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Mechanism Analysis of Gui Jianyu in treating Hypertension complicated with Impaired Glucose Tolerance Based on Network Pharmacology and Molecular Docking

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TMR Modern Herbal Medicine 2022年第2期5卷 20-28页

作者： Ying Chen Shi-Yi Tao Lu Zhou De-Shuang Yang chong-xiang xue Li Huang China and Japan Friendship School of Clinical Medicine Beijing University of Traditional Chinese MedicineBeijing 100029China School of Traditional Chinese Medicine Beijing University of Traditional Chinese MedicineBeijing 100029China Department of Integrative Cardiology China Japan Friendship HospitalBeijing 100029China

Objective To explore the mechanism of Gui Jianyu(Euonymus alatus(Thunb.)Sieb.)in treating hypertension(HT)complicated with impaired glucose tolerance(IGT)based on network pharmacology and molecular docking *** The main chemical components and targets of Gui Jianyu were obtained from TCMSP *** Swiss Target Prediction platform was used to predict drug-related targets for *** disease targets of HT complicated with IGT were obtained from GenCards,OMIM and DrugBank *** intersection targets of drugs and two diseases were obtained by R and Veen Diagram was *** protein-protein interaction(PPI)network model was constructed in STRING platform and visualized by Cytoscape *** and KEGG analysis on Metascape platform were used to analyse the common *** of main drug components-disease targets-pathways was established with Cytoscape ***,the molecular docking between the core regulatory active components of Gui Jianyu and the core targets were verified by Autodock *** Eight active components and 357 corresponding targets were obtained.681 HT related targets and 727 IGT related targets,196 disease intersection targets,and 57 Gui Jianyu targets in the treatment of HT complicated with IGT were confirmed.20 GO and 19 KEGG main pathways were *** docking of 2 key active ingredients with 2 key targets showed that all results scores were less than-5.0 kcal·*** and kaempferol,the key active components,had good binding activity with AKT1 and *** Gui Jianyu may play a key role in the treatment of HT complicated with IGT by reducing insulin *** work explored the common pathogenesis of HT complicated with IGT,and also provided a reference for further pharmacological research and exploration the efficacy of Gui Jianyu for HT complicated with IGT.

关键词： Network pharmacology Molecular docking Insulin resistance Gui Jianyu Hypertension Impaired glucose tolerance

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会计专业毕业生外语能力要求的调查与分析

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安徽工业大学学报（社会科学版） 2008年第6期25卷 134-135页

作者：张力向崇学安徽工业大学管理学院安徽马鞍山243002

通过问卷调查发现,用人单位对会计专业毕业生外语能力的要求正在逐步提高,但是现行的会计专业的双语教学安排难以满足用人单位的实际需要。应提高任课教师的教学水平,改革现行教学模式,提高会计专业学生的外语能力,增强学生的就业竞争力。

关键词：会计专业毕业生外语能力要求问卷调查

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公允价值计量在我国的应用

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安徽工业大学学报（社会科学版） 2008年第2期25卷 59-61页

作者：向崇学寻导利安徽工业大学管理学院安徽马鞍山243002

我国会计界在应用公允价值计量方面经历了提倡、回避和全面使用的过程。新会计准则下做好应用公允价值计量工作,应建立独立的公充价值计量准则及其框架体系,加大公允价值计量的信息披露,完善资产评估制度。

关键词：公允价值计量相关性可靠性信息披露资产评估

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Preparation of V_2O_5 from converter slag containing vanadium

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Rare Metals 2018年第10期37卷 904-912页

作者： chong Han Liang Li He Yang xiang-Xin xue School of Materials and Metallurgy Northeastern University

Preparation of V2O5 from converter slag （CS） was investigated through roasting, leaching, extracting, and precipitating processes. The corresponding roles of the parameters during every procedure were analyzed in detail. （NH4）2SO4 and KHSO4 were used as fusing agents to transform compounds containing vanadium into soluble species. Mass ratio of （NH4）2SO4 to CS, mass ratio of KHSO4 to CS, and roasting temperature during the roasting process can significantly influence leaching rate of vanadium （LRV）. With H2SO4 as leaching agent, 99.2 % vanadium in CS can be leached out under the optimum leaching conditions, which mainly refer to liquid-to-solid ratio, H2SO4 concentration, leaching temperature, and leaching time. Extracting and back-extracting processes were introduced to purify the vanadium from the H2SO4 lixivium. Extracting rate of vanadium （ERV） greatly depends on iron powder concentration, pH, diisooctyl phosphate （P2O4） content, volume ratio of extractant to H2SO4 lixivium, and extracting time. By adding ammonium hydroxide, 94.0 % vanadium in back-extracting solution can be separated in the form of precipitates. The product from the roasted precipitate mainly consists of V2O5, the content of which is higher than 90.0 %.

关键词： Converter slag V2O5 Roasting Leaching Extracting

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Photocatalytic activity of Fe-doped CaTiO_3 under UV–visible light

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Journal of Environmental Sciences 2014年第7期26卷 1489-1495页

作者： He Yang chong Han xiangxin xue School of Materials and Metallurgy Northeastern University

The photocatalytic degradation of methylene blue（MB） over Fe-doped CaTiO3 under UV-visible light was investigated. The as-prepared samples were characterized using X-ray diffraction（XRD）, scanning electron microscope（SEM） equipped with an energy dispersive spectrometer（EDS） system, Fourier transform infrared spectra（FT-IR）, and UV-visible diffuse reflectance spectroscopy（DRS）. The results show that the doping with Fe significantly promoted the light absorption ability of CaTiO3 in the visible light region. The Fe-doped CaTiO3 exhibited higher photocatalytic activity than CaTiO3 for the degradation of ***, the photocatalytic activity of the Fe-doped CaTiO3 was greatly influenced by the calcination temperature during the preparation process. The Fe-doped CaTiO3 prepared at500°C exhibited the best photocatalytic activity, with degradation of almost 100% MB（10 ppm）under UV-visible light for 180 min.

关键词： Fe-doped CaTiO3 Methylene blue Photocatalytic activity UV-visible light

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A generalizable, data-driven online approach to forecast capacity degradation trajectory of lithium batteries

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Journal of Energy Chemistry 2022年第5期31卷 548-555页

作者： Xinyan Liu xue-Qiang Zhang xiang Chen Gao-Long Zhu chong Yan Jia-Qi Huang Hong-Jie Peng Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 611731SichuanChina Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China

Estimating battery degradation is vital not only to monitor battery’s state-of-health but also to accelerate research on new battery chemistries. Herein, we present a data-driven approach to forecast the capacity fading trajectory of lab-assembled lithium batteries. Features with physical meanings in addition to predictive abilities are extracted from discharge voltage curves, enabling online prediction for a single cell with only its historical data. The robustness and generalizability allow for the demonstration on a compromised quality dataset consisting of batteries varying in battery architectures and cycling conditions,with superior accuracy for end of life and degradation trajectory prediction with average errors of 8.2%and 2.8%, respectively. Apart from the impressive prediction accuracy, the as-extracted features also provide physical insights, the incorporation of which into material design or battery operation conditions further enlightens the development of better batteries. We highlight the effectiveness of time-seriesbased techniques in forecasting battery cycling performance, as well as the huge potential of datadriven methods in unveiling hidden correlations in complicated energy chemistries such as lithium metal batteries.

关键词： Battery prognosis Machine learning Time series forecasting Online prediction Lithium metal batteries

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Arnold diffusion for nearly integrable Hamiltonian systems

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Science China Mathematics 2023年第8期66卷 1649-1712页

作者： chong-Qing Cheng Jinxin xue School of Mathematical Sciences Nanjing Normal UniversityNanjing210023China Department of Mathematical Sciences Tsinghua UniversityBeijing100084China

In this paper,we prove that the nearly integrable system of the form H(x,y)=h(y)+εP(x,y),x∈T^(n),y∈T^(n),n≥3 admits orbits that pass through any finitely many prescribed small balls on the same energy level H^(-1)(E)provided that E>min h,if h is convex,andεP is *** settles the Arnold diffusion conjecture for convex systems in the smooth *** also prove the counterpart of Arnold diffusion for the Riemannian metric perturbation of the flat torus.

关键词： Arnold diffusion normal form Aubry set normally hyperbolic invariant cylinder cohomological equivalence ladder

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Variational approach to Arnold diffusion

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Science China Mathematics 2019年第11期62卷 2103-2130页

作者： chong-Qing Cheng Jinxin xue Department of Mathematics Nanjing UniverisityNanjing 10009&China Yau Mathematical Sciences Center Tsinghua UniversityBeijing 100084China

Arnold diffusion was conjectured by Arnol’d(1964) as a typical phenomena of topological instability in classical mechanics. In this paper, we give a panorama of the researches on Arnold diffusion using the variationa... 详细信息

关键词： Arnold diffusion Aubry set normal hyperbolicity normal form variational methods genericity

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Is the 0.36keV X-ray a Sign of the Existence of Antimatter Domains ?

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Chinese Physics Letters 1999年第3期16卷 232-234页

作者： XU chong-ming WANG xiang-yu ZHAO Yong-heng WU xue-jun Department of Physics Nanjing Normal UniversityNanjing 210097 Beijing Astronomical Observatory Chinese Academy of SciencesBeijing 100012

If the universe consisted of domains of matter and antimatter,annihilations of e^(+)-e^(-) at the domain interface in the recombination time would leave an imprint on the x-ray band due to the high *** found five ROSAT sources with the 0.36keV spectral line,especially the source lRXP J005510-3738.8 has a single sharp spectral line almost without a continuous *** is hard to be produced by any mechanism except the annihilations of e^(+)-e^(-).

关键词： spectrum. annihilation Existence

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Steering control in autonomous vehicles using deep reinforcement learning

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The Journal of China Universities of Posts and Telecommunications 2018年第6期25卷 58-64,73页

作者： xue chong Jia Peng Zhang Xinyu Department of Computer Science and Technique Tsinghua UniversityBeijing 300401China Joint Logistics College Beijing 100858China

A novel deep reinforcement learning-based steering control method of autonomous vehicles is proposed. A distortionless compressing method of action space is presented. Convolutional neural networks(CNNs) are designed to serve as an action policy. Driver experience is investigated and modeled to optimize policy of new actions exploration. Experimental results show that the proposed algorithm has better robustness and smoothness. Moreover, it is applicable to different roads, velocities or wire-control systems.

关键词： autonomous vehicles deep reinforcement learning steering control CNNs

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