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皮革制作与环保科技 2024年第1期5卷 137-138,141页

作者：尹振珑林成豪济南市人防建筑设计研究院有限责任公司山东济南250000 水发规划设计有限公司山东济南250000

本文通过列举农村水污染治理的必要性,强调水污染治理对改善农村生态环境、提升农民生活品质、建设美丽中国的重要性,并提出农村水污染治理的原则与治理模式,旨在推动农村水污染治理。

关键词：水污染治理美丽乡村农村生态环境

基于CNN-Transformer混合构架的轻量图像超分辨率方法

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网络安全与数据治理 2024年第3期43卷 27-33页

作者：林承浩吴丽君福州大学物理与信息工程学院福建福州350108

针对基于混合构架的图像超分模型通常需要较高计算成本的问题,提出了一种基于CNN-Transformer混合构架的轻量图像超分网络STSR(Swin-Transformer-based Single Image Super-Resolution)。首先,提出了一种并行特征提取的特征增强模块(Fea... 详细信息

针对基于混合构架的图像超分模型通常需要较高计算成本的问题,提出了一种基于CNN-Transformer混合构架的轻量图像超分网络STSR(Swin-Transformer-based Single Image Super-Resolution)。首先,提出了一种并行特征提取的特征增强模块(Feature Enhancement Block, FEB),由卷积神经网络(Convolutional Neural Network, CNN)和轻量型Transformer网络并行地对输入图像进行特征提取,再将提取到的特征进行特征融合。其次,设计了一种动态调整模块(Dynamic Adjustment, DA),使得网络能根据输入图像来动态调整网络的输出,减少网络对无关信息的依赖。最后,采用基准数据集来测试网络的性能,实验结果表明STSR在降低模型参数量的前提下仍然保持较好的重建效果。

关键词：图像超分辨率轻量化卷积神经网络 Transformer

Tetraphenylethene-based hole transporting material for highly efficient and stable perovskite solar cells

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Science China Chemistry 2024年第6期67卷 2009-2015页

作者： Peng Wang Pei Yuan chenghao Ge Rongjun Zhao lin Xie Yong Hua School of Materials and Energy Yunnan UniversityKunming650091China

2,2,7,7-Tetrakis-(N,N-di-p-methoxyphenylamine)-9,9-spirobifluorene(Spiro-OMeTAD)has been identified as the most widely used and effective hole transporting material(HTM)in perovskite solar cells(PSCs).However,the complicated multistep synthesis and low intrinsic hole mobility of Spiro-OMe TAD limit its commercialized ***,developing highly efficient HTMs with less synthetic steps becomes increasingly ***,understanding hot carriers transfer dynamics at the interface of perovskite layer and hole transport layer is crucial for further enhancing PSCs performance towards Shockley-Queisser limit,which still lacks full investigation to ***,a new HTM based on tetraphenylethene(WP1)was successfully synthesized by a simple one-step reaction *** was found that WP1-based HTM exhibits more matched energy level,higher hole mobility and conductivity than those of the control Spiro-OMe *** femtosecond transient absorption results reveal that the transfer rate of hot holes in perovskite/WP1 sample is four times higher than that of perovskite/Spiro-OMeTAD,thereby helping enhance the device ***,the efficiency of PSCs is enhanced to 24.04%(WP1)from 22.85%(Spiro-OMeTAD).Moreover,the un-encapsulated device prepared with WP1 exhibits better long-term stability,retaining 87%of its initial PCE value after storing for 72 days under air environment,while the reference device shows76%of its initial *** work indicates that simple tetraphenylethene-based organic small molecule could be a very promising HTM candidate for highly efficient PSCs,and gives some significant insights for understanding intrinsic hot carriers transfer dynamics in device.

关键词： tetraphenylethene hole transporting material perovskite solar cells mobility hot carrier

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Immune landscape and response to oncolytic virus-based immunotherapy

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Frontiers of Medicine 2024年第3期18卷 411-429页

作者： Chaolong lin Wenzhong Teng Yang Tian Shaopeng Li Ningshao Xia chenghao Huang State Key Laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine LaboratoryDepartment of Laboratory MedicineSchool of Public HealthXiamen UniversityXiamen361102China National Institute of Diagnostics and Vaccine Development in Infectious Diseases State Key Laboratory of Molecular Vaccinology and Molecular DiagnosticsXiamen UniversityXiamen361102China

Oncolytic virus(OV)-based immunotherapy has emerged as a promising strategy for cancer treatment,offering a unique potential to selectively target malignant cells while sparing normal ***,the immunosuppressive nature of tumor microenvironment(TME)poses a substantial hurdle to the development of OVs as effective immunotherapeutic agents,as it restricts the activation and recruitment of immune *** review elucidates the potential of OV-based immunotherapy in modulating the immune landscape within the TME to overcome immune resistance and enhance antitumor immune *** examine the role of OVs in targeting specific immune cell populations,including dendritic cells,T cells,natural killer cells,and macrophages,and their ability to alter the TME by inhibiting angiogenesis and reducing tumor ***,we explore strategies to optimize OV-based drug delivery and improve the efficiency of OV-mediated *** conclusion,this review offers a concise and comprehensive synopsis of the current status and future prospects of OV-based immunotherapy,underscoring its remarkable potential as an effective immunotherapeutic agent for cancer treatment.

关键词： oncolytic virus immunotherapy immunotherapeutic agents immune landscape

Cytokine storm promoting T cell exhaustion in severe COVID-19 revealed by single cell sequencing data analysis

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Precision Clinical Medicine 2022年第2期5卷 87-99页

作者： Minglei Yang chenghao lin Yanni Wang Kang Chen Yutong Han Haiyue Zhang Weizhong Li Zhongshan School of Medicine Sun Yat-sen UniversityGuangzhou 510080China Center for Precision Medicine Sun Yat-sen UniversityGuangzhou 510080China Key Laboratory of Tropical Disease Control of Ministry of Education Sun Yat-Sen UniversityGuangzhou 510080China

Background:Evidence has suggested that cytokine storms may be associated with T cell exhaustion(TEX)in ***,the interaction mechanism between cytokine storms and TEX remains ***:With the aim of dissecting the molecular relationship of cytokine storms and TEX through single-cell RNA sequencing data analysis,we identified 14 cell types from bronchoalveolar lavage fluid of COVID-19 patients and healthy *** observed a novel subset of severely exhausted CD8 T cells(Exh T_CD8)that co-expressed multiple inhibitory receptors,and two macrophage subclasses that were the main source of cytokine storms in ***:Correlation analysis between cytokine storm level and TEX level suggested that cytokine storms likely promoted TEX in severe ***–cell communication analysis indicated that cytokines(***10,CXCL11,CXCL2,CCL2,and CCL3)released by macrophages acted as ligands and significantly interacted with inhibitory receptors(***3,DPP4,CCR1,CCR2,and CCR5)expressed by Exh T_*** interactions formed the cytokine–receptor axes,which were also verified to be significantly correlated with cytokine storms and TEX in lung squamous cell ***:Cytokine storms may promote TEX through cytokine-receptor axes and be associated with poor prognosis in *** cytokine-receptor axes may reverse *** finding provides novel insights into TEX in COVID-19 and new clues for cytokine-targeted immunotherapy development.

关键词： COVID-19 immune exhaustion cytokine storm single-cell sequencing data analysis T cell immune checkpoint

郯庐断裂带苏皖段重力变化的多尺度分解与构造活动分析

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大地测量与地球动力学 2019年第9期39卷 884-889页

作者：林承灏黎哲君徐如刚袁泉安徽省地震局合肥市230031 安徽省地震局郯庐断裂带中南段重点研究室合肥市230031

基于多期绝对重力与相对重力联测资料,获取不同时空尺度的郯庐断裂带苏皖段及周边地区重力场动态变化,采用小波多尺度分解方法计算不同深度的重力变化,结合区域地质构造,从深度层次的横向变化与时间尺度的纵向变化2个方面进行分析。结... 详细信息

基于多期绝对重力与相对重力联测资料,获取不同时空尺度的郯庐断裂带苏皖段及周边地区重力场动态变化,采用小波多尺度分解方法计算不同深度的重力变化,结合区域地质构造,从深度层次的横向变化与时间尺度的纵向变化2个方面进行分析。结果表明,研究区重力变化主要由中、上地壳密度变化或断裂构造活动引起。沿郯庐断裂带苏皖段走向断裂活动分布不均,受周边深大断裂带交切作用的影响表现出明显的分段活动特征。淮阴-响水口断裂、滁河断裂等深大活动断裂带构造活动对局部重力变化具有一定的控制作用,沿断裂带走向分布有明显的重力变化梯度带;郯庐断裂带郯城-泗县段、大别山构造带霍山-六安及江苏溧阳-镇江地区在小波细节动态变化中存在重力变化梯度带异常区,但强度不高,考虑到多条深大断裂交切于此,后期需要重点关注。

关键词：郯庐断裂带苏皖段重力变化小波多尺度分析构造活动

Adaptive Noise Detector and Partition Filter for Image Restoration

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Computers, Materials & Continua 2023年第5期75卷 4317-4340页

作者： Cong lin chenghao Qiu CanWu Siling Feng Mengxing Huang School of Information and Communication Engineering Hainan UniversityHaikou570228China State Key Laboratory of Marine Resource Utilization in South China Sea HainanUniversityHaikou570228China

The random-value impulse noise(RVIN)detection approach in image denoising,which is dependent on manually defined detection thresholds or local window information,does not have strong generalization performance and cannot successfully cope with damaged pictures with high noise *** fusion of the K-means clustering approach in the noise detection stage is reviewed in this research,and the internal relationship between the flat region and the detail area of the damaged picture is thoroughly explored to suggest an unique two-stage method for gray image *** on the concept of pixel clustering and grouping,all pixels in the damaged picture are separated into various groups based on gray distance similarity features,and the best detection threshold of each group is solved to identify the *** the noise reduction step,a partition decision filter based on the gray value characteristics of pixels in the flat and detail areas is *** the noise pixels in flat and detail areas,local consensus index(LCI)weighted filter and edge direction filter are designed respectively to recover the pixels damaged by the *** experimental results show that the accuracy of the proposed noise detection method is more than 90%,and is superior to most mainstream *** the same time,the proposed filtering method not only has good noise reduction and generalization performance for natural images and medical images with medium and high noise but also is superior to other advanced filtering technologies in visual effect and objective quality evaluation.

关键词： Image denoising pixel clustering normalization subregion filtering medical image

潘集矿区煤层层滑构造特征及其与潘集背斜的关系

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煤田地质与勘探 2013年第3期41卷 1-6页

作者：乐琪浪林承灏杨为民陈萍中国地质调查局水文地质环境地质调查中心河北保定071051 安徽理工大学地球与环境学院安徽淮南232001 中国地质科学院地质力学研究所北京100081

通过对潘集矿区构造特征及矿区构造应力场分析,对潘集背斜两翼的潘北井田和潘一井田中的层滑构造进行研究,将矿区分为10个主层滑区及29个层滑亚区。研究结果显示:矿区层滑构造的产生与南北向主应力场及大型断裂所构建的局部应力场密切相... 详细信息

通过对潘集矿区构造特征及矿区构造应力场分析,对潘集背斜两翼的潘北井田和潘一井田中的层滑构造进行研究,将矿区分为10个主层滑区及29个层滑亚区。研究结果显示:矿区层滑构造的产生与南北向主应力场及大型断裂所构建的局部应力场密切相关;层滑构造导致矿区形成近东西向薄煤带,发育以Ⅱ和Ⅲ类型为主的构造煤;层滑构造多发育在背斜两翼,且以断滑型和揉皱型为主,而在背斜核部则以断裂型为主;在纵向上,层滑构造类型也具有明显的规律性,在相对浅的区域,层滑构造以断裂型为主,往下是断滑型,而在较深部位及断裂构造交汇处,则主要表现为揉皱型。

关键词：煤层层滑构造潘集背斜发育特征分布规律

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CG-5型重力仪漂移特性与分时段平差处理

大地测量与地球动力学 2020年第6期40卷 655-660页

作者：梁霄徐如刚林承灏储飞肖伟鹏王飞安徽省地震局合肥市300312 安徽省地震局郯庐断裂带中南段重点研究室合肥市230031

详细分析了4台CG-5型重力仪的静、动态漂移特性,结果发现,单次的静态测试结果中,CG-5型重力仪静态漂移呈很好的线性上升趋势,但划分不同时间尺度,每个时间段的仪器漂移率仍存在一定差异。同时,静态漂移率也存在长期变化的特征,不同测期C... 详细信息

详细分析了4台CG-5型重力仪的静、动态漂移特性,结果发现,单次的静态测试结果中,CG-5型重力仪静态漂移呈很好的线性上升趋势,但划分不同时间尺度,每个时间段的仪器漂移率仍存在一定差异。同时,静态漂移率也存在长期变化的特征,不同测期CG-5型重力仪的漂移率差异较大:刚出厂时,CG-5型重力仪的漂移率变化幅度较大;随着时间变化,幅度逐渐减小,最终在一定区间内震荡。4台仪器的动态漂移率与仪器空间变化关系不密切,但仪器间的漂移特性在静态漂移率的长期变化、上下山的动态实验和单个测期各测线的动态漂移率变化中都表现出较为一致的变化趋势。基于以上认识,采用分时段平差的方法对观测数据进行分段漂移改正,改正后各台仪器和总体的联测精度指标均有所提高。

关键词： CG-5型重力仪静态漂移率动态漂移率漂移改正平差

基于卫星遥感的氮氧化物排放快速反演方法比较

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地球科学进展 2024年第3期39卷 269-278页

作者：王思杰林金泰孔浩张宇航徐呈浩李春锦任芳萱北京大学物理学院大气与海洋科学系气候与海—气实验室北京100871

基于对流层二氧化氮(NO_(2))垂直柱浓度卫星遥感数据,实现快速、高空间水平分辨率(5 km或更高)的氮氧化物(NO_(x)=NO+NO_(2))排放反演,可为空气污染精准治理提供及时、细致的排放数据。现有多种低计算成本的快速反演方法,如指数修正高... 详细信息

基于对流层二氧化氮(NO_(2))垂直柱浓度卫星遥感数据,实现快速、高空间水平分辨率(5 km或更高)的氮氧化物(NO_(x)=NO+NO_(2))排放反演,可为空气污染精准治理提供及时、细致的排放数据。现有多种低计算成本的快速反演方法,如指数修正高斯模型、散度模型和PHLET算法,但其反演效果尚未得到充分对比分析。以2019年夏季京津冀地区为研究对象,对比了上述3种方法的反演效果,研究发现,指数修正高斯模型主要适用于点源排放,但在京津冀等排放源密集地区的反演效果较差;散度模型考虑了在预定NO_(x)大气寿命情况下的水平输送,能快速识别主要排放源位置,但存在排放低估和负排放等问题;PHLET算法考虑了水平输送、NO_(2)垂直柱浓度和NO_(x)大气寿命的非线性关系以及卫星像元不规则等因素,对排放的估计较为准确。改善风场数据、填补卫星数据缺失和改善NO_(x)化学损失估计是进一步提升排放反演质量的关键。

关键词：卫星遥感氮氧化物排放快速反演京津冀

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