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Children’s Health, Parent-Child Activities, Using Digital Devices, and Social Competence: Serial Mediation

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Health 2023年第8期15卷 883-894页

作者： ching-Fen Lee Shain-May tang Department of Early Childhood Education and Care Minghsin University of Science and Technology Hsinchu Department of Living Science National Open University New Taipei City

Background: Studies have pointed out the influence of different children’s activities and prolonged use of digital products on their social development. However, whether the parent-child activities and using digital devices were serial mediators of the relationship between children’s health and social development needs further verification. Purpose: This study explored how parent-child activities and children’s use of digital devices influence the relationship between children’s health and their social competence. Method: This study used data from Kids in Taiwan: National Longitudinal Study of Child Development and Care. A total sample of 2164 participants was used in this study. Serial mediation analyses were performed using model six of Hayes’ PROCESS (2012). Results: This study found that parent-child activities and the use of digital devices can serially mediate the relationship between children’s health and social competence. Children’s health could directly improve their social competence, but it could also serially mediate social competence by increasing parent-child activities and reducing the use of digital devices. Conclusion: Childcare policy planners and parenting educators should not only call on parents to reduce the use of electronic products for their children, but also encourage parents to spend more time interacting with their children, so that children can learn social skills by interacting with others in their daily lives.

关键词： Children’s Health Social Competence Parent-Child Activities Using Digital Devices Preschooler

The Moderating Effect of Health on the Relationship between Involvement in Housework of Parents’ and Parents-in-Law’s Families and Happiness of Middle-Aged Women in Taiwan

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Health 2020年第9期12卷 1217-1240页

作者： ching-Fen Lee Shain-May tang Department of Early Childhood Educare Ching Kuo Institute of Management & Health Taiwan Department of Living Science National Open University Taiwan

Background: This study aims to investigate the moderating effect of family health status on the relationship between involvement in housework of two-side parents’ families and happiness of middle-aged women in Taiwan. Methods: The data used in this study were gathered from the Ministry of Science and Technology’s program—“Intergenerational expectation and collaboration: an inquiry on a new mechanism of continued tradition across generations”. The subjects (n = 512) were restricted to aged 45 - 64 years old who live with spouses and have children, and one of whose parent or parent-in-law is still alive. Multiple regression analysis was used to investigate how family health status moderates the relationship between involvement in housework of parents’ families and parents-in-law’s families and the happiness of middle-aged women. Results: 1) Family health status is positively correlated with their happiness. 2) The parents’ health status can moderate the relationship between involvement in housework of parents’ families and happiness of the middle-aged women. 3) The middle-aged women’s health status can moderate the relationship between involvement in housework of parents-in-law’s families and those women’s happiness, and fathers-in-law’s health status can moderate the relationship between husbands’ involvement in housework of the women’s parents-in-law’s families and women’s happiness. Conclusions: In future, when policies and programs related to the well-being of middle-aged women are being planned, the effect of women’s health and family health status shall be considered as a key to improve those women’s quality of life.

关键词： Middle-Aged Women Intergenerational Support Housework Family Health Happiness

Investigation of a Pressure Sensor with Temperature Compensation Using Two Concentric Wheatstone-Bridge Circuits

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Modern Mechanical Engineering 2013年第2期3卷 104-113页

作者： Chi-Chang hsieh Chih-ching Hung Yan-Huei Li Department of Mechanical and Automation Engineering National Kaohsiung First University of Science and Technology Taiwan Department of Product Design Shu-Te University Taiwan

This study presents a silicon-based pressure sensor with temperature compensation. The eight piezoresistors were designed on the polycrystalline silicon membrane and constructed by two concentric Wheatstone-bridge circuits to perform two sets of sensors. The sensor in the central circuit measures the membrane deflection caused by the combined effects of pressure and temperature, while the outer one measures only the deflection caused by the working temperature. From this arrangement, it is reliable and accurate to measure the pressure by comparing the output signals from the two concentric Wheatstone-bridge circuits. The optimal positions of the eight piezoresistors were simulated by simulation software ANSYS. The investigated pressure sensor was fabricated by the micro electro-mechanical systems (MEMS) techniques. The measuring performance and an indication of the conventional single Wheatstone-bridge pressure sensor is easily affected under variation of different working temperature and causes a maximum absolute error up to 45.5%, while the double Wheatstone-bridge pressure sensor is able to compensate the error, and reduces it down to 1.13%. The results in this paper demonstrate an effective temperature compensation performance, and have a great performance and stability in the pressure measuring system as well.

关键词： Pressure Sensor Temperature Compensation Wheatstone-Bridge Circuit MEMS

Inhibition of citrus flavonoids on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumorigenesis in mice

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Food Science and Human Wellness 2012年第1期1卷 65-73页

作者： Min-Hsiung Pan Shiming Li ching-Shu Lai Yutaka Miyauchi Michiko Suzawa Chi-tang Ho Department of Seafood Science National Kaohsiung Marine UniversityKaohsiung 811TaiwanChina Department of Food Science Rutgers UniversityNew BrunswickNJ 08901USA Miyauchi Citrus Research Center 324-10 Shigoka-MachiTakasakiGunma 370-0845Japan

The inhibitory effects of a formulated product from citrus peel extract,Gold Lotion(GL),on 12-O-tetradecanoylphorbol 13-acetate(TPA)-induced expression of inducible nitric oxide synthase(iNOS)and cyclooxygenase-2(COX-2)in mouse skin was reported in this *** is found that in the TPA-induced skin inflammation model,the topical application of GL effectively inhibited the transcriptional activation of iNOS and its mRNA and protein in mouse *** is also discovered that GL significantly inhibited TPA-induced mouse skin inflammation by decreasing inflammatory gene ***,GL dramatically inhibited 7,12-dimethylbenez[a]anthracene(DMBA)/TPA-induced skin tumor formation and reduced tumor incidence,tumor weight and tumor multiplicity of papillomas at 20 *** essence,these in vivo data have revealed that GL is an effective anti-tumor agent that functions by down-regulating the protein levels of COX-2,ornithine decarboxylase(ODC),and vascular endothelial growth factor(VEGF)in mouse skin,suggesting that GL is a novel functional natural product capable of preventing inflammation-associated tumorigenesis.©2012 Production and hosting by Elsevier *** behalf of Beijing Academy of Food Sciences.

关键词： Inhibition Skin cancer Citrus flavonoids Inflammation Tumorigenesis

Applying Prim’s Algorithm to Identify Isolated Areas for Natural Disaster Prevention and Protection

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Engineering（科研） 2018年第7期10卷 417-431页

作者： Wen-ching Wang Ming-Che hsieh Chun-Hsiang Huang Department of Information Science and Management Systems National Taitung University Taiwan

Based on the principle of “pre-disaster prevention outweighs rescue during disasters”, this study targets areas threatened by natural disasters, and develops an automatic algorithm based on the Prim algorithm to serve as an automatic identification system. In the face of natural disasters that disable key facilities in the region and prevent settlements from contacting the outside world or outsiders from sending rescuers to the settlements, the proposed system helps to identify whether these regions will become isolated areas and conduct disaster mitigation and relief resource allocation before any natural disaster in order to reduce potential disaster losses. An automatic identification system, based on the threshold of channel blocking due to broken roads and bridges, determines through the decision tree model and relevant patterns whether such regions will become isolated areas by identifying areas based on the results of model analysis. The proposed system’s identification results are verified by actual case histories and comparisons;the results can be used to correctly identify isolated areas. Finally, Microsoft Visual Studio C # and Google Map are employed to apply the results and to produce an information mode for the determination and decision support of isolated areas affected by natural disasters.

关键词： Prim Algorithm Comb Route Isolation Area Hazard Decision Support System

Premedication with pronase or N-acetylcysteine improves visibility during gastroendoscopy: An endoscopist-blinded, prospective, randomized study

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World Journal of Gastroenterology 2007年第3期13卷 444-447页

作者： Chun-Chao Chang Sheng-Hsuan Chen Chih-Ping Lin ching-Ruey hsieh Horng-Yuan Lou Fat-Moon Suk Shiann Pan Ming-Shun Wu Jun-Nan Chen Yung-Fa Chen Division of Gastroenterology Department of Internal Medicine Taipei Medical University Hospital Digestive Disease Research Center Taipei Medical University Taipei Taiwan China Department of Internal Medicine Min-Sheng General Hospital Taoyuan Taiwan China Taipei Medical University-Municipal Wan-Fang Hospital Taipei Taiwan China

AIM： To assess the efficacy of premedicaton with pronase or N-acetylcysteine （NAC） at 20 min before upper gastrointestinal （UGI） endoscopy and to determine whether pronase or NAC pretreatment influences the reliability of the rapid urease test. METHODS： A total of 146 patients were prospectively and randomly assigned into the study groups according to different premedications before endoscopy. One endoscopist assessed mucosal visibility （MV） with scores ranged from 1 to 4 at four sites in the stomach. The sum of the MV scores from these four locations was defined as the total mucosal visibility （TMV） score. Identification of Hpylori was performed using CLO test, histology, and serology. RESULTS： The Group with pronase premedication had a significantly lower TMV score than did the groups with gascon and gascon water （P 〈 0.001 and P 〈 0.01, respectively）. The group with NAC had a significantly lower TMV score than the group with gascon （P 〈 0.01） and a trend of a lower MV score than the group with gascon water （P = 0.06）. The THV score did not significantly differ between the group with pronase and the group with NAC （P = 0.39 and P = 0.14, respectively）. The sensitivity and specifidty of the CLO test were 92.5% and 93.9%, respectively, in groups premedicated with pronase and NAC together.CONCLUSION： Premedication with pronase or NAC at 20 min before UGI endoscopy improves the mucosal visibility of the stomach. Neither pronase nor NAC produces any obvious interference with the CLO test for the identification of H pylori infection.

关键词： Pronase N-acetylcysteine H pylori Gastrointestinal endoscopy

Poorly expandable common bile duct with stones on endoscopic retrograde cholangiography

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World Journal of Gastroenterology 2012年第19期18卷 2396-2401页

作者： Chi-Liang Cheng Yung-Kuan Tsou Cheng-Hui Lin Jui-Hsiang tang hien-Fu Hung Kai-Feng Sung ching-Song Lee Nai-Jen Liu Division of Therapeutic Endoscopy Department of Gas-troenterology and Hepatology Chang Gung Memorial HospitalCollege of Medicine Chang Gung University Taoyuan 333Taiwan China Division of Radiology Department of Gastro-enterology and Hepatology College of Medicine Chang GungUniversity Taoyuan 333 Taiwan China

AIM： To describe characteristics of a poorly expandable （PE） common bile duct （CBD） with stones on en- doscopic retrograde cholangiography.METHODS： APE bile duct was characterized by a rigid and relatively narrowed distal CBD with retro- grade dilatation of the non-PE segment. Between 2003 and 2006, endoscopic retrograde cholangiography （ERC） images and chart reviews of 1213 patients with newly diagnosed CBD stones were obtained from the computer database of Therapeutic Endoscopic Centerin Chang Gung Memoria acteristic PE bile duct on Hospital. Patients with char ERC were identified from the database. Data of the patients as well as the safety and technical success of therapeutic ERC were collected and analyzed retrospectively.RESULTS： A total of 30 patients with CBD stones and characteristic PE segments were enrolled in this study. The median patient age was 45 years （range, 20 to 92 years）; 66.7% of the patients were men. The di ameters of the widest non-PE CBD segment, the PE segment, and the largest stone were 14.3 ± 4.9 mm, 5.8±1.6 mm, and 11.2±4.7 mm, respectively. The length of the PE segment was 39.7±15.4 mm （range, 12.3 mm to 70.9 mm）. To remove the CBD stone（s） completely, mechanical lithotripsy was required in 25 （83.3%） patients even though the stone size was not as large as were the difficult stones that have been described in the literature. The stone size and stone/ PE segment diameter ratio were associated with the need for lithotripsy. Post-ERC complications occurred in 4 cases： pancreatitis in 1, cholangitis in 2, and an im- pacted Dormia basket with cholangitis in 1. Two （6.7%） of the 28 patients developed recurrent CBD stones at follow-up （50±14 mo） and were successfully managed with therapeutic ERC.CONCLUSION： Patients with a PE duct frequently require mechanical lithotripsy for stones extraction, To retrieve stones successfully and avoid complications, these patients should be identified during ERC,

关键词： Common bile duct stone Difficult stone Endoscopic retrograde cholangiography Mechanicallithotripsy

Outreach onsite treatment with a simplified pangenotypic directacting anti-viral regimen for hepatitis C virus micro-elimination in a prison

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World Journal of Gastroenterology 2022年第2期28卷 263-274页

作者： Chun-Ting Chen Ming-Ying Lu Meng-Hsuan hsieh Pei-Chien Tsai Tsai-Yuan hsieh Ming-Lun Yeh ching-I Huang Yi-Shan Tsai Yu-Min Ko ching-Chih Lin Kuan-Yu Chen Yu-Ju Wei Po-Yao Hsu Cheng-Ting Hsu Tyng-Yuan Jang Ta-Wei Liu Po-Cheng Liang Ming-Yen hsieh Zu-Yau Lin Chung-Feng Huang Jee-Fu Huang Chia-Yen Dai Wan-Long Chuang Yu-Lueng Shih Ming-Lung Yu Division of Gastroenterology and Hepatology Department of Internal MedicineTri-Service General Hospital Penghu BranchNational Defense Medical CenterPenghu County 88041Taiwan Division of Gastroenterology and Hepatology Department of Internal MedicineTri-Service General HospitalNational Defense Medical CenterTaipei 11490Taiwan Division of Hepatobiliary Department of Internal Medicine and Hepatitis CenterKaohsiung Medical University HospitalKaohsiung 80708Taiwan School of Medicine and Hepatitis Research Center College of Medicineand Center for Liquid Biopsy and Cohort ResearchKaohsiung Medical UniversityKaohsiung 80708Taiwan National Pingtung University of Science and Technology Pingtung 912Taiwan

BACKGROUND Prisoners are at risk of hepatitis C virus(HCV)infection,especially among the people who inject drugs(PWID).We implemented an outreach strategy in combination with universal mass screening and immediate onsite treatment with a simplified pan-genotypic direct-acting antivirals(DAA)regimen,12 wk of sofosbuvir/velpatasvir,in a PWID-dominant prison in *** To implement an outreach strategy in combination with universal mass screening and immediate onsite treatment with a simplified pan-genotypic DAA regimen in a PWID-dominant prison in *** HCV-viremic patients were recruited for onsite treatment program for HCV micro-elimination with a pangenotypic DAA regimen,12 wk of sofosbuvir/velpatasvir,from two cohorts in Penghu Prison,either identified by mass screen or in outpatient clinics,in September *** group of HCV-viremic patients identified sporadically in outpatient clinics before mass screening were enrolled as a control *** primary endpoint was sustained virological response(SVR12,defined as undetectable HCV ribonucleic acid(RNA)12 wk after end-of-treatment).RESULTS A total of 212 HCV-viremic subjects were recruited for HCV micro-elimination campaign;91 patients treated with sofosbuvir/Ledipasvir or glecaprevir/pibrentasvir before mass screening were enrolled as a *** HCV microelimination group had significantly lower proportion of diabetes,hypertension,hyperlipidemia,advanced fibrosis and chronic kidney diseases,but higher levels of HCV *** SVR12 rate was comparable between the HCV microelimination and control groups,95.8%(203/212)vs 94.5%(86/91),respectively,in intent-to-treat analysis,and 100%(203/203)vs 98.9%(86/87),respectively,in perprotocol *** was no virological failure,treatment discontinuation,and serious adverse event among sofosbuvir/velpatasvir-treated patients in the HCV micro-elimination *** Outreach mass screening followed by immediate onsite treatment with a simplified pange

关键词： Direct-acting antivirals Sofosbuvir Velpatasvir People who inject drugs Universal screen

Black tea in chemo-prevention of cancer and other human diseases

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Food Science and Human Wellness 2013年第1期2卷 12-21页

作者： Min-Hsiung Pan ching-Shu Lai Hong Wang Chih-Yu Lo Chi-tang Ho Shiming Li Department of Seafood Science National Kaohsiung Marine UniversityKaohsiung 811TaiwanChina Shaklee Corporation 4747 Willow RoadPleasantonCA 94588USA Department of Food Science National Chiayi UniversityChiayi City 60004TaiwanChina Department of Food Science Rutgers UniversityNew BrunswickNJ 08901USA Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization Huanggang Normal UniversityHuanggang 438000China

Tea is the most popular functional beverage in the world and has been gaining more and more attention for its health beneficial *** common teas,black tea is consumed more than green tea and oolong tea *** studies have shown the biological activities of black tea and its polyphenols that include anti-oxidant,anti-tumor,anti-inflammation and metabolic *** polyphenols such as theaflavins and catechins are considered to be multifunctional compounds that could be effective in the prevention or treatment of various cancers,cardiovascular disease,chronic inflammation,obesity,metabolic syndrome,and neurodegenerative *** this review,we summarized the up-to-date research and underlying molecular mechanisms of black tea and its polyphenols.©2013 Beijing Academy of Food *** and hosting by Elsevier *** rights reserved.

关键词： Black tea Theaflavins Catechins Human disease Molecular mechanism Cancer