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The efficacy of *** adjuvant chemotherapy on biliary tract cancer after R0 resection

chinese Journal of Cancer 2017年第5期36卷 222-230页

作者： young Saing Kim chi-young jeong Haa-Na Song Tae Hyo Kim Hong Jun Kim young-Joon Lee Soon Chan Hong Division of Hematology and Oncology Department of Internal MedicineGachon University Gil Medical Center Incheon 405.706 South Korea Department of Surgery Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine 79 Gangnam-roJinju 660.702 South Korea Department of Internal Medicine Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine Jinju 660.702 South Korea.

Background: The optimal treatment strategy for biliary tract cancer(BTC) after curative?intent resection remains con?troversial. The purpose of this study was to evaluate the efficacy of fluoropyrimidine?based adjuvant chemotherapy for BTC patients undergoing microscopically margin?negative(R0) ***: We retrospectively analyzed the clinical data of BTC patients who underwent curative?intent R0 resection. Patients were eligible if they received either fluoropyrimidine?based adjuvant chemotherapy or observation after R0 ***: A total of 153 patients were included. In the entire patient cohort, no significant differences were observed in 5?year overall survival(OS) rates(48.4% vs. 39.6%, P = 0.439) or 3?year recurrence?free survival(RFS) rates(49.1% vs. 39.5%, P = 0.299) between patients who received fluoropyrimidine?based adjuvant chemotherapy or observation. However, for patients with stages Ⅱ and Ⅲ BTC, chemotherapy significantly improved 5?year OS rate(52.4% vs. 35.6%, P = 0.002) and 3?year RFS rate(55.5% vs. 39.1%, P = 0.021) compared with ***: Fluoropyrimidine?based adjuvant chemotherapy may prolong the survival of patients with stages Ⅱ and Ⅲ BTC after R0 resection.

关键词： Biliary tract cancer Adjuvant chemotherapy Fluoropyrimidine R0 resection Prognosis

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Traumatic neuroma of remnant cystic duct mimicking duodenal subepithelial tumor:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3821-3827页

作者： Dong-Hwan Kim Ji-Ho Park Jin-Kyu Cho Jung-Wook Yang Tae-Han Kim Sang-Ho jeong young-Hye Kim young-Joon Lee Soon-Chan Hong Eun-Jung Jung young-Tae Ju chi-young jeong Ju-Yeon Kim Department of Surgery Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Pathology Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea

BACKGROUND Gastrointestinal subepithelial tumors(GSTs),incidentally detected during upper gastrointestinal(GI)endoscopy,may be lesions derived from the GI wall or may be caused by compression from external *** general,traumatic neuroma is a benign nerve tumor that results from postoperative nerve injury,occurring in the bile duct as one of the complications after *** is the first case report demonstrating that neuroma of the cystic duct can be incorrectly perceived as a duodenal subepithelial tumor by compressing the duodenal *** SUMMARY We report the case of a 72-year-old man with traumatic neuroma of the cystic duct after *** tumor was mistaken for a duodenal subepithelial tumor on preoperative upper GI endoscopy and endoscopic ultrasonography due to external compression of the GI *** patient had no symptoms,and his laboratory test results were ***,in a series of follow-up endoscopies,the tumor was found to have grown in size,so it was surgically *** lesion was completely removed by laparoscopic endoscopic cooperative *** patient was discharged on postoperative day 7 without *** Traumatic neuroma of the cystic duct can be mistaken for GSTs in GI endoscopy.

关键词： Case report Neuroma Tumor Endoscopy Laparoscopy Cholecystectomy

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Direct 4D printing of functionally graded hydrogel networks for biodegradable,untethered,and multimorphic soft robots

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International Journal of Extreme Manufacturing 2024年第2期6卷 407-416页

作者： Soo young Cho Dong Hae Ho Sae Byeok Jo jeong Ho Cho Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Mechanical Engineering Virginia TechBlacksburgVA 24061United States of America School of Chemical Engineering Sungkyunkwan UniversitySuwon 16419Republic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon 16419Republic of Korea

Recent advances in functionally graded additive manufacturing(FGAM)technology have enabled the seamless hybridization of multiple functionalities in a single *** robotics can become one of the largest beneficiaries of these advances,through the design of a facile four-dimensional(4D)FGAM process that can grant an intelligent stimuli-responsive mechanical functionality to the printed ***,we present a simple binder jetting approach for the 4D printing of functionally graded porous multi-materials(FGMM)by introducing rationally designed graded multiphase feeder *** graded cross-linking agents gradually form stable porous network structures within aqueous polymer particles,enabling programmable hygroscopic deformation without complex mechanical ***,a systematic bed design incorporating additional functional agents enables a multi-stimuli-responsive and untethered soft robot with stark stimulus *** biodegradability of the proposed 4D-printed soft robot further ensures the sustainability of our approach,with immediate degradation rates of 96.6%within 72 *** proposed 4D printing concept for FGMMs can create new opportunities for intelligent and sustainable additive manufacturing in soft robotics.

关键词： intelligent and sustainable additive manufacturing multi-material four-dimensional printing untethered soft robot multi-stimuli-responsive soft robot biodegradable soft robotics

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Combined Insights from Leachate Structure and Microstructure Characteristics for Eating Quality of Convenience Rice Processed by Super-Heated and Pressurized Steam Technologies

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Rice science 2024年第4期31卷 475-488,I0035,I0036页

作者： Mingyo HA Hyo-young jeong Ju Hun LEE Hyun-Jung CHUNG Division of Food and Nutrition Chonnam National UniversityGwangju 61186South Korea Department of Biotechnology College of Life Sciences and BiotechnologyKorea UniversitySeoul 02841South Korea Division of Food Science&Culinary Arts Shinhan UniversityGyeonggi 11644South Korea

Convenience rice has become widely popular due to its easy availability for cooking. This study investigated the starch structure and composition of leachate and the microstructure of reheated convenience rice using novel processing technologies: super-heated steaming(SHS), auto-electric cooking(AEC), and pressurized-steam cooking(PSC). Additionally, the effect of two different target water contents(58% and 63%) was also evaluated. The PSC_63% sample had the highest total solids and amylopectin amount in the leachate. The amylopectin amount in the leachate differed significantly based on the targeted water content. Morphological characterization revealed that the swelling of starch and the coated layer on the surface of rice grains were most pronounced in the PSC_63% sample due to the pressure processing. The textural hardness of the AEC_58% sample was much higher than that of the other samples. The PSC_63% sample had the highest textural adhesiveness value, which can be attributed to the highest amylopectin amount in the leachate. Sensory characterization showed that the PSC_63% sample had the highest glossiness, whiteness, moistness, and overall acceptability. The principal component analysis score plots presented substantial differences in the leachate and textural and sensory characteristics of reheated convenience rice among the different processing technologies.

关键词： reheated convenience rice starch structure leachate multi-scale structure eating quality processing technology

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Novel fabrication techniques for ultra-thin silicon based flexible electronics

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International Journal of Extreme Manufacturing 2024年第4期6卷 116-149页

作者： Ju young Lee jeong Eun Ju Chanwoo Lee Sang Min Won Ki Jun Yu School of Electrical and Electronic Engineering Yonsei University50 Yonsei-roSeodaemunguSeoul 03722Republic of Korea Department of Electrical and Computer Engineering Sungkyunkwan UniversitySuwon 16419Republic of Korea YU-Korea Institute of Science and Technology(KIST)Institute Yonsei University50Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Flexible electronics offer a multitude of advantages,such as flexibility,lightweight property,portability,and high *** unique properties allow for seamless applications to curved and soft surfaces,leading to extensive utilization across a wide range of fields in consumer *** applications,for example,span integrated circuits,solar cells,batteries,wearable devices,bio-implants,soft robotics,and biomimetic ***,flexible electronic devices have been developed using a variety of materials such as organic,carbon-based,and inorganic semiconducting ***(Si)owing to its mature fabrication process,excellent electrical,optical,thermal properties,and cost efficiency,remains a compelling material choice for flexible ***,the research on ultra-thin Si in the context of flexible electronics is studied rigorously *** thinning of Si is crucially important for flexible electronics as it reduces its bending stiffness and the resultant bending strain,thereby enhancing flexibility while preserving its exceptional *** review provides a comprehensive overview of the recent efforts in the fabrication techniques for forming ultra-thin Si using top-down and bottom-up approaches and explores their utilization in flexible electronics and their applications.

关键词： flexible electronics silicon fabrication technique top-down approach bottom-up approach

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氟嘧啶为基础的辅助化疗对胆道癌R0切除术后疗效的观察

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癌症 2018年第2期37卷 56-64页

作者： young Saing Kim chi-young jeong Haa-Na Song Tae Hyo Kim Hong Jun Kim young-Joon Lee Soon Chan Hong Division of Hematology and Oncology Department of Internal MedicineGachon University Gil Medical Center Department of Surgery Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine Department of Internal Medicine Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine

背景与目的胆道癌(biliary tract cancer,BTC)根治性切除术后的最佳治疗方案仍存有争议。本研究旨在评价以氟嘧啶为基础的辅助化疗对显微镜下切缘阴性(R0)切除BTC患者的疗效。方法回顾分析行根治性R0切除的BTC患者的临床资料。将R0切除... 详细信息

背景与目的胆道癌(biliary tract cancer,BTC)根治性切除术后的最佳治疗方案仍存有争议。本研究旨在评价以氟嘧啶为基础的辅助化疗对显微镜下切缘阴性(R0)切除BTC患者的疗效。方法回顾分析行根治性R0切除的BTC患者的临床资料。将R0切除术后接受以氟嘧啶为基础的辅助化疗或单纯R0切除的患者纳入本研究。结果本研究共纳入153例患者。对于全体患者,接受以氟嘧啶为基础的辅助化疗组患者与对照组患者的5年总生存(overall survival,OS)率(48.4%vs. 39.6%,P=0.439)和3年无复发生存(recurrence-free survival,RFS)率(49.1%vs. 39.5%,P=0.299)无显著差异。而对于Ⅱ、Ⅲ期BTC患者,化疗组比对照组的5年OS率(52.4%vs.35.6%,P=0.002)和3年RFS率(55.5%vs. 39.1%,P=0.021)有显著提高。结论以氟嘧啶为基础的辅助化疗可延长Ⅱ、Ⅲ期BTC患者R0切除术后的生存。

关键词：胆道癌辅助化疗氟嘧啶 R0切除术预后

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Significantly Improved High-Temperature Energy Storage Performance of BOPP Films by Coating Nanoscale Inorganic Layer

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Energy & Environmental Materials 2024年第2期7卷 30-38页

作者： Tiandong Zhang Hainan Yu young Hoon Jung Changhai Zhang Yu Feng Qingguo Chen Keon Jae Lee Qingguo chi School of Electrical and Electronic Engineering Harbin University of Science and TechnologyHarbin 150080China Department of Materials Science and Engineering Korea Advanced Institute of Science and TechnologyDaejeon 350701Korea

Biaxially oriented polypropylene(BOPP)is one of the most commonly used commercial capacitor films,but its upper operating temperature is below 105℃due to the sharply increased electrical conduction loss at high *** this study,growing an inorganic nanoscale coating layer onto the BOPP film's surface is proposed to suppress electrical conduction loss at high temperature,as well as increase its upper operating *** kinds of inorganic coating layers that have different energy band structure and dielectric property are grown onto the both surface of BOPP films,*** effect of inorganic coating layer on the high-temperature energy storage performance has been systematically *** favorable coating layer materials and appropriate thickness enable the BOPP films to have a significant improvement in high-temperature energy storage ***,when the aluminum nitride(AIN)acts as a coating layer,the AIN-BOPP-AIN sandwich-structured films possess a discharged energy density of 1.5 J cm^(-3)with an efficiency of 90%at 125℃,accompanying an outstandingly cyclic *** the discharged energy density and operation temperature are significantly enhanced,indicating that this efficient and facile method provides an important reference to improve the high-temperature energy storage performance of polymer-based dielectric films.

关键词： coating layer energy storage interfacial barrier polymer films

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Electrochemically Deposited CZTSSe Thin Films for Monolithic Perovskite Tandem Solar Cells with Efficiencies Over 17%

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Energy & Environmental Materials 2024年第1期7卷 147-152页

作者： Sun Kyung Hwang Ik Jae Park Se Won Seo Jae Hyun Park So jeong Park Jin young Kim Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Korea Department of Applied Physics Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials and Systems Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials(RIAM) Seoul National UniversitySeoul 08826Korea

In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2ZnSn(S,Se)4(CZTSSe),they have rarely been demonstrated due to the difficulty in implementing solution-processed perovskite top cell on the rough surface of the bottom ***,we firstly demonstrate an efficient monolithic two-terminal perovskite/CZTSSe tandem solar cell by significantly reducing the surface roughness of the electrochemically deposited CZTSSe bottom *** surface roughness(R_(rms))of the CZTSSe thin film could be reduced from 424 to 86 nm by using the potentiostatic mode rather than using the conventional galvanostatic mode,which can be further reduced to 22 nm after the subsequent ion-milling *** perovskite top cell with a bandgap of 1.65 eV could be prepared using a solution process on the flattened CZTSSe bottom cell,resulting in the efficient perovskite/CZTSSe tandem solar *** the current matching between two subcells involving the thickness control of the perovskite layer,the best performing tandem device exhibited a high conversion efficiency of 17.5%without the hysteresis effect.

关键词： CZTSSe monolithic tandem solar cells perovskite solution process surface roughness control

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Disordered Structure and Reversible Phase Transformation from K-Birnessite to Zn-Buserite Enable High-Performance Aqueous Zinc-lon Batteries

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Energy & Environmental Materials 2024年第3期7卷 100-111页

作者： Nibagani Naresh Suyoon Eom Sang Jun Lee Su Hwan jeong Ji-Won Jung young Hwa Jung Joo-Hyung Kim Department of Materials Engineering and Convergence Technology Gyeongsang National University(GNU)Jinju 52828South Korea School of Material Science and Engineering(Ceramic Engineering) Gyeongsang National University(GNU)Jinju 52828South Korea School of Materials Science and Engineering University of Ulsan(UOU)Ulsan 44776South Korea PLS-ⅡBeamline Division Pohang Accelerator Laboratory(PAL)Pohang 37673South Korea

The layeredδ-MnO_(2)(dMO)is an excellent cathode material for rechargeable aqueous zinc-ion batteries owing to its large interlayer distance(~0.7 nm),high capacity,and low cost;however,such cathodes suffer from structural degradation during the long-term cycling process,leading to capacity *** this study,a Co-doped dMO composite with reduced graphene oxide(GC-dMO)is developed using a simple cost-effective hydrothermal *** degree of disorderness increases owing to the hetero-atom doping and graphene oxide *** is demonstrated that layered dMO and GC-dMO undergo a structural transition from K-birnessite to the Zn-buserite phase upon the first discharge,which enhances the intercalation of Zn^(2+)ions,H_(2)O molecules in the layered *** GC-dMO cathode exhibits an excellent capacity of 302 mAh g^(-1)at a current density of 100 mAg^(-1)after 100 cycles as compared with the dMO cathode(159 mAhg^(-1)).The excellent electrochemical performance of the GC-dMO cathode owing to Co-doping and graphene oxide sheets enhances the interlayer gap and disorderness,and maintains structural stability,which facilitates the easy reverse intercalation and de-intercalation of Zn^(2+)ions and H_(2)O ***,GC-dMO is a promising cathode material for large-scale aqueous ZIBs.

关键词： aqueous zinc-ion batteries birnessite buserite disordered structure phase transformation

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Flexible mica films coated by magnetron sputtered insulating layers for high-temperature capacitive energy storage

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SusMat 2024年第5期4卷 154-162页

作者： Chao Yin Tiandong Zhang Changhai Zhang Yue Zhang Chang Kyu jeong Geon-Tae Hwang Qingguo chi Key Laboratory of Engineering Dielectrics and its Application Ministry of EducationHarbin University of Science and TechnologyHarbinChina School of Electrical and Electronic Engineering Harbin University of Science and TechnologyHarbinChina Division of Advanced Materials Engineering Jeonbuk National UniversityJeonjuSouth Korea Department of Materials Science and Engineering Pukyong National UniversityBusanSouth Korea

High-temperature energy storage performance of dielectric capacitors is cru-cial for the next generation of power electronic ***,conduction losses rise sharply at elevated temperature,limiting the application of energy storage ***,the mica films magnetron sputtered by different insulating layers are specifically investigated,which exhibit the excellent high-temperature energy storage *** experimental results revealed that the PbZrO3/Al2O3/PbZrO3(PZO/AO/PZO)interface insulating layers can effec-tively reduce the high-temperature leakage current and conduction loss of the composite ***,the ultrahigh energy storage density(Wrec)and charge‒discharge efficiency(η)can be achieved simultaneously in the flexi-ble mica-based composite ***,PZO/AO/PZO/mica/PZO/AO/PZO(PAPMPAP)films possess excellent Wrec of 27.5 J/cm3 andηof 87.8%at 200◦C,which are significantly better than currently reported high-temperature capaci-tive energy storage dielectric *** with outstanding power density and electrical cycling stability,the flexible films in this work have great appli-cation potential in high-temperature energy storage ***,the magnetron sputtering technology can deposit large-area nanoscale insulating layers on the surface of capacitor films,which can provide technical support for the industrial production of capacitors.

关键词： energy storage high temperature insulating layer magnetron sputtering mica

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