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Mucinous neoplasm of the appendix:A case report and review of literature

World Journal of Gastrointestinal Surgery 2024年第3期16卷 944-954页

作者： hao-cheng chang Jung-cheng Kang Ta-Wei Pu Ruei-Yu Su Chao-Yang Chen Je-Ming Hu Department of Surgery Tri-Service General HospitalTaipei 114TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTaiwanChina Adventist HospitalTaipei 105TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTri-Service General Hospital Songshan BranchNational Defense Medical CenterTaipei 105TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 105TaiwanChina Department of Pathology and Laboratory Medicine Taoyuan Armed Forces General HospitalTaoyuan 325TaiwanChina

BACKGROUND Appendiceal mucinous neoplasms(AMNs),although not classified as rare,are relatively uncommon tumors most often discovered incidentally during colorectal *** identification of AMNs is difficult due to non-specific sym-ptoms,overlapping tumor markers with other conditions,and the potential for *** underscores the urgent need for precision in diagnosis to pre-vent severe *** SUMMARY This case report describes the unexpected discovery and treatment of a low-grade AMN(LAMN)in a 74-year-old man undergoing laparoscopic hemicolectomy for transverse colon adenocarcinoma(AC).Preoperatively,non-specific gastroin-testinal symptoms and elevated tumor markers masked the presence of *** tumor,presumed to be an AMN peritoneal cyst intraoperatively,was con-firmed as LAMN through histopathological *** neoplasm exhibited mucin accumulation and a distinct immunohistochemical profile:Positive for Ho-meobox protein CDX-2,Cytokeratin 20,special AT-rich sequence-binding protein 2,and Mucin 2 but negative for cytokeratin 7 and Paired box gene *** profile aids in distinguishing appendiceal and ovarian mucinous *** recovery was uncomplicated,and the patient initiated adjuvant chemotherapy for the colon *** This case highlights the diagnostic complexity of AMNs,emphasizing the need for vigilant identification to avert potential complications,such as pseudomyxoma peritonei.

关键词： Adenocarcinoma Appendiceal neoplasms Low-grade appendiceal mucinous neoplasm Peritoneal neoplasms Pseudomyxoma peritonei Case report

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The Minimum Centroid Branch Spanning Tree Problem

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Journal of the Operations Research Society of China 2024年第2期12卷 528-539页

作者： hao Lin cheng He School of Science Henan University of TechnologyZhengzhou450001HenanChina

For a spanning tree T of graph G,the centroid of T is a vertex v for which the largest component of T-v has as few vertices as *** number of vertices of this component is called the centroid branch weight of *** minimum centroid branch spanning tree problem is to find a spanning tree T of G such that the centroid branch weight is *** application to design of communication networks,the loads of all branches leading from the switch center should be as balanced as *** this paper,we prove that the problem is strongly NP-hard even for bipartite ***,the problem is shown to be polynomially solvable for split graphs,and exact formulae for special graph familis,say Kn_(1),n_(2),...,n_(k)and P_(m)×P_(n),are presented.

关键词： Spanning tree optimization Centroid branch-NP-hardness Polynomial-time algorithm

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Performance of double-arch tunnels under internal BLEVE

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Underground Space 2024年第6期19卷 6-25页

作者： Ruishan cheng Wensu Chen Hong hao Center for Infrastructural Monitoring and Protection School of Civil and Mechanical EngineeringCurtin UniversityPerth 6000Australia Earthquake Engineering Research&Test Center Guangzhou UniversityGuangzhou 510000China

Double-arch tunnels,as one of the popular forms of tunnels,might be exposed to boiling liquid expanding vapour explosions(BLEVEs)associated with transported liquified petroleum gas(LPG),which could cause damage to the tunnel and even catastrophic collapse of the tunnel in extreme ***,very limited study has investigated the performance of double-arch tunnels when exposed to internal BLEVEs and in most analyses of tunnel responses to accidental *** TNT-equivalence method was used to approximate the explosion load,which may lead to inaccurate tunnel response *** study numerically investigates the response of typical double-arch tunnels to an internal BLEVE resulting from the instantaneous rupture of a 20 m^(3) LPG *** of various factors,including in-situ stresses,BLEVE locations,and lining configurations on tunnel responses are *** results show that the double-arch tunnels at their early-operation ages are more vulnerable to severe damage when exposed to the BLEVE due to the low action of in-situ stress of rock mass on the response of early-age *** is also found that directing the LPG tank to different driving lanes inside tunnels can affect the BLEVE-induced tunnel response more significantly than varying the configurations of tunnel ***,installing section-steel arches in the mid-wall can effectively improve the blast resistance of the double-arch tunnels against the internal *** addition,the prediction models based on multi-variate nonlinear regressions and machine learning methods are developed to predict the BLEVE-induced damage levels of the double-arch tunnels without and with section-steel arches.

关键词： Double-arch tunnel BLEVE Lining configuration Section-steel arch Damage prediction

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Deep learning-based semantic segmentation of human features in bath scrubbing robots

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Biomimetic Intelligence & Robotics 2024年第1期4卷 70-79页

作者： Chao Zhuang Tianyi Ma Bokai Xuan cheng chang Baichuan An Minghuan Yin hao Sun School of Artificial Intelligence and Data Science Hebei University of TechnologyTianjin 300401China Engineering Research Center of Intelligent Rehabilitation Device and Detection Technology Ministry of EducationTianjin 300401China

With the rise in the aging population,an increase in the number of semidisabled elderly individuals has been noted,leading to notable challenges in medical and healthcare,exacerbated by a shortage of nursing *** study aims to enhance the human feature recognition capabilities of bath scrubbing robots operating in a water fog *** investigation focuses on semantic segmentation of human features using deep learning ***,3D point cloud data of human bodies with varying sizes are gathered through light detection and ranging to establish human ***,a hybrid filtering algorithm was employed to address the impact of the water fog environment on the modeling and extraction of human ***,the network is refined by integrating the spatial feature extraction module and the channel attention module based on *** results indicate that the algorithm adeptly identifies feature information for 3D human models of diverse body sizes,achieving an overall accuracy of 95.7%.This represents a 4.5%improvement compared with the PointNet network and a 2.5%enhancement over mean intersection over *** conclusion,this study substantially augments the human feature segmentation capabilities,facilitating effective collaboration with bath scrubbing robots for caregiving tasks,thereby possessing significant engineering application value.

关键词： 3D point cloud Human model LiDAR Semantic segmentation

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Atypical cervical spondylotic radiculopathy resulting in a hypertensive emergency during cervical extension: A case report and review of literature

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World Journal of Orthopedics 2024年第10期15卷 981-990页

作者： hao-cheng Cui Zheng-Qi chang Shao-Ke Zhao Department of Orthopedic Surgery 960th Hospital of PLAJinan 250031Shandong ProvinceChina

BACKGROUND Extensive research revealed the absence of reports documenting hypertensive emergencies precipitated by changes in the cervical spine *** SUMMARY We here present a 57-year-old woman diagnosed as having cervical spondylotic radiculopathy(CSR)who was scheduled for anterior cervical decompression and *** post-anesthetic positioning,a sudden hypertensive surge was observed when the patient was in a supine position with the neck being slightly *** surge was promptly reversed through cervical flexion and head *** event however required an alternate surgical approach for recovery—posterior laminoplasty and endoscopy-assisted nucleus pulposus *** the 6-month outpatient follow-up period,cervical flexion and extension activities substantially improved in the patient without any episodes of increase in acute blood *** Maintaining a safe hypotensive posture and performing rapid,thorough deco-mpression surgery may serve as effective interventions for patients presenting symptoms similar to those of CSR accompanied by hypertensive emergencies(HE).This would mitigate the underlying causes of these HEs.

关键词： Atypical cervical spondylotic radiculopathy Hypertensive emergency Supine position Endoscopic-assisted Case report

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Contrasting strategies of optimizing carrier concentration in bulk InSe for enhanced thermoelectric performance

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Rare Metals 2024年第9期43卷 4425-4432页

作者： hao-Nan Shi Shu-Lin Bai Yu-Ping Wang Li-Zhong Su Qian Cao cheng chang Li-Dong Zhao School of Materials Science and Engineering Beihang UniversityBeijing 100191China School of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024China Huabei Cooling Device Co.Ltd. Hebei 065400China

Indium selenide(InSe),as a wide-bandgap semiconductor,has received extensive attention in the flexible electronics field in recent years due to its exceptional plasticity and promising thermoelectric ***,the low carrier concentration severely limits its thermoelectric performance *** this work,we conducted contrasting strategies that can be employed to increase the carrier concentration of InSe,including bandgap narrowing and heterovalent ***,the carrier concentration initially increases as a result of the reduced bandgap upon Te alloying and then slightly decreases due to the weak electronegativity of *** Br doping realizes high carrier concentration by pushing the Fermi level into the conduction bands and activating the multiple *** the other hand,both Te and Br obviously suppress the thermal conductivity due to the point defect *** contrast,Br doping realizes a higher thermoelectric performance with a maximum ZT of~0.13 at 773 K benefiting from the better optimization of carrier *** work elucidates the strategies for enhancing carrier concentration at anion sites and demonstrates the high efficiency of halogen doping in ***,the carrier concentration of InSe is promising to be further optimized,and future work should focus on employing approaches such as cation doping or secondphase compositing.

关键词： Thermoelectric InSe Carrier concentration Bandgap Heterovalent doping

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MLDA:a multi-level k-degree anonymity scheme on directed social network graphs

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Frontiers of Computer Science 2024年第2期18卷 199-215页

作者： Yuanjing hao Long LI Liang chang Tianlong GU Guangxi Key Laboratory of Trusted Software Guilin University of Electronic TechnologyGuilin 541004China Engineering Research Center of Trustworthy AI(Ministry of Education) Jinan UniversityGuangzhou 510632China

With the emergence of network-centric data,social network graph publishing is conducive to data analysts to mine the value of social networks,analyze the social behavior of individuals or groups,implement personalized recommendations,and so ***,published social network graphs are often subject to re-identification attacks from adversaries,which results in the leakage of users’***-anonymity technology is widely used in the field of graph publishing,which is quite effective to resist re-identification ***,the current researches still exist some issues to be solved:the protection of directed graphs is less concerned than that of undirected graphs;the protection of graph structure is often ignored while achieving the protection of nodes’identities;the same protection is performed for different users,which doesn’t meet the different privacy requirements of ***,to address the above issues,a multi-level-degree anonymity(MLDA)scheme on directed social network graphs is proposed in this ***,node sets with different importance are divided by the firefly algorithm and constrained connectedness upper approximation,and they are performed different-degree anonymity protection to meet the different privacy requirements of ***,a new graph anonymity method is proposed,which achieves the addition and removal of edges with the help of fake *** addition,to improve the utility of the anonymized graph,a new edge cost criterion is proposed,which is used to select the most appropriate edge to be ***,to protect the community structure of the original graph as much as possible,fake nodes contained in a same community are merged prior to fake nodes contained in different *** results on real datasets show that the newly proposed MLDA scheme is effective to balance the privacy and utility of the anonymized graph.

关键词： directed social network graph graph publishing k-degree anonymity community structure graph utility

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Advanced nanofabrication for elastic inorganic aerogels

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Nano Research 2024年第10期17卷 8842-8862页

作者： Xiaota cheng Xinyi chang Fan Wu Yalong Liao Kai Pan hao Fong Jianyong Yu Yi-Tao Liu Bin Ding Innovation Center for Textile Science and Technology College of TextilesDonghua UniversityShanghai 201620China Aerospace Institute of Advanced Material and Processing Technology Beijing 100074China College of Materials Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China

Inorganic aerogels with low density,high porosity,large specific surface area,and superior mechanical properties are excellent candidate materials in fields such as thermal management,energy,catalysis,and biomedical applications.A comprehensive overview of existing elastic inorganic aerogels is provided,covering their structural units,preparation methods,mechanical performances,and ***,based on the constituent building blocks and microstructures,a detailed analysis of the mechanical properties and guidelines for elastic design of aerogels is *** with a succinct summary of prospective developmental direction,this review deliberates on the challenges and potential opportunities of elastic inorganic aerogels,with the intent of providing a versatile platform for designing new types of elastic inorganic aerogels for various applications.

关键词： inorganic aerogels compressive stretchable fabrication mechanical performances applications

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Effect of tubastatin A on NLRP3 inflammasome activation in macrophages under hypoxia/ reoxygenation conditions

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World Journal of Emergency Medicine 2024年第4期15卷 289-296页

作者： hao Li chang Liu Ying Cui Panpan chang Wei Chong Department of Emergency Medicine the First Hospital of China Medical UniversityShenyang 110001China Trauma Medicine Center Peking University People's HospitalBeijing 100871China Key Laboratory of Trauma and Neural Regeneration Peking UniversityBeijing 100871China National Center for Trauma Medicine of China Beijing 100871China

BACKGROUND:There are currently no effective drugs to mitigate the ischemia/reperfusion injury caused by fluid resuscitation after hemorrhagic shock(HS).The aim of this study was to explore the potential of the histone deacetylase 6(HDAC6)-specific inhibitor tubastatin A(TubA)to suppress nucleotide-binding oligomerization domain-like receptor protein 3(NLRP3)inflammasome activation in macrophages under hypoxia/reoxygenation(H/R)***:The viability of RAW264.7 cells subjected to H/R after treatment with different concentrations of TubA was assessed using a cell-counting kit-8(CCK8)***,2.5μmol/L TubA was used with RAW264.7 cells under H/R ***264.7 cells were divided into three groups,namely the control,H/R,and TubA *** levels of reactive oxygen species(ROS)in the cells were detected using fluorescence *** protein expression of HDAC6,heat shock protein 90(Hsp90),inducible nitric oxide synthase(iNOS),NLRP3,gasdermin-D(GSDMD),Caspase-1,GSDMD-N,and Caspase-1 p20 was detected by western *** levels of interleukin-1β(IL-1β)and IL-18 in the supernatants were detected using enzyme-linked immunosorbent assay(ELISA).RESULTS:HDAC6,Hsp90,and iNOS expression levels were significantly higher(P<0.01)in the H/R group than in the control group,but lower in the TubA group than in the H/R group(P<0.05).When comparing the H/R group to the control group,ROS levels were significantly higher(P<0.01),but significantly reduced in the TubA group(P<0.05).The H/R group had higher NLRP3,GSDMD,Caspase-1,GSDMD-N,and Caspase-1 p20 expression levels than the control group(P<0.05),however,the TubA group had significantly lower expression levels than the H/R group(P<0.05).IL-1βand IL-18 levels in the supernatants were significantly higher in the H/R group compared to the control group(P<0.01),but significantly lower in the TubA group compared to the H/R group(P<0.01).CONCLUSION:TubA inhibited the expression of HDAC6,Hsp90,and iNOS in macrophages

关键词： Hemorrhagic shock Hypoxia/reoxygenation Macrophage NLRP3 Tubastatin A

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Enhancement of mechanical and tribological performance of Ti-6Al-4V alloy by laser surface alloying with Inconel 625 and SiC precursor materials

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Friction 2024年第9期12卷 2089-2107页

作者： hao-Ran cheng Ki-Hoon SHIN Hong Seok KIM Department of Mechanical Engineering Graduate School of Seoul National University of Science and TechnologySeoul 01811Republic of Korea Department of Mechanical and Automotive Engineering Seoul National University of Science and TechnologySeoul 01811Republic of Korea

This study focused on producing metal matrix composite(MMC)coatings on Ti–6Al–4V alloy through laser surface alloying using a novel combination of Inconel 625 and SiC precursor *** ratios of alloying powders were examined to evaluate surface properties such as microhardness,wear resistance,and friction coefficient,along with analyzing the phase composition and microstructure of the *** in situ synthesized MMC coatings exhibited the presence ofα-Ti,NiTi,NiTi_(2),and TiC ***,Ti_(5)Si_(3)andα-Ti/Ti_(5)Si_(3)eutectic structures were observed when the SiC content exceeded 20%.In comparison to the titanium substrate,the MMC coating significantly enhanced microhardness by over threefold and reduced wear by 95%.However,it was crucial to carefully select the appropriate combination of alloying powders to avoid a substantial decrease in friction performance and excessive formation of *** a comparative analysis of experimental results,the optimal precursor material composition was identified as 85%Inconel 625 and 15%*** study demonstrated the effective utilization of Inconel 625 and SiC alloying materials to enhance the surface properties of titanium alloys,thereby expanding their application in challenging environments.

关键词： titanium alloy Inconel 625 SiC ceramic laser surface alloying metal matrix composite(MMC)

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