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石英玻璃的紫外飞秒激光光丝高精度加工技术研究

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中国激光 2024年第12期51卷 465-473页

作者：薛波贾平岗安国文苏建慧王灏荃杨楠熊继军中北大学省部共建动态测试技术国家重点实验室山西太原030051

石英玻璃的高精度加工在微机电器件封装、光纤传感和微电子封装等领域有着巨大的需求。为进一步提升加工精度和加工质量,本课题组开展了基于光丝效应的343 nm紫外飞秒激光加工实验,研究了激光焦点位置、脉冲能量、重复频率、扫描速度和... 详细信息

石英玻璃的高精度加工在微机电器件封装、光纤传感和微电子封装等领域有着巨大的需求。为进一步提升加工精度和加工质量,本课题组开展了基于光丝效应的343 nm紫外飞秒激光加工实验,研究了激光焦点位置、脉冲能量、重复频率、扫描速度和扫描次数对石英玻璃光丝损伤形貌的影响,并在此基础上优化工艺参数,对石英玻璃进行了快速切割和打孔实验。研究结果表明:在激光重复频率一定时,脉冲能量越大,光丝损伤越深;脉冲能量不变时,重复频率越高,光丝损伤深度越大;扫描速度的降低会增加损伤深度,但也会使加工表面的熔融物增多;增加扫描次数能显著提升加工质量。利用激光光丝加工方法切割得到的石英玻璃断面接近垂直且粗糙度小于1μm,微孔加工的尺寸精度可达到±2μm。

关键词：飞秒激光石英玻璃光丝效应精密切割微孔加工

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长白山苔原植物深色有隔内生真菌物种多样性

应用生态学报 2024年第6期35卷 1689-1694页

作者：苏丹孙蕊许榕凡张文浩吕国忠沈阳大学生命科学与工程学院沈阳110044 大连民族大学环境与资源学院辽宁大连116600

从长白山自然保护区苔原带典型植物牛皮杜鹃、毛毡杜鹃、笃斯越橘、仙女木的根系分离获得深色有隔内生真菌(DSE)菌株,研究其侵染定殖情况。采用形态特征与rDNA ITS序列分析相结合进行分类鉴定,研究了4种苔原植物的DSE真菌群落组成和物... 详细信息

从长白山自然保护区苔原带典型植物牛皮杜鹃、毛毡杜鹃、笃斯越橘、仙女木的根系分离获得深色有隔内生真菌(DSE)菌株,研究其侵染定殖情况。采用形态特征与rDNA ITS序列分析相结合进行分类鉴定,研究了4种苔原植物的DSE真菌群落组成和物种多样性。结果表明:4种苔原植物的根系内均形成DSE的典型结构“微菌核”。共分离出69株DSE菌株,分属于10个属12个种,分别是福廷瓶头霉、链格孢、细极链格孢、黑附球菌、小孢金丝酵母、白蜡树炭疽菌、茶树炭疽菌、小球腔菌属、枝状枝孢霉、茎点霉属、淡领瓶霉属、Discosia italica,具有丰富的物种多样性,且所有种均为我国高山苔原带首次报道的DSE真菌,其中福廷瓶头霉为各苔原植物的共有种和优势种。4种苔原植物DSE真菌的Simpson、Pielou和Shannon多样性指数均差异显著。表明苔原植物具有丰富的DSE真菌多样性,且二者能够形成良好的共生关系,增强苔原植物对环境的适应性。

关键词：深色有隔内生真菌侵染特征群落组成物种多样性

基于新型电力系统信息模型的重点区域高压输电线路损毁态势感知预警方法研究

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电测与仪表 2024年第6期61卷 133-140页

作者：齐立忠张苏武宏波高群策国网经济技术研究院有限公司北京100096

由于高压输电线路通常具有复杂的结构和特性,受到自然灾害、设备故障等影响,使得数据采集难度加大,且存在较多噪声,导致线路损毁态势感知预警结果不理想。为此,提出一种基于新型电力系统信息模型的重点区域高压输电线路损毁态势感知预... 详细信息

由于高压输电线路通常具有复杂的结构和特性,受到自然灾害、设备故障等影响,使得数据采集难度加大,且存在较多噪声,导致线路损毁态势感知预警结果不理想。为此,提出一种基于新型电力系统信息模型的重点区域高压输电线路损毁态势感知预警方法。文章采集重点区域高压输电线路数据,采用最大重叠离散小波变换(maximum overlapping discrete wavelet transform,MODWT)算法滤波处理重点区域高压输电线路数据。采用混合递阶遗传算法优化处理径向基函数(radial basis function,RBF)神经网络结构和参数,将经过滤波处理的重点区域高压输电线路数据作为RBF神经网络的输入,实现重点区域高压输电线路损毁态势感知。通过实验结果表明,所提方法获取的重点区域高压输电线路损毁态势感知预警结果更加符合实际情况,可以为重点区域高压输电线路稳定运行提供有力的支持。

关键词：新型电力系统信息模型重点区域高压输电线路损毁态势感知预警

Estimation of BDS pseudorange biases with high temporal resolution:feasibility,affecting factors,and necessity

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Satellite Navigation 2023年第3期4卷 14-34页

作者： Ke su Guoqiang Jiao Department of Space Information Space Engineering UniversityNo.1 Bayi RoadBeijing 101416China University of Chinese Academy of Sciences Beijing 100049China

A common practice adopted for the pseudorange bias estimation and calibration assumes that Global Navigation Satellite System satellite-dependent pseudorange biases vary gently over *** satellite pseudorange biases are routinely estimated and provided as the products with low temporal resolution,e.g.,hourly or daily,by the *** story sounds unquestionably perfect under the acquainted *** validate the inadequacy of the above hypothesis we herein present an approach to the estimate the BeiDou Navigation Satellite System(BDS)pseudorange biases with high temporal *** feasibility,affecting factors,and necessity are ***,the Geometry-Free function models are first constructed to retrieve the linear combination of the pseudorange biases;then the pseudorange Observable-specific Signal Bias(OSB)values with respect to baseline frequencies(e.g.,BDS C2I/C6I)are estimated along with the ionosphere modeling;subsequently,all multi-frequency pseudorange OSBs are determined by using the ionospheric information with constraint conditions;finally,the possible Differential Code Bias sets are attainable with the estimated pseudorange *** the observation data of four months when the estimated BDS pseudorange biases are stable,their reliability is demonstrated with the stability at the level of sub-nanosecond and the BeiDou-3 Navigation Satellite System(BDS-3)values more stable than that of BeiDou-2 Navigation Satellite System(BDS-2).The comparison between the estimated pseudorange biases and the Chinese Academy of Sciences products reveals that the accuracy of the estimated pseudorange biases is 0.2–0.4 ***,the large magnitude of the short-term pseudorange bias variation in the tens of nanoseconds for the BDS-2 and BDS-3 are found in years 2021 and 2022,which are affected by two types of the satellite flex power for the BDS-2 and BDS-3,*** stress that it’s necessary to estimate the BDS pseudorange biases w

关键词： Beidou navigation satellite system(BDS) Pseudorange observable-specific signal bias(OSB) Differential code bias(DCB) Geometry-free(GF)function model Satellite flex power

Biomarkers for predicting efficacy of chimeric antigen receptor T cell therapy and their detection methods

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iLABMED 2024年第1期2卷 14-26页

作者： Bo Zou Yanzhou Song Ning Li Zhongyi Fan Jie Li Yuanzheng Peng Wanshan Wei Yuzi Zhang Yinan su Xianmin Meng Hongzhou Lu Xingding Zhang Xiaohua Tan Qibin Liao Department of Oncology and Bio-Therapeutic Center Shenzhen Third People's HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhenChina Molecular Cancer Research Center School of MedicineShenzhen Campus of Sun Yat-Sen UniversitySun Yat-Sen UniversityShenzhenChina Department of Hepato-Biliary surgery Shenzhen Third People's HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhenChina Institute for Hepatology National Clinical Research Centre for Infectious DiseasesShenzhen Third People's HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhenChina Kidney Transplant Department(Liver Transplant Department) Transplant CenterNational Clinical Research Center for Infectious DiseaseShenzhen Third People's HospitalThe Second Affiliated HospitalSouthern University of Science and TechnologyShenzhenChina Institute of Translational Medicine First Affiliated Hospital of Shenzhen UniversityShenzhen Second People's HospitalShenzhenGuangdongChina BASIS International School HuizhouGuangdongChina Department of Pharmacy Shenzhen Third People's HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhenChina

Cancer immunotherapy has emerged as the fourth most prevalent approach to tumor treatment,alongside surgery,radiotherapy,and *** several decades of development,chimeric antigen receptor T(CAR-T)cell therapy,a promising branch of adoptive T-cell therapy,has demonstrated superior efficacy and safety in comparison to other cell therapies in the treatment of *** present,CAR-T cells are predominantly used to treat hematological malignancies,although their application in solid tumors is being readily *** numerous studies have examined the biomarkers associated with the safety of CAR-T cell therapy,few have evaluated predictors of CAR-T cell therapeutic ***,the primary objective of this review article was to provide a comprehensive overview of the factors predicting the efficacy of CAR-T cell therapy,with a particular focus on biomarkers and their detection methods.

关键词： biomarkers cancer immunotherapy CAR-T cell detection methods therapeutic efficacy

Transition of electrical conductivity in carbon nanotube/silver particle composite buckypapers

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Particuology 2014年第6期12卷 15-21页

作者： Fenghua su Menghe Miao School of Mechanical and Automotive Engineering South China University of Technology CSIRO Materials Science and Engineering P.O.Box 21BelmontVictoria 3216Australia

The electrical conductivity of carbon nanotube buckypapers can be dramatically increased by incorporation of silver particles contained in a commercial silver *** methods,co-dispersion during the production of buckypaper and surface coating on a preformed buckypaper,were used to prepare composite *** two types of composite buckypapers exhibited very different electrical conductivity *** composite buckypapers prepared by the surface coating method showed a distinct step transition in electrical conductivity at 3 vol%silver content,leading to a 15-fold improvement at 6%silver *** composite buckypapers prepared by the co-dispersion method showed a gradual change in electrical conductivity with increasing silver particle content,resulting in a five-fold improvement at12%silver *** and sectional morphologies of the two types of composite buckypapers were examined and related to their electrical conductivity profiles.

关键词： Carbon nanotubes Buckypaper Electrical conductivity

Is there a primitive reflex residue underlying Marcus Gunn Syndrome? Rat electrophysiology

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International Journal of Ophthalmology(English edition) 2020年第1期13卷 29-35页

作者： Ying Qiao Hou-cheng Liang Jing-Dong Zhang Pi-Fu Luo An-Le su Ting Zhang Hong-Na Zhu Xi’an First Hospital Key Clinic Ophthalmology LabShaanxi Province Eye Research InstituteXi’an 710002Shaanxi ProvinceChina Xi’an BRIGHT Eye Hospital 234 West Youyi RoadXi’an 710068Shaanxi ProvinceChina Department of Ophthalmology Affiliated HospitalXi’an Jiaotong UniversityXi’an 710002Shaanxi ProvinceChina Department of Pathology University of Iowa College of MedicineIowa CityIA 52242USA

AIM: To make an electrophysiological demonstration of a possible jaw muscle afferents-oculomotor neural pathway that was proposed by our previous works on rats, which substantiates an early "release hypothesis" on pathogenesis of human Marcus Gunn Syndrome(MGS). METHODS: Extracellular unit discharge recording was applied and both orthodromic and spontaneous unitary firing were recorded in the oculomotor nucleus(III), and the complex of pre-oculomotor interstitial nucleus of Cajal and Darkschewitsch nucleus(INC/DN), following electric stimulation of the ipsilateral masseter nerve(MN) in rats. REsuLTS: Extracellular orthodromic unit discharges, with latencies of 3.7±1.3 and 4.7±2.9 ms, were recorded unilaterally in the III, and the INC/DN neurons, respectively. Spontaneous unit discharges were also recorded mostly in the INC/DN and less frequently in the III. Train stimulation could prompt either facilitation or inhibition on those spontaneous unit discharges. The inhibition pattern of train stimulation on the spontaneous discharging was rather different in the III and INC/DN. A slow inhibitory pattern in which spontaneous firing rate decreased further and further following repeated train stimulation was observed in the III. While, some high spontaneous firing rate units, responding promptly to the train stimuli with a short-term inhibition and recovered quickly when stimuli are off, were recorded in the INC/DN. However, orthodromic unit discharge was not recorded in the III and INC/DN in a considerable number of experiment animals. CONCLUSION: A residual neuronal circuit might exist in mammals for the primitive jaw-eyelid reflex observed in amphibians, which might not be well-developed in all experimental mammals in current study. Nonetheless, this pathway can be still considered as a neuroanatomic substrate for development of MGS in some cases among all MGS with different kind of etiology.

关键词： masseter nerve single unit discharge oculomotor nucleus pre-oculomotor neurons interstitial nucleus of Cajal/Darkschewitsch nucleus Marcus Gunn Syndrome

双定子无刷双馈风力发电机无速度传感器超螺旋滑模直接功率控制

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太阳能学报 2024年第8期45卷 595-602页

作者：朱连成肖阳苏晓英金石陈晓红辽宁工业大学电气工程学院锦州121001 沈阳工业大学电气工程学院沈阳110870

结合新型背靠背笼障转子耦合内外双定子无刷双馈发电机,提出一种无速度传感器直接功率控制方法。将电机内、外同相功率绕组及内、外同相控制绕组各自串联连接,采用超螺旋滑模控制及SVPWM技术,以固定开关频率驱动控制绕组机侧变流器功率... 详细信息

结合新型背靠背笼障转子耦合内外双定子无刷双馈发电机,提出一种无速度传感器直接功率控制方法。将电机内、外同相功率绕组及内、外同相控制绕组各自串联连接,采用超螺旋滑模控制及SVPWM技术,以固定开关频率驱动控制绕组机侧变流器功率器件,以模型参考自适应系统和Popov超稳定性理论设计发电机速度观测器,取代易发生故障的传统机电式转速/位置传感器。通过12/8极50 kW样机控制系统的特性仿真,验证了所提无速度传感器超螺旋滑模直接功率控制策略的正确性和有效性。

关键词：海上风电风力机双定子无刷双馈发电机超螺旋滑模直接功率控制最大功率跟踪模型参考自适应系统

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高含硫天然气管道泄漏H_(2)S扩散规律研究

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成都理工大学学报（自然科学版） 2024年第1期51卷 130-136页

作者：苏诗漫王浩丞史春艳刘名名中国石油西南油气田分公司川东北气矿四川达州635000 成都理工大学能源学院成都610059

在高含硫天然气管道中,泄漏事故的风险较高,一旦事故发生,将对周围建筑和居民安全构成严重威胁。本研究聚焦于含5%硫化氢(H_(2)S)的天然气管道,利用计算流体力学方法对水平泄漏扩散进行了数值模拟。特别研究了风速对泄漏口上游建筑各楼... 详细信息

在高含硫天然气管道中,泄漏事故的风险较高,一旦事故发生,将对周围建筑和居民安全构成严重威胁。本研究聚焦于含5%硫化氢(H_(2)S)的天然气管道,利用计算流体力学方法对水平泄漏扩散进行了数值模拟。特别研究了风速对泄漏口上游建筑各楼层硫化氢体积分数的影响。主要发现包括:(1)通过在仿真的房屋模型中各楼层设置监测点,观察到随着楼层增高,H_(2)S气团扩散至房间的时间显著缩短。(2)随着风速的变化,位于高层(第11层至第24层)的房间内H_(2)S气团扩散时间随风速的增加而减少。而对于低层(第1层至第10层)的房间,在风速低于9 m/s时,H_(2)S气团扩散时间随风速增加而延长;但当风速超过9 m/s时,扩散时间随风速增加而缩短。这些结果为高含硫天然气管道泄漏事故的应急响应和安全管理提供了重要参考。

关键词：天然气管道数值模拟泄漏扩散硫化氢