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A Cascade Genetic Algorithm and Particle Swarm Approach for Solving Unit Commitment and Economic Dispatch Problems

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A Cascade Genetic Algorithm and Particle Swarm Approach for ...

Safety and efficacy of Kaffes intraductal self-expanding metal stents in the management of post-liver transplant anastomotic strictures

第二届亚洲机械电子学学术会议

作者： Siew Chin Neoh Norhashimah Morad chee peng lim Zalina Abdul Aziz School of Electrical and Electronic Engineering Universiti Sains Malaysia Engineering Campus Nibong Tebal 14300 Pulau Pinang Malaysia

Unit commitment and economic dispatch are two important decisions in thermal power generation scheduling. The tasks involve determination and allocation of power generation to thermal units that minimize the total power generation cost and satisfy the production *** paper presents a cascade Genetic Algorithm and Particle Swarm Optimization(GA-PSO)approach for solving thermal power generation scheduling based on a layered matrix encoding *** proposed hybrid method is compared to layered matrix encoding GA using the thermal power generation problem given in Williams[1]to demonstrate its effectiveness in generating an optimal,cost-effective power generation *** results showed that cascade GA-PSO outperformed the layered matrix encoding GA in minimizing the total power production cost for unit commitment and power dispatch problems.

关键词： Particle Swarm Optimization Genetic Algorithms Thermal Power Scheduling

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World Journal of Transplantation 2024年第2期14卷 88-98页

作者： chee lim Jonathan Ng Babak Sarraf Rhys Vaughan Marios Efthymiou Leonardo Zorron Cheng Tao Pu Sujievvan Chandran Department of Gastroenterology and Hepatology Austin HealthMelbourne HeidelbergVIC 3084Australia Melbourne Medical School The University of MelbourneMelbourne ParkvilleVIC 3052Australia

BACKGROUND Endoscopic management is the first-line therapy for post-liver-transplant anas-tomotic *** the optimal duration of treatment with plastic stents has been reported to be 8-12 months,data on safety and duration for metal stents in this setting is *** to limited access to endoscopic retrograde cholan-giopancreatography(ERCP)during the coronavirus disease 2019 pandemic in our centre,there was a change in practice towards increased usage and length-of-stay of the Kaffes biliary intraductal self-expanding stent in patients with suitable *** was mainly due to the theoretical benefit of Kaffes stents allowing for longer indwelling periods compared to the traditional plastic *** Adult liver transplant recipients aged 18 years and above who underwent ERCP were retrospectively identified during a 10-year period through a database *** admissions post-Kaffes stent insertion were identified manually through electronic and scanned medical *** main outcome was the incidence of complications when stents were left indwelling for 3 months vs 6 *** efficacy was calculated via rates of stricture recurrence between patients that had stenting courses for≤120 d or>120 *** During the study period,a total of 66 ERCPs with Kaffes insertion were performed in 54 patients throughout their stenting *** 33 ERCPs,the stent was removed or exchanged on a 3-month *** pancreatitis,perfor-ations or deaths *** post-ERCP complications were similar between the 3-month(abdominal pain and intraductal migration)and 6-month(abdominal pain,septic shower and embedded stent)groups-6.1%vs 9.1%respectively,P=*** strictures resolved at the end of the stenting course,but the stenting course was variable from 3 to 22 *** recurrence rate for stenting courses lasting for up to 120 d was 71.4%and 21.4%for stenting courses of 121 d or over(P=0.03).There were 28 patients that were treated with a sin

关键词： Liver transplantation Cholangiopancreatography Endoscopic retrograde Constriction Pathologic Self expandable metallic stents Bile duct diseases Cholestasis

Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2119-2136页

作者： Li peng Yanyi Jiang Hengxing Chen Yongqiang Wang Qiusheng Lan Shuiqin Chen Zhanwang Huang Jingyuan Zhang Duanqing Tian Yuntan Qiu Diankui Cai Jiangyun peng Daning Lu Xiaoqing Yuan Xianzhu Yang Dong Yin Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Medical Research Center Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Hefei Institutes of Physical Science Chinese Academy of SciencesHefei 230031China Department of Gastrointestinal Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Department of Hepatobiliary Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China

Transcriptional dysregulation of genes is a hallmark of tumors and can serve as targets for cancer drug ***,it is extremely challenging to develop small-molecule inhibitors to target abnormally expressed transcription factors(TFs)except for the nuclear receptor family of *** is known about the interaction between TFs and transcription cofactors in gastroesophageal adenocarcinoma(GEA)or the therapeutic effects of targeting TF and transcription cofactor *** this study,we found that ETS homologous factor(EHF)expression is promoted by a core transcriptional regulatory circuitry(CRC),specifically ELF3-KLF5-GATA6,and interference with its expression suppressed the malignant biological behavior of GEA ***,we identified Ajuba lim protein(AJUBA)as a new coactivator of EHF that cooperatively orchestrates transcriptional network activity in ***,we identified KRAS signaling as a common pathway downstream of EHF and ***,dual targeting of EHF and AJUBA by lipid nanoparticles cooperatively attenuated the malignant biological behaviors of GEA in vitro and in *** conclusion,EHF is upregulated by the CRC and promotes GEA malignancy by interacting with AJUBA through the KRAS *** of both EHF and its coactivator AJUBA through lipid nanoparticles is a novel potential therapeutic strategy.

关键词： EHF AJUBA KRAS pathway Enhancer Core transcriptional regulatory circuitry Gastroesophageal adenocarcinoma Gastric adenocarcinoma Esophageal adenocarcinoma Transcription factor Coactivator Lipid nanoparticles

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儒家智德思想赋能智能时代大学生道德教育

教育文化论坛 2024年第2期16卷 77-86页

作者：孙雷林志敏拉曼大学中华研究院马来西亚吉隆坡43200 海口经济学院网络学院海南海口571100

人工智能的发展影响着人类社会的各个领域,特别是ChatGPT的出现,给教育领域带来了变革。先进的人工智能技术与海量的数据信息为教育提供了更多与更好的技术支持,然而也给学校的思想道德教育带来了前所未有的挑战。教育是兴邦之本,教育... 详细信息

人工智能的发展影响着人类社会的各个领域,特别是ChatGPT的出现,给教育领域带来了变革。先进的人工智能技术与海量的数据信息为教育提供了更多与更好的技术支持,然而也给学校的思想道德教育带来了前所未有的挑战。教育是兴邦之本,教育承担着人才培养、文化传承与社会服务等历史使命,德育是教育的重中之重。通过分析智能时代大学生的道德教育面临新的挑战,提出以儒家“智德”思想赋能“智能”时代大学生道德教育,从儒家“智德”思想中总结出五重价值:明辨是非,知耻明辱;仁者爱人,以智辅仁;学而知之,崇智明德;仁智并重,从善利他;敬德修业,知行并进。

关键词：智能时代儒家智德大学生道德教育

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Rapid Repair of Earthquake Damaged RC Interior Beam-wide Column Joints and Beam-wall Joints Using FRP Composites

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四川大学学报（工程科学版） 2009年第3期41卷 258-265页

作者： LI Bing lim chee Leong Inst. for the Environment Nanyang Technological Univ. Singapore

This paper studies the seismic performance of FRP-strengthened RC interior non-seismically detailed beam-wide columns and beam-wall joints after limited seismic *** eccentric and concentric beam-wide column joints and two beam-wall joints,initially damaged in a previous study,were repaired and tested under constant axial loads(0.1fc′Ag and 0.35fc′Ag) and lateral cyclic *** rapid repair technique developed,aimed to restore the original strength and to provide minimum drift *** repair schemes were characterized by the use of:(a) epoxy injections and polymer modified cementitious mortar to seal the cracks and replace spalled concrete;and(b) glass(GFRP) and carbon(CFRP) sheets to enhance the joint *** FRP sheets were effectively prevented against possible debonding through the use of fiber *** between responses of specimens before and after repair clearly indicated reasonable restoration in strength,drift capacity,stiffness and cumulative energy dissipation *** specimens failed with delamination of FRP sheets at beam-column joint *** rapid repair technique developed in this study is recommended for mass upgrading or repair of earthquake damaged beam-column joints.

关键词： FRP 建筑物抗震设计抗震结构

A hybrid Jacobian control for uncalibrated robot visual servoing

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Progress in Natural Science:Materials International 2005年第6期15卷 564-568页

作者： TEO chee-Leong,lim Siak-Piang Department of Mechanical Engineering National University of Singapore Singapore 117576 Department of Mechanical Engineering National University of Singapore Singapore 117576

This paper focuses on the visual servo control of an uncalibrated robotic arm with an eye-in-hand camera. Without a prior knowledge of the kinematics of the robotic arm or camera calibration, the proposed hybrid Jacobian controller can track a moving object using visual feedback and joint-space velocity feedback. The proposed hybrid control method is a combination of the uncalibrated visual servoing and approximate Jacobian feedback control. First, the Jacobian matrix from joint-space to image-space is estimated by recursive least-squares (RLS) algorithm, and then the approximate Jacobian feedback controller is designed by using visual feedback and joint-space velocity feedback. The performances of the proposed control methods are illustrated by computer simulations.

关键词： robot control uncalibrated visual servoing Jacobian control.

Unique and conserved features of floral evocation in legumes

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Journal of Integrative Plant Biology 2014年第8期56卷 714-728页

作者： lim chee Liew Mohan B. Singh Prem L. Bhalla Plant Molecular Biology and Biotechnology Laboratory Melbourne School of Land and Environment University of Melbourne

Legumes, with their unique ability to fix atmo- spheric nitrogen, play a vital role in ensuring future food security and mitigating the effects of climate change because they use less fossil energy and produce less greenhouse gases compared with N-fertilized systems. Grain legumes are second only to cereal crops as a source of human and animal food, and they contribute approximately one third of the protein consumed by the human population. The productivityof seed crops, such as grain legumes, is dependent on flowering. Despite the genetic variation and importance of flowering in legume production, studies of the molecular pathways that control flowering in legumes are limited. Recent advances in genomics have revealed that legume flowering pathways are divergent from those of such model species as Arabidopsis thaliana. Here, we discuss the current understanding of flowering time regulation in legumes and highlight the unique and conserved features of floral evocation in legumes.

关键词： Flowering legume soybean

Mitochondrial homeostasis in Parkinson＇s disease-a triumvirate rule？

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Neural Regeneration Research 2017年第8期12卷 1270-1272页

作者： chee-Hoe Ng Liting Hang Kah-Leong lim National Neuroscience Institute Singapore Neuroscience & Behavioral Disorders Program Duke-NUSMedical School Singapore Department of Physiology National University of SingaporeSingapore NUS Graduate School for Integrative Sciences and Engineering Singapore

Mitochondrial dysfunction in Parkinson＇s disease：Mitochondria are the primary energy generator of the cell and they are important for cell survival and *** mitochondrial homeostasis is frequently reported in human d... 详细信息

关键词： PPAR PD cell PGC AMPK Mitochondrial homeostasis in Parkinson’s disease-a triumvirate rule

Advances of macroalgae biomass for the third generation of bioethanol production

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Chinese Journal of Chemical Engineering 2020年第2期28卷 502-517页

作者： Inn Shi Tan Man Kee Lam Henry chee Yew Foo Steven lim Keat Teong Lee Department of Chemical Engineering Curtin UniversitySarawak Campus CDT 25098009 MiriSarawakMalaysia Chemical Engineering Department Universiti Teknologi PETRONAS32610 Seri IskandarPerakMalaysia Centre for Biofuel and Biochemical Research Institute of Self-Sustainable BuildingUniversiti Teknologi PETRONAS32610 Seri IskandarPerakMalaysia Department of Chemical Engineering Lee Kong Chian Faculty of Engineering and ScienceUniversiti Tunku Abdul Rahman43000SelangorMalaysia School of Chemical Engineering Universiti Sains MalaysiaEngineering CampusSeri Ampangan14300 Nibong TebalPulau PinangMalaysia

In recent years, utilization of renewable sources for biofuel production is gaining popularity due to growing greenhouse gas(GHG) emissions which causes global warming. There has been a great effort in exploring alternative feedstock for bioethanol production. In this context, the production of third-generation bioethanol from macroalgae has emerged as an alternative feedstock to food crop-based starch and lignocellulosic *** is mainly due to the fast growth rate of macroalgae, no competition with agricultural land, high carbohydrate content and relatively simple processing steps compared to lignocellulosic biomass. This review paper provides an insight of recent innovative approaches for macroalgae bioethanol production, including conventional and advanced hydrolysis process to produce fermentable sugar, various fermentation technologies, economic analysis and life cycle assessment. With the current technology maturity, efficient utilization of macroalgae as sustainable source for bioethanol and other value-added chemicals production could be achieved in the near future.

关键词： Macroalage Hydrolysis Biomass Fermentation Bioethanol