common cause of *** radial artery was the artery injured in most of the cases(37.4%)followed by the ulnar(29.5%),the brachial(12.1%)and the axillary(6%).A simultaneous injury of both of the forearm’s arteries was in 15.6%of the *** 93%of the cases there were other concomitant musculoskeletal injuries of the *** lacerations were the most common,followed by nerve *** postoperative functional scores(full Disabilities of the Arm,Shoulder,and Hand and VAS)had very satisfactory *** Although vascular injuries of the upper extremity are rare,they may occur in the context of major combined musculoskeletal *** a multidisciplinary approach is essential to optimize outcome,the ability of trained hand surgeons to repair all injuries in combined vascular and musculoskeletal upper extremity trauma,excluding isolated vascular injuries,ensures shorter operative times and better functional outcomes.

关键词： Upper extremity Vascular injuries Complex injuries Musculoskeletal trauma Mangled extremity

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Aging impairs the osteocytic regulation of collagen integrity and bone quality

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Bone Research 2024年第1期12卷 78-94页

作者： Charles A.Schurman Serra Kaya Neha Dole Nadja M.Maldonado Luna Natalia Castillo Ryan Potter Jacob P.Rose Joanna Bons christina D.King Jordan B.Burton Birgit Schilling Simon Melov Simon Tang Eric Schaible Tamara Alliston Department of Orthopaedic Surgery University of CaliforniaSan FranciscoCA 94143USA UC Berkeley/UCSF Graduate Program in Bioengineering San FranciscoCA 94143USA Buck Institute for Research on Aging NovatoCA 94945USA Washington University in St Louis Department of OrthopedicsSt.LouisMO 63130USA Advanced Light Source Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

Poor bone quality is a major factor in skeletal fragility in elderly *** molecular mechanisms that establish and maintain bone quality,independent of bone mass,are unknown but are thought to be primarily determined by *** hypothesize that the age-related decline in bone quality results from the suppression of osteocyte perilacunar/canalicular remodeling(PLR),which maintains bone material *** examined bones from young and aged mice with osteocyte-intrinsic repression of TGFβsignaling(TβRII^(ocy−/−))that suppresses *** control aged bone displayed decreased TGFβsignaling and PLR,but aging did not worsen the existing PLR suppression in male TβRII^(ocy−/−)*** relationship impacted the behavior of collagen material at the nanoscale and tissue scale in macromechanical *** effects of age on bone mass,density,and mineral material behavior were independent of osteocytic TGFβ.We determined that the decline in bone quality with age arises from the loss of osteocyte function and the loss of TGFβ-dependent maintenance of collagen integrity.

关键词： maintain primarily integrity

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南岭地区离子吸附型稀土矿床基岩的稀土元素预富集机制探讨

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大地构造与成矿学 2024年第2期48卷 200-212页

作者：豆敬兆王焰谭伟赵子送中国科学院广州地球化学研究所矿物学与成矿学重点实验室广东广州510640 广东省矿物与材料研究开发重点实验室广东广州510640 中国科学院深地科学卓越创新中心广东广州510640 中国科学院大学北京100049

南岭地区离子吸附型稀土矿床是目前全球重稀土的主要来源。在岩浆演化及热液蚀变过程中,稀土元素在成矿基岩中的迁移和富集过程受稀土元素的地球化学行为控制。本文对比了离子吸附型轻、重稀土矿床中基岩在矿物组合、岩石化学及主要稀... 详细信息

南岭地区离子吸附型稀土矿床是目前全球重稀土的主要来源。在岩浆演化及热液蚀变过程中,稀土元素在成矿基岩中的迁移和富集过程受稀土元素的地球化学行为控制。本文对比了离子吸附型轻、重稀土矿床中基岩在矿物组合、岩石化学及主要稀土矿物类型等方面的差异,简要介绍了南岭地区离子吸附型稀土矿床基岩中热液活动与稀土元素富集的相关研究进展。其中富重稀土矿床的基岩主要为高硅碱长花岗岩(SiO_(2)>75%),基岩中硅铍钇矿和氟碳钙钇矿为主要稀土矿物。岩浆期后热液过程中,早期形成的氟铈矿等轻稀土矿物可导致残余流体富集重稀土元素,并形成重稀土热液矿物,稀土氯络合物可能是流体中迁移并富集重稀土元素的主要介质。而富轻稀土矿床的基岩主要为黑云母花岗岩、花岗闪长岩等(SiO_(2)<75%),主要稀土矿物为褐帘石和榍石,为岩浆演化晚期结晶产物,其在后期含F^(−)、CO_(3)^(2−)/HCO_(3)^(–)流体作用下蚀变成氟碳钙铈矿;这一过程导致轻稀土元素在基岩中被重新活化并再次富集。含F^(−)、CO_(3)^(2−)/HCO_(3)^(–)流体可能与南岭地区地下水的贡献有关。

关键词：南岭地区离子吸附型稀土矿床花岗质基岩热液蚀变稀土富集

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离子吸附型稀土矿床的诱导成矿学研究

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大地构造与成矿学 2024年第2期48卷 293-301页

作者：李宁波王焰朱建喜杨武斌中国科学院广州地球化学研究所矿物学与成矿学重点实验室/广东省矿物物理与材料研究开发重点实验室广东广州510640 中国科学院深地科学卓越创新中心广东广州510640 中国科学院大学北京100049

诱导成矿学的核心理念是针对低品位矿石、尾矿和具有成矿潜力岩石中的关键金属资源,通过人工干预手段诱导目标金属元素活化和富集,在有限的时间尺度内形成具有经济价值的可利用资源。离子吸附型稀土矿床是全球稀土资源的主要来源之一,... 详细信息

诱导成矿学的核心理念是针对低品位矿石、尾矿和具有成矿潜力岩石中的关键金属资源,通过人工干预手段诱导目标金属元素活化和富集,在有限的时间尺度内形成具有经济价值的可利用资源。离子吸附型稀土矿床是全球稀土资源的主要来源之一,近年来为全球提供了80%以上的中、重稀土资源供给。该类矿床的形成主要受控于内生稀土初始富集和表生风化淋积成矿两个过程,而后者对于成矿极为关键。由于我国华南地区具有适宜形成离子吸附型稀土矿床的气候条件、大量出露的花岗质岩石及风化壳,因此对该地区开展人工诱导成矿技术研发将具有重要应用前景。通过分析离子吸附型稀土矿床形成的控制因素,预计可选择具有成矿潜力的花岗岩、含稀土风化壳和低品位矿床作为主要诱导成矿对象。通过调控地形地貌、生态、水文和风化壳物理化学条件等加速风化进程,促进稀土元素释放,引导稀土元素定向迁移,并在指定位置进行沉淀成矿,形成具有经济价值的富集稀土的矿体。特别是在该过程中可控制轻重稀土元素的分异,促使其形成富集重稀土的矿体,为解决全球重稀土资源紧缺和保障重稀土资源持续供给提供有效实施方案。因此,对离子吸附型矿床开展诱导成矿学研究具有重要的理论意义和应用价值,可作为诱导成矿学的重点研究方向之一。

关键词：诱导成矿学离子吸附型稀土矿床风化过程稀土元素迁移沉淀

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Management Practices of Locally Advanced and Metastatic Urothelial Carcinoma: A Questionnaire-Based Survey among Lebanese Oncologists

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Open Journal of Urology 2024年第2期14卷 138-149页

作者： Joseph Kattan Sally Temraz Fadi Nasr Arafat Tfayli christina Khater Anas Mugharbel Hady Ghanem Hampig Raphael Kourie Georges Hachem Sarah Masri Jamil Debs Ali Shamseddine Department of Hematology-Oncology H&#244tel-Dieu de France University Hospital Faculty of Medicine Saint-Joseph University of Beirut Beirut Lebanon Department of Internal Medicine Hematology-Oncology Division American University of Beirut Medical Center Beirut Lebanon Hematology-Oncology Division American University of Beirut Medical Center Beirut Lebanon Department of Hematology-Oncology Saint Charles Hospital Beirut Lebanon Department of Internal Medicine Makassed General Hospital Beirut Lebanon Hematology-Oncology Division Lebanese American University Medical Center - Rizk Hospital Beirut Lebanon Department of Hematology-Oncology Saint George Hospital University Medical Center Beirut Lebanon Pfizer Medical Affairs Beirut Lebanon

Background and Objective: The outcome of locally advanced and metastatic urothelial carcinoma LA/mUC has improved over the past years with a plethora of new treatments and the approval of immune checkpoint inhibitors (ICIs), antibody-drug conjugates, and targeted agents, to identify locally advanced metastatic urothelial carcinoma’s current management practices in Lebanon and the implication of the ongoing economic crisis on the medical practice. Methods: An online questionnaire was used to survey ten Lebanese oncologists from six different hospitals, between July 5 and July 11, 2022, requesting information pertaining to their current clinical practice in the pharmacological treatment of locally advanced metastatic urothelial carcinoma. Key Findings: Cisplatin-based chemotherapy was the most frequently reported initial treatment of locally advanced metastatic urothelial carcinoma. Participants reported using immune checkpoint inhibitors in platinum-ineligible patients and those with PDL1 positive tumors. Also, they would not consider the concomitant use of immunotherapy and chemotherapy in the first-line setting. Participants believed that avelumab maintenance is effective in the absence of progression after first-line platinum-based chemotherapy;they would consider initiating it 2 - 10 weeks after completion of chemotherapy. Conclusions and Clinical Implications: After comparing with current international guidelines, this study shows that Lebanese oncologists follow international guidelines and have deep knowledge of recent clinical trials for the management of locally advanced metastatic urothelial carcinoma, regardless of economic crisis challenges.

关键词： Clinical Practice Chemotherapy Immune Checkpoint Inhibitors PDL1 Urothelial Carcinoma

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The Effectiveness of Partnership in Talent Training Between Industry and Higher Vocational Colleges in China

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Journal of Sociology Study 2024年第1期14卷 54-68页

作者： CHEN Yan christina Andin Shandong Vocational College of Light Industry ZiboShandongChina Universiti Malaysia Sabah Malaysia

This paper is based on the partnership between China’s higher vocational colleges and industry, and obtains a large number of data on industry-college partnerships through case analysis, interviews and questionnaires. This paper analyzes the main factors that affect industry-college partnerships and the current problems and challenges, then puts forward the solutions.

关键词： industry-college partnerships environmental factors training factors people factors

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Contrasting oxidation states of low-Ti and high-Ti magmas control Ni-Cu sulfide and Fe-Ti oxide mineralization in Emeishan Large Igneous Province

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Geoscience Frontiers 2022年第6期13卷 41-58页

作者： Yonghua Cao christina Yan Wang Key Laboratory of Metallogenic Prediction of Nonferrous Metals and Geological Environment Monitoring Ministry of EducationSchool of Geosciences and Info-PhysicsCentral South UniversityChangsha 410083China Key Laboratory of Mineralogy and Metallogeny Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China CAS Center for Excellence in Deep Earth Science Guangzhou 510640China Guangdong Provincial Key Laboratory of Mineral Physics and Materials Guangzhou 510640China

Magmatic Ni-Cu-(PGE) sulfide and Fe-Ti oxide deposits in plume-related large igneous provinces(LIPs)are commonly related to low-Ti and high-Ti series magmas, respectively, but the major factors that control such a relationship of metallogenic types and magma compositions are unclear. Magma fOcontrols sulfur status and relative timing of Fe-Ti oxide saturation in mafic magmas, which may help clarify this issue. Taking the Emeishan LIP as a case, we calculated the magma fOof the high-Ti and low-Ti picrites based on the olivine-spinel oxygen barometer, and the partitioning of V in olivine. The obtained fOof the high-Ti series magma(FMQ + 1.1 to FMQ + 2.6) is higher than that of the low-Ti series magma(FMQ-0.5to FMQ + 0.5). The magma fOof the high-Ti and low-Ti picrites containing Fo > 90 olivine reveals that the mantle source of the high-Ti series is likely more oxidized than that of the low-Ti series. The results using the ’lambda REE’ approach show that the high-Ti series may have been derived from relatively oxidized mantle with garnet pyroxenite component. The S contents at sulfide saturation(SCSS) of the two series magmas were calculated based on liquid compositions obtained from the alpha Melts modeling, and the results show that the low-Ti series magma could easily attain the sulfide saturation as it has low fOwith S being dominantly as S. In contrast, the oxidized high-Ti series magma is difficult to attain the sulfide saturation, but could crystallize Fe-Ti oxides at magma MgO content of ~7.0 wt.%. Thus, contrasting magma fOof low-Ti and high-Ti series in plume-related LIPs may play an important role in producing two different styles of metallogeny.

关键词： Emeishan large igneous province Mantle plume High-Ti and low-Ti series magma Magma oxygen fugacity Magmatic Fe-Ti oxide deposits Magmatic Ni-Cu-(PGE)deposits

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