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Impact of minimally invasive surgery on immune function and stress response in gastric cancer patients

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2484-2493页

作者： rong-Hua Zhu Peng-cheng Li jie Zhang Hua-Hua Song Department of General Surgery Chongming Hospital Affiliated to Shanghai University of Medicine and Health SciencesShanghai 202150China Department of Respiratory Medicine Chongming Hospital Affiliated to Shanghai University of Medicine and Health ScienceShanghai 202150China

BACKGROUND Gastric cancer remains a leading cause of cancer-related mortality *** open surgery for gastric cancer is often associated with significant morbidity and prolonged *** To evaluate the effectiveness of laparoscopic minimally invasive surgery as an alternative to traditional open surgery for gastric cancer,focusing on its potential to reduce trauma,accelerate recovery,and achieve comparable oncological *** This study retrospectively analyzed 203 patients with gastric cancer who underwent surgery at the Shanghai Health Medical College Affiliated Chongming Hospital from January 2020 to December *** patients were divided into two groups:Minimally invasive surgery group(n=102),who underwent laparoscopic gastrectomy,and open surgery group(n=101),who underwent traditional open *** compared surgical indicators(surgical incision size,intraop-erative blood loss,surgical duration,and number of lymph nodes dissected),recovery parameters(time to first flatus,time to start eating,time to ambulation,and length of hospital stay),immune function(levels of IgA,IgG,and IgM),intestinal barrier function(levels of D-lactic acid and diamine oxidase),and stress response(levels of C-reactive protein,interleukin-6,and procalcitonin).RESULTS The minimally invasive surgery group demonstrated significantly better outcomes in terms of surgical indicators,including smaller incisions,less blood loss,shorter surgery time,and more lymph nodes dissected(P<0.05 for all).Recovery was also faster in the minimally invasive surgery group,with earlier return of bowel function,earlier initiation of diet,quicker mobilization,and shorter hospital stays(P<0.05 for all).Furthermore,patients in the minimally invasive surgery group had better preserved immune function,superior intestinal barrier function,and a less pronounced stress response postoperatively(P<0.05 for all).CONCLUSION Laparoscopic minimally invasive surgery for gastric cancer not on

关键词： Gastric cancer Laparoscopic surgery Minimally invasive surgery Immune function Intestinal barrier Stress response

Capillary Property of Entangled Porous Metallic Wire materials and Its Application in Fluid Buffers:Theoretical Analysis and Experimental Study

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Defence Technology（防务技术） 2024年第1期31卷 400-416页

作者： Yu Tang Yiwan Wu Hu cheng rong Liu Engineering Research Center for Metal Rubber School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou 350156China AECC Guizhou Liyang Aviation Power Co. LTDGuiyang 550014China College of Computer and Information Sciences Fujian Agriculture and Forestry UniversityFuzhou 350156China

Strong impact does serious harm to the military industries so it is necessary to choose reasonable cushioning material and design effective buffers to prevent the impact of *** on the capillary property entangled porous metallic wire materials(EPMWM),this paper designed a composite buffer which uses EPMWM and viscous fluid as cushioning materials under the low-speed impact of the recoil force device of weapon equipment(such as artillery,mortar,etc.).Combined with the capillary model,porosity,hydraulic diameter,maximum pore diameter and pore distribution were used to characterize the pore structure characteristics of *** calculation model of the damping force of the composite buffer was *** low-speed impact test of the composite buffer was *** parameters of the buffer under low-speed impact were identified according to the model,and the nonlinear model of damping force was *** test results show that the composite buffer with EPMWM and viscous fluid can absorb the impact energy from the recoil movement effectively,and provide a new method for the buffer design of weapon equipment(such as artillery,mortar,etc.).

关键词： Entangled porous metallic wire materials Capillary property Viscousfluid Low-speed impact Damping force

Digital light processing based multimaterial 3D printing:challenges,solutions and perspectives

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International Journal of Extreme Manufacturing 2024年第4期6卷 151-174页

作者： Jianxiang cheng Shouyi Yu rong Wang Qi Ge Shenzhen Key Laboratory of Soft Mechanics&Smart Manufacturing Southern University of Science and TechnologyShenzhen 518055People's Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People's Republic of China

Multimaterial(MM)3D printing shows great potential for application in metamaterials,flexible electronics,biomedical devices and robots,since it can seamlessly integrate distinctive materials into one printed *** numerous MM 3D printing technologies,digital light processing(DLP)MM 3D printing is compatible with a wide range of materials from hydrogels to ceramics,and can print MM 3D structures with high resolution,high complexity and fast *** paper introduces the fundamental mechanisms of DLP 3D printing,and reviews the recent advances of DLP MM 3D printing technologies with emphasis on material switching methods and material contamination *** also summarizes a number of typical examples of DLP MM 3D printing systems developed in the past decade,and introduces their system structures,working principles,material switching methods,residual resin removal methods,printing steps,as well as the representative structures and ***,we provide perspectives on the directions of the further development of DLP MM 3D printing technology.

关键词： multimaterial 3D printing digital lightprocessing multimaterial 3Dstructures

Resolution and contrast enhancement in optical subtraction microscopy with annular aperture

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Optoelectronics Letters 2019年第2期15卷 93-97页

作者： LI Zheng-ya WANG Xiang-hui FAN Fei cheng jie-rong CHANG Sheng-jiang Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Institute of Modern Optics Nankai University

A method for improving lateral resolution and reducing imaging distortion of optical subtraction microscopy is ***, an azimuthally polarized(AP) light is modulated by an annular ***, an image with higher lateral resolution is obtained by subtracting an image obtained by an annular AP beam from an image obtained by a radially polarized *** simulation results demonstrate that compared with the case without the annular aperture, negative side-lobes in the effective point spread function are effectively suppressed, and the imaging quality of subtraction microscopy is obviously enhanced.

关键词： PSF Resolution enhancement subtraction

Strengthening and control of second-phase particle precipitation in ferritic/austenitic/martensitic heat-resistant alloys:a review

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Journal of Iron and Steel Research International 2024年第1期31卷 3-23页

作者： Xue-cheng Peng Han-jie Guo Xin-fang Zhang Yi-wa Luo Ye Sun Jing Guo rong-guang Yang Xiao-dan Zheng School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing100083China Beijing Key Laboratory of Special Melting and Preparation of High-End Metal Materials University of Science and Technology Beijing(USTB)Beijing100083China Beijing Shougang Gitane New MATERIALS Co. Ltd.Beijing102206China

Heat-resistant alloys with excellent mechanical properties are widely used in various fields,and further improvement in their properties is essential to meet the requirements in new-generation advanced supercritical boilers,nuclear reactors,superheaters,and other new materials *** effectively enhance the comprehensive performance of heat-resistant alloys,second-phase particle strengthening has been widely studied,and in the face of different service envi-ronments of advanced heat-resistant steels,the selection of suitable second-phase particles is essential to maximize the performance of these *** this end,three major types of reinforcing phases in heat-resistant alloys such as carbides,rare earth oxides,and intermetallic compounds are summarized.A comparative analysis of the precipitation behavior of the reinforcing phases with different types as well as the risks and means of controlling their use in service,is *** parameters for the application of various types of second-phase particles in heat-resistant alloys are provided to support the design and preparation of new ultrahigh-performance heat-resistant alloys.

关键词： Heat-resistant alloy Second-phase particle Carbide Rare earth oxide Intermetallic compound Strengthening

Immune cell pair ratio captured by imaging mass cytometry has superior predictive value for prognosis of non-small cell lung cancer than cell fraction and density

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Cancer Communications 2024年第5期44卷 589-592页

作者： Jian-rong Li Chao cheng Institute for Clinical and Translational Research Baylor College of MedicineHoustonTexasUSA Section of Epidemiology and Population Sciences Department of MedicineBaylor College of MedicineHoustonTexasUSA Dan L Duncan Comprehensive Cancer Center Baylor College of MedicineHoustonTexasUSA

Infiltrating immune cells in the tumor microenvironment(TME)play critical roles in the initiation,progression,and metastasis of cancer[1].Previous studies have reported that the infiltration levels of various immune cell types are significantly associated with patient prognosis in different cancers[2,3].Specifically,in non-small cell lung cancer(NSCLC)the prognostic associations of major immune cell types have been investigated[4–6],however,some of the reported associations are inconsistent and remain debated[7].Limited by technical issues,most studies focused on a few immune cell lineages or relied on inferred immune cell levels from computational *** investigate the prognostic effects of all major immune cell types unbiasedly,more systematic high-quality immune cell profiling data with matched patient survival information are needed.

关键词： prognosis cancer lung

Mg-doped,carbon-coated,and prelithiated SiO_(x) as anode materials with improved initial Coulombic efficiency for lithium-ion batteries

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Carbon Energy 2024年第3期6卷 204-214页

作者： Bin Liu jie Liu cheng Zhong Wenbin Hu Key Laboratory of Advanced Ceramics and Machining Technology(Ministry of Education) School of Materials Science and EngineeringTianjin UniversityTianjinChina Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjinChina Joint School of National University of Singapore and Tianjin University TianjinChina International Campus of Tianjin University Binhai New CityFuzhouChina

Silicon suboxide(SiO_(x),x≈1)is promising in serving as an anode material for lithium-ion batteries with high capacity,but it has a low initial Coulombic efficiency(ICE)due to the irreversible formation of lithium silicates during the first *** this work,we modify SiO_(x) by solid-phase Mg doping reaction using low-cost Mg powder as a reducing *** show that Mg reduces SiO_(2) in SiO_(x) to Si and forms MgSiO_(3) or Mg_(2)SiO_(4).The MgSiO_(3) or Mg_(2)SiO_(4) are mainly distributed on the surface of SiO_(x),which suppresses the irreversible lithium-ion loss and enhances the ICE of SiO_(x).However,the formation of MgSiO_(3) or Mg_(2)SiO_(4) also sacrifices the capacity of SiO_(x).Therefore,by controlling the reaction process between Mg and SiO_(x),we can tune the phase composition,proportion,and morphology of the Mg-doped SiO_(x) and manipulate the *** obtain samples with a capacity of 1226 mAh g^(–1) and an ICE of 84.12%,which show significant improvement over carbon-coated SiO_(x) without Mg *** the synergistical modification of both Mg doping and prelithiation,the capacity of SiO_(x) is further increased to 1477 mAh g^(–1) with a minimal compromise in the ICE(83.77%).

关键词： initial Coulombic efficiency lithium-ion batteries magnesium doping prelithiation silicon suboxide

Cleaner production of 3.5 valent vanadium electrolyte from ammonium metavanadate by ammonia reduction-sulfuric acid dissolution method

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Tungsten 2024年第3期6卷 555-560页

作者： cheng Wang Lan-jie Li Hao Du College of Chemical Engineering University of Chinese Academy of Sciences Institute of Process Engineering National Engineering Research Center of Green Recycling for Strategic Metal Resources Chinese Academy of Sciences Hesteel Group Company Limited

The vanadium redox flow battery(VRFB) has been widely used in large-scale energy storage areas due to the advantages of long lifespan and high safety. However, the high preparation cost of vanadium electrolyte limits ... 详细信息

关键词： Ammonia

Electrochemical Mono-Deuterodefluorination of Trifluoromethyl Aromatic Compounds with Deuterium Oxide

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CCS Chemistry 2024年第1期6卷 230-240页

作者： jie Sheng Xu cheng Institute of Chemistry and Biomedical Sciences Jiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023 State Key Laboratory of Elemento-Organic Chemistry Nankai UniversityTianjin 30071

The deuterodifluoromethyl group CF_(2)D combines the structural features of CF_(3) and CD_(3) groups,finding wide applications in diverse pharmaceutical *** this work,the electrochemical monodeuterodefluorination of Ar-CF_(3) to Ar-CF_(2)D is achieved with an unreported deuterium atom transfer-coupled electron transfer pathway using D_(2)O as the only D source for the first time.A series of Ar-CF_(3) substances,including commercial pharmaceuticals,were converted to corresponding CF_(2)D products in up to 91% yield and 97% D-incorporation.A variety of functional groups,including pyridine,pyrrole,furan,thiophene,borate,thio ether,amine,amide,sulfonamide,and halide,are well tolerated in this protocol.t-BuOLi was an essential reagent to achieve chemoselective mono-defluorination.

关键词： electrochemistry C-F activation fluorinecontaining drugs deuterated drugs deuterium oxide