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A PETROGRAPHICAL STUDY OF THE CHINESE AGALMATOLITES

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地质学报 1928年第Z1期 223-234页

作者： H.T.lee Geological Survey Peiping.

Ⅰ. INTRODUCTION. The most popular Chinese agalmatolites are Shoushanshih (壽山石), Changhuashih (昌化石), Chingtienshih (青田石) and Kwanglushih (廣綠石). They are named after the names of places, as the name Shousha... 详细信息

关键词： A PETROGRAPHICAL STUDY OF THE CHINESE AGALMATOLITES

Advanced 4D-bioprinting technologies for brain tissue modeling and study

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International Journal of Smart and Nano Materials 2019年第3期10卷 177-204页

作者： Timothy J.Esworthy Shida Miao Se-Jun lee Xuan Zhou Haitao Cui Yi Y.Zuo Lijie Grace Zhang Department of Mechanical and Aerospace Engineering The George Washington UniversityWashingtonDCUSA Department of Mechanical Engineering University of Hawaii at ManoaHonoluluHIUSA Department of Medicine The George Washington UniversityWashingtonDCUSA Department of Biomedical Engineering The George Washington UniversityWashingtonDCUSA Department of Electrical and Computer Engineering The George Washington UniversityWashingtonDCUSA

Although the process by which the cortical tissues of the brain fold has been the subject of considerable study and debate over the past few decades,a single mechanistic description of the phenomenon has yet to be fully ***,two competing explanations of cortical folding have arisen in recent years;known as the axonal tension and the differential tangential expansion *** the present review,these two models are introduced by analyzing the computational,theoretical,materials-based,and cell studies which have yielded *** Four-dimensional bioprinting is presented as a powerful technology which can not only be used to test both models of cortical folding de novo,but can also be used to explore the reciprocal effects that folding associated mechanical stresses may have on neural ***,the fabrication of‘smart’tissue models which can accurately simulate the in vivo folding process and recapitulate physiologically relevant stresses are *** also provide a general description of both cortical neurobiology as well as the cellular basis of cortical *** discussion also entails an overview of both 3D and 4D bioprinting technologies,as well as a brief commentary on recent advancements in printed central nervous system tissue engineering.

关键词： 4D bioprinting smart materials brain cortical folding gyrification

Managing Public Relationships via Corporate Blogs

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Journalism and Mass Communication 2015年第4期5卷 159-169页

作者： Kwanghee Kim Jaesub lee University of Houston Houston TX USA

This research explored the organization＇s public relationship management practices in corporate blogs on the web. Content analyses of corporate blogs of large Korean firms over two years in a longitudinal design revealed that relationship management strategies of openness, positivity and sharing of tasks were featured relatively strongly, whereas networking, access, and assurances were enacted relatively weakly. Further, most Korean corporate blogs utilized a tightly controlled top-down strategy. In addition, the use level of relationship management strategy was tied to the kind of corporate blogging strategies, but not to the industry type of the firms. Although utilized the same social media device, corporate blogs enacted different purposes and relational management activities in different countries, indicating that corporate blogs are largely cultural and driven locally.

关键词： public relationship management corporate blogs corporate blogging strategies Introduction

Umbili calcord blood R&D in Taiwan

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中国输血杂志 2001年第S1期14卷 297-298页

作者： Tsung Dao lee

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Long-primed germinal centres with enduring affinity maturation and clonal migration

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四川生理科学杂志 2022年第9期44卷 1618-1618页

作者： Jeong Hyun lee Center for Infectious Disease and Vaccine Research La Jolla Institute for Immunology La Jolla CA USA Consortium for HIV/AIDS Vaccine Development The Scripps Research Institute La Jolla CA USA IAVI Neutralizing Antibody Center The Scripps Research Institute La Jolla CA USA Department of Immunology and Microbiology The Scripps Research Institute La Jolla CA USA Department of Medicine Division of Infectious Diseases and Global Public Health University of California San Diego La Jolla CA USA Department of Integrative Structural and Computational Biology The Scripps Research Institute La Jolla CA USA Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Cambridge MA USA Tulane National Primate Research Center Tulane School of Medicine Covington LA USA Emory National Primate Research Center and Emory Vaccine Center Emory University School of Medicine Atlanta GA USA Department of Surgery Laboratory for AIDS Vaccine Research & Development Duke University Medical Center Duke University Durham NC USA Ragon Institute of Massachusetts General Hospital Massachusetts Institute of Technology and Harvard University Cambridge MA USA Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA USA Department of Materials Science and Engineering Massachusetts Institute of Technology Cambridge MA USA Howard Hughes Medical Institute Chevy Chase MD USA

Germinal centres are the engines of antibody evolution. Here, using human immunodeficiency virus (HIV) Env protein immunogen priming in rhesus monkeys followed by a long period without further immunization, we demonstrate germinal centre B (BGC) cells that last for at least 6 months. A 186-fold increase in BGC cells was present by week 10 compared with conventional immunization. Single-cell transcriptional profiling showed that both light- and dark-zone germinal centre states were sustained. Antibody somatic hypermutation of BGC cells continued to accumulate throughout the 29-week priming period, with evidence of selective pressure. Env-binding BGC cells were still 49-fold above baseline at 29 weeks, which suggests that they could remain active for even longer periods of time. High titres of HIV-neutralizing antibodies were generated after a single booster immunization. Fully glycosylated HIV trimer protein is a complex antigen, posing considerable immunodominance challenges for B cells1,2. Memory B cells generated under these long priming conditions had higher levels of antibody somatic hypermutation, and both memory B cells and antibodies were more likely to recognize non-immunodominant epitopes. Numerous BGC cell lineage phylogenies spanning more than the 6-month germinal centre period were identified, demonstrating continuous germinal centre activity and selection for at least 191 days with no further antigen exposure. A long-prime, slow-delivery (12 days) immunization approach holds promise for difficult vaccine targets and suggests that patience can have great value for tuning of germinal centres to maximize antibody responses.

关键词： sustained centre holds

A TDOA-Based Ultrasonic Absolute Localizing System of a Rail Robot in Greenhouse

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Journal of Measurement Science and Instrumentation 2011年第3期2卷 288-292页

作者： Jang-myung lee Dept.of Electronic Engineering Pusan National University

In this paper,we present a method for localization of a rail autonomous pesticide spraying and sampling robot working in greenhouse using an absolute localization *** and implementation of the localization system comes from the usage of beacon systems each of which is composed of an RF single receiver and an ultrasonic *** RF single receiver gets the synchronization signal from the mobile robot,and the ultrasonic transmitter sends ultrasonic signal,thus the distance from the beacon to the ultrasonic receiver can be *** position of a beacon in coordinate system of robot can be calculated according to distance information from the beacons to two ultrasonic receivers which are mounted on the *** on the coordinate transformation,the position of a mobile robot can be calculated from the beacon＇s absolute position information in the global coordinate *** demonstrate the effectiveness of the proposed method in real world applications.

关键词： TDOA rail robot absolute localization active beacon navigation

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Warming Relations

Beijing Review 2016年第15期59卷 24-25页

作者： Mara lee Durrell

When Syrian government troops re- took the ancient city of Palmyra on March 27 from the so-called ＂Islamic State＂ extremist group （ISIS）, much of the credit for weakening the terrorist group was given to an unlike... 详细信息

关键词： ISIS 伊斯兰叙利亚俄罗斯

Saline and Heparinised Flush in Maintaining Patency ofArterial Catheters in Adult PatientsmA SystematicReview

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Journal of Health Science 2014年第12期2卷 571-583页

作者： Jasmine lee Phillip Della National Heart Centre Singapore Singapore 169609 Curtin University GPO Box U1987 Perth 6845 Western Australia

This paper compares the effectiveness of normal saline and heparinised saline as a flushing solution in maintaining patencyof arterial catheters. Use of heparin as a flushing solution in maintaining patency of intra- arterial catheters has been a recognizedpractice. Due to its anticoagulation properties, heparin can cause side effects like heparin-induced thromhocytopenia in hypersensitivepatients. The alternative, normal saline solution increases the accuracy of patients＇ coagulation status and enhances safer clinicalpractice. A systematic search was conducted at Cochrane Library, Medline, CINAHL, OVID and Joanna Briggs Institute. Reviewperiod covered from 1990 to 2011. Methodological validity of included studies was evaluated using SIGN grading checklists fromScottish Intercollegiate Guidelines Network. There is inconsistent evidence and sample sizes were too small to allow statisticalsignificance to be achieved. Meta-analysis was performed for 2 studies; results revealed that heparinised saline offers no addedadvantage over normal saline. There is insufficient evidence to support the use of heparinised saline for flushing arterial catheters. Arigorous research design is needed to determine variables known to influence patency of arterial catheters. Sound clinical judgementmust be exercised in situations that require the need of heparinised saline.

关键词： Heparinised saline, normal saline, arterial catheters, patency, nursing.

Heterodimer formation between c-Jun and Jun B proteins mediated by Epstein Barr virus encoded latent membrane protein 1

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Science China(Life Sciences) 2005年第1期48卷 70-80页

作者： Leo M.lee Laboratory of Molecular Technology SAIC-Frederick

Epstein-Barr virus (EBV) encoded latent membrane protein 1 (LMP1) may trigger the transcription factor AP-1 including c-Jun and c-fos. In this report, using a Tet-on LMP1 HNE2 cell line which is a dual-stable LMP1 integrated nasopharyngeal carcinoma (NPC) cell line and the expression of LMP1 in which could be regulated by the Tet-on system, we show that Jun B can efficiently form a new heterodimeric complex with the c-Jun protein under the regulation of LMP1, phosphorylation of c-Jun (ser 63, ser 73) and Jun B is involved in the process of the new heterodimeric formation. We also find that this heterodimeric form can bind to the AP-1 consensus sequence. Transfection studies suggest that JNK interaction protein (JIP) could inhibit the heterodimer formation of c-Jun and Jun B through blocking the AP-1 signaling pathway triggered by LMP1. The interaction and function between c-Jun protein and Jun B protein increase the repertoire of possible regulatory complexes by LMP1 that could play an important role in the regulation of transcription of specific cellular genes in the process of genesis of nasopharyngeal carcinoma.

关键词： Epstein Barr virus, latent membrane protein 1, Jun B, c-Jun, heterodimer, DNA binding, JNK, JIP.

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