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Nuclear Science and Techniques 2020年第12期31卷 20-31页

作者： chi-che hung Fraser King Yun-chen Yu chi-Jen chen Yuan-chieh Wu Wei-Ting Lin 机构不详

This paper presents a corrosion assessment of copper spent nuclear fuel disposal canisters in crystalline rock,using hydrogeological modeling.A simplified approach is considered,to avoid complex and time-consuming computer *** simplified case is presented as a base case,with changes in the hydrogeological parameters presented as variant *** results show that in Taiwan’s base case,decreasing the hydraulic conductivity of the rock or decreasing the hydraulic conductivity of dikes results in a shorter transport path for sulfide and an increase in corrosion ***,the estimated canister failure time is still over one million years in the variant cases.

关键词： Spent nuclear fuel disposal Corrosion assessment Hydrogeological modeling

Role of metabolic dysfunction and inflammation along the liver-brain axis in animal models with obesity-induced neurodegeneration

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Neural Regeneration Research 2025年第4期20卷 1069-1076页

作者： Evridiki Asimakidou Eka Norfaishanty Saipuljumri chih hung Lo Jialiu Zeng Department of Clinical Neurosciences University of CambridgeCambridgeUK School of Applied Science Republic PolytechnicSingaporeSingapore Lee Kong chian School of Medicine Nanyang Technological UniversitySingaporeSingapore

The interaction between metabolic dysfunction and inflammation is central to the development of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s ***-related conditions like type 2 diabetes and non-alcoholic fatty liver disease exacerbate this *** lipid accumulation,particularly in the liver,initiates a cascade of inflammatory processes that extend to the brain,influencing critical metabolic regulatory *** and palmitate,key lipid components,along with lipid transporters lipocalin-2 and apolipoprotein E,contribute to neuroinflammation by disrupting blood–brain barrier integrity and promoting *** insulin resistance further exacerbates brain insulin resistance and *** interventions targeting peripheral lipid metabolism and insulin signaling pathways have shown promise in reducing neuroinflammation in animal ***,translating these findings to clinical practice requires further investigation into human *** conclusion,metabolic dysfunction,peripheral inflammation,and insulin resistance are integral to neuroinflammation and *** these complex mechanisms holds potential for identifying novel therapeutic targets and improving outcomes for neurodegenerative diseases.

关键词： Alzheimer’s disease inflammatory cytokines insulin resistance lipid

Spontaneous Orientation Polarization of Anisotropic Equivalent Dipoles Harnessed by Entropy Engineering for Ultra‑Thin Electromagnetic Wave Absorber

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Nano-Micro Letters 2025年第1期17卷 424-438页

作者： Honghan Wang Xinyu Xiao Shangru Zhai Chuang Xue Guangping Zheng Deqing Zhang Renchao che Junye cheng Liaoning Key Lab of Lignocellulose chemistry and BioMaterials Liaoning Collaborative Innovation Center for Lignocellulosic BiorefinerySchool of Light Industry and Chemical EngineeringDalian Polytechnic UniversityDalian 116034People’s Republic of China School of Life Science and Biotechnology Dalian University of TechnologyDalian 116024People’s Republic of China Department of Mechanical Engineering Hong Kong Polytechnic UniversityHung HomKowloonHong Kong 999077People’s Republic of China School of Materials Science and Engineering Qiqihar UniversityQiqihar 161006People’s Republic of China Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Department of Materials Science Shenzhen MSU-BIT UniversityShenzhen 517182People’s Republic of China

The synthesis of carbon supporter/nanoscale high-entropy alloys(HEAs)electromagnetic response composites by carbothermal shock method has been identified as an advanced strategy for the collaborative competition engineering of conductive/dielectric *** migration modes within HEAs as manipulated by the electronegativity,valence electron configurations and molar proportions of constituent elements determine the steady state and efficiency of equivalent ***,enlightened by skin-like effect,a reformative carbothermal shock method using carbonized cellulose paper(CCP)as carbon supporter is used to preserve the oxygencontaining functional groups(O·)of carbonized cellulose fibers(CCF).Nucleation of HEAs and construction of emblematic shell-core CCF/HEAs heterointerfaces are inextricably linked to carbon metabolism induced by O·.Meanwhile,the electron migration mode of switchable electronrich sites promotes the orientation polarization of anisotropic equivalent *** virtue of the reinforcement strategy,CCP/HEAs composite prepared by 35%molar ratio of Mn element(CCP/HEAs-Mn_(2.15))achieves efficient electromagnetic wave(EMW)absorption of−51.35 dB at an ultra-thin thickness of 1.03 *** mechanisms of the resulting dielectric properties of HEAs-based EMW absorbing materials are elucidated by combining theoretical calculations with experimental characterizations,which provide theoretical bases and feasible strategies for the simulation and practical application of electromagnetic functional devices(e.g.,ultra-wideband bandpass filter).

关键词： High-entropy alloys Carbothermal shock Switchable electron migration modes Emblematic shell-core heterointerfaces Ultra-thin thickness

Successful bailout stenting strategy against rare spontaneous retrograde dissection of partially absorbed magnesium-based resorbable scaffold:A case report

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World Journal of Clinical Cases 2021年第5期9卷 1148-1155页

作者： Zhen-Yu Liao Jer-Young Liou Shen-Chang Lin Huei-Fong hung che-Ming Chang Lung-ching chen Su-Kiat Chua Huey-Ming Lo chi-Feng hung Division of Cardiology Department of Internal MedicineShin Kong Wu Ho-Su Memorial HospitalTaipei 11101Taiwan Ph.D.Program in Nutrition and Food Science Fu Jen Catholic UniversityNew Taipei 24205Taiwan School of Medicine Fu Jen Catholic UniversityNew Taipei 24205Taiwan MS Program Transdisciplinary Long-Term Care Fu Jen Catholic UniversityNew Taipei 24205Taiwan Ph.D.Program in Pharmaceutical Biotechnology Fu Jen Catholic UniversityNew Taipei 24205Taiwan

BACKGROUND In the development of coronary stent technology,bioresorbable scaffolds are promising milestones in improving the clinical treatment of coronary artery ***“leave nothing behind”motto is the premise of the fourth revolution in percutaneous coronary intervention(PCI).Studies proving the safety and efficacy of the magnesium-based resorbable scaffolds(MgBRSs)include the BIOSOLVE-I and BIOSOLVE-II trials and the latest BIOSOLVE-IV ***,spontaneous retrograde dissection of a partially absorbed MgBRS may still occur,albeit *** SUMMARY We describe an unusual case of coronary artery disease in a patient who had undergone a successful PCI 8 mo earlier,where an MgBRS was implanted into the left anterior descending artery(LAD)and left circumflex artery with drug-coated balloons for a ramus intermedius branch stenosis to achieve the“leave nothing behind”therapeutic intention and was currently presenting with a gradual worsening of chest *** distal edge vascular response,during subsequent attempts with balloon angioplasty was performed ***,spontaneous retrograde dissection of a partially absorbed MgBRS in the LAD *** bailout stenting was performed with revascularization of the entry and exit sites created by spontaneous dissection and complete sealing of the intramural *** patient recovered well and was discharged after 2 d of *** followed up in August 2020(7 mo later),the patient showed uneventful *** Spontaneous retrograde dissection of a partially absorbed MgBRS was successfully treated using bailout sirolimus-eluting coronary stent strategy.

关键词： Coronary artery disease Percutaneous coronary intervention Magnesium Stents Dissection Case report

On the Current Error Based Sampled-data Iterative Learning Control with Reduced Memory Capacity

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International Journal of Automation and computing 2015年第3期12卷 307-315页

作者： chiang-Ju chien Yu-Chung hung Rong-Hu chi Department of Electronic Engineering Huafan University School of Automation and Electrical Engineering Qingdao University of Science and Technology

The design of iterative learning controller(ILC) requires to store the system input, output or control parameters of previous trials for generating the input of the current trial. In order to apply the iterative learning controller for a real application and reduce the memory size for implementation, a current error based sampled-data proportional-derivative(PD) type iterative learning controller is proposed for control systems with initial resetting error, input disturbance and output measurement noise in this *** proposed iterative learning controller is simple and effective. The first contribution in this paper is to prove the learning error convergence via a rigorous technical analysis. It is shown that the learning error will converge to a residual set if a forgetting factor is introduced in the controller. All the theoretical results are also shown by computer simulations. The second main contribution is to realize the iterative learning controller by a digital circuit using a field programmable gate array(FPGA) chip applied to repetitive position tracking control of direct current(DC) motors. The feasibility and effectiveness of the proposed current error based sampleddata iterative learning controller are demonstrated by the experiment results. Finally, the relationship between learning performance and design parameters are also discussed extensively.

关键词： Iterative learning control current error sampled-data system memory capacity field programmable gate array(FPGA) chip.

A chiral Phosphorous Derivatizing Agent for the Determination of the Enantiomeric Excess of chiral Alcohols, Amines by ^(31)P NMR

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chinese chemical Letters 2001年第10期12卷 907-908页

作者： Kang Ying LI Zheng Hong ZHOU chi hung YEUNG Chu chi TANG State Key Laboratory of Elemento-Organic chemistry Nankai UniversityTianjin 300071 Laboratory of chiral Technology and Department of Applied Biology and chemical Technology The Hong Kong Polytcchnic UniversityHong Kong

A chiral phosphorous derivatizing agent prepared from PCl3 and (S)-BINOL was described. It is used to determine the enantiomeric excess of chiral alcohols and amines by 31P NMR.

关键词： chiral phosphorous derivation chiral alcohols chiral amines enantiomeric excess asymmetric induction.

Rare complication of inflammatory bowel disease-like colitis from glycogen storage disease type 1b and its surgical management:A case report

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World Journal of Clinical Cases 2021年第16期9卷 4081-4089页

作者： Frederick chi-Wai Lui Oswens Siu-hung Lo Department of Surgery LKS Faculty of MedicineThe University of Hong KongHong KongChina

BACKGROUND Glycogen storage disease(GSD)is an autosomal recessive inborn metabolic *** with GSD are prone to hypoglycaemia,hyperlactacidemia and *** type 1b(GSD-1b)patients specifically can develop neutropenia,recurrent bacterial infection and inflammatory bowel disease(IBD).Documentation of the long-term outcomes of surgical management of GSD-1b has been scarce,especially for Asian *** herein describe a case of GSD-1b complicated by IBD-like colitis and coloduodenal *** patient was managed successfully with surgical *** SUMMARY A 20-year-old chinese lady confirmed by genetic testing to have GSD-1b was initially managed with uncooked cornstarch and granulocyte-colony stimulating *** recurrent abdominal symptoms,her condition was treated as clinical“Crohn’s disease”with mesalazine,prednisolone and azathioprine *** showed a tight stricture at the hepatic *** computerized tomographic colonography revealed a phlegmon at the ileocaecal region with a suspected coloduodenal *** an exploratory laparotomy was performed and severe colitis at the ascending colon with coloduodenal fistula was *** hemicolectomy with primary anastomosis and repair of the duodenum were *** management of complications from GSD-1b associated IBD-like colitis has rarely been ***-line treatment would usually be *** intervention like hemicolectomy is mainly reserved for refractory *** Surgical management of coloduodenal fistula in GSD-1b patients is a feasible and safe option when failed conservative management.

关键词： Glycogen storage disease Coloduodenal fistula Inflammatory bowel diseaselike colitis Case report Perioperative management

Glasgow prognostic score after concurrent chemoradiotherapy is a prognostic factor in advanced head and neck cancer

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chinese Journal of Cancer Research 2017年第3期29卷 172-178页

作者： Pei-hung Chang cheng-Hsu Wang Eric Yen-Chao chen Shih-Wei Yang Wen-chi Chou Jason chia-Hsun Hsieh Feng-che Kuan Kun-Yun Yeh Division of Hemato-oncology Department of Internal MedicineChang Gung Memorial HospitalKeelung&Chang Gung UniversityCollege of MedicineKeelung 20445 TaiwanChina Cancer Center Chang Gung Memorial HospitalKeelung 20445TaiwanChina Department of Radiation Oncology Chang Gung Memorial HospitalKeelung&Chang Gung UniversityCollege of MedicineKeelung 20445TaiwanChina Otolaryngology Head and Neck SurgeryChang Gung Memorial HospitalKeelung&Chang Gung UniversityCollege of MedicineKeelung 20445TaiwanChina Division of Medical Oncology Department of Internal MedicineChang Gung Memorial Hospital at LinkouTaoyuan 33305TaiwanChina Department of Hematology and Oncology Department of MedicineChang-Gung Memorial HospitalChiayi 61363TaiwanChina

Objective: This study aims to evaluate the impact and potential prognostic roles of the pre- and post-treatment Glasgow prognostic score (GPS) and the change thereof in patients with advanced head and neck cancer undergoing concurrent chemoradiotherapy (CCRT). Methods: We collected GPS and clinicopathological data of 139 stage III, IVA, and IVB head and neck cancer patients who underwent CCRT between 2008 and 2011. Their GPSs pre- and post-CCRT and the change thereof were analyzed for correlations with recurrence and survival. Results: The GPS changed in 72 (51.8%) patients, with worse scores observed post-CCRT in 65 (90.3%) of the GPS changed patients. Patients in the improved GPS group showed a tendency toward better survival. From the multivariate analysis, the post-CCRT GPS level was an independent prognostic factor in addition to tumor stage. Conclusions: After CCRT, a high GPS was revealed to be an important predictor of survival for advanced head and neck cancer.

关键词： Glasgow prognostic score (GPS) head and neck cancer chemoradiation inflammation cachexia nutrition

Clinical significance of skin rash in dengue fever:A focus on discomfort,complications,and disease outcome

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Asian Pacific Journal of Tropical Medicine 2016年第7期9卷 693-697页

作者： Hsin-Wei Huang Han-chi Tseng chih-hung Lee hung-Yi Chuang Shang-hung Lin Department of Dermatology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Departments of Environmental and Occupational Medicine Kaohsiung Medical University Hospital Department of Public Health Kaohsiung Medical University

Objective:To assess whether the cutaneous features in patients with dengue fever are associated with abnormal blood biochemistry,complications,and poor disease ***:Forty five patients with dengue fever were identified at a medical center in Kaohsiung,Taiwan,from September to November *** cases were exclusively caused by type 1 dengue *** were classified into two groups,based on the presence or absence of skin rash,and their rash was subclassified into maculopapular,morbilliform,and petechial *** symptoms,laboratory data,disease outcome,and complications were compared between the two ***:Thirty two patients with dengue fever developed skin rash(SP group,n=32) while the rest of 13 did not(SN group,n=13).The patient numbers in the maculopapular,morbilliform,and petechial group were 4,21,and 7,*** SP group was younger(P=0.001),experienced more pruritus(P=0.008) and more swollen palms/soles(P=0.015) than the SN ***,the SN group had greater genital mucosa involvement(P=0.008),higher platelet transfusion rate(P=0.003),and lower hemoglobin and hematocrit levels(P=0.030) than the SP *** with morbilliform lesions had a higher incidence of palm/sole swelling,less genital mucosal involvement,and a lower platelet transfusion rate than did patients with maculopapular or petechial ***:Cutaneous manifestations provide an important clue to dengue *** patients with dengue fever,those with skin rash tend to have itching and swelling of the palms/soles,however,those without skin rash tend to have more complications and poor disease outcomes.

关键词： Dengue Exanthema Pruritus Serology

Simultaneous bilateral floating knee:A case report

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World Journal of Clinical Cases 2022年第28期10卷 10172-10179页

作者： chi-Ming Wu hung-En Liao Shou-Jen Lan Department of Orthopaedic Jen-Ai HospitalTaichung 42481Taiwan Department of Orthopaedic National Defense Medical CenterTaipei 11490Taiwan Department of Healthcare Administration Asia UniversityTaichung 41354Taiwan Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung 40402Taiwan School of Medical Science Putian UniversityPutian 351100Fujian ProvinceChina

BACKGROUND The phrase “floating knee is a flail knee joint,” referring to ipsilateral femoral and tibial fractures,was first used by Blake and Mc Bryde in *** condition is often caused by a high-energy trauma with often extensive injury to the soft tissues,and is accompanied by life-threatening systemic complications,including head,chest or abdominal injuries and a high incidence of fat *** knee is a severe and uncommon injury *** SUMMARY A 27-year-old man sustained multiple injuries when the electric motorcycle he was riding was hit by a *** injuries included traumatic hypovolemic shock,comminuted and open type II fractures of the left femoral shaft,fracture of the right femoral shaft,comminuted fracture of the bilateral tibial and fibular shaft,and multiple lacerations and abrasions on his forehead,lower lip,neck and *** diagnosis was simultaneous bilateral floating knee complicated with soft tissue *** emergency treatment and the exclusion of life-threating complications,open reduction and internal fixation were successfully performed using plates and screws in the bilateral femoral and tibial *** Simultaneous bilateral floating knee is a rare and severe injury *** treatment is challenging,and *** present a case report of a young adult who suffered from bilateral floating knees during road traffic *** also offer our treatment experience of this complex injury and review past literature.

关键词： Floating knee Femoral and tibial fractures High-energy trauma Life-threatening complications Fat embolism syndrome Case report