检索结果-南通市图书馆

china Ocean Engineering 2020年第1期34卷 21-29页

作者： MENG Shuai cheN Yong che chi-dong State Key Laboratory of Ocean Engineering Collaborative Innovation Center for Advanced Ship and Deep-sea ExplorationShanghai Jiao Tong UniversityShanghai 200240China Shanghai Marine Diesel Engine Research Institute Shanghai 200240China

As drilling operations move into remote locations and extreme water depths, recoil analysis requires more careful considerations and the incidence of emergency disconnect is increased inevitably. To accurately capture the recoil dynamics of a deep-water riser in an emergency disconnect scenario, researchers typically focus on modelling the influential subsystems (e.g., the tensioner, the mud discharge and seawater refilling process) which can be solved in the preprocessing, and then the determined parameters are transmitted into an existing global riser analysis software. Distinctively, the current study devotes efforts into the coupling effects resulting from that the suspended riser reacts the platform heave motion via the tensioner system in the course of recoil and the discharging fluid column follows the oscillation of the riser in the mud discharge process. Four simulation models are established based on lumped mass method employing different formulas for the top boundary condition of the riser and the discharging flow acceleration. It demonstrates that the coupling effects discussed above can significantly affect the recoil behavior during the transition phase from initial disconnect to the final hang-off state. It is recommended to develop a fully- coupled integrated model for recoil analysis and anti-recoil control system design before extreme deep-water applications.

关键词： recoil analysis emergency disconnect coupling effect platform excitation

Organic near-infrared optoelectronic materials and devices:an overview

在线全文

学校读者我要写书评

暂无评论

Advanced Photonics 2024年第1期6卷 17-42页

作者： Zong-Lu che Chang-Cun Yan Xue-dong Wang Liang-Sheng Liao Soochow University Institute of Functional Nano and Soft Materials(FUNSOM)Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSuzhouChina Soochow University College of ChemistryChemical Engineering and Materials ScienceJiangsu Engineering Laboratory of Novel Functional Polymeric MaterialsSuzhouChina Macao University of Science and Technology Macao Institute of Materials Science and EngineeringMacaoChina

Near-infrared(NIR)light has shown great potential for military and civilian applications owing to its advantages in the composition of sunlight,invisibility to human eyes,deeper penetration into biological tissues,and low optical loss in optical ***,organic optoelectronic materials that can absorb or emit NIR light have aroused great scientific interest in basic science and practical *** on these NIR organic optoelectronic materials,NIR optoelectronic devices have been greatly improved in performance and *** this review,the representative NIR organic optoelectronic materials used in organic solar cells,organic photodetectors,organic light-emitting diodes,organic lasers,and organic optical waveguide devices are briefly introduced,and the potential applications of each kind of device are briefly ***,we summarize and take up the development of NIR organic optoelectronic materials and devices.

关键词： near-infrared organic optoelectronic materials organic solar cells organic light-emitting devices organic optical waveguides

Silicone oil as a corneal lubricant to reduce corneal edema and improve visualization during

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第1期17卷 92-96页

作者： Dan-Yang che Zhu-Lin Chan Ji-Bo Zhou dong-Qing Zhu Department of Ophthalmology Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China College of Health Science and Technology Shanghai Jiao Tong University School of MedicineShanghai 200011China The PLA Navy Anqing Hospital Anqing 246004Anhui ProvinceChina

AIM:To evaluate the efficacy and safety of silicone oil(SO)as a corneal lubricant to improve visualization during ***:Patients who underwent vitreoretinal surgery were divided into two *** 1 was operated on with initial SO(Oxane 5700)as a corneal *** 2 was operated on with initial lactated ringer’s solution(LRS)and then replaced with SO as *** clarity was scored during the *** staining was performed to determine the damage to corneal ***:Totally 114 eyes of 114 patients were *** SO use maintained a clear cornea and provided excellent visualization of surgical *** group 1,the fundus clarity was grade 3 in 41/45 eyes and grade 2 in 4/45 *** group 2,corneal edema frequently occurred after initial LRS *** fundus clarity was grade 3 in 19/69 eyes,2 in 37/69 eyes and 1 in 13/69 eyes(P0.05).CONCLUSION:The use of SO as a corneal lubricant is effective and safe for preserving and improving corneal clarity and providing clear surgical field during vitrectomy.

关键词： silicone oil corneal lubricant corneal edema vitrectomy

Carbene-catalyzed enantioselective seleno-Michael addition as access to antimicrobial active Se-containing heterocycles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science china chemistry 2024年第7期67卷 2199-2205页

作者： Hongyan Long Sha Zhao Chunyan Jian Xiuli Wu Fengfei Lu Minghong Liao Fengrui che Xingxing Wu Yonggui Robin chi State Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityGuiyang 550025China School of chemistry Chemical Engineeringand BiotechnologyNanyang Technological UniversitySingapore 637371Singapore

Organoseleniums exhibit a diverse set of biological activities that are pivotal for drug discovery and are widely explored in synthetic chemistry and material *** many transformations have been developed for non-enantioselective C–Se bond formations,the catalyst-controlled stereoselective preparation of chiral organoseleniums continues to be of considerable *** particular,there are limited studies on the enantioselective seleno-Michael addition reactions to access chiral selenium functional ***,we disclose a carbene-catalyzed highly enantioselective nucleophilic C–Se bond construction through formal[3+3]annulations between selenocarboxamides and bromoenals,affording seleno-thiazinone products with good yields and excellent *** choice of a weak inorganic base was pivotal to suppressing the unproductive racemization and decomposition of the selenium ***,the catalytically generated chiral selenium-containing heterocyclic products feature remarkable antimicrobial activities that could serve as promising lead scaffolds for further agrochemical development.

关键词： seleno-Michael addition organocatalysis N-heterocyclic carbene seleno-heterocycles antimicrobial activity

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

基于复合阻尼的声学覆盖层吸声效率计算

舰船科学技术 2022年第5期44卷 32-36页

作者：张帆车驰东上海交通大学船舶海洋与建筑工程学院上海200240

为了提高声学覆盖层的仿真精度,改进原有的计算参数模型。基于集总参数法和传递矩阵法,提出声学覆盖层的一维等效模型。结合有限元法对声学覆盖层计算,计算结果表明,阻尼对吸声效率有显著作用,不同类型阻尼对吸声作用不同,结构阻尼主要... 详细信息

为了提高声学覆盖层的仿真精度,改进原有的计算参数模型。基于集总参数法和传递矩阵法,提出声学覆盖层的一维等效模型。结合有限元法对声学覆盖层计算,计算结果表明,阻尼对吸声效率有显著作用,不同类型阻尼对吸声作用不同,结构阻尼主要影响低频区,粘性阻尼主要影响高频段。根据橡胶材料特性,结合数值计算的结果,提出一种计权的复合阻尼模型,并通过声管实验验证了有效性。提高了声学覆盖层的仿真精度,对声学覆盖层设计有重要意义。

关键词：声学覆盖层复合阻尼吸声效率声管实验

Protective effects of baffles with different positions,row spacings,heights on debris flow impact

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第7期21卷 2352-2367页

作者： SUN Xinpo cheN Min BI Yuzhang ZHENG Lu che chi XU Ao TIAN Zijian JIANG Zheyuan College of Civil Engineering Sichuan University of Science and EngineeringZigong 643000China College of Resources and Environment Fujian Agriculture and Forestry UniversityFuzhou 350002China School of Civil Engineering Fuzhou UniversityFuzhou 350108China Jiangsu Key Laboratory of Urban Underground Engineering&Environmental Safety Institute of Geotechnical EngineeringSoutheast UniversityNanjing 210096China Beijing Urban Construction Science Technology Promoting Association Beijing 100055China SUSE-BZ Geoenvironmental Engineering Joint Laboratory Sichuan University of Science and EngineeringZigong 643000China

The baffle effectively slowed down debris flow velocity,reduced its kinetic energy,and significantly shortened the distance of debris flow ***,they are widely used for protection against natural hazards such as landslides and *** study,based on the threedimensional DEM(Discrete Element Method),investigated the impact of different baffle positions on debris flow *** flow velocity and kinetic energy variations were studied through single-factor *** baffle positions were preliminarily selected by analyzing the influence of the first-row baffle position on the impact force and accumulation mass of debris ***,based on the selected baffle positions and four factors influencing the effectiveness of baffle protection(baffle position(P),baffle height(h),row spacing(S_(r)),and angle of transit area(α)),an orthogonal design was employed to further explore the optimal arrangement of *** research results indicate that the use of a baffle structure could effectively slow down the motion velocity of debris flows and dissipate their *** the baffle is placed in the transit area,the impact force on the first-row baffle is greater than that when the baffle is placed in the deposition ***,when the baffle is placed in the transit area,the obstruction effect on debris flow mass is also greater than that when the baffle is placed in the deposition *** orthogonal experimental range analysis,when the impact on the first row of baffles is used as the evaluation criterion,the importance of each influencing factor is ranked asα>P>S_(r)>*** the mass of debris flow behind the baffle is regarded as the evaluation criterion,the rank is changed to P>α>S_(r)>*** experimental simulation results show that the optimal baffle arrangement is:P_(5),S_(r)=16,α=35°,h=9.

关键词： Debris flow Baffle Protective effect Discrete element

Experimental and Numerical Study on Vibration of the Full-Revolving Propulsion Ship Stern

在线全文

学校读者我要写书评

暂无评论

china Ocean Engineering 2015年第1期29卷 33-48页

作者：刘长卿车驰东沈小寒 State Key Laboratory of Ocean Engineering School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong University

In order to solve the severe vibration problems of an ocean engineering ship with a full-revolving propulsion system, the navigation tests, including forced vibration response test and modal test, are carded out in its stem. It is concluded from the comparison of the time-domain waveform and spectrum from different measurement points that three main factors lead to a high-level stern vibration. Firstly, the specific dynamic stiffness of a water tank is relatively small compared with its neighbor hold, which makes it act like a vibration isolator preventing vibrational energy transmitting to the main hold. Secondly, there exists high-density local modes in the working frequency range of the main engine and thus the local resonance occurs. Thirdly, the abnormal engagement of gears caused by the large deflection of the shaft bearing due to its low mounting rigidity leads to violent extra impulse excitations at high speeds. Then the modification against the dynamic defects is given by simply improving the specific stiffness of the water tanks. And the effect is validated by the FEM calculation. Some important experience is obtained with the problems being solved, which is useful in the design of ships with the same propulsion system. It is also believed that the dynamic consideration is as important as the static analysis for the ships, and that most of the vibration problems may be avoided with a proper acoustic design.

关键词： full-revolving propulsion stern vibration navigation test modal identification acoustic design

Reynosin protects neuronal cells from microglial neuroinflammation by suppressing NLRP3 inflammasome activation mediated by NADPH oxidase

在线全文

学校读者我要写书评

暂无评论

chinese Journal of Natural Medicines 2024年第6期22卷 486-500页

作者： YANG Yanqiu che Yue FANG Mingxia YAO Xiaohu ZHOU Di WANG Feng cheN Gang LIANG dong LI Ning HOU Yue Key Laboratory of Bioresource Research and Development of Liaoning Province College of Life and Health SciencesNorth-eastern UniversityShenyang 110000China National Frontiers Science Center for Industrial Intelligence and Systems Optimization Key Laboratory of Data Analytics and Optimization for Smart IndustryMinistry of EducationNortheastern UniversityShenyang 110000China School of Traditional chinese Materia Medica Key Laboratory of Innovative Traditional Chinese Medicine for Major Chronic Diseases of Liaoning provinceKey Laboratory for TCM Material Basis Study and Innovative Drug Development of Shenyang CityShenyang Pharmaceutical UniversityShenyang 110000China State Key Laboratory for chemistry and Molecular Engineering of Medicinal Resources School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilin 541000China

Neuroinflammation,mediated by the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing-3(NLRP3)inflammasome,is a significant contributor to the pathogenesis of neurodegenerative diseases(NDDs).Reynos-in,a natural sesquiterpene lactone(SL),exhibits a broad spectrum of pharmacological effects,suggesting its potential therapeutic ***,the effects and mechanism of reynosin on neuroinflammation remain *** current study explores the effects and mechanisms of reynosin on neuroinflammation using mice and BV-2 microglial cells treated with lipopolysaccharide(LPS).Our findings reveal that reynosin effectively reduces microglial inflammation in vitro,as demonstrated by decreased CD11b expression and lowered interleukin-1 beta(IL-1β)and interleukin-18(IL-18)mRNA and protein ***,in vivo,results showed a re-duction in the number of Iba-1 positive cells and alleviation of morphological alterations,alongside decreased expressions of IL-1βand *** analysis indicates that reynosin inhibits NLRP3 inflammasome activation,evidenced by reduced transcription of NLRP3 and caspase-1,diminished NLRP3 protein expression,inhibited apoptosis-associated speck-like protein containing a CARD(ASC)oli-gomerization,and decreased caspase-1 ***,reynosin curtailed the activation of nicotinamide adenine dinuc-leotide phosphate(NADPH)oxidase,demonstrated by reduced NADP^(+)and NADPH levels,downregulation of gp91^(phox) mRNA,pro-tein expression,suppression of p47^(phox) expression and translocation to the ***,reynosin exhibited a neuroprotective effect against microglial inflammation in vivo and in *** collective findings underscore reynosin’s capacity to mitigate mi-croglial inflammation by inhibiting the NLRP3 inflammasome,thus highlighting its potential as a therapeutic agent for managing neuroinflammation.

关键词： Microglia NLRP3 inflammasome Reactive oxygen species NADPH oxidase Neuron Reynosin

Cell replacement with stem cell-derived retinal ganglion cells from different protocols

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 807-810页

作者： Ziming Luo Kun-che Chang Spencer Center for Vision Research Byers Eye InstituteStanford University School of Medicine Department of Ophthalmology Louis J.Fox Center for Vision RestorationUniversity of Pittsburgh School of Medicine Department of Neurobiology Center of NeuroscienceUniversity of Pittsburgh School of Medicine

Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness *** is currently no cure for vision loss in glaucoma because retinal ganglion cells do not regenerate and are not replaced after *** stem cell-derived retinal ganglion cell transplant is a potential therapeutic strategy for retinal ganglion cell degenerative *** this review,we first discuss a 2D protocol for retinal ganglion cell differentiation from human stem cell culture,including a rapid protocol that can generate retinal ganglion cells in less than two weeks and focus on their transplantation ***,we discuss using 3D retinal organoids for retinal ganglion cell transplantation,comparing cell suspensions and *** review provides insight into current knowledge on human stem cell-derived retinal ganglion cell differentiation and transplantation,with an impact on the field of regenerative medicine and especially retinal ganglion cell degenerative diseases such as glaucoma and other optic neuropathies.

关键词： cell clumps cell suspension cell transplantation differentiation direct-induced protocol glaucoma optic neuropathy regenerative medicine retinal ganglion cell retinal organoids stem cells

Numerical investigation of transient gas–solid heat transfer in a packed bed:Impact of intra-particle thermal diffusion

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第7期90卷 404-411页

作者： Hanqiao che Yuanhe Yue Zhaohua Jiang Duan Li School of Mechanical Engineering Guangxi UniversityNanningGuangxi530004China School of chemical Engineering University of BirminghamBirminghamB152TTUK Hebei Engineering Research Center of Advanced Energy Storage Technology and Equipment School of Energy and Environmental EngineeringHebei University of TechnologyTianjin300401China Hebei Key Laboratory of Thermal Science and Energy Clean Utilization School of Energy and Environmental EngineeringHebei University of TechnologyTianjin300401China School of Mechatronics and Vehicle Engineering Chongqing Jiaotong UniversityChongqing400074China School of Instrumentation and Opto-Electronic Engineering Beihang UniversityBeijing 100191China

The transient heat transfer behaviours in a packed bed have been studied using coupled computational fluid dynamics(CFD)and discrete element method(DEM).Intra-particle thermal diffusion,which is a crucial but rarely explored issue,is considered by introducing a one-dimensional diffusion equation in the DEM *** achieve a sufficiently long physical time of simulations,we further reduce the computational cost by applying periodic boundary condition to a small segment of the packed *** study demonstrates a shifting peak heat flow rate from the bottom to the top of the packed bed during the initial warming *** affirm that the influence of thermal diffusion within a particle is noteworthy only for particles exhibiting a high Biot number(e.g.,Bi=1.2).This insight enriches our understanding of heat transfer mechanisms in packed beds and their practical engineering applications.

关键词： Packed bed Intra-particle heat transfer CFD–DEM