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Cardiology Discovery 2024年第1期4卷 5-14页

作者： chinese Society of Cardiology,chinese Medical Association Editorial Board of chinese Journal of Cardiology Muwei Li Yabin Wang Yaling Han Yun Zhang Feng Cao 不详 Fuwai Central China Cardiovascular Hospital chinese People’s Liberation Army General Hospital General Hospital of Northern Theater Command Qilu Hospital of Shandong University

Microcirculatory dysfunction(CMD)typically occurs in patients with acute ST-segment elevation myocardial infarction during percutaneous coronary intervention,which is associated with more severe myocardial injury and a worse *** the advancement of intracoronary physiology and imaging technology,the prevention and therapeutic interventions of CMD have attracted more ***,relevant guidelines or consensus on CMD are lacking in *** current consensus summarizes the prevention and diagnostic strategies of emergency percutaneous coronary intervention-related CMD and gives suggestions to improve the prognosis of ST-segment elevation myocardial infarction patients based on evidence from recent clinical studies,guidelines,and consensus from international sources.

关键词： Myocardial infarction Microcirculation dysfunction Percutaneous coronary intervention

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chinese Journal of Chemistry 2024年第16期42卷 1797-1805页

作者： Editorial Office of chinese Journal of Chemistry 不详

Editorial Board Memberof Rising Stars:Xiulin Fan,Professor,School of Materials science and Engineering Zhejiang University,Hangzhou,***:2003.2007,*** University,China.2007-2012,*** University,China(Supervisor:*** Chen).

关键词： China. Editorial Hangzhou

Evidence-based expert consensus on clinical management of safety of Bruton’s tyrosine kinase inhibitors(2024)

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chinese Journal of Cancer Research 2024年第3期36卷 240-256页

作者： Zaiwei Song Dan Jiang Lingling Yu Yixuan Chen Daobin Zhou Yue Li Depei Wu Lingli Zhang Liyan Miao Jun Ma Jun Zhu Hongmei Jing Rongsheng Zhao the Steering Committee,the Consensus Panel and the Evidence Synthesis Group Evidence-based Pharmacy Professional Committee of chinese Pharmaceutical Association(CPA) Hospital Pharmacy Professional Committee of chinese Pharmaceutical Association(CPA) Division of Therapeutic Drug Monitoring of chinese Pharmacological Society(CPS) Expert Committee on Lymphoma of chinese Society of Clinical Oncology(CSCO) Expert Committee on Leukemia of chinese Society of Clinical Oncology(CSCO) Society of Integrative Cardio-Oncology of China Anti-Cancer Association(CACA) chinese Society of Hematology of chinese Medical Association(CMA) Hospital Pharmacy Professional Committee of Cross-Straits Medicine Exchange Association(SMEA) Department of Pharmacy Peking University Third HospitalBeijing 100191China Institute for Drug Evaluation Peking University Health Science CenterBeijing 100191China Therapeutic Drug Monitoring and Clinical Toxicology Center Peking UniversityBeijing 100191China Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Hematology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China Department of Cardiology the First Affiliated HospitalHarbin Medical UniversityHarbin 150001China Department of Hematology the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Pharmacy Evidence-based Pharmacy CenterWest China Second HospitalSichuan UniversityChengdu 610041China Department of Pharmacy the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Hematology and Oncology Harbin Institute of Hematology and OncologyHarbin 150010China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of LymphomaPeking University Cancer Hospital&InstituteBeijing 100142China Department of Hematology Peking University Third HospitalBeijing 100191China 不详

Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell ***,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A comprehensive and systematic expert consensus from a pharmacological perspective is lacking for safety issues associated with BTKi treatment.A multidisciplinary consensus working group was established,comprising 3. members from the fields of hematology,cardiovascular disease,cardio-oncology,clinical pharmacy,and evidencebased *** evidence-based expert consensus was formulated using an evidence-based approach and the Delphi *** Joanna Briggs Institute Critical Appraisal(JBI)tool and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)approach were used to rate the quality of evidence and grade the strength of recommendations,*** consensus provides practical recommendations for BTKis medication based on nine aspects within three domains,including the management of common adverse drug events such as bleeding,cardiovascular events,and hematological toxicity,as well as the management of drug-drug interactions and guidance for special *** multidisciplinary expert consensus could contribute to promoting a multi-dimensional,comprehensive and standardized management of BTKis.

关键词： Consensus BTK inhibitors safety adverse drug events drug-drug interactions

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咖啡因的科学共识

中国食品学报 2024年第6期24卷 498-504页

作者：中国食品科学技术学会北京100048

咖啡因是一种常见于咖啡、茶叶和可可等植物中的天然活性成分,作为功能添加成分已在国际食品领域广泛应用多年,适量摄入有助于健康人群提高注意力,促进运动能力,缓解疲劳。国内外相关食品安全监管机构一致认为,咖啡因虽在日常饮食中的... 详细信息

咖啡因是一种常见于咖啡、茶叶和可可等植物中的天然活性成分,作为功能添加成分已在国际食品领域广泛应用多年,适量摄入有助于健康人群提高注意力,促进运动能力,缓解疲劳。国内外相关食品安全监管机构一致认为,咖啡因虽在日常饮食中的摄入是安全的,但需关注个体差异、摄入量以及频率。许多国家和地区已对咖啡因在食品中的应用制定了严格的应用限量和标识规定。为进一步提升大众对咖啡因的科学认知,消除对咖啡因的偏见,推动咖啡因在相关食品产业的合理应用,中国食品科学技术学会组织食品科学、公共卫生、食品安全与食品营养等领域专家与相关产业界代表,通过现场咨询、文献检索、专题研讨等形式和方法,经广泛讨论形成咖啡因的科学共识,以推动咖啡因在我国的规范使用。

关键词：咖啡因健康益处摄入量应用管理

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chinese Journal of Chemistry 2024年第16期42卷 1932-1936页

作者： Editorial Office of chinese Journal of Chemistry 不详

Editorial Board Member of *** ***,College of Materials science and Engineering Beijing University of Chemical ***:2006-2010,B.S.,Materials science and Engineering,Beijing University of Chemical Technology.2010-2015,Ph... 详细信息

关键词： Spotlight Editorial Board

^(40)Ar/^(3.)Ar dating of shear deformation of the Xianshuihe fault zone in west Sichuan and its tectonic significance

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science China Earth sciences 2004年第9期47卷 794-803页

作者： ZHANG Yueqiao1, CHEN Wen2, 3.& YANG Nong1 1. Institute of Geomechanics, chinese Academy of geological sciences, Beijing 100081, China 2. Institute of Geology, chinese Academy of geological sciences, Beijing 10003., China 3. Institute of Geology and Geophysics, chinese Academy of sciences, Beijing 100029, China Institute of Geomechanics Chinese Academy of Geological Sciences Beijing China Institute of Geology Chinese Academy of Geological Sciences Beijing China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing China

Based on field geological survey, structural measurements and classical Ar/Ar dating of mica, biotite and K-feldspar, we obtain cooling ages for Miocene left-lateral shear along the Xianshuihe fault zone. The results document two thermal events during the sinistral shear. The early event (12-10 Ma) corresponds to rapid cooling of the Zheduoshan granitic massif from above 700℃ to below 3.0℃. The late event (5-3.5 Ma) corresponds to cooling of granites intruded along the eastern side of the fault zone. These dating results provide important thermochronological constraint on the timing of late Cenozoic eastward extrusion of the Chuan-Dian Block in the SE Tibetan margin.

关键词： Xianshuihe fault zone, Zheduoshan granitic massif, sinistral shear deformation, 40Ar/3.Ar dating, late Cenozoic.

Animal models of hepatitis E infection: Advances and challenges

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 171-180页

作者： Ze Xiang Xiang-Lin He Chuan-Wu Zhu Jia-Jia Yang Lan Huang Chun Jiang Jian Wu chinese Consortium for the Study of Hepatitis E(CCSHE) Zhejiang University School of Medicine Hangzhou 310030China Department of Infectious Diseases The Fifth People’s Hospital of SuzhouSuzhou 215007China Department of Infection Management The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China Department of Clinical Laboratory The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China 不详

Hepatitis E virus(HEV)is one of the leading causes of acute viral hepatitis *** most of HEV infections are asymptomatic,some patients will develop the symptoms,especially pregnant women,the elderly,and patients with preexisting liver diseases,who often experience anorexia,nausea,vom-iting,malaise,abdominal pain,and *** infection may become chronic in immunosuppressed *** addition,HEV infection can also cause several extrahepatic *** exists in a wide range of hosts in nature and can be transmitted across ***,animals susceptible to HEV can be used as *** establishment of animal models is of great significance for studying HEV transmission,clinical symptoms,extrahepatic manifestations,and therapeutic strategies,which will help us understand the pathogenesis,prevention,and treatment of hepatitis *** review summarized the animal models of HEV,including pigs,monkeys,rabbits,mice,rats,and other *** each animal species,we provided a concise summary of the HEV genotypes that they can be infected with,the cross-species transmission pathways,as well as their role in studying extrahepatic manifestations,prevention,and treatment of HEV *** advantages and disadvantages of these animal models were also *** review offers new perspectives to enhance the current understanding of the research landscape surrounding HEV animal models.

关键词： Hepatitis E virus Animal models Pathogenesis Prevention Treatment

The effects of K^+ growth conditions on the accumulation of cesium by the bacterium Thermus sp. TibetanG6

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science China(Life sciences) 2006年第2期49卷 123-129页

作者： WANG Hailei1,2,3. KONG Fanjing1,2,3.& ZHENG Mianping1,2,3.1. R&D Center for Saline Lake and Epithermal Deposits, chinese Academy of geological sciences, Beijing 10003., China 2. Key Open Laboratory of Saline Lake Resources and Environment, chinese Academy of geological sciences, Beijing 10003., China 3. Institute of Mineral Resources, chinese Academy of geological sciences, Beijing 10003., China R&D Center for Saline Lake and Epithermal Deposits Chinese Academy of Geological Sciences Beijing China Key Open Laboratory of Saline Lake Resources and Environment Chinese Academy of Geological Sciences Beijing China Institute of Mineral Resources Chinese Academy of Geological Sciences Beijing China

The accumulation of cesium by the bacterium Thermus sp. TibetanG6 was examined under different K+ growth conditions. The effects of external pH and Na+ on the accumulation of ce-sium were also studied, and the mechanism involved was discussed. K+ regimes played an important role in the accumulation of cesium by the strain TibetanG6. The quantity of cesium accumulated (24 h) was much higher in K+-deficient regime than that in K+-sufficient regime. The pH and Na+ had different effects on the accumulation of cesium in the two K+ regimes. IR spectra analyses indicated that the biosorption is a process of homeostasis with cesium initially accumulated on the cell wall.

关键词： Thermus sp. TibetanG6, cesium, bioaccumulation, K+-growth condition, pH, sodium, IR spectroscopy.

Expert Consensus on the Prevention and Treatment of Chronic Hepatitis B in Children

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Infectious Diseases & Immunity 2024年第3期4卷 106-120页

作者： chinese Society of Infectious Diseases chinese Medical Association chinese Society of Hepatology chinese Medical Association Group of Infectious Diseases chinese Pediatric Society chinese Medical Association National Clinical Research Center for Infectious Diseases(Beijing) Fu-Sheng Wang Shishu Zhu Min Zhang Jianshe Wang Shuangjie Li Junliang Fu Yuanyuan Li Yuming Guo Jing Li Hongmei Xu Wenxian Ouyang Yuemin Nan Sainan Shu Shuangsuo Dang Xiaoyuan Xu Taisheng Li Jinlin Hou 不详 The Fifth Medical Center of PLA General Hospital Beijing 100039China Fudan University Children’s Hospital Hunan Children’s Hospital Children’s Hospital of Chongqing Medical University Third Hospital Hebei Medical University Tongji Hospital Tongji Medical CollegeHuazhong University of Science and Technology The Second Affiliated Hospital of Xi’an Jiaotong University Peking University First Hospital Peking Union Medical College Hospital Chinese Academy of Medical Sciences&Peking Union Medical College Nanfang Hospital Southern Medical University

The aim of this consensus is to standardize the prevention, diagnosis, and treatment of chronic hepatitis B in children and to achieve the goal of “eliminating viral hepatitis as a major public health threat by 203.” issued by the World Health Organization. Formulated by organized experts of the chinese Society of Infectious Diseases and chinese Society of Hepatology, chinese Medical Association;Group of Infectious Diseases, chinese Pediatric Society, chinese Medical Association;and the National Clinical Research Center for Infectious Diseases (Beijing), the consensus provides the latest evidence and recommendations for the prevention, diagnosis, and treatment of chronic hepatitis B in children.

关键词： Chronic hepatitis B Children Treatment Prevention Consensus

Integrated precise orbit determination of Shenzhou IV unmanned spacecraft

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science China(Technological sciences) 2004年第5期47卷 518-525页

作者： L Congmin1,2, GU Yidong3. LIN Baojun3.& GUO Jiong3.1. Center for Space science and Applied Research, chinese Academy of sciences, Beijing 100080, China 2. Graduate School of the chinese Academy of sciences, Beijing 10003., China 3. General Establishment of Space science and Application, chinese Academy of sciences, Beijing 100080, China Correspondence should be addressed to L Congmin General Establishment of Space science and Application Chinese Academy of Sciences

Considering the characteristic orbit of Shenzhou IV spacecraft and the advantages and disadvantages of several types of domestic orbit measurements, a scheme of IPOD is determined, which uses GPS, SLR and USB observation data jointly plus precise ionosphere corrections to GPS observation data. IPOD system and mathematic models of OD are introduced. The results of different joint OD are analyzed using true observation data, and show that radial accuracy is better than 2 m.

关键词： Shenzhou IV unmanned spacecraft integrated precise orbit determination GPS SLR USB.