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Advances in ethnopharmacology,phytochemistry and pharmacology of Erigerontis Herba and its Chinese medicine prescriptions

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Traditional Medicine Research 2025年第1期10卷 44-61页

作者： Yang Zhou Yuan-Yan Huang Ding-Yue Shang Ying chen Meng Tian cheng-Yu Jin Xin lu Bing-Chun Yan Han-Qing Pang Institute of Translational Medicine School of MedicineYangzhou UniversityYangzhou 225009China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases Yangzhou UniversityYangzhou 225009China School of Medicine Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Guangxi Normal UniversityGuiling 541004China.

Erigerontis Herba(EH),the dried whole plant of Erigeron breviscapus,is well-known for circulating blood,activating meridians to alleviate pain,expelling wind,and clearing away *** has been extensively utilized in southern China for the treatment of stroke hemiplegia,chest stuffiness and pains,rheumatic arthralgia,headache,and *** review focuses on the botany,ethnopharmacology,phytochemistry,pharmacology and toxicity of EH and its related prescriptions to offer new insights for prospective research of *** information about EH was retrieved from ancient records and books,PubMed,China National Knowledge Infrastructure,Chinese Pharmacopoeia,Web of Science,Doctoral and Master’s Theses,and various electronic *** is a member of Compositae family and is mainly grown in southern *** Chinese medicine records that EH has the effects of circulating blood and removing blood stasis,expelling wind,and removing cold,as well as relieving rigidity of muscle and relieving *** now,nearly 200 ingredients have been characterized from EH,including flavonoids,caffeoyls,aromatic acids,coumarins,pentacyclic terpenoids,volatile oil and other *** extracts,EH related prescriptions(Dengzhan Xixin injection,Dengzhan Shengmai capsules,etc.)or compounds(scutellarin,scutellarein,etc.)possessed obvious therapeutic effects of ischemic stroke,cerebral hemorrhage,myocardial infarction,Alzheimer’s disease,diabetes and its complications,gastric cancer,bone,and joint degenerative ***,the major active compound of EH,has been used as a quality *** no obvious toxicity of EH has been *** to its traditional applications,ethnopharmacology,phytochemistry,pharmacology,and toxicity,EH was applied as a valuable herb for clinical application in food and medicine *** several compounds have been shown to possess diverse biological activities,the underlying mechanisms of their actions remain *** fully exploi

关键词： Erigeron breviscapus traditional applications ethnopharmacology phytochemistry pharmacology

Global Regularity for a 2D Model of Electro-Kinetic Fluid in a Bounded Domain

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Acta Mathematicae Applicatae Sinica 2018年第2期34卷 398-403页

作者： Miao-chao chen Sheng-qi lu Qi-lin LIU School of Applied Mathematics Chaohu University Anhui 238000 China Department of Mathematics and Physics Sanjiang University Jiangsu 210012 China School of Mathematics Southeast University Jiangsu 211189 China

In this paper, we consider an initial boundary value problem for a 2D model of electro-kinetic fluid in a smooth and bounded domain. We prove that the model has a unique global-in-time smooth solution.

关键词： euler equations electro-hydrodynamics global regularity

Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia

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Neural Regeneration Research 2025年第5期20卷 1397-1398页

作者： Zhenyu chen Xue-Jun Li Department of Biomedical Sciences University of Illinois College of Medicine RockfordRockfordILUSA Department of Bioengineering University of Illinois at ChicagoChicagoILUSA

Axonal degeneration underlies many debilitating diseases including hereditary spastic paraplegia(HSP),a genetically and clinically diverse group of disorders characterized by spasticity and weakness of the lower *** is one significant cause of chronic neurodisability due to the lack of effective treatments and a wide range of onset ages from early childhood to 70 years.

关键词： degeneration diseases hereditary

Turning in a Bipedal Robot

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Journal of Bionic Engineering 2013年第3期10卷 292-304页

作者： Jau-Ching lu Jing-Yi chen Pei-Chun lin Department of Mechanical Engineering National Taiwan University Taipei 106 Taiwan

We report the development of turning behavior on a child-size bipedal robot that addresses two common scenarios： turning in place and simultaneous walking and turning. About turning in place, three strategies are investigated and compared, including body-first, leg-first, and body/leg-simultaneous, These three strategies are used for three actions, respectively： when walking follows turning immediately, when space behind the robot is very tight, and when a large turning angle is desired. Concerning simultaneous walking and turning, the linear inverted pendulum is used as the motion model in the single-leg support phase, and the polynomial-based trajectory is used as the motion model in the double-leg support phase and for smooth motion connectivity to motions in a priori and a posteriori single-leg support phases. Compared to the trajectory generation of ordinary walking, that of simultaneous walking and turning introduces only two extra parameters： one for determining new heading direction and the other for smoothing the Center of Mass （COM） trajectory. The trajectory design methodology is validated in both simulation and experimental environments, and successful robot behavior confirms the effectiveness of the strategy.

关键词： turning biped humanoid trajectory planning robot

抗菌药降阶梯方案对老年重症获得性下呼吸道感染的临床疗效分析

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中国医学前沿杂志（电子版） 2018年第6期10卷 169-172页

作者：黄迪佳包永健陈林陆怡安广西壮族自治区江滨医院呼吸内科南宁530021

目的观察抗菌药降阶梯方案对老年重症获得性下呼吸道感染的临床疗效。方法选取2016年1月至2018年1月于本院就诊的老年重症获得性下呼吸道感染患者62例为研究对象,按照完全随机的方式分将其为观察组(31例)和对照组(31例),对照组患者进行... 详细信息

目的观察抗菌药降阶梯方案对老年重症获得性下呼吸道感染的临床疗效。方法选取2016年1月至2018年1月于本院就诊的老年重症获得性下呼吸道感染患者62例为研究对象,按照完全随机的方式分将其为观察组(31例)和对照组(31例),对照组患者进行常规抗感染治疗,观察组患者采用降阶梯方案进行抗感染治疗。比较两组患者的临床疗效、呼吸力学指标及炎性因子水平变化情况。结果观察组患者治疗总有效率显著高于对照组(P<0.05),感染控制时间和入住ICU时间均显著短于对照组(P_均<0.01),死亡率显著低于对照组(P<0.05)。治疗后,观察组患者吸气峰压(peak inspiratory pressure,PIP)、动态顺应性(dynamic compliance,Cdyn)、吸气阻力(airway resistance,Raw)均显著高于对照组(P_均<0.01),血清脑钠肽、C反应蛋白、白介素-6、降钙素原水平均显著低于对照组(P_均<0.01)。结论抗菌药降阶梯方案对老年重症获得性下呼吸道感染患者的疗效较好,可以明显改善患者肺功能,降低炎性因子水平。

关键词：抗菌药降阶梯方案老年重症获得性下呼吸道感染

Approximate Analytical Solutions for Scattering States of D-dimensional Hulthen Potentials

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Communications in Theoretical Physics 2011年第3期55卷 399-404页

作者： chen Chang-Yuan SUN Dong-Sheng LIU cheng-lin lu Fa-lin School of Physics and Electronics Yancheng Teachers University Yancheng 224002 China

Using the exponential function transformation approach along with an approximation for the centrifugal potential, the radial Schr6dinger equation of D-dimensional Hulthen potential is transformed to a hypergeometric differential equation. The approximate analytical solutions of scattering states are attained. The normalized wave functions expressed in terms of hypergeometrie functions of scattering states on the ＂k/2π scale＂ and the calculation formula of phase shifts are given. The physical meaning of the approximate analytical solutions is discussed.

关键词： D-dimensional Hulthen potential Schrodinger equation scattering states approximate analytical solutions

Autophagy-targeting modulation to promote peripheral nerve regeneration

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Neural Regeneration Research 2025年第7期20卷 1864-1882页

作者： Yan chen Hongxia Deng Nannan Zhang Department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityChengduSichuan ProvinceChina Key Laboratory of Birth Defects and Women and Children’s Diseases Ministry of EducationSichuan UniversityChengduSichuan ProvinceChina Laboratory of Reproductive Endocrinology and Reproductive Regulation Sichuan UniversityChengduSichuan ProvinceChina National Center for Birth Defect Monitoring West China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina

Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular *** studies have focused on factors that stimulate axonal outgrowth and myelin ***,recent studies have highlighted the pivotal role of autophagy in peripheral nerve regeneration,particularly in the context of traumatic ***,autophagy-targeting modulation has emerged as a promising therapeutic approach to enhancing peripheral nerve *** current understanding suggests that activating autophagy facilitates the rapid clearance of damaged axons and myelin sheaths,thereby enhancing neuronal survival and mitigating injury-induced oxidative stress and *** actions collectively contribute to creating a favorable microenvironment for structural and functional nerve regeneration.A range of autophagyinducing drugs and interventions have demonstrated beneficial effects in alleviating peripheral neuropathy and promoting nerve regeneration in preclinical models of traumatic peripheral nerve *** review delves into the regulation of autophagy in cell types involved in peripheral nerve regeneration,summarizing the potential drugs and interventions that can be harnessed to promote this *** hope that our review will offer novel insights and perspectives on the exploitation of autophagy pathways in the treatment of peripheral nerve injuries and neuropathies.

关键词： autophagy autophagy related genes Charcot–Marie–Tooth diseases diabetic peripheral neuropathy metformin myelination peripheral nerve injury Schwann cells sciatic nerve Wallerian degeneration

Preparation of porous titanium materials by powder sintering process and use of space holder technique

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Journal of Iron and Steel Research International 2017年第1期24卷 97-102页

作者： Xin-sheng Wang Zhen-lin lu Lei Jia Jiang-xian chen School of Materials Science and Engineering Xi'an University of TechnologyXi'an 710048ShaanxiChina

It is shown that an adapted powder sintering process can successfully prepare a 24.0%-35.5% porous titanium composite using 20μm Ti powder and rice husk particles ranging in size between 250μm and600μ*** phase constituents of the porous Ti composite samples were determined by X-ray diffraction（XRD）pattern sintered at 1250℃.The generation of silicon in the form of a TiSi2 solid solution,injected into the substrate,illustrates the solid solution strengthening *** average grain size of the tested sample and the grain boundary area increase along with the silicon *** indicates that silicon is dispersed within the green compact of *** the distance from a hole becomes greater,the nanohardness increases until it reaches a maximum hardness of 3.5GPa at approximately *** may be due to the solid solution strengthening of ***,nanohardness is 3.3GPa at a distance of approximately 0.5mm from a hole′s *** compressive strength is measured to be in the range of 440-938 *** strain reaches 14.8%-16.6% under compression testing.A large number of cleavage steps appear following a *** observed fracture is a brittle *** Ti composites with about 36% porosity have promising potential biomaterial applications,specifically related to bone implants and biological bearings.

关键词： Rice husk Porous Ti Sintering Porosity Hardness Mechanical property

Light-Weight Selective Image Encryption for Privacy Preservation

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Journal of Electronic Science and Technology 2020年第3期18卷 234-240页

作者： Yi-Hui chen Eric Jui-lin lu Chu-Fan Wang Department of Information Management Chang Gung UniversityTaichung 333323 Kawasaki Disease Center Kaohsiung Chang Gung Memorial HospitalKaohsiung 83301 Department of Management Information Systems National Chung Hsing UniversityTaichung 40227 Trend Micro Taipei 106

To protect personal privacy and confidential preservation,access control is used to authorize legal users for safe browsing the authorized contents on *** access control generates an authorization rule according to each permission ***,the general access control is inappropriate to apply in some social services(e.g.,photos posted on Flickr and Instagram,personal image management in mobile phone) because of the increasing popularity of digital images being stored and *** low maintenance loads,this paper integrates the data hiding technique to propose an access control mechanism for privacy *** proposed scheme changes the partial regions of a given image as random pads (called selective image encryption) and only allows the authorized people to remedy the random pads back to meaningful ones which are with similar visual qualities of original ones.

关键词： Fine-grained access control model image access control noise pads privacy protection