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Hypertension and Heart Failure as Predictors of Mortality in an Adult Congenital Heart Defect Population

Congenital Heart Disease 2021年第4期16卷 333-355页

作者： cheryl raskind-hood Kashaine A.Gray Jayne Morgan Wendy M.Book Department of Epidemiology Emory School of Public HealthAtlantaGeorgiaUSA Department of Public Health Mercer University College of Health ProfessionsAtlantaGeorgiaUSA Division of Cardiovascular Research Piedmont HospitalAtlantaGeorgiaUSA Division of Cardiology Emory University School of MedicineAtlantaGeorgiaUSA

Early intervention to prevent premature mortality is vital for adults with congenital heart defects(CHD).Anatomic complexity and comorbid conditions are thought to contribute to CHD *** hypertension(HTN)and heart failure(HF)are the comorbid conditions among the most prevalent causes of death in the United States,and commonly accompany CHD,it is crucial to evaluate whether they are reliable predictors of mortality for adults with CHD(ACHD)independent of anatomic CHD complexity.A retrospective cross-sectional analysis of ACHD,aged 18–64,with concomitant HTN and/or HF and at least one health care encounter during 2008–2010 were *** 5,397 ACHD patients(18.3%HTN without HF,4.4%HF without HTN,8.3%with both),3.0%died(n=163)during the study ***,the sample was 45.1%white,61.4%female,and 29.0%had a complex *** those who died,23.3%had HTN without HF,17.2%had HF without HTN,and 42.3%had *** analyses revealed that older age,male gender,black race,and having public health insurance were associated with increased mortality during the three-year study period compared to ACHD patients who were younger,female gender,white race,and covered by private health *** patients diagnosed with non-complex CHD lesions(i.e.,shunts,valves,or shunts+valves)were at greater risk of dying compared to those with severe complex *** CHD type was assessed separately,those with valve lesions were more likely to die compared to those with complex CHD *** adjustment for age,gender,race,insurance and CHD complexity,ACHD patients with HF,with or without HTN,were equally likely to die during the study ***,ACHD patients with HF,without or without HTN,who had valve defects were more likely to die during the three-year study period compared to patients with complex CHDs.

关键词： Congenital heart defect risk factors hypertension heart failure mortality

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