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Enhanced Electrochemical and Physical Properties of Ag/AgCl Planar Reference Electrodesin Potentiometric Sensors by Graphite Oxide Layer

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材料科学与工程（中英文A版） 2019年第2期9卷 83-90页

作者： Tung Son Vinh Nguyen Tien Minh Huynh Tin Chanh Duc Doan chien mau dang Community 6 Linh Trung Ward Thu Duc District Ho Chi Minh City 800010 Vietnam

The most common reference electrode (RE) which is used in electrochemical measurements is the Ag/AgCl electrode. In this study, we present a novel solid-state Ag/AgCl planar electrode that was coated with a thin layer of Graphite Oxide (GO) as a protective layer. The Ag/AgCl planar electrode was fabricated by using the photolithography and lift-off method combined with the Ag[NH3]2Cl complex. The GO was produced by Hummer’s method and was deposited on top of the Ag/AgCl layer by drop-casting method. The layers of the fabricated reference electrode were characterized by micro Raman spectroscopy, Scanning Electron Microscopy (SEM) and Energy-dispersive X-ray spectroscopy (EDX). The responding time of the planar electrode was short and the signal was more stable in comparison to the plainAg/AgCl electrode. The Open Circuit Potential (OCP) measurement with the fabricated electrode as the RE and the platinum electrode as the working electrode in electrolyte solutions which had various pH values was performed with a linear response in pH ranges from pH 5 to pH 8 and the linear correlation coefficient (R^2 = 0.9899). Moreover, the coating of the GO layers also enhanced the durability of the modified electrode. The results showed that the modified Ag/AgCl electrode with a thin layer GO as the protective layer could be used as plana REs for the potentiometric sensors.

关键词： Graphite oxide potentiometric sensor Ag/AgCl reference electrode

Two-Stage Production Planning Under Stochastic Demand:Case Study of Fertilizer Manufacturing

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Computers, Materials & Continua 2022年第1期70卷 1195-1207页

作者： Chia-Nan Wang Shao-Dong Syu chien-Chang Chou Viet Tinh Nguyen dang Van Thuy Cuc Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Sunline NP Telecommunications Co.Ltd Kaohsiung80778Taiwan Department of Shipping Technology National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh City70000Vietnam Faculty of Industrial Engineering and Management International UniversityHo Chi Minh City70000Vietnam

Agriculture is a key facilitator of economic prosperity and nourishes the huge global *** achieve sustainable agriculture,several factors should be considered,such as increasing nutrient and water efficiency and/or improving soil health and *** fertilizer is one of the fastest and easiest ways to improve the quality of nutrients inland and increase the effectiveness of crop *** supplies most of the necessary nutrients for plants,and it is estimated that at least 30%-50%of crop yields is attributable to commercial fertilizer nutrient *** is always a major concern in achieving sustainable and efficient *** reasonable and customized fertilizerswill require a significant increase in the number of formulae,involving increasing costs and the accurate forecasting of the right time to apply the suitable *** alternative solution is given by two-stage production planning under stochastic demand,which divides a planning schedule into two *** primary stage has non-existing demand information,the inputs of which are the proportion of raw materials needed for producing fertilizer products,the cost for purchasing materials,and the production *** total quantity of purchased material and produced products to be used in the blending process must be defined to meet as small as possible a paid *** the second stage,demand appears under multiple scenarios and their respective *** stage will provide a solution for each occurring scenario to achieve the best *** two-stage approach is presented in this paper,the mathematical model of which is based on linear integer *** the diversity of fertilizer types,themathematicalmodel can advise manufacturers about which products will generate as much as profit as ***,two objectives are taken into ***,the paper’s thesis focuses on minimizing overall system costs,e.g.,including inventory cost,pur

关键词： Two-stage stochastic programming demand uncertainty planning blending fertilizer

Formulation Optimization Utilizing D-Optimal Experimental Design of Oral Capsules Containing Enteric-Coated Pellets of Lansoprazole and<i>in vivo </i>Bioequivalence

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Pharmacology & Pharmacy 2017年第5期8卷 153-171页

作者： Anh Quang Luong Thang Ngoc Vu dang Hoa Nguyen Sultan M. Alshahrani John Mark Christensen chien Ngoc Nguyen Department of Pharmacy National Institute of Burns Hanoi Vietnam Research and Training Center for Pharmacy Military Medical University Hanoi Vietnam Military Institute of Pharmaceutical Analysis and Research Hanoi Vietnam Department of Pharmaceutics Hanoi University of Pharmacy Hanoi Vietnam Department of Pharmaceutical Sciences College of Pharmacy Oregon State University Corvallis Oregon USA National Institute of Pharmaceutical Technology Hanoi University of Pharmacy Hanoi Vietnam

An optimized formulation of capsules containing Lansoprazole enteric-coated pellets using D-Optimal design with a polynomial statistical model were prepared by using Eudragit?L100 as an enteric coated polymer to provide resistance to simulated gastric acid dissolution in buffer media. D-Optimal experimental design was used to determine the optimal level for three coating layers that were applied to formulate the enteric-coated pellets including a drug loading layer, a sub-coating, and an outer enteric coating. Dissolution studies were performed on the prepared Lansoprazole capsules. Less than 5 percent of Lansoprazole was released in 60 minutes in an acidic dissolution medium (pH 1.2) and greater than 90 percent of active ingredient was released in the next 60 minutes in a buffer dissolution medium (pH 6.8). The Lansoprazole capsules were stable with no observable change in physico-chemical properties in accelerated and normal storage conditions for 6 and 18 months, respectively. The pharmacokinetic parameters Cmax, Tmax, AUC0-t, and AUC0-∞ were determined after administration of the D-Optimal design optimized capsules of LPZ to healthy beagle dogs and were statistically compared to Gastevin? capsules as a reference (KRKA, Slovenia) using the non-compartmental method with the aid of WinNonlin 5.2 software. The analysis of variance showed that the two formulations did not demonstrate bioequivalence using a 90% confidence interval range (80% - 120%) of Cmax, AUC0-t, and AUC0-∞. No significant difference in Tmax was found at the 0.95 significance level using the Wilcoxon signed-rank test. D-Optimal Experimental Design provided definitive direction for an optimal formulation of capsules containing enteric-coated pellets of lansoprazole loaded within the coating of pellets that provided similar bioequivalence to Gastevin.

关键词： Lansoprazole D-Optimal Pellets Enteric-Coating Pharmacokinetic Parameters

Biological Community in Submerged Caves and Marine Lakes in ha Long-Cat Ba Area, Vietnam

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Journal of Life Sciences 2015年第11期9卷 541-548页

作者： Nguyen dang Ngai Dau Van Thao Do Cong Thung Le Thi Thuy Dam Duc Tien Nguyen Van Quan PhamVan chien Institute of Marine Environment and Resources Vietnam Academic of Science and Technology Hai Phong City Vietnam

Submerged caves and marine lakes are two iconic and common ecosystems in Ha Long-Cat Ba area. However, their biological characteristics are poorly known since very limited studies have been conducted, The aim of this study was to investigate biodiversity in these ecosystems. Three submerged caves （Hang Sang, Hang Toi and Qua Bang） and three marine lakes （Dau Be, Ang Du and Qua Bang） were chosen for study. The results showed that organism communities in submerged caves were abundant with over 142 species found. The popular groups comprised sponge and soft coral which were distributed along the length of the caves. Several species with high economic value were widespread in the caves, including stone crab Myomenippe hardwickii, flower crab Portunus pelagicus, cone snails Trochus pyramis, shoemaker spinefoot Siganus sutor, snapper Lutjanus russellii. Species that permanently live in caves were not detected. In the lakes where water is well exchanged to the sea, coral reefs were found and they usually formed a narrow band around the lakes. Sandy beaches were often observed around the lakes at the depths of 0.5-2 m, containing specialty species as clam （Sanguinolaria diphos）, snout otter clam （Lutraria rhychaena）, sea cucumbers with high density （in Dau Be, Qua Bang）. There was no coral reef in the enclosed lake （Ang Du） because of low salinity.

关键词： Karst habitat biodiversity organism environment.

睡前服用缬沙坦氢氯噻嗪对非杓型高血压患者动态动脉硬化指数及尿微量白蛋白的影响

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中国临床研究 2019年第4期32卷 482-485页

作者：张倩辉张志梅王立立党懿李树仁河北省人民医院心脏中心河北石家庄050000 河北省人民医院内分泌科河北石家庄050000

目的探讨不同时间应用缬沙坦氢氯噻嗪片对非杓型高血压患者动态动脉硬化指数(AASI)及尿微量白蛋白(mau)的影响。方法纳入2015年6月至2017年3月就诊于河北省人民医院新诊断的80例1～2级非杓型高血压患者,采用随机化编码表法分为晨起服药... 详细信息

目的探讨不同时间应用缬沙坦氢氯噻嗪片对非杓型高血压患者动态动脉硬化指数(AASI)及尿微量白蛋白(mau)的影响。方法纳入2015年6月至2017年3月就诊于河北省人民医院新诊断的80例1～2级非杓型高血压患者,采用随机化编码表法分为晨起服药组和睡前服药组各40例,分别在晨起或睡前服用缬沙坦氢氯噻嗪片(每片含缬沙坦80 mg及氢氯噻嗪12.5 mg),所有患者治疗前及治疗12周后进行动态血压监测并记录AASI值,检测mau。AASI定义为1减去24 h舒张压(24 hMDBP)和收缩压(24 hMSBP)的回归系数。mau定义为男性尿白蛋白/肌酐比≥22 mg/g,或者女性尿白蛋白/肌酐比≥31 mg/g。结果晨起服药组和睡前服药组患者治疗后24 hMSBP、24 hMDBP较治疗前均显著降低(P均mau较治疗前降低(P均0.05),治疗后睡前服药组AASI、mau较晨起服药组降低(P均mau水平;不同时间服用缬沙坦氢氯噻嗪对24 hMSBP、24 hMDBP无影响,但睡前服药较晨起服药改善非杓型高血压患者的AASI、mau水平更显著。

关键词：血压节律动态动脉硬化指数尿微量白蛋白缬沙坦氢氯噻嗪

樟子松固沙林林水关系研究进展及对营林实践的指导

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植物生态学报 2022年第9期46卷 971-983页

作者：党宏忠张学利韩辉石长春葛玉祥马全林陈帅刘春颖中国林业科学研究院生态保护与修复研究所中国林业科学研究院荒漠化研究所北京100091 辽宁省沙地治理与利用研究所辽宁章古台科尔沁沙地生态系统国家定位观测研究站辽宁阜新123000 陕西省治沙研究所陕西榆林毛乌素沙地荒漠生态系统国家定位观测研究站陕西榆林719000 内蒙古红花尔基樟子松林国家级自然保护区管理局内蒙古呼伦贝尔021112 甘肃省治沙研究所甘肃省荒漠化与风沙灾害防治国家重点实验室培育基地兰州730070

中国有着世界上最大面积的人工林,如何维持人工林的可持续性已成为气候变化背景下需要面对的重大挑战。樟子松(Pinus sylvestris ***)以其抗旱、抗寒、耐贫瘠等优良特性成为中国北方生态治理中最主要的常绿针叶树种之一,近70年来发挥了... 详细信息

中国有着世界上最大面积的人工林,如何维持人工林的可持续性已成为气候变化背景下需要面对的重大挑战。樟子松(Pinus sylvestris ***)以其抗旱、抗寒、耐贫瘠等优良特性成为中国北方生态治理中最主要的常绿针叶树种之一,近70年来发挥了巨大的防风固沙与生态固碳功能。然而,随着林分的生长与气候变化,樟子松人工固沙林正经历着越来越严峻的环境胁迫,部分地区出现了林分“早衰”或死亡的现象,引起了人们对樟子松固沙林适应与应对气候变化能力的担忧。该文在回溯樟子松基本生物学特征与引种推广历史,系统总结近年来樟子松林林水关系研究新成果的基础上,全面分析了樟子松固沙林林水关系存在的主要矛盾,并提出了基于林水关系相协调的林分经营措施的调整:由倡导防护功能为主的单一目标向包含林分稳定性、生态固碳功能、可持续发展等多目标平衡方向调整;由以沙地森林景观培育为主向以良好土壤生境培育为主的方向调整;由倡导天然更新为主向以人工造林与天然更新相结合的世代更新方向调整。在立足于北方沙地脆弱生境与气候变化客观现实的基础背景下,应坚持樟子松在固沙林生态系统演化过程中的先锋种与建群种地位,基于“以水定绿”原则,采取“隔行带伐+再造林”等方式开展林分密度动态调控,促进林分向异龄林结构演化,促进樟子松固沙林生态服务的优质化和生态固碳功能的最大化。

关键词：樟子松防风固沙气候变化碳中和森林经营管理人工林

Situational Analysis Climate Change Impacts on the Livelihood and Adaptive Solutions of the Coastal Communities:A Case of Phu Tan District,Ca mau Province

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Journal of Environmental Science and Engineering(B) 2021年第6期10卷 237-250页

作者： Pham Chi Trung Duong Quoc Huy Doan Van Hue Nguyen Văn chien Center for Training and International Cooperation Vietnam Academy for Water ResourcesHa Noi City 11555Viet Nam South Institute for Water Resources Researches HCM City 750100Viet Nam

The Mekong River Delta has 7 coastal provinces including Tien Giang,Ben Tre,Tra Vinh,Soc Trang,Bac Lieu,Ca mau and Kien ***,Ca mau province which exposes to both the East and West sea with a coastline of 254 m(6 coastal districts:Dam Doi,Nam Can,Ngoc Hien,Phu Tan,Tran Van Thoi,U Minh)in the recent years,has been severely influenced by climate *** Ca mau province has lost nearly 10,000 ha of land and coastal forests;infrastructure and properties of local people along rivers have been eroded and seriously damaged;production activities are vulnerable to sea level rise and other hydro-meteorological *** life of coastal people mainly depends on agricultural *** main income is agricultural production,forestry,aquaculture and *** paper aims to provide a situational analysis on how climate change and natural disasters affect the livelihoods of coastal communities in Ca mau Province.A case study is conducted for Phu Tan District that addresses problems and proposes urgent measures for climate change adaptation in the near-and long-term planning.

关键词： Climate change livelihood coastal communities Ca mau province