检索结果-南通市图书馆

中国激光 2001年第7期28卷 669-672页

作者：郑蔚黄志伟谢树森 S.M.Krishnan chia Teck chee 福建师范大学激光研究所福州350007 BiomedicalEngineeringResearchCenter SchoolofScience

采用新型显微荧光分光光度系统 ,实现激光诱导人肺组织内源性显微荧光光谱与图像的测量 ,获得不同组织层 (即上皮层 ,粘膜层和软骨层 )的荧光分布和荧光特性 ,为探索癌与正常组织自体荧光光谱特征差异的根源。

关键词：显微荧光分光光度系统内源性显微荧光光谱人肺组织激光疗法

What happened in 133 consecutive hepatic artery reconstruction in liver transplantation in 1 year?

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Hepatobiliary Surgery and Nutrition 2019年第1期8卷 10-18页

作者： Tsan-Shiun Lin Nelamangala Ramakrishnaiah Vishnu Prasad Chao-Long Chen Johnson chia-Shen Yang Yuan-Cheng chiang Pao-Jen Kuo Chih-Chi Wang Shih-Ho Wang Yueh-Wei Liu chee-Chien Yong Yu-Fan Cheng Liver Transplantation Program and Departments of Surgery and Diagnostic RadiologyKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiungTaiwan

Background:The immediate challenges during microvascular reconstruction of hepatic artery(HAR)during liver transplantation(LT)can be ***,in order to give a cross sectional view of these problems this study over a period of 1 year,showing our routine practice,was taken ***:From January 2015 to December 2015,a total of 133 LTs were performed in Kaohsiung Chang Gung Memorial Hospital,*** hepatic artery(HA)reconstructions were performed by a microvascular surgeon under an operating ***:In the 133 patients,one artery was anastomosed in 123(92.5%)patients,two in 9(6.8%)patients and three in 1(0.7%)of the ***(8.3%)arteries were less than 2 mm in size(1–1.9 mm).There were intimal dissections(IDs)involving either the donor or the recipient arteries of mild to severe nature in 9(6.8%)*** following graft arterial anastomosis,either there was no flow or an intraoperative hepatic artery thrombosis(HAT)was found in nine(7.1%—8 LDLT,4.8%—1 DDLT)*** re-do anastomosis was done in all of these patients who did well in the *** overall post-operative success rate was 99.2%.One patient(0.8%)developed postoperative HAT due to infection during follow up and died due to ***:Small vessels or HA injury are the frequently encountered problems by a micro vascular *** other problems could be ID,need to do multiple reconstructions,immediate HAT and ability to re-do the HAR immediately.

关键词： Hepatic artery(HA) thrombosis liver transplantation(LT) microvascular surgery reconstruction

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紫激光辐射人肺组织的光学特性

光学学报 2000年第2期20卷 229-233页

作者：谢树森郑蔚李步洪林棋榕黄志伟 chiaTeck-chee 福建师范大学激光研究所福州350007 新加坡南洋理工大学理学院

应用光纤探测系统和自行研制的光纤探针深度计,成功实现了Kr+紫激光辐射新鲜离体人肺组织体表面漫反射率和内部光能流率分布的精确测定,并利用漫射理论和加倍(AddingDoubling)方法的部分结论,获得了紫光人肺癌组织和正常组织的主要光学... 详细信息

应用光纤探测系统和自行研制的光纤探针深度计,成功实现了Kr+紫激光辐射新鲜离体人肺组织体表面漫反射率和内部光能流率分布的精确测定,并利用漫射理论和加倍(AddingDoubling)方法的部分结论,获得了紫光人肺癌组织和正常组织的主要光学特性参数,与蒙特卡罗法拟合实验的光分布曲线得出的结果一致。为临床实际应用提供了重要的原始参数。

关键词：光学特性人肺组织紫激光蒙特卡罗模拟肺癌

Development of annulus fibrosus tissue construct with hydrogel coils containing pre-conditioned mesenchymal stem cell

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Journal of Materials Science & Technology 2021年第4期63卷 27-34页

作者： Yon Jin Chuah Yingnan Wu Mei Ling Shirlynn Cheong Yan Qing chia Ching Ann Tee Hwan Tak Hee Chenjie Xu Yuejun Kang Dong-An Wang School of Chemical and Biomedical Engineering Nanyang Technological University62 Nanyang Drive637459Singapore Lee Kong chian School of Medicine Nanyang Technological University59 Nanyang Drive636921Singapore Pinnacle Spine&Scoliosis Centre 3 Mount ElizabethMount Elizabeth Medical Centre228510Singapore Faculty of Materials and Energy Institute for Clean Energy and Advanced MaterialsSouthwest UniversityChongqing 400715China Department of Biomedical Engineering City University of Hong Kong83 Tat Chee AvenueKowloonHong KongChina National Dental Centre of Singapore 5 Second Hospital Ave168938Singapore

Low back pain associated with degenerative disc diseases has been a major health concern that brings suffering to the patients physically and *** existing therapeutic strategies provide shortterm relief of symptoms rather than treatment of the underlying *** of an engineered tissue for disc regeneration is still in its infancy due to the limited autologous healthy disc cell source from the *** is also challenging to mimic the complexity of micro-architecture in the native disc tissue that determine their unique structural *** date,simple tissue models that mimic the annulus fibrosus(AF)micro-environment for understanding the potential of mesenchymal stem cells(MSCs)in AF tissue engineering are still *** this study,the assembly of a coiled hydrogel microfiber has shown its capability to encapsulate MSCs and create an engineered tissue model that mimics the multiple lamellae of native *** this model,we investigated the potential of MSCs that were previously induced by ascorbic acid(AA).Compared to non-induced MSCs,AA-induced MSCs exhibited significant increase in AF-associated biomarkers during later development in the engineered AF tissue model and also encouraged collagen accumulation through the down-regulated catabolic gene MMP1 and upregulated anti-catabolic gene ***,AA-induced MSCs exhibited a Col2/Col1 ratio closer to that of a native AF *** results suggested that AA-induced MSCs could be a potential cell source for AF tissue engineering and this established tissue model may provide a simple tool for successful AF tissue engineering strategies in the future.

关键词： closer stem strategies

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给朱剑飞的回信

时代建筑 2006年第5期49卷 67-68页

作者：刘家琨谢诗奇（译）家琨建筑设计事务所主持建筑师不详

你的文章我看了好几遍，我觉得是重要时刻的重要文章。我试写了几次回应，但由于我平时多是对自己的具体实践经验进行总结，并不真正擅长理论概括，所以至今没能如期完成作业。时间这么紧了，干脆就写封回信作为回应吧。

关键词：建筑文化中国西方国家

Gadoxetic acid-enhanced magnetic resonance imaging can predict the pathologic stage of solitary hepatocellular carcinoma

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World Journal of Gastroenterology 2019年第21期25卷 2636-2649页

作者： Yi-Chen Chou I-Ha Lao Pei-Ling Hsieh Ying-Ying Su chee-Wai Mak Ding-Ping Sun Ming-Jen Sheu Hsing-Tao Kuo Tzu-Ju Chen Chung-Han Ho Yu-Ting Kuo Department of Medical Imaging Chi Mei Medical CenterTainan 710Taiwan Department of Optometry Chung Hwa University of Medical TechnologyTainan 717Taiwan Institute of Biomedical Sciences National Sun Yat-sen UniversityKaohsiung 804Taiwan Department of Medical Research Chi-Mei Medical CenterTainan 710Taiwan Department of Hospital and Health Care Administration Chia Nan University of Pharmacy and ScienceTainan 717Taiwan Department of Medical Imaging Kaohsiung Medical University HospitalKaohsiung 807Taiwan Department of Radiology Faculty of MedicineCollege of MedicineKaohsiung Medical UniversityKaohsiung 807Taiwan Biomedical Sciences National Sun Yat-sen UniversityKaohsiung 804Taiwan School of Medicine College of MedicineKaohsiung Medical UniversityKaohsiung 807Taiwan Department of Surgery Chi Mei Medical CenterTainan 710Taiwan Department of Food Science and Technology Chia Nan University of Pharmacy and ScienceTainan 717Taiwan Division of Gastroenterology and Hepatology Department of Internal MedicineChi Mei Medical CenterTainan 710Taiwan Department of Medicinal Chemistry Chia Nan University of Pharmacy and ScienceTainan 717Taiwan Department of Senior Citizen Service Management Chia Nan University of Pharmacy and ScienceTainan 717Taiwan Department of Pathology Chi-Mei Medical CenterTainan 710Taiwan

BACKGROUND Although important for determining long-term outcome, pathologic stage of hepatocellular carcinoma (HCC) is difficult to predict before surgery. Current state-of-the-art magnetic resonance imaging (MRI) using gadoxetic acid provides many imaging features that could potentially be used to classify single HCC as pT1 or pT2. AIM To determine which gadoxetic acid-enhanced MRI (EOB-MRI) findings predict pathologic stage T2 in patients with solitary HCC (cT1). METHODS Pre-operative EOB-MRI findings were reviewed in a retrospective cohort of patients with solitary HCC. The following imaging features were examined: Hyperintensity in unenhanced T2-weighted images, hypointensity in unenhanced T1-weighted images, arterial enhancement, corona enhancement, washout appearance, capsular appearance, hypointensity in the tumor tissue during the hepatobiliary (HB) phase, peritumoral hypointensity in the HB phase, hypointense rim in the HB phase, intratumoral fat, hyperintensity on diffusionweighted imaging, hypointensity on apparent diffusion coefficient map, mosaic appearance, nodule-in-nodule appearance, and the margin (smooth or irregular). Surgical pathology was used as the reference method for tumor staging. Univariate and multivariate analyses were performed to identify predictors of microvascular invasion or satellite nodules. RESULTS There were 39 (34.2%;39 of 114) and 75 (65.8%;75 of 114) pathological stage T2 and T1 HCCs, respectively. Large tumor size (≥ 2.3 cm) and two MRI findings, i.e., corona enhancement [odds ratio = 2.67;95% confidence interval: 1.101-6.480] and peritumoral hypointensity in HB phase images (odds ratio = 2.203;95% confidence interval: 0.961-5.049) were associated with high risk of pT2 HCC. The positive likelihood ratio was 6.25 (95% confidence interval: 1.788-21.845), and sensitivity of EOB-MRI for detecting pT2 HCC was 86.2% when two or three of these MRI features were present. Small tumor size and hypointense rim in the HB phase were rega

关键词： Tumor invasiveness Gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid Hepatobiliary Contrast agent Magnetic resonance imaging Hepatocellular carcinoma

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理想、意识形态、实用智慧——在中国与西方

时代建筑 2006年第5期49卷 63-65页

作者：迈克尔·斯皮克斯吴名（译）谢诗奇（译）杜克大学博士《建筑实录》特约编辑不详

朱剑飞的文章“批评的演化——中国与西方的交流”重要并且及时。我赞同其中的很多观点。然而．为了简要而清楚地说明问题，我想重点讨论我与他的若干分歧，以及这些分歧所衍生的一系列不同的问题。首先，我认为，批评的和后批评的建筑... 详细信息

朱剑飞的文章“批评的演化——中国与西方的交流”重要并且及时。我赞同其中的很多观点。然而．为了简要而清楚地说明问题，我想重点讨论我与他的若干分歧，以及这些分歧所衍生的一系列不同的问题。首先，我认为，批评的和后批评的建筑的区别——由罗伯特·苏摩、莎拉怀汀以及乔治·贝尔德（Robert Somol，Sarah *** Baird）提出．也是朱的文章的基础——是一种误导，它常常将复杂的真实情况简化成静态的意识形态的范畴。这种简化，也出现在最近荷兰代尔夫特大学（Tu—Delft）召开的，为检验后批评对欧洲建筑影响的讨论会上。组织者以及许多与会者都以为会议将是两种不同意识形态之间，”批评性”的拥护者与”后批评性”的支持者之间的一场辩论。事实上这种事情并没有发生．因为那些被称为后批评主义者的几位（包括我、斯坦·艾伦（Stan Allen）、苏摩和怀汀），并没有提出一个后批评的议程或意识形态。这是因为实际上并没有这种东西。如果说，批评性被认为是一种意识形态，要求建筑首先应当批评和抵抗市场，那么后批评是一种主张．

关键词：意识形态西方中国理想智慧欧洲建筑贝尔德讨论会

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迂回隧道开挖对导坑隧道之影响探讨

隧道建设 2007年第S2期27卷 150-154页

作者：陈志南贾儒龙赖正树柯志青台湾科技大学营建系平卡迪贸易有限公司

对于长大隧道而言,全断面隧道钻掘机(TBM)钻掘如施工顺利,可有效缩短工期,惟当遇及特殊地质状况时,亦可能导致TBM受困停工,此时采用迂回隧道绕至TBM机头前方解困是常用之解困方式之一,但迂回隧道挖掘对导坑隧道之影响机制不明,值得探讨... 详细信息

对于长大隧道而言,全断面隧道钻掘机(TBM)钻掘如施工顺利,可有效缩短工期,惟当遇及特殊地质状况时,亦可能导致TBM受困停工,此时采用迂回隧道绕至TBM机头前方解困是常用之解困方式之一,但迂回隧道挖掘对导坑隧道之影响机制不明,值得探讨。故本研究以雪山隧道导坑第十次TBM被埋受困之情况为仿真对象,将导坑视为本研究交叉区段之导坑隧道,利用三维程序FLAC3D探讨迂回隧道施作对导坑隧道之影响。导坑隧道为圆形断面(直径D=5m)、迂回隧道为方形断面(B×B=2m×2m)开挖。依本研究范围内所得之结论如下:由导坑隧道向外垂直破孔处左右两侧区域呈现应力增加趋势,其加压幅度可达初始应力10%~22%。45°破孔进入导坑隧道之锐角侧壁处在破孔后σ1、σ2、σ3分别增加47%、40%、-33.5%,与90°直交侧壁处之调整为20%、18%、6%要高出不少。另外钝角侧壁处其支撑承受之岩压在破孔后σ1、σ2、σ3分别增加21%、11%、-45%。

关键词： TBM 迂回隧道应力集中

Effect of WeiJia on carbon tetrachloride induced chronic liver injury

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World Journal of Gastroenterology 2006年第12期12卷 1912-1917页

作者： Pik-Yuen Cheung QiZhang Gan-Rong Bai Chi-Chun Fong Lin Shi Yue-Feng Shi Meng-SuYang DepartmentofBiology Ya-Ou Zhang Marie chia-Mi Lin Bernard Chan Jay Chun Hsiang-Fu Kung Department of Biology and Chemistry City University of Hong Kong 83 Tat Chee AvenuKowloonHong Kong SARChina Life Science Division Tsinghua University Graduate School at ShenzhenTsinghua CampusUniversity TownShenzhenChina Institute of Molecular Biology The University of Hong KongPokfulamHong KongSARChina Life Tec Enterprise Limited CentralHong KongSARChina The Centre for Emerging Infectious Diseases Faculty of MedicineThe Chinese University of Hong KongShatinN.T.Hong Kong SARChina

AIM： To study the effect of WeiJia on chronic liver injury using carbon tetrachloride （CCh） induced liver injury animal model. METHODS： Wistar rats weighing 180-220g were randomly divided into three groups： normal control group （Group A）, CCh induced liver injury control group （Group B） and CCI4 induction with WeiJia treatment group （Group C）. Each group consisted of 14 rats. Liver damage and fibrosis was induced by subcutaneous injection with 40% CCh in olive oil at 3 mL/kg body weight twice a week for eight weeks for Groups B and C rats whereas olive oil was used for Group A rats. Starting from the third week, Group C rats also received daily intraperitoneal injection of *** at a dose of 1.25 μg/kg body weight. Animals were sacrificed at the fifth week （4 male, 3 female）, and eighth week （4 male, 3 female） respectively. Degree of fibrosis were measured and serological markers for liver fibrosis and function including hyaluronic acid （HA）, type Ⅳ collagen （CIV）, γ-glutamyl transferase （γ-GT）, alanine aminotransferase （ALT） and aspartate aminotransferase （AST） were determined. Alpha smooth muscle actin （α-SMA） and proliferating cell nuclear antigen （PCNA） immunohistochemistry were also performed. RESULTS： CCl4 induction led to the damage of liver and development of fibrosis in Group B and Group C rats when compared to Group A rats. The treatment of WeiJia in Group C rats could reduce the fibrosis condition significantly compared to Group B rats. The effect could be observed after three weeks of treatment and was more obvious after eight weeks of treatment. Serum HA, CIV,ALT, AST and γ-GT levels after eight weeks of treatment for Group C rats were 58±22 μg/L （P〈0.01）, 57±21 μg/L （P〈0.01）, 47±10 U/L （P〈0.01）, 139±13 U/L （P〈0.05） and 52±21 U/L （P〉0.05） respectively, similar to normal control group （Group A）, but significantly different from CCh induced liver injury control group （Group B）. An increase in PCNA and decrease in α-SMA expression level was also obs

关键词： WeiJia Carbon tetrachloride Liver fibrosis