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Energy and Built Environment 2024年第1期5卷 97-109页

作者： Xueqiong He chi feng Huibo Zhang School of Design Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Research Institute of Building Sciences Group Co. LtdShanghai 200032China School of Architecture and Urban Planning Chongqing UniversityChongqing 400045China

The moisture performance of building envelopes largely depends on the building materials,construction tech-niques,and exposure loads from the indoor and outdoor regions.A ventilated air interlayer placed in a wall can help dehumidify the wall and indoor *** paper presents an experimental study of the heat,air,and moisture variations within the envelope wall of a chamber featuring different air interlayer settings under real outdoor air conditions during the summer of 2020 in Shanghai,***-developed humidity-controlling building mate-rials were applied to the inner building ***,humidity,wind velocity,and heat-flow sensors were placed at different positions in the middle of the *** parameters were measured and recorded in real-time under three working conditions:humidification,dehumidification,and *** experimental results show that under the ventilation working conditions,moisture content of 0.52 kg can be removed after a 2-h air layer ventilation,which can benefit the design strategy for the humidification and ventilation of dehu-midification walls.

关键词： Ventilated wall Heat and humidity coupling transfer Moisture-buffering materials Experimental research

基于自动驾驶车辆调度的停车系统收费策略优化

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浙江大学学报（工学版） 2024年第1期58卷 87-95页

作者：冯驰梅振宇衢州学院机械工程学院浙江衢州324000 浙江省空气动力装备技术重点实验室浙江衢州324000 浙江大学智能交通研究所浙江杭州310058 浙江大学平衡建筑研究中心浙江杭州310058

针对有人驾驶车辆与自动驾驶车辆共存的停车系统,设计基于自动驾驶车辆调度的停车系统收费策略,以提升停车系统运行效率.该策略在停车场无可用停车泊位但存在自动驾驶车辆时向有人驾驶车辆提供自动驾驶车辆调度服务,停车系统向有人驾驶... 详细信息

针对有人驾驶车辆与自动驾驶车辆共存的停车系统,设计基于自动驾驶车辆调度的停车系统收费策略,以提升停车系统运行效率.该策略在停车场无可用停车泊位但存在自动驾驶车辆时向有人驾驶车辆提供自动驾驶车辆调度服务,停车系统向有人驾驶车辆收取一定调度费用后,通过在多个停车场间调度若干自动驾驶车辆,为有人驾驶车辆在其目标停车场创造可用停车泊位.各停车场的调度费用会影响有人驾驶车辆用户的停车选择,进而影响停车系统的运行效率,构建基于智能体的停车仿真模型,采用遗传算法差异化地设置系统内各个停车场的停车调度收费方案.仿真结果显示,采用基于自动驾驶车辆调度的差异化收费策略,可以有效地减少有人驾驶车辆用户的行驶时间、步行时间、总出行时间及行驶里程,增加停车系统营收,降低社会成本,有效地缓解停车矛盾.

关键词：停车调度停车收费自动驾驶车辆基于智能体模型停车策略

Trametinib boosts palbociclib’s efficacy in breast cancer via autophagy inhibition

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Oncology Research 2024年第7期32卷 1197-1207页

作者： ANGUO WU JIAO YAN TING SU chi feng XIN LONG YIRU PAN RUPEI YE TIAN XIA HANAN LONG JIANMING WU XIULI XIAO Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia MedicaKey Laboratory of Medical Electrophysiology of Ministry of EducationSchool of PharmacySouthwest Medical UniversityLuzhou646000China The Department of Pathology The Affiliated Hospital of Southwest Medical UniversityLuzhou646000China The Department of Pathology Mianyang Central HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaMianyang621000China The Department of Pathology Yongchuan Hospital of Chongqing Medical UniversityChongqing402160China School of Basic Medical Sciences Southwest Medical UniversityLuzhou646000China School of Clinical Medical Sciences Southwest Medical UniversityLuzhou646000China

Breast cancer,a predominant global health issue,requires ongoing exploration of new therapeutic ***(PAL),a well-known cyclin-dependent kinase(CDK)inhibitor,plays a critical role in breast cancer *** its efﬁcacy is recognized,the interplay between PAL and cellular autophagy,particularly in the context of the RAF/MEK/ERK signaling pathway,remains insufﬁciently *** study investigates PAL’s inhibitory effects on breast cancer using both in vitro(MCF7 and MDA-MB-468 cells)and in vivo(tumor-bearing nude mice)*** at elucidating the impact of PAL on autophagic processes and exploring the potential of combining it with trametinib(TRA),an MEK inhibitor,our research seeks to address the challenge of PAL-induced drug ***ﬁndings reveal that PAL signiﬁcantly decreases the viability of MCF7 and MDA-MB-468 cells and reduces tumor size in mice while showing minimal cytotoxicity in MCF10A ***,PAL also induces protective autophagy,potentially leading to drug resistance via the RAF/MEK/ERK pathway *** TRA effectively neutralized this autophagy,enhancing PAL’s anti-tumor efﬁcacy.A combination of PAL and TRA synergistically reduced cell viability and proliferation,and in vivo studies showed notable tumor size *** conclusion,the PAL and TRA combination emerges as a promising strategy for overcoming PAL-induced resistance,offering a new horizon in breast cancer treatment.

关键词： Palbociclib Trametinib Protective autophagy RAF/MEK/ERK MCF7 MDA-MB-468

Nonlinear Seebeck and Peltier effects in a Majorana nanowire coupled to leads

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chinese Physics B 2024年第7期33卷 547-552页

作者：迟锋刘佳付振国刘黎明易子川 School of Electronic and Information Engineering UESTC of ChinaZhongshan InstituteZhongshan 528400China School of Science Inner Mongolia University of Science and TechnologyBaotou 014010China Institute of Applied Physics and Computational Mathematics Beijing 100088China

We theoretically study nonlinear thermoelectric transport through a topological superconductor nanowire hosting Majorana bound states(MBSs) at its two ends, a system named as Majorana nanowire(MNW). We consider that the MNW is coupled to the left and right normal metallic leads subjected to either bias voltage or temperature gradient. We focus our attention on the sign change of nonlinear Seebeck and Peltier coefficients induced by mechanisms related to the MBSs, by which the possible existence of MBSs might be proved. Our results show that for a fixed temperature difference between the two leads, the sign of the nonlinear Seebeck coefficient(thermopower) can be reversed by changing the overlap amplitude between the MBSs or the system equilibrium temperature, which are similar to the cases in linear response regime. By optimizing the MBS–MBS interaction amplitude and system equilibrium temperature, we find that the temperature difference may also induce sign change of the nonlinear thermopower. For zero temperature difference and finite bias voltage, both the sign and magnitude of nonlinear Peltier coefficient can be adjusted by changing the bias voltage or overlap amplitude between the MBSs. In the presence of both bias voltage and temperature difference, we show that the electrical current at zero Fermi level and the states induced by overlap between the MBSs keep unchanged, regardless of the amplitude of temperature difference. We also find that the direction of the heat current driven by bias voltage may be changed by weak temperature difference.

关键词： quantum dot nonlinear Seebeck coefficient Peltier coefficient Majorana bound states sign change

Radiative cooling for long-term building energy efficiency:An experimental comparison of seven coatings

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National Science Open 2024年第3期3卷 50-69页

作者： Yue He Biao Lu Jinzhong Fang Yue Lei Shan Gao chi feng School of Architecture and Urban Planning Chongqing University Key Laboratory of New Technology for Construction of Cities in Mountain Area Ministry of EducationChongqing University

Radiative cooling coatings are widely used owing to their excellent cooling performance and energy ***,there is a lack of comprehensive research on their weather resistance,long-term performance and effects on building *** fill this research gap,seven coatings were selected for experimental observation and simulation *** results revealed noticeable differences among different coatings regarding anti-aging properties,cooling performance and building load *** coatings exhibited yellowing,cracking and peeling after weathering tests,accompanied by a decline in their radiative ***-term tests showed that the cooling performance of all coatings gradually decreased due to natural aging,and the rate of decline was proportional to the weathering of the *** load simulations revealed the potential effect of coating selection on cooling and heating loads,thereby suggesting that different coatings should be selected based on actual usage scenarios in different climatic zones.

关键词： radiative cooling coating weather resistance long-term cooling performance building load

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多孔材料毛细滞后现象研究综述

材料导报 2024年第12期38卷 112-121页

作者：朱子健胡鹏博冯驰重庆大学建筑城规学院重庆400045 重庆大学山地城镇建设与新技术教育部重点实验室重庆400045

毛细滞后现象指在一定水势下,多孔材料放湿过程的含湿量普遍高于吸湿过程的含湿量,即多孔材料在同一个水势下对应着多个含湿量。在土木建筑、食品科学和土壤科学等领域的工程实践中,往往因忽略毛细滞后现象而无法准确地计算和控制多孔... 详细信息

毛细滞后现象指在一定水势下,多孔材料放湿过程的含湿量普遍高于吸湿过程的含湿量,即多孔材料在同一个水势下对应着多个含湿量。在土木建筑、食品科学和土壤科学等领域的工程实践中,往往因忽略毛细滞后现象而无法准确地计算和控制多孔材料的含湿量,进而给建筑围护结构热湿传递控制、食品的营养与保鲜以及土壤的结构稳定等方面带来负面影响。针对上述现象,本文总结了毛细滞后现象的产生原因、实验研究方法以及预测模型,旨在更加全面深刻地理解多孔材料的储湿机理,为建立更精确的描述多孔材料含湿量与水势关系的数学物理模型提供参考。

关键词：毛细滞后多孔材料保水曲线预测模型

揭示氨对正己酸生产影响的机制——影响途径、关键酶和微生物

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Engineering 2024年第4期35卷 180-190页

作者： Qing-Lian Wu Ke-Xin Yuan Wei-Tong Ren Lin Deng Hua-Zhe Wang Xiao-chi feng He-Shan Zheng Nan-Qi Ren Wan-Qian Guo State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150090China College of Architecture and Environment Sichuan UniversityChengdu 610065China State Key Laboratory of Urban Water Resource and Environment School of Civil and Environmental EngineeringHarbin Institute of Technology(Shenzhen)Shenzhen 518055China College of Chemistry and Chemical Engineering Qiqihar UniversityQiqihar 161006China

n-Caproate,which is produced via chain elongation(CE)using waste biomass,can supply various fossilderived products,thus advancing the realization of carbon *** released from the degradation of nitrogen-rich waste biomass can act as a nutrient or an inhibitor in anaerobic bioprocesses,including CE,with the distinction being primarily dependent on its ***,the optimal concentration of ammonia and the threshold of toxicity for open-culture n-caproate production using ethanol as an electron donor,along with the underlying mechanisms,remain *** study revealed that the optimal concentration of ammonia for n-caproate production was 2.0 g∙L^(-1),whereas concentrations exceeding this threshold markedly suppressed the CE *** of the mechanism revealed the involvement of two forms of ammonia(i.e.,ammonium ions and free ammonia)in this inhibitory *** ammonia levels(5.0 g∙L^(-1))induced excessive ethanol oxidation and suppressed the reverse β-oxidation(RBO)process,directly leading to the enhanced activities of enzymes(phosphotransacetylase and acetate kinase)responsible for acetate formation and diminished activities of butyryl-coenzyme A(CoA):acetyl-CoA transferase,caproyl-CoA:butyryl-CoA transferase,and caproyl-CoA:acetyl-CoA transferase that are involved in the syntheses of n-butyrate and ***,the composition of the microbial community shifted from Paraclostridium dominance(at 0.1 g∙L^(-1)ammonia)to a co-dominance of Fermentimonas,Clostridium sensu stricto 12,and Clostridium sensu stricto 15 at 2.0 g∙L^(-1)***,these CE-functional bacteria were mostly absent in the presence of excessive ammonia(5.0 g∙L^(-1)ammonia).Metagenomic analysis revealed the upregulation of functions such as RBO,fatty acid synthesis,K^(+)efflux,adenosine triphosphatase(ATPase)metabolism,and metal cation export in the presence of 2.0 g∙L^(-1)ammonia,collectively contributing to enhanced n-caproate produc

关键词： Ammonia inhibition Medium chain fatty acids n-Caproate Enzyme Metagenomics

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浅析电力营销信息化建设

基于MODIS影像的2016—2017年东海赤潮高发期水体时空分布及其气象控制因子分析

科学与信息化 2024年第2期 139-141页

作者：沈沐洋冯驰国网江苏省电力有限公司常州供电分公司江苏常州 213000

在社会经济迅猛发展的过程中,电力事业迎来了新的发展阶段,同时也促使行业竞争越来越激烈,给电力营销工作带来了严峻的挑战.面对这样的形势,传统的管理方式已经不能满足时代发展需求,因此,要不断加强创新与提升工程质量.基于此,本文阐... 详细信息

在社会经济迅猛发展的过程中,电力事业迎来了新的发展阶段,同时也促使行业竞争越来越激烈,给电力营销工作带来了严峻的挑战.面对这样的形势,传统的管理方式已经不能满足时代发展需求,因此,要不断加强创新与提升工程质量.基于此,本文阐述了电力营销信息化的重要作用,对智能电网背景下电力营销信息化建设存在的问题进行了分析,并提出了加强电力营销信息化建设的策略.

关键词：电力营销管理应用信息系统系统建设

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应用海洋学学报 2024年第1期43卷 95-105页

作者：李晨映冯驰梅琨苏州科技大学地理科学与测绘工程学院江苏苏州215009

近年来,东海区域赤潮灾害频发,对沿海地区的经济发展和海洋生态环境造成了极大的破坏。本研究基于赤潮暴发年2016—2017年夏季MODIS影像数据,采用半经验多光谱识别算法对东海夏季赤潮暴发期的水体类型分布特征进行反演。结果表明,赤潮... 详细信息

近年来,东海区域赤潮灾害频发,对沿海地区的经济发展和海洋生态环境造成了极大的破坏。本研究基于赤潮暴发年2016—2017年夏季MODIS影像数据,采用半经验多光谱识别算法对东海夏季赤潮暴发期的水体类型分布特征进行反演。结果表明,赤潮高发期东海水体类型从近岸向开阔海域呈现浑浊水体-赤潮水体-混合水体-干净水体的时空分布特征。其中,硅藻和甲藻赤潮水体在空间分布上具有相互演替变化的特征。此外,通过对浙江省近岸的大陈站、石浦站和嵊泗站3个站点的气象因子进行主成分分析发现,气温、风速和天空云量对赤潮的生消演替起着积极的促进作用。

关键词：海洋物理学赤潮 MODIS影像时空演变水体分类气象因子东海

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基于GWO-VMD的涡轮叶片特征提取

哈尔滨商业大学学报（自然科学版） 2024年第4期40卷 387-396页

作者：冯驰唐林伊哈尔滨工程大学信息与通信工程学院哈尔滨150001

燃气轮机涡轮叶片是燃气轮机的重要组成部分,长期工作在高温、高压、高速的恶劣环境下,健康的涡轮叶片能够保证燃气轮机高效率地工作.温度是反映燃气轮机涡轮叶片状态的关键参数,在涡轮叶片发生涂层脱落、断裂等故障时,叶片表面温度会... 详细信息

燃气轮机涡轮叶片是燃气轮机的重要组成部分,长期工作在高温、高压、高速的恶劣环境下,健康的涡轮叶片能够保证燃气轮机高效率地工作.温度是反映燃气轮机涡轮叶片状态的关键参数,在涡轮叶片发生涂层脱落、断裂等故障时,叶片表面温度会发生变化,为了衡量涡轮叶片的健康状态,采用了温度这一叶片质量的重要指标,对数据预处理并进行特征提取,将涡轮叶片特征聚类.基于GWO-VMD提取叶片温度信号经分解后各IMF分量的4种熵特征,使用PCA对提取到的叶片特征进行降维,将降维后的特征送入FCM聚类算法,通过SSE和轮廓系数得到最佳聚类个数,实现对叶片特征的聚类.聚类效果表明,该特征提取方法能够较好地区分不同涡轮叶片的健康状态,为涡轮叶片健康监测的研究提供了一定思路.

关键词：涡轮叶片特征提取灰狼优化算法变分模态分解模糊C均值聚类