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渥太华声明:人体医疗类干预临床试验研究方案信息与结果的国际注册原则(第Ⅰ部分)

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中国循证儿科杂志 2006年第2期1卷 155-159页

作者： Karmela Krleza-Jeric An-Wen Chan Kay Dickersin Ida Sim Jeremy Grimshaw christian Gluud 刘建平(翻译) 张晶(翻译) 陈君超(翻译) 随机对照试验中心加拿大卫生研究学院多伦多大学医学系布朗大学社区健康系加利福尼亚大学医学系临床流行病学项目渥太华卫生研究学院欧洲临床研究基础设施网络哥本哈根临床试验中心临床干预研究中心 Cochrane肝胆疾病组哥本哈根大学医院(丹麦国家医院)丹麦哥本哈根北京中医药大学循证医学中心上海中医药大学中医循证医学中心上海201203

1目的渥太华声明旨在为临床试验注册建立国际认可的标准（第Ⅰ部分），以及根据这一标准提议的操作方案（第Ⅱ部分）。

关键词：临床试验研究国际注册信息医疗国际认可标准

旱作及水作条件下稻田CH_4和N_2O排放的观察研究

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土壤学报 2003年第6期40卷 864-869页

作者：李曼莉徐阳春沈其荣周春霖黄新宇殷晓燕尹金来 Dittert K 南京农业大学资源与环境科学学院南京210095 江苏沿海地区农业科学研究所江苏盐城224002 德国基尔大学

通过田间试验研究不同土表覆盖处理旱作和水作水稻全生育期内土壤微量气体的排放。结果表明 ,旱作稻田当季N2 O的排放总量是水作稻田的 5～ 6倍 ,而水作稻田CH4 的排放总量是旱作稻田的8～ 1 9倍。不同覆盖旱作处理N2 O的排放总量为 :裸... 详细信息

通过田间试验研究不同土表覆盖处理旱作和水作水稻全生育期内土壤微量气体的排放。结果表明 ,旱作稻田当季N2 O的排放总量是水作稻田的 5～ 6倍 ,而水作稻田CH4 的排放总量是旱作稻田的8～ 1 9倍。不同覆盖旱作处理N2 O的排放总量为 :裸露 >覆膜 >盖草 ,CH4 排放总量为 :覆膜 >裸露 >盖草。水作稻田CH4 的排放与水稻生育期关系密切 ,以分蘖盛期的 5 0mgm- 2 h- 1为最大。旱作稻田N2 O的排放与施氮关系密切 ,其排放通量峰值出现的时间因施氮时期不同而异 ,基肥的峰值 (2 1 1 6 7μgm- 2 h- 1)出现在施肥后第 1 1d ;分蘖肥的峰值 (4 3 94 3 μgm- 2 h- 1)出现在施肥后第 9～ 1 0d ;穗肥的峰值则在施肥后的第 6d出现 ,达 3 3 3 5 0 μgm- 2 h- 1。

关键词：旱作水作稻田 CH4 N2O 排放量土表覆盖

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杭州RAFFLES城

城市环境设计 2010年第1期 36-39页

作者： Ben van Berkel Caroline Bos Astrid Piber Hannes Pfau Markus van Aalderen Juliane Maier Marc Salemink Andreas Bogenschuetz Marina Bozukova Brendon Carlin Miklos Deri Gary Freedman Juergen Heinzel Alexander Hugo Abhijit Kapade Marcin Koltunski Fernie Lai James Leng Tom Minderhoud Peter Moerland Rudi Nieveen Hans-Peter Nuenning Hyunil Oh Steffen Riegas Rikjan Scholten Ioana Sulea christian Veddeler Rein Werkhoven Georg Willheim UNStudio

杭州Raffles城发展坐落于浙江省省会杭州市的钱塘江边,是嘉德置地继新加坡、上海、北京、成都和巴林之后的第六栋,将零售店、办公楼、住户和酒店设施融于一体,成为新城区的文化地标。

关键词：杭州浙江文化地标 RAFFLES 城市背景杭州市新城区嘉德 Lake 办公楼零售店

The impact of COVID-19 on the birth rate in Nigeria:a report from population-based registries

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Infectious Diseases Research 2023年第1期4卷 14-18页

作者： Charlotte Blanche Oguejiofor Kenechi Miracle Ebubechukwu George Uchenna Eleje Emmanuel Onyebuchi Ugwu Joseph Tochukwu Enebe Kingsley Emeka Ekwuazi Chukwuemeka Chukwubuikem Okoro Boniface Chukwuneme Okpala Charles Chukwunomunso Okafor Nnanyelugo Chima Ezeora Emeka Ifeanyi Iloghalu Chidebe christian Anikwe Chigozie Geoffrey Okafor Polycarp Uchenna Agu Emeka Philip Igbodike Iffiyeosuo Dennis Ake Arinze Anthony Onwuegbuna Osita Samuel Umeononihu Onyedika Promise Anaedu Odigonma Zinobia Ikpeze David Chibuike Ikwuka Henry Ifeanyi Nwaolisa Ekene Agatha Emeka Jude Ogechukwu Okoye Ihechinyerem Kelechi Osuagwu Angela Ogechukwu Ugwu Toochukwu Benjamin Ejikeme Eziamaka Pauline Ezenkwele Chijioke Ogomegbunam Ezeigwe Malarchy Ekwunife Nwankwo Gerald Okanandu Udigwe Joseph Ifeanyichukwu Ikechebelu Grace Agbaeze Chukwuebuka Divine Nwanja Ahizechukwu Chigoziem Eke Department of Obstetrics and Gynecology Nnamdi Azikiwe University Teaching HospitalNnewi PMB 5025Nigeria Preventive Medicine and Research Department Clina-Lancet LaboratoriesVictoria IslandLagos 101241Nigeria Effective Care Research Unit Department of Obstetrics and GynecologyNnamdi Azikiwe UniversityNnewi Campus 435001Nigeria Department of Obstetrics and Gynecology College of MedicineUniversity of Nigeria Enugu CampusEnuguEnugu State 400102Nigeria Department of Obstetrics and Gynecology University of Nigeria Teaching HospitalItuku OzallaEnugu State 400102Nigeria Department of Obstetrics and Gynecology ESUT Teaching HospitalParklaneEnugu 400102Nigeria Medical Department Divine Medical CentreSouth West IkoyiLagos 1001233Nigeria Department of Obstetrics and Gynecology Havana Specialist HospitalSurulereLagos 100011Nigeria Clinical Trial Division Drug Evaluation and Research DirectorateNAFDAC office ComplexLagos 100011Nigeria Department of Ophthalmology Nnamdi Azikiwe UniversityNnewi campus 435001Nigeria Department of Human Physiology Nnamdi Azikiwe University NnewiAnambra State 435001Nigeria Department of Family Medicine Faculty of MedicineNnamdi Azikiwe UniversityAwka 435001Nigeria Department of Medical Laboratory Science Faculty of Health Sciences and TechnologyNnamdi Azikiwe UniversityAwka 435001Nigeria Department of Health Services Federal University of TechnologyOwerri 460103Nigeria Department of Haematology and Immunology College of MedicineUniversity of Nigeria Enugu CampusEnuguEnugu State 400102Nigeria Musgrove Park Hospital Somerset NHS Foundation TrustUnited Kingdom TLTp Medical(UHS) Southampton WS15United Kingdom Division of Maternal Fetal Medicine Department of Gynecology and ObstetricsJohns Hopkins University School of MedicineBaltimore 21201U.S.A

Background and objectives:Coronavirus disease 2019(COVID-19)is a pandemic that has become a major source of morbidity and mortality worldwide,affecting the physical and mental health of individuals influencing *** the threat,it poses to maternal health in sub-Saharan Africa and Nigeria,there is little or no data on the impact it has on fertility,conception,gestation and *** compare the birth rate between pre-COVID and COVID times using selected months of the *** and methods:This was a secondary analysis of cross-sectional analytical study data from the birth registries of three tertiary hospitals,comparing two years[2019(Pre-COVID)]versus[2020(COVID era)]using three months of the year(October to December).The data relied upon was obtained from birth registries in three busy maternity clinics all within tertiary hospitals in South-East Nigeria and we aimed at discussing the potential impacts of COVID-19 on fertility in *** secondary outcome measures were;mode of delivery,booking status of the participants,maternal age and ***:There was a significant decrease in tertiary-hospital based birth rate by 92 births(P=0.0009;95%CI:-16.0519 to-4.1481)among mothers in all the three hospitals in 2020 during the COVID period(post lockdown months)of October to *** was a significant difference in the mode of delivery for mothers(P=0.0096)with a 95%confidence interval of 1.0664 to 1.5916,as more gave birth through vaginal delivery during the 2020 COVID-19 period than ***:Tertiary-hospital based birth rates were reduced during the *** multi-centre study extrapolated on possible factors that may have played a role in this decline in their birth rate,which includes but is not limited to;decreased access to hospital care due to the total lockdowns/curfews and worsening inflation and economic recession in the country.

关键词： birth rates COVID-19 lockdown Nigeria pandemic pre-COVID

大肠杆菌与肠球菌属共感染可能是新生仔猪腹泻主要诱因

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猪业科学 2018年第12期35卷 31-31页

作者： Marie Louise Hermann-Bank Kerstin Skovgaard Anders Stockmarr Mikael Lenz Strube Niels Larsen Hanne Kongsted Hans-christian Ingerslev Lars M lbak Mette Boye

新生仔猪腹泻是近年来造成养猪业严重经济损失的主要疾病之一,该病发病率、死亡率高,除造成仔猪日增重降低,严重的病例引起死亡外,还会破坏仔猪肠道正常菌群的定植,影响肠道微环境,进而造成持续性损伤,致使仔猪生长发育受阻,严重影响猪... 详细信息

新生仔猪腹泻是近年来造成养猪业严重经济损失的主要疾病之一,该病发病率、死亡率高,除造成仔猪日增重降低,严重的病例引起死亡外,还会破坏仔猪肠道正常菌群的定植,影响肠道微环境,进而造成持续性损伤,致使仔猪生长发育受阻,严重影响猪场经济效益。该病病因尚未明了。传统的肠道致病病原像梭状芽孢杆菌、隐孢子虫、溶血性大肠杆菌等并不能单独诱发该病,PEDV、TGEV等冠状病毒和轮状病毒似乎也和该病无关。从目前的有关报道和数据来看,新生仔猪腹泻更有可能是由多种病原和复合因素引发的疾病,所以现在越来越多的研究开始倾向于从肠道微生物的组成和菌群数量变化中寻找答案。

关键词：溶血性大肠杆菌仔猪腹泻新生共感染肠球菌诱因梭状芽孢杆菌正常菌群

人体医疗类干预临床试验研究方案信息与结果的国际注册原则——渥太华声明(第Ⅰ部分)

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循证医学 2006年第2期6卷 109-112页

作者：刘建平张晶陈均超 Karmela Krle■a-Jeri An-Wen Chan Kay Dickersin Ida Sim Jeremy Grimshaw christian Gluud 北京中医药大学循证中医药临床研究与评价中心北京100029 上海市中医药循证医学中心上海201203 加拿大渥太华加拿大卫生研究学院随机对照试验中心

临床试验的注册在国际临床医学界已经呼吁了多年,其用意在于避免发表偏倚(一种阳性结果临床试验容易获得发表,而阴性的研究结果不容易获得发表的倾向)和选择性报告偏倚。2004年一个由80多名国际临床医学专家、杂志编辑和研究人员共同签... 详细信息

临床试验的注册在国际临床医学界已经呼吁了多年,其用意在于避免发表偏倚(一种阳性结果临床试验容易获得发表,而阴性的研究结果不容易获得发表的倾向)和选择性报告偏倚。2004年一个由80多名国际临床医学专家、杂志编辑和研究人员共同签署的声明,由6名具有国际知名度的临床试验专家起草、修订和发表了注册临床试验的宣言,即著名的《渥太华声明》。要求任何临床试验的研究方案及随后的试验结果都应当进行注册,并使公众能够获取。该声明已经翻译成英、法、日文;现由国内学者翻译的该声明在本刊发表具有重要意义,将进一步促进临床试验的规范化和质量的提高,并最终接受公众的评价。

关键词：临床试验注册渥太华声明

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用沉积物追溯海啸

环球科学 2020年第15期 18-18页

作者：克里斯琴·福格蒂龚聪(翻译) 不详

2004年,印度洋地震引发的海啸从苏H答腊岛向外传播,摧毁了很多东南亚沿海地区。虽然海啸也传播到了非洲,却没有造成太大破坏。很多科字家因此认为非洲东部部分地区的海啸风险较低。在坦桑尼亚东北部的潘加尼湾,一项新研究调查了当地有1... 详细信息

2004年,印度洋地震引发的海啸从苏H答腊岛向外传播,摧毁了很多东南亚沿海地区。虽然海啸也传播到了非洲,却没有造成太大破坏。很多科字家因此认为非洲东部部分地区的海啸风险较低。在坦桑尼亚东北部的潘加尼湾,一项新研究调查了当地有1000年历史且富含人类遗骨的砂层,将海啸巨浪重新带回人们的视线。

关键词：海啸非洲东部沿海地区坦桑尼亚印度洋沉积物地震东南亚

Families of Dothideomycetes

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Fungal Diversity 2013年第6期63卷 1-313页

作者： Kevin D.Hyde E.B.Gareth Jones Jian-Kui Liu Hiran Ariyawansa Eric Boehm Saranyaphat Boonmee Uwe Braun Putarak Chomnunti Pedro W.Crous Dong-Qin Dai Paul Diederich Asha Dissanayake Mingkhuan Doilom Francesco Doveri Singang Hongsanan Ruvishika Jayawardena James D.Lawrey Yan-Mei Li Yong-Xiang Liu Robert Lücking Jutamart Monkai Lucia Muggia Matthew P.Nelsen Ka-Lai Pang Rungtiwa Phookamsak Indunil C.Senanayake Carol A.Shearer Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Nalin N.Wijayawardene Saowanee Wikee Hai-Xia Wu Ying Zhang Begoña Aguirre-Hudson S.Aisyah Alias AndréAptroot Ali H.Bahkali Jose L.Bezerra D.Jayarama Bhat Erio Camporesi Ekachai Chukeatirote Cécile Gueidan David L.Hawksworth Kazuyuki Hirayama Sybren De Hoog Ji-Chuan Kang Kerry Knudsen Wen-Jing Li Xing-Hong Li Zou-Yi Liu Ausana Mapook Eric H.C.McKenzie Andrew N.Miller Peter E.Mortimer Alan J.L.Phillips Huzefa A.Raja christian Scheuer Felix Schumm Joanne E.Taylor Qing Tian Saowaluck Tibpromma Dhanushka N.Wanasinghe Yong Wang Jian-Chu Xu Supalak Yacharoen Ji-Ye Yan Min Zhang Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201Yunnan China World Agroforestry Centre East Asia NodeHeilongtanKunming 650201China Institute of Excellence in Fungal Research Chiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Institute Ocean Earth Sciences Kuala Lumpur 50603SelangorMalaysia Department of Botany and Microbiology King Saudi UniversityRiyadhSaudi Arabia 42 Longacre Drive LivingstonNJ 07039USA Institut für Biologie Bereich Geobotanik und Botanischer GartenHerbariumMartin-Luther-UniversitätNeuwerk 2106099 Halle(Saale)Germany CBS-KNAW Fungal Biodiversity Centre Uppsalalaan 83584CT UtrechtThe Netherlands Musée National d’histoire Naturelle 25 rue Munster2160 LuxembourgLuxembourg Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesBeijing 100097People’s Republic of China Via dei Funaioli 22 57126 LivornoItaly Department of Environmental Science and Policy George Mason University4400 University DriveFairfaxVA 22030-4444USA International Fungal Research and Development Centre Key Laboratory of Resource Insect Cultivation&Utilization State Forestry AdministrationKunming 650224People’s Republic of China The Research Institute of Resource Insects Chinese Academy of ForestryKunming 650224People’s Republic of China Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyangGuizhou 550006People’s Republic of China Science and Education Integrative Research(Botany)The Field Museum1400 South Lake Shore DriveChicagoIL 60605-2496USA Institute of Plant Sciences University of GrazHolteigasse 68010 GrazAustria Department of Life Science University of TriesteVia L.Giorgieri 10TriesteItaly Committee on Evolutionary Biology University of Chicago1025 E.57th StreetChicagoIL 60637USA Institute ofMarine Biology and Center of Excellence for the Oceans Taiwan

Dothideomycetes comprise a highly diverse range of fungi characterized mainly by asci with two wall layers(bitunicate asci)and often with fissitunicate *** species are saprobes,with many asexual states comprising important plant *** are also endophytes,epiphytes,fungicolous,lichenized,or lichenicolous *** occur in terrestrial,freshwater and marine habitats in almost every part of the *** accept 105 families in Dothideomycetes with the new families Anteagloniaceae,Bambusicolaceae,Biatriosporaceae,Lichenoconiaceae,Muyocopronaceae,Paranectriellaceae,Roussoellaceae,Salsugineaceae,Seynesiopeltidaceae and Thyridariaceae introduced in this *** family is provided with a description and notes,including asexual and asexual states,and if more than one genus is included,the type genus is also *** family is provided with at least one figure-plate,usually illustrating the type genus,a list of accepted genera,including asexual genera,and a key to these genera.A phylogenetic tree based on four gene combined analysis add support for 64 of the families and 22 orders,including the novel orders,Dyfrolomycetales,Lichenoconiales,Lichenotheliales,Monoblastiales,Natipusillales,Phaeotrichales and *** paper is expected to provide a working document on Dothideomycetes which can be modified as new data comes to *** is hoped that by illustrating types we provide stimulation and interest so that more work is carried out in this remarkable group of fungi.

关键词： Acrospermales Asterinales Botryosphaeriales Capnodiales Dothideales Dyfrolomycetales Hysteriales Jahnulales Lichenoconiales Lichenotheliales Microthyriales Monoblastiales Myriangiales Mytilinidiales Natipusillales Patellariales Phaeotrichales Phylogeny Pleosporales Strigulales Taxonomy Trypetheliales Tubeufiales Type species Venturiales

Latest development status of Qcells *** NEO technology

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