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Malignant peripheral nerve sheath tumor in an elderly patient with superficial spreading melanoma:A case report

World Journal of Clinical Cases 2021年第22期9卷 6457-6463页

作者： chong-Miao Yang Jia-min Li Rui Wang Li-Gong Lu Department of Medical Imaging Zhuhai Hospital Affiliated with Jinan UniversityZhuhai People’s HospitalZhuhai 519000Guangdong ProvinceChina Zhuhai Hospital Affiliated with Jinan University Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Department of Pathology Zhuhai Hospital Affiliated with Jinan UniversityZhuhai People’s HospitalZhuhai 519000Guangdong ProvinceChina Zhuhai Interventional Medical Center Zhuhai Precision Medical CenterZhuhai People’s Hospital of Jinan UniversityZhuhai 519000Guangdong ProvinceChina

BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a type of spindle cell sarcoma originating from the peripheral nerve,which usually results in the corresponding nerve sign on magnetic resonance imaging(MRI).Patients with MPNST may also have neurofibromatosis type *** SUMMARY A 78-year-old male was admitted to the hospital due to a tumor in his left *** had a previous history of superficial spreading melanoma on the left *** Doppler ultrasonography showed a hypoechoic mass in the subcutaneous soft tissues of the medial left knee with an abundant rich blood *** tomography scanning did not show obvious signs of bone destruction,but the skin adjacent to the tumor was slightly *** examination revealed that the hypervascular lesion was well-circumscribed,lobulated,invaded the surrounding soft tissues and demonstrated heterogeneous enhancement but lacked an entering and exiting nerve *** MRI result indicated the invasiveness of the *** patient underwent a left knee joint mass expanded resection and the first histopathological examination showed a MPNST with positive surgical ***,the second extended resection was performed,and the patient had a good outcome in the short *** MRI is a useful technique for revealing the biological characteristics of MPNST and provides clinical support for evaluation of the surgical area before operation.

关键词： Malignant peripheral nerve sheath tumor Superficial spreading melanoma Case report Magnetic resonance imaging Extended resection

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Effects of sediment load on the abrasion of soil aggregate and hydraulic parameters in experimental overland flow

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Journal of Integrative Agriculture 2020年第4期19卷 1117-1126页

作者： WANG Jun-guang YU Bing NI Shi-min GUO Zhong-lu CAI chong-fa Key Laboratory of Arable Land Conservation(Middle and Lower Reaches of Yangtze River) Ministry of Agriculture and Rural Affairs/College of Resources and EnvironmentHuazhong Agricultural UniversityWuhan 430070.P.R.China Hubei Water Resources Research Institute Wuhan 430070.P.R.China

The breakdown of soil aggregates under rainfall and their abrasion in overland flow are important processes in water erosion due to the production of more fine and transportable particles and,the subsequent significant effect on the erosion ***,little is known about the effects of sediment load on the soil aggregate abrasion and the relationship of this abrasion with some related hydraulic ***,the potential effects of sediment load on soil aggregate abrasion and hydraulic parameters in overland flow were investigated through a series of experiments in a 3.8-m-long hydraulic flume at the slope gradients of 8.7 and 26.8%,unit flow discharges from 2×10^-3 to 6×10^-3 m^2 s^-1,and the sediment concentration from 0 to 110 kg *** the aggregates from Ultisols developed Quaternary red clay,Central *** results indicated that discharge had the most significant(P<0.01)effect on the aggregates abrasion with the contributions of 58.76 and 60.34%,followed by sediment feed rate,with contributions of 39.66 and 34.12%at the slope gradients of 8.7 and 26.8%,*** abrasion degree of aggregates was found to increase as a power function of the sediment ***,the flow depth,friction factor,and shear stress increased as a power function along with the increase of sediment concentration at different slope gradients and *** number was obviously affected by sediment concentration and it decreased as sediment concentration *** ratio of the residual weight to the initial weight of soil aggregates(Wr/Wi)was found to increase as the linear function with an increasing flow depth(P=0.008)or Reynolds number(P=0.002)in the sediment-laden *** Wr/Wi values followed a power function decrease with increasing friction factor or shear stress in the sediment-laden flow,indicating that friction factor is the best hydraulic parameter for prediction of soil aggregate abrasion under different sediment load conditio

关键词： soil aggregate sediment load hydraulic parameters overland flow

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Ethanol extract from Gynostemma pentaphyllum ameliorates dopaminergic neuronal cell death in transgenic mice expressing mutant A53T human alpha-synuclein

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Neural Regeneration Research 2020年第2期15卷 361-368页

作者： Hyun Jin Park Ting Ting Zhao Seung Hwan Kim chong Kil Lee Bang Yeon Hwang Kyung Eun Lee Myung koo Lee Department of Pharmacy College of PharmacyChungbuk National UniversityCheongjuRepublic of Korea 2Research Center for Bioresource and Health College of PharmacyChungbuk National UniversityCheongjuRepublic of Korea Department of Social Physical Education Songwon UniversityGwangjuRepublic of Korea

Gynostemma(G.) pentaphyllum(Cucurbitaceae) contains various bioactive gypenosides. Ethanol extract from G. pentaphyllum(GP-EX) has been shown to have ameliorative effects on the death of dopaminergic neurons in animal models of Parkinson’s disease(PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-and 6-hydroxydopamine. PD patients exhibit multiple symptoms, so PD-related research should combine neurotoxin models with genetic models. In the present study, we investigated the ameliorative effects of GP-EX, including gypenosides, on the cell death of dopaminergic neurons in the midbrain of A53 T α-synuclein transgenic mouse models of PD(A53 T). Both GP-EX and gypenosides at 50 mg/kg per day were orally administered to the A53 T mice for 20 weeks.α-Synuclein-immunopositive cells and α-synuclein phosphorylation were increased in the midbrain of A53 T mice, which was reduced following treatment with GP-EX. Treatment with GP-EX modulated the reduced phosphorylation of tyrosine hydroxylase, extracellular signal-regulated kinase(ERK1/2), Bcl-2-associated death promoter(Bad) at Ser112, and c-Jun N-terminal kinase(JNK1/2) due to α-synuclein overexpression. In the A53 T group, GP-EX treatment prolonged the latency of the step-through passive avoidance test and shortened the transfer latency of the elevated plus maze test. Gypenosides treatment exhibited the effects and efficacy similar to those of GP-EX. Taken together, GP-EX, including gypenosides, has ameliorative effects on dopaminergic neuronal cell death due to the overexpression of α-synuclein by modulating ERK1/2, Bad at Ser112, and JNK1/2 signaling in the midbrain of A53 T mouse model of PD. Further studies are needed to investigate GP-EX as a treatment for neurodegenerative synucleinopathies, including PD. This study was approved by the Animal Ethics Committee of Chungbuk National University(approval No. CBNUA-956-16-01) on September 21, 2016.

关键词： A53T α-synuclein genetic mice ERK1/2 gynostemma pentaphyllum gypenosides Parkinson’s disease retention transfer latency time

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基于云模型的零碳高速公路综合性能评价体系

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公路 2024年第5期69卷 285-294页

作者：师瑞峰刘根茂孙周陈冲赵天宇贾利民华北电力大学控制与计算工程学院北京市102206 华北电力大学国家能源交通融合发展研究院北京市102206 四川蜀道清洁能源集团有限公司成都市610041 北京能高自动化技术股份有限公司北京市100044 北京交通大学轨道交通控制与安全国家重点实验室北京市100044

发展零碳高速公路是解决公路交通绿色化、智能化转型及实现公路交通“双碳目标”的必由之路。系统调研并梳理了既有低碳、零碳高速公路的相关现状,提出了零碳高速公路的建设内涵,构建了包括资源节约、生态保护、技术创新、智慧交通、服... 详细信息

发展零碳高速公路是解决公路交通绿色化、智能化转型及实现公路交通“双碳目标”的必由之路。系统调研并梳理了既有低碳、零碳高速公路的相关现状,提出了零碳高速公路的建设内涵,构建了包括资源节约、生态保护、技术创新、智慧交通、服务共享、教育示范等6个方面在内的零碳高速公路评价指标体系,形成了基于层次分析法与熵权法组合赋权法确定指标权重、基于最大隶属度可拓云模型的零碳高速公路定级评价方法。以攀大高速公路为例,对上述评价体系进行案例验证,研究结果表明,所构建的指标体系全面合理,评价方法简单易行,验证了该指标体系的合理性与实用性。

关键词：零碳高速公路零碳等级评价正态云模型层次分析法熵权法

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Effect of Cu seed on the synthesis and characterization of FeCo alloy nano-particles by using polyol method

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Science China(Technological Sciences) 2009年第1期52卷 19-22页

作者： Uk Rae CHO Young min LEE Shalendra KUMAR Chan Gyu LEE Bon Heun koo School of Nano-Advanced Materials Engineering Changwon National University Changwon

Fine metal particles with uniform shape, narrow size distribution and high purity are increasingly needed for specific uses in high tech industrial application. We report the direct chemical synthesis of FeCo alloy particles using the mixture of FeCl2·4H2O, Co (Ac)2·4H2O (Ac: acetate) and NaOH in ethylene glycol, and then obtained FeCo alloy particles better dispersed by adding the polyvinylpyrrolidone (PVP) and also the size could be controlled by adding copper. The prepared nano-particles were characterized using FESEM, XRD and VSM. The mean diameter of these particles was varied in the range of sub- mi- crometer to nanometer with metal-ion concentration. FeCo particles showed the typical soft magnetic properties.

关键词： polyol method FeCo alloy nanoparticle Cu seed soft magnetic

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Static and dynamic evolution of CO adsorption onγ-U(100)surface with different levels of Mo doping using DFT and AIMD calculations

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Nuclear Science and Techniques 2023年第9期34卷 142-154页

作者： Jun-Wei Li Wei-min Jia chong Liu Sha-Sha Lv Jin-Tao Wang Zheng-Cao Li Key Lab of Advanced Materials(MOE) School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Xi’an Research Institute of High-Technology Xi’an 710025China Key Laboratory of Beam Technology(MOE) College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China

Alloys of uranium and molybdenum are considered as the future of nuclear fuel and defense ***,surface corrosion is a fundamental problem in practical applications and *** this study,the static and dynamic evolution of carbon monoxide(CO)adsorption and dissociation onγ-U(100)surface with different Mo doping levels was investigated based on density functional theory and ab initio molecular *** the static calculation phase,parameters,such as adsorption energy,configuration,and Bader charge,were evaluated at all adsorption ***,the time-dependent behavior of CO molecule adsorption were investigated at the most favorable *** minimum energy paths for CO molecu-lar dissociation and atom migration were investigated using the transition state search *** results demonstrated that the CO on the uranium surface mainly manifests as chemical adsorption before dissociation of the CO *** CO molecule exhibited a tendency to rotate and tilt upright ***,it is difficult for CO adsorption on the surface in one of the configurations with CO molecule in vertical direction but oxygen(O)is closer to the *** charge illustrates that the charge transfers from slab atoms to the 2π*antibonding orbital of CO molecule and particularly occurs in carbon(C)*** time is less than 100 fs for the adsorptions that forms embryos with tilt upright in dynamics *** density of states elucidates that the overlapping hybridization of C and O 2p orbitals is mainly formed via the d orbitals of uranium and molybdenum(Mo)atoms in the dissociation and re-adsorption of CO *** conclusion,Mo doping of the surface can decelerate the adsorption and dissociation of CO molecules.A Mo-doped surface,created through ion injection,enhanced the resistance to uranium-induced surface corrosion.

关键词： Adsorption and dissociation Uranium CO molecule Density functional theory Ab initio molecular dynamics

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An Efficient Approach for Mitigating Covert Storage Channel Attacks in Virtual Machines by the Anti-Detection Criterion

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Journal of Computer Science & Technology 2019年第6期34卷 1351-1365页

作者： chong Wang Nasro min-Allah Bei Guan Yu-Qi Lin Jing-Zheng Wu Yong-Ji Wang Institute of Software Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China College of Computer Science and Information Technology Imam Abdulrahman Bin Faisal UniversityDammam 1982 Saudi Arabia Block Chain Research Center Blue HelixGrand Cayman KY1-1100Cayman Islands

Covert channels have been an effective means for leaking confidential information across security domains and numerous studies are available on typical covert channels attacks and *** covert channel threat restriction solutions are based on the threat estimation criteria of covert channels such as capacity,accuracy,and short messages which are effective in evaluating the information transmission ability of a covert(storage)***,these criteria cannot comprehensively reflect the key factors in the communication process such as shared resources and synchronization and therefore are unable to evaluate covertness and complexity of increasingly upgraded covert storage *** a solution,the anti-detection criterion was introduced to eliminate these limitations of cover *** effective,most threat restriction techniques inevitably incur high performance overhead and hence become *** this work,we avoid such overheads and present a restriction algorithm based on the anti-detection criterion to restrict threats that are associated with covert storage channels in virtual machines while maintaining the resource efficiency of the *** evaluation shows that our proposed solution is able to counter covert storage channel attacks in an effective *** with Pump,a well-known traditional restriction algorithm used in practical systems,our solution significantly reduces the system overhead.

关键词： covert storage channel information security covert channel threat evaluation security and privacy protection

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Relation of tea ingestion to salivary redox and flow rate in healthy subjects

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Food Science and Human Wellness 2023年第6期12卷 2336-2343页

作者： Pik Han chong Qiaojuan He Suyun Zhang Jianwu Zhou Pingfan Rao min Zhang Lijing Ke Zhejiang Gongshang University Joint Centre for Food and Nutrition Sciences Zhejiang Gongshang UniversityHangzhou 310018China Institute of Food Science Jishou UniversityJishou 416000China

The biochemistry of human saliva can be altered by food *** benefits of tea drinking were extensively studied but the influence of tea ingestion on human saliva has not been *** work aimed to investigate the immediate and delayed effect of vine tea,oolong tea and black tea intake on certain salivary biochemistry and flow *** saliva samples of healthy subjects were collected before,after and 30 min after tea *** chemical compositions and antioxidant capacity of tea samples were analyzed to correlate with salivary *** component analysis indicated that the effects of vine tea consumption were dominated by increasing salivary flow rate(SFR),production rate of total protein(TPC),thiol(SH),malondialdehyde,catalase activity and antioxidant capacity(FRAP)in *** antioxidant profile of studied tea samples(FRAP,polyphenols,flavonoids)was positively correlated with salivary SFR,TPC,SH and FRAP but negatively correlated with salivary uric acid concentration in saliva.

关键词： Black tea Flow rate Oolong tea Salivary redox status Vine tea

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机构伦理审查信息化管理系统的建设与实践

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中国医学伦理学 2024年第2期37卷 219-223页

作者：张露远李翀邓志勇李红英朱晓旭陈旻吕维玲周蓦江苏大学附属昆山市第一人民医院伦理办公室江苏昆山215300 苏州大学附属第一医院科技处/伦理办公室江苏苏州215006 苏州大学计算机科学与技术学院江苏苏州215000 福建医科大学卫生管理学院福建福州350122 河南大学淮河医院伦理办公室河南开封475000 苏州市立医院本部伦理办公室江苏苏州215000

随着社会进步,科技研发活动全球化发展,医疗机构伦理委员会审查项目日益增多,电子信息化的建设及管理显得异常重要。在机构伦理审查电子信息化建设的过程中应基于科技伦理治理的新政策,考虑机构伦理委员会的制度和标准操作规程,并结合... 详细信息

随着社会进步,科技研发活动全球化发展,医疗机构伦理委员会审查项目日益增多,电子信息化的建设及管理显得异常重要。在机构伦理审查电子信息化建设的过程中应基于科技伦理治理的新政策,考虑机构伦理委员会的制度和标准操作规程,并结合工作实际制定合理的流程,简化人工操作,提高项目管理的准确性,做到精细化管理,方便研究者、伦理委员会秘书及委员的沟通交流。

关键词：机构伦理委员会伦理审查信息化科技伦理治理

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空间信息技术在土壤重金属污染研究中的应用

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环境卫生学杂志 2024年第6期14卷 520-527页

作者：田迎赵玉敏种世桂赵宇馨桂林医学院公共卫生学院桂林541000 甘肃医学院

空间信息技术发展迅速,在环境保护和环境污染防治方面应用前景广阔。土壤重金属污染对人体健康和生态平衡的影响十分严重,是中国相当重视的环境问题。利用空间信息技术,可以获取土壤重金属的含量、空间分布、来源等相关信息,对于开展土... 详细信息

空间信息技术发展迅速,在环境保护和环境污染防治方面应用前景广阔。土壤重金属污染对人体健康和生态平衡的影响十分严重,是中国相当重视的环境问题。利用空间信息技术,可以获取土壤重金属的含量、空间分布、来源等相关信息,对于开展土壤环境风险评估、污染治理、长期监测等工作具有重要意义。本文综述空间信息技术在土壤重金属污染研究中的应用。

关键词：空间信息技术重金属土壤污染

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