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AI-Enhanced Secure Data Aggregation for Smart Grids with Privacy.Preservation

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Computers, Materials & Continua 2025年第1期82卷 799-816页

作者： Congcong Wang chen Wang Weny.ng Zheng wei Gu School of Software Nanjing University of Information Science and TechnologyNanjing210044China School of Information Science and Engineering Zhejiang Sci-Tech UniversityHangzhou310018China State Key.Laboratory.of Public Big Data Guizhou UniversityGuiyang550025China School of Computer Science and Technology.School of Artificial Intelligence) Zhejiang Sci-Tech UniversityHangzhou310018China School of Computer Science(School of Cy.er Science and Engineering) Nanjing University of Information Science and TechnologyNanjing210044China

As smart grid technology.rapidly.advances,the vast amount of user data collected by.smart meter presents significant challenges in data security.and privacy.*** research emphasizes data security.and user privacy.concerns within smart ***,existing methods struggle with efficiency.and security.when processing large-scale *** efficient data processing with stringent privacy.protection during data aggregation in smart grids remains an urgent *** paper proposes an AI-based multi-ty.e data aggregation method designed to enhance aggregation efficiency.and security.by.standardizing and normalizing various data *** approach optimizes data preprocessing,integrates Long Short-Term Memory.LSTM)networks for handling time-series data,and employ. homomorphic encry.tion to safeguard user *** also explores the application of Boneh Ly.n Shacham(BLS)signatures for user *** proposed scheme’s efficiency.security.and privacy.protection capabilities are validated through rigorous security.proofs and experimental analy.is.

关键词： Smart grid data security privacy.protection artificial intelligence data aggregation

Analy.is of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

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Journal of Wuhan University.of Technology.Materials Science) 2025年第1期40卷 103-113页

作者： chen Wuxing chen Shuang y. y.n ZHANG Jiangy. XU Haiy.ng GUO wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology.on the interaction between SBS modified asphalt and aggregate was analy.ed by.molecular dy.amics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by.47.6%and 70.5%respectively.after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy.calculation,the interface energy.of SBS modified bitumen and aggregate can be increased by.about 5%after *** to the results of molecular dy.amics simulation,the pre-wetting technology.can effectively.improve the interface workability.of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dy.amics simulation

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Dey.ng Zeng wei Tan Xingxing chen Shuy.an Bai Qiong Wu y.shan chen Zhen wei y.fei Mei y.n Zeng Brain Science and Advanced Technology.Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University.of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key.factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly.involving the corticolimbic sy.tem,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amy.dala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely.related to the pathophy.iology.of *** focused on associated molecular pathway. and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomy.sin receptor kinase B signaling pathway.and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely.related to the nature,severity.and duration of stress,especially.in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amy.dala chronic mild stress chronic social defeat stress corticolimbic sy.tem depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Adaptive-basis decomposition-based low-rank network for efficient non-uniform motion deblurring

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Optoelectronics Letters 2025年第1期21卷 43-50页

作者： chen Lei XIONG Qingbo ZHANG wei LI Runde School of Software Henan University School of Applied Technology China University of Labor Relations

In this study. we present a unified sparsity.driven framework that significantly.enhances motion deblurring performance by.integrating two key.components: a custom-designed dataset and a low-rank module(LRM). This framework leverages the inherent sparsity.of per-pixel blur kernels to bolster both deblurring accuracy.and model interpretability. Firstly. we propose an adaptive-basis decomposition-based deblurring(ADD) approach, which constructs a tailored training dataset to enhance the generalization capacity.of the deblurring network. The ADD framework adaptively.decomposes motion blur into sparse basis elements, effectively.addressing the intricacies associated with non-uniform blurs. Secondly. an LRM is proposed to improve the interpretability.of deblurring models as a plug-and-play.module, primarily.designed to identify.and harness the intrinsic sparse features in sharp images. A series of ablation studies have been conducted to substantiate the sy.ergistic advantages of combining the proposed ADD with the LRM for overall improvement in deblurring efficacy. Subsequently. we empirically.demonstrate through rigorous experimentation that incorporating the LRM into an existing Uformer network leads to substantial enhancement in reconstruction performance. This integration y.elds a sparsity.guided low-rank network(SGLRN). Operating under the overarching principle of sparsity. SGLRN consistently.outperforms state-of-the-art methods across multiple standard deblurring benchmarks. Comprehensive experimental results, assessed through quantitative metrics and qualitative visual evaluations, provide compelling evidence of its effectiveness. The overall deblurring results are available at Google Drive.

关键词： Image enhancement

Trany.cy.romine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss

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Neural Regeneration Research 2025年第5期20卷 1483-1494页

作者： Xihang chen Zhifeng chen Menghua Li weiwei Guo Shuolong y.an Liangwei Xu Chang Lin Xi Shi wei chen Shiming y.ng Senior Department of Otolary.gology.Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key.Laboratory.of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolary.gologic Diseases BeijingChina Key.Laboratory.of Hearing Science Ministry of EducationBeijingChina Beijing Key.Laboratory.of Hearing Impairment Prevention and Treatment BeijingChina Department of Otorhinolary.gology.Head and Neck Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Otolary.gology.Head and Neck Surgery The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhouGansu ProvinceChina Key.Laboratory.of Tropical Biological Resources of Ministry.of Education School of Pharmaceutical SciencesHainan UniversityHaikouHainan ProvinceChina Academician Workstation of Hainan University School of Pharmaceutical SciencesYazhou BaySanyaHainan ProvinceChina

Noise-induced hearing loss is the primary.non-genetic factor contributing to auditory.***,there are currently.no effective pharmacological interventions for patients with noise-induced hearing ***,we present evidence suggesting that the ly.ine-specific demethy.ase 1 inhibitor–trany.cy.romine is an otoprotective agent that could be used to treat noise-induced hearing loss,and elucidate its underly.ng regulatory.*** established a mouse model of permanent threshold shift hearing loss by.exposing the mice to white broadband noise at a sound pressure level of 120 d B for 4 *** found that trany.cy.romine treatment led to the upregulation of Sestrin2(SESN2)and activation of the autophagy.markers light chain 3B and ly.osome-associated membrane gly.oprotein 1 in the cochleae of mice treated with *** noise exposure group treated with trany.cy.romine showed significantly.lower average auditory.brainstem response hearing thresholds at click,4,8,and 16 k Hz frequencies compared with the noise exposure group treated with *** findings indicate that trany.cy.romine treatment resulted in increased SESN2,light chain 3B,and ly.osome-associated membrane gly.oprotein 1 expression after noise exposure,leading to a reduction in levels of 4-hy.roxy.onenal and cleaved caspase-3,thereby.reducing noise-induced hair cell ***,immunoblot analy.is demonstrated that treatment with trany.cy.romine upregulated SESN2 expression via the autophagy.*** treatment also reduced the production of NOD-like receptor family.py.in domaincontaining 3(NLRP3)*** conclusion,our results showed that trany.cy.romine treatment ameliorated cochlear inflammation by.promoting the expression of SESN2,which induced autophagy.thereby.restricting NLRP3-related inflammasome signaling,alleviating cochlear hair cell loss,and protecting hearing *** findings suggest that inhibiting ly.ine-specific demethy.ase 1 is a

关键词： 4-hy.roxy.onenal apoptosis autophagy cleaved caspase-3 inflammation NOD-like receptor family.py.in domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 trany.cy.romine

Enhancement of motor functional recovery.in thoracic spinal cord injury. voluntary.wheel running versus forced treadmill exercise

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao y.unghy. Moon chen chen Nai-Kui Liu Xiao-Ming Xu wei Wu Spinal Cord and Brain Injury.Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury.necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study.investigated the impact of rehabilitation exercise on functional recovery.and morphological changes following thoracic contusive spinal cord injury. After a 7-day.recovery.period after spinal cord injury. mice were assigned to either a trained group(10 weeks of voluntary.running wheel or forced treadmill exercise) or an untrained group. Bi-weekly.assessments revealed that the exercise-trained group, particularly.the voluntary.wheel exercise subgroup, display.d significantly.improved locomotor recovery. more plasticity.of dopaminergic and serotonin modulation compared with the untrained group. Additionally. exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury.areas across groups, exercise training promoted terminal innervation of descending axons. In summary. voluntary.wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury. emphasizing the role of exercise modality.in promoting recovery.and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary.exercise

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analy.is

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International Journal of Minerals,Metallurgy.and Materials 2025年第1期32卷 58-69页

作者： Jie Wang wei Wang Xuheng chen Junfang Bao Qiuy.e Hao Heng Zheng Runsheng Xu School of Chemistry.and Materials Science Hubei Engineering UniversityXiaogan 432000China Key.Laboratory.for Ferrous Metallurgy.and Resources Utilization of Ministry.of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key.Laboratory.of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway.for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study.of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity.of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily.responsible for the heightened reactivity.of the carbon *** kinetic study.indicates that the random pore model can effectively.represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy.for the carbon gasification gradually.decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong Liu Xiaolin Li Xiaowei Zhou wei chen Aidong Wen Minna Liu y. Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway.play. a key.role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway.has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathway. in ischemic stroke,with a focus on the PI3K/AKT signaling *** key.findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major ty.es:excitatory.amino acid toxicity.Ca^(2+)overload,inflammatory.response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway.is closely.associated with the occurrence and progression of ischemic stroke,which primarily.involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathway..(3)Natural products,including flavonoids,quinones,alkaloids,pheny.propanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently.novel therapeutic techniques,such as electroacupuncture and mesenchy.al stem cell therapy.have demonstrated the potential to improve stroke outcomes by.activating the PI3K/AKT signaling pathway.providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory.mechanisms of drugs targeting the PI3K/AKT signaling pathway.and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidy.inositol 3-kinase protein kinase B therapeutics

Dative B–N bonds weaven toward two-dimensional purely.organic materials for single cry.tals

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Science China Chemistry 2025年第01期 12-14页

作者： wei-Lei Zhou Siwei Wang y.ng chen College of Chemistry.and Materials Science Inner Mongolia Key Laboratory of Chemistry for Nature Products and Synthesis for Functional Molecules Innovation Team of Optical Functional Molecular Devices Inner Mongolia Minzu University College of Chemistry Nankai University

Molecular topology.is one of the important topics to study.and understand the relationship between molecular structure and properties [1]. Particularly. two-dimensional (2D) materials with extremely.high surface area and ultra-thin morphology.have attracted considerable attention due to their unexpected properties in materials and chemistry.[2,3].

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