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网架式网箱浮架结构设计载荷与屈服强度分析

哈尔滨工程大学学报 2022年第3期43卷 340-347页

作者：孙树政李辉 Muk Chen ong 李琳哈尔滨工程大学烟台研究(生)院山东烟台264000 哈尔滨工程大学船舶工程学院黑龙江哈尔滨150001 斯塔万格大学机械结构工程和材料科学系罗加兰郡斯塔万格4036

网架式模块化深远海养殖平台由多个网架式网箱模块组合而成,能更好的适应深远海环境。为便于分析网箱模块浮架结构强度,本文不考虑网衣的作用,只针对单个网箱模块浮架结构屈服强度开展研究。采用Morison方程结合CFD计算的网架结构水动... 详细信息

网架式模块化深远海养殖平台由多个网架式网箱模块组合而成,能更好的适应深远海环境。为便于分析网箱模块浮架结构强度,本文不考虑网衣的作用,只针对单个网箱模块浮架结构屈服强度开展研究。采用Morison方程结合CFD计算的网架结构水动力系数,计算网箱浮架结构波浪载荷响应,确定设计波参数,计算得到设计载荷。然后应用有限元方法,计算浮架结构在设计载荷下的应力响应,对结构的屈服强度进行校核,对球、管节点进行网格细化以对其进行局部强度分析。研究结果表明设计的网架式网箱浮架结构在6 m波高下结构屈服强度满足规范要求。

关键词：网架式网箱深远海养殖浮架结构设计载荷 Morison方程水动力系数屈服强度

3D-CTBA指导下单孔胸腔镜精准肺亚段切除术外科临床应用初步结果

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哈尔滨医科大学学报 2024年第1期58卷 41-46页

作者：陆军李宛霖孔祥龙徐世东徐海哈尔滨医科大学附属肿瘤医院胸外科黑龙江哈尔滨150081

目的评估三维计算机断层支气管血管成像(three dimensional computed tomography bronchography and angiography,3D-CTBA)指导下单孔胸腔镜肺亚段切除术治疗肺部小结节的安全性和可行性。方法对哈尔滨医科大学附属肿瘤医院胸外科2020... 详细信息

目的评估三维计算机断层支气管血管成像(three dimensional computed tomography bronchography and angiography,3D-CTBA)指导下单孔胸腔镜肺亚段切除术治疗肺部小结节的安全性和可行性。方法对哈尔滨医科大学附属肿瘤医院胸外科2020年10月~2022年9月完成的30例单孔胸腔镜肺亚段切除术病例进行回顾性分析,包括其围术期临床特点和短期预后。所有患者均在术前行3D-CTBA。结果30例患者均接受了单孔胸腔镜肺亚段切除术,无中转开胸,1例患者因切缘不足改行肺叶切除,1例患者因淋巴结钙化术中失血500 mL,无围术期死亡。平均切缘(27.8±8.0)mm,平均手术时间(203.8±57.5)min,术中失血50 mL(30~500 mL)。术后并发症:延长漏气大于3天者2例,肺炎1例,心律失常2例,肺不张1例。术后病理:原位腺癌1例,微浸润腺癌10例,浸润性非黏液腺癌17例,良性病变2例。平均随访(19.4±7.1)月,30例患者均无复发及转移。结论3D-CTBA指导下单孔胸腔镜肺亚段切除术安全可行,肿瘤学疗效满意,可用于治疗肺部小结节。

关键词：亚段肺亚段切除术单孔胸腔镜三维重建肺结节早期肺癌

Large animal models of cardiac ischemia-reperfusion injury:Where are we now?

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Zoological Research 2023年第3期44卷 591-603页

作者： Attaur Rahman Yuhao Li To-Kiu Chan Hui Zhao Yaozu Xiang Xing Chang Hao Zhou Dachun Xu Sang-Bing ong Department of Medicine and Therapeutics Faculty of MedicineThe Chinese University of Hong Kong(CUHK)Hong Kong SARChina Centre for Cardiovascular Genomics and Medicine(CCGM) Lui Che Woo Institute Innovative MedicineThe Chinese University of Hong Kong(CUHK)Hong Kong SARChina College of Veterinary Sciences and Animal Husbandry Abdul Wali Khan University MardanMardanKhyber Pakhtunkhwa 23200Pakistan School of Biomedical Sciences CUHK-GIBH CAS Joint Laboratory on Stem Cell and Regenerative MedicineThe Chinese University of Hong Kong(CUHK)Hong Kong SARChina Institute for Tissue Engineering and Regenerative Medicine(iTERM) The Chinese University of Hong Kong(CUHK)Hong Kong SARChina SBS Core Laboratory CUHK Shenzhen Research InstituteShenzhenGuangdong 518172China Kunming Institute of Zoology–The Chinese University of Hong Kong(KIZ-CUHK)Joint Laboratory of Bioresources and Molecular Research of Common Diseases Hong Kong SARChina Shanghai East Hospital Key Laboratory of Arrhythmias of the Ministry of Education of ChinaSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China Guang’anmen Hospital China Academy of Chinese Medical SciencesBeijing 100053China Department of Cardiology Chinese People’s Liberation Army General HospitalBeijing 100853China Center for Cardiovascular Research and Alternative Medicine University of Wyoming College of Health SciencesLaramieWY 82071USA Department of Cardiology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China Hong Kong Hub of Paediatric Excellence(HK HOPE) Hong Kong Children’s Hospital(HKCH)Kowloon BayHong Kong SARChina CUHK Shenzhen Research Institute(SZRI) ShenzhenGuangdong 518172China Neural Vascularand Metabolic Biology Thematic Research ProgramSchool of Biomedical SciencesThe Chinese University of Hong Kong(CUHK)Hong Kong SARChina

Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical ***,current cardioprotective strategies/interventions formulated in preclinical cardiovascular research are often limited to small animal models,which are not transferable or reproducible in large animal models due to different factors such as:(i)complex and varied features of human ischemic cardiac disease(ICD),which are challenging to mimic in animal models,(ii)significant differences in surgical techniques applied,and(iii)differences in cardiovascular anatomy and physiology between small versus large *** article highlights the advantages and disadvantages of different large animal models of preclinical cardiac ischemic reperfusion injury(IRI),as well as the different methods used to induce and assess IRI,and the obstacles faced in using large animals for translational research in the settings of cardiac IR.

关键词： Cardiovascular disorder Ischemic cardiac disease Ischemic-reperfusion injury Large animal model Myocardial infarction Translational gap

菊花倍半萜烯内酯诱导人鼻咽癌细胞毒性和凋亡的研究

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中草药 2002年第10期33卷 909-912页

作者：林忠宁林育纯 SHEN Han-ming YANG Cheng-feng ong choon-nam 中山大学公共卫生学院广东广州510089 Depart of Community Occupational and Family MedicineFaculty of MedicineMD3National University of SingaporeSingapore 117597

目的　评价菊花倍半萜烯内酯类化合物 (SL s)对鼻咽癌的抗肿瘤作用。方法　采用 SL s的活性成分parthenolide (PN)为受试物作用于人鼻咽癌高分化细胞株 CNE1,检测细胞毒性和诱导性凋亡指标 ,进行时间 -效应和剂量 -效应作用观察。结果　... 详细信息

目的　评价菊花倍半萜烯内酯类化合物 (SL s)对鼻咽癌的抗肿瘤作用。方法　采用 SL s的活性成分parthenolide (PN)为受试物作用于人鼻咽癌高分化细胞株 CNE1,检测细胞毒性和诱导性凋亡指标 ,进行时间 -效应和剂量 -效应作用观察。结果　 10～ 10 0 μm ol/ L 的 PN作用 6～ 36 h后与阴性对照组比较 ,CNE1细胞乳酸脱氢酶 (L DH)漏出率明显增加、细胞计数减少、细胞增殖抑制率升高 (P<0 .0 5 ) ;细胞出现凋亡特征形态学改变 ,TU NEL阳性细胞、Sub G1亚群细胞百分数增加 ,细胞失贴壁率明显增高 (P<0 .0 5 ) ;上述指标与 PN剂量存在明显相关 (P<0 .0 5 )和时间循序变化。结论　 PN可通过对人鼻咽癌细胞毒性作用和诱导细胞凋亡发挥其抗肿瘤作用 ,提示

关键词：菊花倍半萜烯内酯鼻咽肿瘤抗肿瘤作用细胞凋亡 NPC

装配式空心剪力墙结构施工关键技术研究与应用

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建筑技术 2024年第15期55卷 1887-1890页

作者：李国经宋佳峰赵跃龙王鹏程北京建工四建工程建设有限公司北京100075

装配式空心板剪力墙结构作为一种新型装配式结构体系,具有板型尺寸小、重量轻、抗震性能优越、工程造价低的优点,但也存在安装易受扰动、模板加固较难等问题。通过介绍装配式空心剪力墙体系施工特点,依托顺义仁和镇临河村棚户区改造土... 详细信息

装配式空心板剪力墙结构作为一种新型装配式结构体系,具有板型尺寸小、重量轻、抗震性能优越、工程造价低的优点,但也存在安装易受扰动、模板加固较难等问题。通过介绍装配式空心剪力墙体系施工特点,依托顺义仁和镇临河村棚户区改造土地开发项目,针对预制空心剪力墙的施工过程研究其关键施工技术,并根据目前施工中常见问题提供了有效的施工质量控制措施与解决方案。

关键词：装配式结构装配式构件空心剪力墙板

AtomSets as a hierarchical transfer learning framework for small and large materials datasets

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npj Computational Materials 2021年第1期7卷 1575-1583页

作者： Chi Chen Shyue Ping ong Department of NanoEngineering University of California San Diego9500 Gilman DrMail Code 0448La JollaCA 92093-0448USA

Predicting properties from a material’s composition or structure is of great interest for materials *** learning has recently garnered considerable interest in materials predictive tasks with low model errors when dealing with large materials ***,deep learning models suffer in the small data regime that is common in materials *** we develop the AtomSets framework,which utilizes universal compositional and structural descriptors extracted from pre-trained graph network deep learning models with standard multi-layer perceptrons to achieve consistently high model accuracy for both small compositional data(130,000).The AtomSets models show lower errors than the graph network models at small data limits and other non-deep-learning models at large data *** also transfer better in a simulated materials discovery process where the targeted materials have property values out of the training data *** models require minimal domain knowledge inputs and are free from feature *** presented AtomSets model framework can potentially accelerate machine learning-assisted materials design and discovery with less data restriction.

关键词： Sets framework hierarchical

Analysis of the corrosion performance of binder jet additive manufactured magnesium alloys for biomedical applications

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Journal of Magnesium and Alloys 2022年第5期10卷 1296-1310页

作者： Kai Xiang Kuah Daniel J.Blackwood Wee Kit ong Mojtaba Salehi Hang Li Seet Mui Ling Sharon Nai Sudesh Wijesinghe Department of Materials Science&Engineering National University of Singapore9 Engineering Drive 1117575 Singapore Reliability and Characterisation Unit Singapore Institute of Manufacturing Technology(SIMTech)Agency forScienceTechnology and Research(A^(∗)STAR)73 Nanyang Drive637662 Singapore Additive Manufacturing Group Singapore Institute of Manufacturing Technology(SIMTech)Agency forScienceTechnology and Research(A^(∗)STAR)73 Nanyang Drive637662 Singapore

Binder jet printing(BJP)is a state-of-the-art additive manufacturing technique for producing porous magnesium *** MgZn-Zr based BJP samples were assessed for corrosion performance in simulated body fluids by electrochemical and hydrogen evolution *** corrosion rates of the BJP specimens were significantly higher than solid controls,even after accounting for their larger surface areas,suggesting that the BJP microstructure is detrimental to corrosion performance.X-ray computed tomography revealed nonuniform corrosion within the porous structure,with corrosion products forming on the pore *** the pores with hydroxyapatite or polymers greatly improved the corrosion resistance of the BJP samples.

关键词： Magnesium Additive manufacturing Binder jetting Porous Corrosion Biodegradability

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不同外源硒对番茄硒富集及果实品质的影响

湖北农业科学 2024年第5期63卷 65-69页

作者：康宇田腾飞问小龙龙澜殷红清恩施土家族苗族自治州农业科学院湖北恩施445000 湖北省富硒产业技术研究院湖北恩施445000

以番茄为供试材料,采用盆栽试验,研究了2种外源硒亚硒酸钠(Na_(2)SeO_(3))和硒酸钠(Na_(2)SeO_(4))对番茄农艺性状、番茄植株各器官硒含量、硒的富集及番茄果实品质的影响。结果表明,外源硒施用可促进番茄植株的生长发育,且硒酸钠施用... 详细信息

以番茄为供试材料,采用盆栽试验,研究了2种外源硒亚硒酸钠(Na_(2)SeO_(3))和硒酸钠(Na_(2)SeO_(4))对番茄农艺性状、番茄植株各器官硒含量、硒的富集及番茄果实品质的影响。结果表明,外源硒施用可促进番茄植株的生长发育,且硒酸钠施用可显著提高番茄产量;硒酸钠施用显著增加了番茄植株根、茎、叶、果实中的硒含量,且叶对硒的吸收能力最强,而亚硒酸钠处理中根对硒的吸收能力最强;外源硒的添加显著增强了番茄植株对硒的富集能力及从根系向地上部转移硒的能力,提高了番茄果实维生素C及可溶性糖含量,显著改善了番茄果实的品质,且硒酸钠的效果优于亚硒酸钠。

关键词：外源硒番茄硒含量硒富集果实品质

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高性能相位微跃计的关键技术研究

时间频率学报 2024年第1期47卷 8-17页

作者：孙文龙史丰丰徐金锋付桂涛北京卫星导航中心北京100094

定位、导航和定时服务(PNT)已成为国家重要新型基础设施,相位微跃计是PNT基础设施中的核心设备。它是一种对输入频率信号进行精密调整并输出时间频率信号的设备,目前只有美国、德国、俄罗斯等国家有相关成熟产品。随着高性能原子频标和... 详细信息

定位、导航和定时服务(PNT)已成为国家重要新型基础设施,相位微跃计是PNT基础设施中的核心设备。它是一种对输入频率信号进行精密调整并输出时间频率信号的设备,目前只有美国、德国、俄罗斯等国家有相关成熟产品。随着高性能原子频标和光频标的发展,现有相位微跃计性能还是停滞于1~2×10^(-13)/s的水平,已经无法满足对高性能原子频标和光频标的调控需求。本文重点对极小分辨率频率调控技术和低噪声信号处理技术等进行研究,实现了频率分辨率优于1×10^(-19)、相位调整分辨率优于0.023 fs、附加频率稳定度优于3×10^(-14)/s的国产高性能相位微跃计。

关键词：时间频率相位微跃计精密测控频率分辨率频率稳定度