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Ablative behavior and mechanism of SiC_(f) /SiBCZr composites prepared by PIP process

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Journal of Advanced Ceramics 2024年第1期13卷 124-134页

作者： Mingwei chen Yuliang Zhao Haipeng qiu Shijian Liu Weijie Xie Yi chen Qiyue Zhang AVIC Manufacturing Technology Institute Beijing 100130China

SiC_(f)/SiBCZr composites were prepared by polymer precursor impregnation and pyrolysis process with near stoichiometric ratio SiC fiber preform as reinforcement phase and SiBCZr multiphase ceramic precursor as impregnating *** results highlighted that the SiC_(f)/SiBCZr composites exhibited excellent ablative properties after ablative tests at 1200℃/3600 s and 1400℃/3600 s,and the strength retention rates of the composites reached 90%and 85%,*** was mainly due to the liquid sealing effect of the ablative products represented by B2O_(3) and SiO_(2)∙B_(2)O_(3),which inhibited the ablative reaction by reducing the diffusion rate of the oxidation medium,and the solid pinning effect of the substances represented by SiO_(2),ZrO_(2),and ZrSiO_(4),which could play high viscosity and high strength characteristics to improve anti-erosion *** above-mentioned SiC_(f)/SiBCZr composites with corrosion resistance,oxidation resistance,and ablative resistance provided a solid material foundation and technical support for the development of reusable spacecraft hot-end components.

关键词： near stoichiometric ratio SiC fiber SiC_(f)/SiBCZr composite liquid sealing effect solid pinning effect

A Strong, Tough, and Self-Healing Strengthening Thioctic Acid-based Elastomer for Highly Reliable Flexible Strain Sensor

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Chinese Journal of Polymer Science 2024年第10期42卷 1610-1618页

作者： Xin-Yu chen Yu-Bing Fu Xue-Ling Yan lan Liu School of Materials Science and Engineering Key Lab of Guangdong Province for High Property and Functional Polymer Materials South China University ofTechnology

Elastomers with high strength and toughness, excellent self-healing properties, and biocompatibility have broad application prospects in wearable electronics and other fields, but preparing it remains a challenge. In this work, we propose a highly adaptable strategy by introducing the small molecule crosslinking agent of triethanolamine (TEA) to the poly(thioctic acid)(PTA) chains and preparing the PAx Ey elastomers using a simple synthesis step. This strategy stabilizes the PTA chains by constructing multiple non-covalent cross-linked dynamic networks, endowing materials with excellent strength and toughness (tensile strength of 288 kPa, toughness of 278.2 kJ/m3), admirable self-healing properties (self-healing efficiency of 121.6%within 7 h at 70°C), and good biocompatibility. The PAx Ey elastomers can also be combined with MWNTs to become flexible strain sensors, which can be used to monitor human joint movements with high sensitivity, repeatable responses, and stability.

关键词： Flexible strain sensor Ion clusters Multiple dynamic networks Self-healing strengthening Thioctic acid

Construction and properties of venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres

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Particuology 2024年第3期86卷 205-210页

作者： chenjing Liang Lingling Shi Zhengguo chen lan Zhou Zhaoxia Zhang Guoqing Zhang School of Materials Science and Engineering Zhejiang Sci-tech UniversityHangzhouChina College of Textile Science and Engineering Zhejiang Sci-tech UniversityHangzhouChina Zhejiang Provincial Innovation Center of Advanced Textile Technology ShaoxingChina

The aim of this work is to develop a venlafaxine hydrochloride sustained release system based on hollow mesoporous silica microspheres(HMSMs).HMSMs were innovatively prepared with tetraethyl silicate(TEOS)as the precursor and volatile n-heptane as a soft *** obtained HMSMs show a well-defined hollow structure with an average size of 967 nm and pore volume of 0.85 cm^(3)/g,implying it is a potential drug ***,venlafaxine hydrochloride(VF)was absorbed in the HMSMs with a content of 37.67% or *** sustained release effect is further measured by the dissolution in-strument at 37℃ and 50 rpm in ultrapure *** results showed that the HMSMs/VF system shows good sustained release properties compared with sustained release tablets with hydroxypropyl meth-ylcellulose as the main *** HMSMs sustained release system appears to be a promising candidate for a sustained drug release.

关键词： Hollowmesoporous silica microspheres(HMSMs) Venlafaxine hydrochloride Drug loading Sustained release

Efficient conversion of acoustic vortex using extremely anisotropic metasurface

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Frontiers of physics 2024年第4期19卷 257-264页

作者： Zhanlei Hao Haojie chen Yuhang Yin cheng-Wei qiu Shan Zhu Huanyang chen Institute of Electromagnetics and Acoustics and Department of Physics College of Physical Science and TechnologyXiamen UniversityXiamen 361005China Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3117583Singapore Department of Mechanical and Electrical Engineering Xiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China

Vortex wave and plane wave,as two most fundamental forms of wave propagation,are widely applied in various research ***,there is currently a lack of basic mechanism to enable arbitrary conversion between *** this paper,we propose a new paradigm of extremely anisotropic acoustic metasurface(AM)to achieve the efficient conversion from 2D vortex waves with arbitrary orbital angular momentum(OAM)to plane *** underlying physics of this conversion process is ensured by the symmetry shift of AM medium parameters and the directional compensation of ***,this novel phenomenon is further verified by analytical calculations,numerical demonstrations,and acoustic experiments,and the deflection angle and direction of the converted plane waves are qualitatively and quantitatively confirmed by a simple *** work provides new possibilities for arbitrary manipulation of acoustic vortex,and holds potential applications in acoustic communication and OAM-based devices.

关键词： efficient wave conversion vortex wave plane wave orbital angular momentum acoustic metasurface

Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2119-2136页

作者： Li Peng Yanyi Jiang Hengxing chen Yongqiang Wang qiusheng lan Shuiqin chen Zhanwang Huang Jingyuan Zhang Duanqing Tian Yuntan qiu Diankui Cai Jiangyun Peng Daning Lu Xiaoqing Yuan Xianzhu Yang Dong Yin Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Medical Research Center Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China Department of Gastrointestinal Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Department of Hepatobiliary Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China

Transcriptional dysregulation of genes is a hallmark of tumors and can serve as targets for cancer drug ***,it is extremely challenging to develop small-molecule inhibitors to target abnormally expressed transcription factors(TFs)except for the nuclear receptor family of *** is known about the interaction between TFs and transcription cofactors in gastroesophageal adenocarcinoma(GEA)or the therapeutic effects of targeting TF and transcription cofactor *** this study,we found that ETS homologous factor(EHF)expression is promoted by a core transcriptional regulatory circuitry(CRC),specifically ELF3-KLF5-GATA6,and interference with its expression suppressed the malignant biological behavior of GEA ***,we identified Ajuba LIM protein(AJUBA)as a new coactivator of EHF that cooperatively orchestrates transcriptional network activity in ***,we identified KRAS signaling as a common pathway downstream of EHF and ***,dual targeting of EHF and AJUBA by lipid nanoparticles cooperatively attenuated the malignant biological behaviors of GEA in vitro and in *** conclusion,EHF is upregulated by the CRC and promotes GEA malignancy by interacting with AJUBA through the KRAS *** of both EHF and its coactivator AJUBA through lipid nanoparticles is a novel potential therapeutic strategy.

关键词： EHF AJUBA KRAS pathway Enhancer Core transcriptional regulatory circuitry Gastroesophageal adenocarcinoma Gastric adenocarcinoma Esophageal adenocarcinoma Transcription factor Coactivator Lipid nanoparticles

Arbitrary acoustic orbital angular momentum detection using dual-layer metasurfaces

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 106-112页

作者： Zhanlei Hao Haojie chen Yuhang Yin Shan Zhu Yadong Xu cheng-Wei qiu Huanyang chen Department of Physics College of Physical Science and TechnologyXiamen UniversityXiamen 361005China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Department of Mechanical and Electrical Engineering Xiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China School of Physical Science and Technology and Jiangsu Key Laboratory of Thin Films Soochow UniversitySuzhou 215006China

Orbital angular momentum(OAM),with its unique physical properties and vast application prospects,has attracted widespread attention in various ***,the development of valid and practical acoustic OAM detection methods continues to be a challenging *** this paper,we propose a novel construction method of dual-layer metasurfaces to achieve a doubleconversion process for the waveform reshaping and differentiated focusing of two-dimensional vortex sources with different ***,by utilizing a concise formula,a one-to-one correspondence is established between the OAM of incident vortex waves and different imaging *** fundamental principle of this special conversion relationship is rigorously constrained by the directional compensation of phase and the material parameters of dual-layer metasurfaces with different quadratic phase *** importantly,the highly consistent results between numerical demonstrations and acoustic experiments further confirm the feasibility and effectiveness of the proposed OAM detection *** work provides a new perspective on the precise manipulation for the phase of vortex fields,holding potential applications in super-resolution imaging and the design of acoustic OAM-based devices.

关键词： arbitrary acoustic OAM detection vortex waves dual-layer metasurfaces waveform reshaping differentiated focusing acoustic experiments

An attention-based teacher-student model for multivariate short-term landslide displacement prediction incorporating weather forecast data

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Journal of Mountain Science 2024年第8期21卷 2739-2753页

作者： chen Jun HU Wang ZHANG Yu qiu Hongzhi WANG Renchao Sichuan Artificial Intelligence Research Institute Yibin 644000China School of Computer Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China School of Architecture and Civil Engineering Chengdu UniversityChengdu 610106China

Predicting the displacement of landslide is of utmost practical importance as the landslide can pose serious threats to both human life and ***,traditional methods have the limitation of random selection in sliding window selection and seldom incorporate weather forecast data for displacement prediction,while a single structural model cannot handle input sequences of different lengths at the same *** order to solve these limitations,in this study,a new approach is proposed that utilizes weather forecast data and incorporates the maximum information coefficient(MIC),long short-term memory network(LSTM),and attention mechanism to establish a teacher-student coupling model with parallel structure for short-term landslide displacement *** MIC,a suitable input sequence length is selected for the LSTM *** investigate the influence of rainfall on landslides during different seasons,a parallel teacher-student coupling model is developed that is able to learn sequential information from various time series of different *** teacher model learns sequence information from rainfall intensity time series while incorporating reliable short-term weather forecast data from platforms such as China Meteorological Administration(CMA)and Reliable Prognosis(https://***)to improve the model’s expression capability,and the student model learns sequence information from other time *** attention module is then designed to integrate different sequence information to derive a context vector,representing seasonal temporal attention ***,the predicted displacement is obtained through a linear *** proposed method demonstrates superior prediction accuracies,surpassing those of the support vector machine(SVM),LSTM,recurrent neural network(RNN),temporal convolutional network(TCN),and LSTM-Attention *** achieves a mean absolute error(MAE)of 0.072 mm,root mean square error(RMSE)of 0.096 mm,and pearson correlation coefficients(PC

关键词： landslide prediction MIC LSTM Attention mechanism Teacher Student model Prediction stability and interpretability

Accelerating BERT inference with GPU-efficient exit prediction

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Frontiers of Computer Science 2024年第3期18卷 31-42页

作者： Lei LI chengyu WANG Minghui qiu Cen chen Ming GAO Aoying ZHOU Shanghai Engineering Research Center of Big Data Management School of Data Science and EngineeringEast China Normal UniversityShanghai 200062China Alibaba Group Hangzhou 311121China KLATASDS-MOE School of StatisticsEast China Normal UniversityShanghai 200062China

BERT is a representative pre-trained language model that has drawn extensive attention for significant improvements in downstream Natural language Processing(NLP)*** complex architecture and massive parameters bring BERT competitive performance but also result in slow speed at model inference *** speed up BERT inference,FastBERT realizes adaptive inference with an acceptable drop in accuracy based on knowledge distillation and the early-exit ***,many factors may limit the performance of FastBERT,such as the teacher classifier that is not knowledgeable enough,the batch size shrinkage and the redundant computation of student *** overcome these limitations,we propose a new BERT inference method with GPU-Efficient Exit Prediction(GEEP).GEEP leverages the shared exit loss to simplify the training process of FastBERT from two steps into only one step and makes the teacher classifier more knowledgeable by feeding diverse Transformer outputs to the teacher *** addition,the exit layer prediction technique is proposed to utilize a GPU hash table to handle the token-level exit layer distribution and to sort test samples by predicted exit *** this way,GEEP can avoid batch size shrinkage and redundant computation of student *** results on twelve public English and Chinese NLP datasets prove the effectiveness of the proposed *** source codes of GEEP will be released to the public upon paper acceptance.

关键词： BERT FastBERT inference acceleration model distillation early exit text classification

First-principles study on the electronic structure of Pb_(10−x)Cu_(x)(PO_(4))_(6)O(x=0,1)

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Journal of Materials Science & Technology 2024年第4期171卷 66-70页

作者： Junwen Lai Jiangxu Li Peitao Liu Yan Sun Xing-qiu chen Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China

Recently,Lee et *** the experimental discovery of room-temperature ambient-pressure super-conductivity in a Cu-doped lead-apatite(LK-99)(arXiv:2307.12008,arXiv:2307.12037).Remarkably,the claimed superconductivity can persist up to 400 K at ambient *** the experimental im-plication,the electronic structure of LK-99 has not yet been ***,we investigate the electronic structures of LK-99 and its parent compound using first-principles calculations,aiming to elucidate the doping effects of *** results reveal that the parent compound Pb_(10)(PO_(4))_(6)O is an insulator,while Cu doping induces an insulator-metal transition and thus volume *** band structures of LK-99 around the Fermi level are featured by a half-filled flat band and a fully-occupied flat *** two very flat bands arise from both the 2p orbitals of 1/4-occupied O atoms and the hybridization of the 3d orbitals of Cu with the 2p orbitals of its nearest-neighboring O ***,we observe four van Hove singularities on these two flat ***,we show that the flat band structures can be tuned by including electronic correlation effects or by doping different *** find that among the considered doping elements(Ni,Cu,Zn,Ag,and Au),both Ni and Zn doping result in the gap opening,whereas Au exhibits doping effects more similar to Cu than *** work establishes a foundation for fu-ture studies to investigate the role of unique electronic structures of LK-99 in its claimed superconducting properties.

关键词： First-principles calculations Density functional theory Electronic structur e Superconductivity Flat bands Strongly correlated electrons