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Influence mechanism of government subsidy on the green transformation of coal company in china

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International Journal of Mining Science and Technology 2024年第07期 1033-1040页

作者： Xiaolei li Changsong Wu school of Management China University of Mining and Technology-Beijing school of Economics and Management China University of Mining and Technology

The optimization of government subsidies to enhance the efficiency of coal companies' green transformation constitutes a critical component in the pursuit of global sustainability. We investigate the influence mechanism of government subsidies on the green transformation using data from the listed coal companies in china from 2007 to 2022. According to our findings and hypothesis testing, previous government subsidies did not have a significant direct impact on coal companies' green transformation. Nevertheless,government subsidies can help coal companies transition to greener practices by promoting innovative green initiatives. Furthermore, we confirmed an indirect route: that government subsidies enable the adoption of low-carbon initiatives, which in turn could facilitate the transition of coal companies towards green practices. In addition, we discovered that the coal company's digitization will improve this indirect route. Thus, we propose increasing the effectiveness of government subsidies in facilitating coal companies' transition to green practices by focusing on technological advancements and enhancing company digitalization.

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Chitosan-based thermosensitive hydrogel with long-term release of murine nerve growth factor for neurotrophic keratopathy

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Neural Regeneration Research 2024年第3期19卷 680-686页

作者： Jie Wu Yulei Huang Hanrui Yu Kaixiu li Shifeng Zhang Guoqing Qiao Xiao liu Hongmei Duan Yifei Huang Kwok-Fai So Zhaoyang Yang Xiaoguang li liqiang Wang Department of Ophthalmology the Third Medical CenterChinese PLA General HospitalBeijingChina The PLA Medical College Department of NephrologyChinese PLA Institute of NephrologyState Key Laboratory of Kidney DiseasesNational Clinical Research Center for Kidney DiseasesBeijingChina Department of Ophthalmology Hainan Hospital of Chinese PLA General HospitalSanyaHainan ProvinceChina Medical school of Chinese PLA BeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Guangdong-Hongkong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administrative RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-Hong Kong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina school of Engineering Medicine Beijing Key Laboratory for Biomaterials and Neural RegenerationBeihang UniversityBeijingChina Beijing International Cooperation Bases for Science and Technology on Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Big Data-Based Precision MedicineBeihang UniversityBeijingChina

Neurotrophic keratopathy is a persistent defect of the corneal epithelium,with or without stromal ulceration,due to corneal nerve deficiency caused by a variety of *** treatment options for neurotrophic keratopathy are *** this study,an ophthalmic solution was constructed from a chitosan-based thermosensitive hydrogel with long-term release of murine nerve growth factor(CTH-mNGF).Its effectiveness was evaluated in corneal denervation(CD)mice and patients with neurotrophic *** the preclinical setting,CTH-mNGF was assessed in a murine corneal denervation ***-mNGF was transparent,thermosensitive,and ensured sustained release of mNGF for over 20 hours on the ocular surface,maintaining the local mNGF concentration around 1300 pg/mL in *** denervation mice treated with CTH-mNGF for 10 days showed a significant increase in corneal nerve area and total corneal nerve length compared with non-treated and CTH treated mice.A subsequent clinical trial of CTH-mNGF was conducted in patients with stage 2 or 3 neurotrophic *** received topical CTH-mNGF twice daily for 8 *** sodium images,Schirmer’s test,intraocular pressure,Cochet-Bonnet corneal perception test,and best corrected visual acuity were *** total,six patients(total of seven eyes)diagnosed with neurotrophic keratopathy were *** 8 weeks of CTH-mNGF treatment,all participants showed a decreased area of corneal epithelial defect,as stained by ***,six out of seven eyes had fluorescence staining scores<***,best corrected visual acuity,intraocular pressure,Schirmer’s test and Cochet-Bonnet corneal perception test results showed no significant *** increase in corneal nerve density was observed by in vivo confocal microscopy after 8 weeks of CTH-mNGF treatment in three out of seven *** study demonstrates that CTH-mNGF is transparent,thermosensitive,and has sustained-release *** effecti

关键词： chitosan corneal reinnervation murine nerve growth factor neurotrophic keratopathy thermosensitive hydrogel

Estimates for stress concentration between two adjacent rigid inclusions in two-dimensional Stokes flow

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Science china Mathematics 2024年

作者： Haigang li Longjuan Xu school of Mathematical Sciences Beijing Normal University Academy for Multidisciplinary Studies Capital Normal University

It is vitally important in material sciences and fluid mechanics to study the field enhancements in the narrow region between two inclusions. Complex fluids including particle suspensions usually result in complicated flow behavior. In this paper, we establish the pointwise upper bounds of the gradient and the second-order partial derivatives for the Stokes flow when two rigid particles are closely spaced, suspending in an open bounded domain and away from the boundary in dimension two. Moreover, the lower bounds of the gradient estimates at the narrowest place of the neck region show the optimality of the blow-up rate. These results are valid for inclusions with arbitrary shapes.

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口服中成药联合常规西医治疗胃食管反流病的网状Meta分析

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中国中药杂志 2024年第17期49卷 4786-4800页

作者：主佳旭于滨洋李显高蕊中国中医科学院研究生院北京中医药大学研究生院中国中医科学院西苑医院

运用网状Meta分析对不同口服中成药联合常规西医治疗胃食管反流病(GERD)的疗效和安全性进行评价。检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane library、EMbase、Web of Scie... 详细信息

运用网状Meta分析对不同口服中成药联合常规西医治疗胃食管反流病(GERD)的疗效和安全性进行评价。检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane library、EMbase、Web of Science数据库，从建库至2023年9月收录的口服中成药联合常规西医治疗GERD的随机对照试验(RCT),运用Cochrane风险偏倚评估工具对纳入文献进行质量评价，采用RevMan 5.4、Strata 16软件进行数据分析。最终纳入47篇RCTs,包含健胃愈疡片、气滞胃痛颗粒、达立通颗粒、六味安消胶囊、康复新液、胃苏颗粒、枳术宽中胶囊、小柴胡颗粒、逍遥丸、胆胃康胶囊共10种口服中成药。网状Meta分析显示，(1)临床症状有效率方面，累计概率排名曲线下面积(surface under the cumulative ran-king curve, SUCRA)排序第1的干预措施为达立通颗粒+常规西医；(2)内镜下有效率方面，SUCRA排序第1的干预措施为六味安消胶囊+常规西医；(3)升高血清胃泌素水平方面，SUCRA排序第1的干预措施为胃苏颗粒+常规西医；(4)升高血浆胃动素水平方面，SUCRA排序第1的干预措施为逍遥丸+常规西医。在症状积分、生存质量、复发率方面，由于各研究间异质性较大，仅做描述性分析，但各研究均报道了中成药联合常规西医对结局指标的改善优于常规西医，差异均具有统计学意义。不良反应方面，中成药联合常规西医与单用常规西医相比差异无统计学意义。通过聚类分析可知，达立通颗粒+常规西医、胆胃康胶囊+常规西医、气滞胃痛颗粒+常规西医、康复新液+常规西医、六味安消胶囊+常规西医综合疗效较突出，可同时改善临床症状和内镜下炎症。结果表明，口服中成药联合常规西医治疗GERD能够提高综合疗效，改善临床症状，调节胃肠动力。但由于纳入文献样本量及质量等限制，结论有待更多大样本、高质量的研究加以验证。

关键词：中成药胃食管反流病(GERD) 网状Meta分析

A Study of Epileptogenic Foci Localization Algorithm Based on Automatic Detection of Comprehensive Feature HFOs and RF-LR

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Chinese Journal of Electronics 2024年

作者： Yuxiao DU Gaoming li school of Automation Guangdong University of Technology

Studies have shown that fast ripples of 250–500 Hz in epileptic electroencephalography(EEG) signals are more pathological and closer to the epileptogenic focus itself compared to ripples of 80–250 Hz. However, artifacts of fast ripples and high-frequency oscillations(HFOs) are easily confused and difficult to discriminate, and manual visual screening is both time-consuming and unable to avoid subjectivity. To this end, this paper presents a method for localizing epileptogenic foci based on the automatic detection of integrated feature HFOs and random forest-logistic regression(RF-LR). In this paper, we first extract multivariate features from the preprocessed epileptic EEG signals, and use the random forest algorithm to filter out three features with high importance, based on which,suspicious leads containing HFOs are identified. Then, wavelet time-frequency maps were used for the primary screening of suspected leads to improve the signal calibration efficiency and further localize HFOs in time and frequency. Finally, a logistic regression model was used to automatically classify and identify ripples and fast ripples in HFOs. The results show that the sensitivity, specificity, and accuracy of the model for detecting ripple are 89.37%, 88.26%, and 90.1%, respectively; the sensitivity, specificity, and accuracy for detecting fast ripple are 94.31%, 94.83%,and 93.46%, respectively. Compared with single features, the multivariate features in this paper more comprehensively characterize the complex epileptic EEG signals and provide more accurate information for the localization of epileptogenic foci. The automatic detection algorithm of HFOs proposed in this paper can analyze a large amount of data in a short time and has a good detection performance, which can help clinicians accurately determine the region of epileptogenic foci.

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Minimal Legendrian surfaces in the tangent sphere bundle of ■

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Science china Mathematics 2024年

作者： Mingyan li Guofang Wang school of Mathematical Sciences Ocean University of China Mathematisches Institut Albert-Ludwigs-Universit?t Freiburg

In this paper, we study minimal Legendrian surfaces Σ immersed in the tangent sphere bundle T1■3. We classify（1） totally geodesic Legendrian surfaces,（2） closed minimal Legendrian surfaces of genus smaller than or equal to 1 and complete minimal Legendrian surfaces with the non-negative Gauss curvature,and（3） complete stable minimal Legendrian surfaces.

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冲击式水轮机转轮水斗汛期泥沙磨损特性分析

水力发电学报 2024年第2期43卷 15-22页

作者：李彦浩朱逸林肖业祥刘洁梁权伟李海军上海勘测设计研究院有限公司上海200335 清华大学水圈科学与水利工程全国重点实验室北京100084 清华大学能源与动力工程系北京100084 中国三峡建工(集团)有限公司成都610014 东方电气集团东方电机有限公司四川德阳618000

泥沙磨损是冲击式水轮机水力部件失效的主要原因之一,特别是在汛期时,过机泥沙含量会大幅增加,而转轮水斗表面的挟沙三相流动过程复杂,其磨损问题会更为严重。本文以规划建设的西藏紫霞电站冲击式水轮机为研究对象,根据设计院提供的电... 详细信息

泥沙磨损是冲击式水轮机水力部件失效的主要原因之一,特别是在汛期时,过机泥沙含量会大幅增加,而转轮水斗表面的挟沙三相流动过程复杂,其磨损问题会更为严重。本文以规划建设的西藏紫霞电站冲击式水轮机为研究对象,根据设计院提供的电站实测泥沙特性数据,采用Mansouri磨损模型和欧拉-拉格朗日方法对泥沙颗粒在转轮水斗表面的流动过程进行了三相流动数值模拟,分析了电站在汛期高泥沙浓度下颗粒的流动特性以及水斗表面的磨损分布。预测的水斗表面磨损分布与文献中实测的较为一致,预测结果表明水斗主要磨损区分布在靠近水斗根部的出水边附近以及缺口边附近;磨损分布和冲击次数的分布相似度最高,冲击次数对泥沙磨损的影响很大。

关键词：冲击式水轮机含沙三相流磨损预测冲击特性数值计算

Tracking direct and indirect impact on technology and policy of transformative research via ego citation network

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Journal of Data and Information Science 2024年第3期9卷 65-87页

作者： Xian li Xiaojun Hu College of Computer and Information Science Southwest UniversityChongqing 400037China Medical Information Center Zhejiang University School of MedicineHangzhou 310058China

Purpose:The disseminating of academic knowledge to nonacademic audiences partly relies on the transition of subsequent citing *** study aims to investigate direct and indirect impact on technology and policy originating from transformative research based on ego citation ***/methodology/approach:Key Nobel Prize-winning publications(NPs)in fields of gene engineering and astrophysics are regarded as a proxy for transformative *** this contribution,we introduce a network-structural indicator of citing patents to measure technological impact of a target article and use policy citations as a preliminary tool for policy ***:The results show that the impact on technology and policy of NPs are higher than that of their subsequent citation generations in gene engineering but not in *** limitations:The selection of Nobel Prizes is not balanced and the database used in this study,Dimensions,suffers from incompleteness and inaccuracy of citation *** implications:Our findings provide useful clues to better understand the characteristics of transformative research in technological and policy ***/value:This study proposes a new framework to explore the direct and indirect impact on technology and policy originating from transformative research.

关键词： Transformative research Nobel Prize winning articles Citation networks Technological impact Policy impact

Design of zero-determinant strategies and its application to networked repeated games

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Science china(Information Sciences) 2024年第10期 227-243页

作者： Daizhan CHENG Changxi li Key Laboratory of Systems and Control Academy of Mathematics and Systems SciencesChinese Academy of Sciences school of Mathematics Shandong University

Using the semi-tensor product（STP） of matrices, the profile evolutionary equation（PEE） for repeated finite games is obtained. By PEE, the zero-determinant（ZD） strategies are developed for general finite games. A formula is then obtained to design ZD strategies for general finite games with multiple players and asymmetric strategies. A necessary and sufficient condition is obtained to ensure the availability of the designed ZD strategies. It follows that player i can unilaterally design ki-1（one less than the number of its strategies） dominating linear relations about the expected payoffs of all players. Finally, the fictitious opponent player is proposed for networked repeated games（NRGs）. A technique is proposed to simplify the model by reducing the number of frontier strategies.

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