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Impact of Diabetes Mellitus on the Treatment Outcomes of Chemotherapy in Women with Breast Cancer——A Population-Based Prospective Cohort Study

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Journal of Electronic Science and Technology 2015年第1期13卷 87-93页

作者： yu-ching chen cheng-Wei Chang Jorng-Tzong Horng Yan-Jun chen Jin-Tsung Yang Department of Bioinformatics Asia University Department of Information Management Hsing Wu University Department of Computer Science and Information Engineering National Central University Office of Physical Education National Central University

There are few population-based data in investigating the impact of diabetes on chemotherapy adverse effects and treatment outcomes of non-metastatic breast cancer. The purpose of this study is to evaluate whether diabetes affects the patterns of use in chemotherapy, toxic effects of chemotherapy, and treatment outcomes for non-metastatic breast cancer in Taiwan. The study results can provide physicians for making a decision whether or not to use chemotherapy based on the individual patients＇ condition.

关键词： Chemotherapy diabetes mellitus national insurance research database non-metastatic breast cancer population-based study

Heat Transfer Characteristics of a Microchannel Heat Sink with Highly-Dense Micro-Jet Arrays

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Journal of Thermal Science 2024年第3期33卷 1148-1160页

作者： ZHANG yu chen Xiaoyan MIAO Lin chen Liang HOU yu State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an710049China Beijing Aerospace Technology Institute Beijing100083China

This paper proposed a new structure of highly-dense micro-jet arrays for hybrid jet-impingement/microchannel heat sinks(~120 jet per cm^(2) with jet width of 0.35 mm).Parametric study is performed to investigate the influence of structure and flow parameters on the convective heat transfer of water jet cooling in confined *** simulation results show that the optimal jet width,jet spacing and impingement distance are around 0.2 mm,0.2 mm and 0.3 mm,respectively,which can achieve a low thermal resistance as well as a relatively low pressure *** analysis of the heat transfer pathways shows that the micro-fin jet structures can extend the impinging heat transfer area and conduct a considerable proportion of heat,which can reach up to 38.9%with the Reynolds number ranging from 797.1 to *** heat transfer characteristics in the heat sink will shift from impingement dominated heat transfer to the channel-convection dominated heat transfer as the jet impingement distance increases.A correlation is proposed to predict the average Nusselt number on the stagnation area for the heat sink with different structure parameters,and the deviations of predictions from the numerical results are less than 10%.

关键词： hybrid heat sink impingement microchannel thermal management high heat flux

Approximate analytical solutions for threedimensional ascent trajectory of a solid-fuel launch vehicle with time-varying mass flow rate

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Chinese Journal of Aeronautics 2024年第10期37卷 275-293页

作者： Qi yu Wanchun chen Wenbin yu School of Astronautics Beihang UniversityBeijing 102206China

In the scenario that a solid-fuel launch vehicle maneuvers in outer space at high angles of attack and sideslip for energy management,Approximate Analytical Solutions(AAS)for the threedimensional(3D)ascent flight states are derived,which are the only solutions capable of considering time-varying Mass Flow Rate(MFR)at *** uneven MFR makes the thrust vary nonlinearly and thus increases the difficulty of the problem *** AAS are derived based on a 3D Generalized Ascent Dynamics Model(GADM)with a normalized mass as the independent *** simplify some highly nonlinear terms in the GADM,several approximate functions are introduced carefully,while the errors of the approximations relative to the original terms are regarded as minor ***,a finite series with positive and negative exponents,called Exponent-Symmetry Series(ESS),is proposed for function approximation to decrease the highest exponent in the AAS so as to reduce computer round-off *** calculate the ESS coefficients,a method of seeking the Optimal Interpolation Points(OIP)is proposed using the leastsquares-approximation *** to the artful design of the approximations,the GADM can be decomposed into two analytically solvable subsystems by a perturbation method,and thus the AAS are obtained ***,to help implement the AAS,two indirect methods for measuring the remaining mass and predicting the burnout time in flight are put forward using information from *** results verify the superiority of the AAS under the condition of time-varying MFR.

关键词： Approximate analytical solutions 3D ascent trajectory Solid-fuel launch vehicle Uneven thrust Energy management

Low-melting mixture solvents: extension of deep eutectic solvents and ionic liquids for broadening green solvents and green chemistry

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Green Chemical Engineering 2024年第4期5卷 409-417页

作者： yu chen Zhiwu yu MOE Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology Department of ChemistryTsinghua University

Green solvents such as water and ionic liquids(ILs) are pillars of the great mansion of green chemistry and green processing. Initially proposed as a new family of ILs,deep eutectic solvents(DESs) have received fast development in the past two decades. In this contribution,DESs are reviewed critically and the concept is extended to lowmelting mixture solvents(Lo MMSs),which cover all kinds of materials including ionic compounds,molecular compounds,and metals. Six classes of Lo MMSs are proposed as the new classification system and examples are given. Finally,several thermodynamic issues concerning Lo MMSs are discussed. Two new concepts,robustness of Lo MMSs and high-entropy Lo MMSs,are proposed.

关键词： Green solvents Deep eutectic solvents Low transition temperature mixture solvents Phase diagram EGaIn

Atomically Dispersed Ruthenium Catalysts with Open Hollow Structure for Lithium-Oxygen Batteries

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Nano-Micro Letters 2024年第2期16卷 154-164页

作者： Xin chen yu Zhang Chang chen Huinan Li yuran Lin Ke yu Caiyun Nan chen chen Beijing Advanced Innovation Center for Materials Genome Engineering Institute of Solid State ChemistryUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China Engineering Research Center of Advanced Rare Earth Materials Department of ChemistryTsinghua UniversityBeijing 100084People’s Republic of China Beijing Key Laboratory of Energy Conversion and Storage Materials Institution College of ChemistryBeijing Normal UniversityBeijing 100875People’s Republic of China

Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at ***,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen *** one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox *** the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic ***,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery.

关键词： Atomically dispersed Open hollow structure Discharge product Lithium Oxygen battery

State-of-the-art on the anchorage performance of rock bolts subjected to shear load

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International Journal of Coal Science & Technology 2024年第1期11卷 1-30页

作者： yu chen Haodong Xiao School of Civil Engineering Sun Yat-sen UniversityZhuhai519082China

Rock bolts are extensively utilized in underground engineering as a means of offering support and stability to rock masses in tunnels,mines,and other underground *** environments of high ground stress,faults or weak zones can frequently arise in rock formations,presenting a significant challenge for engineering and potentially leading to underground engineering *** bolts serve as a crucial structural element for the transmission of tensile stress and are capable of withstanding shear loads to prevent sliding of weak zones within rock ***,a complete understanding of the behavior of rock bolts subjected to shear loads is *** paper presents a state-of-the-art review of the research progress of rock bolts subjected to shear load in three categories:experiment,numerical simulation,and analytical *** review focuses on the research studies and developments in this area since the 1970s,providing a comprehensive overview of numerous factors that influence the anchorage performance of rock *** factors include the diameter and angle of the rock bolt installation,rock strength,grouting material,bolt material,borehole diameter,rock bolt preload,normal stress,joint surface roughness and joint expansion *** paper reviews the improvement of mechanical parameter setting in numerical simulation of rock bolt ***,it delves into the optimization of the analytical model concerning rock bolt shear theory,approached from the perspectives of both Elastic foundation beam theory coupled with Elastoplasticity theory and Structural mechanic *** significance of this review lies in its ability to provide insights into the mechanical behavior of rock *** paper also highlights the limitations of current research and guidelines for further research of rock bolts.

关键词： Rock bolt Shear load Shear test Numerical simulation Analytical model

Mott insulator-density ordered superfluid transition and‘shamrock transition’in a frustrated triangle lattice

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Communications in Theoretical Physics 2024年第3期76卷 157-164页

作者： Ce Wang yu chen School of Physics Science and Engineering Tongji UniversityShanghai200092China Institute for Advanced Study Tsinghua UniversityBeijing100084China Graduate School of China Academy of Engineering Physics Beijing100193China

Density order is usually a consequence of the competition between long-range and short-range *** we report a density ordered superfluid emergent from a homogeneous Mott insulator due to the competition between frustrations and local *** transition is found in a Bose–Hubbard model on a frustrated triangle lattice with an extra pairing ***,we find a quantum phase transition between two different density ordered superfluids,which is beyond the Landau–Ginzburg(LG)paradigm.A U(1)symmetry is emergent at the critical point,while the symmetry in each density ordered superfluid is Z_(2)×Z_(3).We call the transition a‘shamrock transition’,due to its degenerate ground state in the parameter space being a shamrock-like curve rather than a circle in an LG-type *** low energy theories are established for the two transitions mentioned above and we find their resemblance and differences with clock models.

关键词： frustrated magnets superfluid mott insulator density wave ordered phase clock model

Cooperative game penetration guidance for multiple hypersonic vehicles under safety critical framework

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Chinese Journal of Aeronautics 2024年第1期37卷 247-255页

作者： Jieqing chen Ruisheng SUN yu LU School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing 210094China

The rapid development of the anti-missile weapon technology brings new challenges to the cooperative penetration strategy solution and the guidance law design for Hypersonic Vehicles(HVs).This paper studies the coordinated game penetration guidance problem for multiple hypersonic vehicles faced with space threat areas.A scheme for seeking cooperative game penetration guidance strategy under safety critical control framework is *** this scheme,a multiHV cooperative game model is proposed in a minimum optimization form which can simplify the solving process and accelerate the computing ***,a second-order control barrier function is developed to transform the implicit nonlinear constraints of the proposed model into linear *** order to obtain better performance of guidance strategy,a composite guidance law under the safety critical control framework is presented to allocate guidance strategies appropriately in the whole *** is shown that the proposed scheme can guarantee successful penetration while avoiding threat ***,a comparative simulation with a two-on-three game is conducted to verify the effectiveness of the proposed method.

关键词： Hypersonic vehicles Safety critical control Penetration game Space constraints Cooperative guidance

Design and Gait Planning of a Worm-inspired Metameric Robot for Pipe Crawling

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Journal of Bionic Engineering 2024年第3期21卷 1265-1277页

作者： yu Liu Qingbiao Shi Zhen chen Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen361102China

The earthworm has been attracted much attention in the research and development of biomimetic robots due to their unique locomotion mechanism,compact structure,and small motion *** paper presents a new design and prototype of a worm-inspired metameric robot with a movement pattern similar to that of *** robot consists of multiple telescopic modules connected in series through joint *** telescopic module mimics the contraction and elongation motion modes of the earthworm segments.A kinematic and dynamic analysis is conducted on the telescopic module,and an input torque calculation method is provided to ensure sufficient friction between the robot and the pipe *** gait modes of the prototype robot for straight and turning locomotion are introduced,and these modes are extended to robots constructed by different numbers of telescopic *** addition,a method is proposed to increase the friction between the robot and the pipe wall in the aforementioned gait modes without changing the robot structure,thereby improving the robot’s motion ability in *** theoretical model of gait modes has also been validated through gait *** findings of this paper would provide a useful basis for the design,modeling,and control of future worm inspired robots.

关键词： Bio-inspired robot Spatial linkage mechanism Kinematics model Peristaltic locomotion