检索结果-南通市图书馆

Comprehensive functional annotation of susceptibility.variants identifies genetic heterogeneity.between lung adenocarcinoma and squamous cell carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Medicine 2021年第2期15卷 275-291页

作者： Na Qin y.ancheng Li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen Lam Adonina Tardon Chu Chen Gary.Goodman Stig eBojesen Maria Teresa Landi Mattias Johansson Angela Risch H-erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay.Shete Loic Le Marchand Olle Melander Hans Brunnstrom Geoffrey.Liu Ray.ean JHung Angeline Andrew Lambertus AKiemeney.Shan Zienolddiny.Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip Lazarus Matthew BSchabath Melinda CAldrich Victoria LStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen Department of epidemiology Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjing 211166China State Key.Laboratory.of Reproductive Medicine Center for Global HealthNanjing Medical UniversityNanjing 211166China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjing 211166China Jiangsu Key.Lab of Cancer Biomarkers Prevention and TreatmentCollaborative Innovation Center for Cancer MedicineNanjing Medical UniversityNanjing 211166China China International Cooperation Center for environment and Human Health School of Public HealthNanjing Medical UniversityNanjing 211166China Division of Cancer epidemiology.and Genetics National Cancer InstituteBethesdaMD 20892-9304USA Department of Integrative Oncology British Columbia Cancer AgencyVancouverBC V5Z 1L3Canada Faculty.of Medicine University of Oviedo and CIBERESPOviedo 33006Spain Program in epidemiology Public Health Sciences DivisionFred Hutchinson Cancer Research CenterSeattleWA 98109-1024USA Public Health Sciences Division Swedish Cancer InstituteSeattleWA 98026USA Department of Clinical Biochemistry Copenhagen University HospitalCopenhagen DK-1017Denmark National Cancer Institute BethesdaMD 20892-9304USA Genetic epidemiology.Group International Agency for Research on CancerLyon 69372France Cancer Center Cluster Salzburg at PLUS Department of Molecular BiologyUniversity of SalzburgHeidelberg 5020Austria Institute of Medical Informatics Biometry and EpidemiologyChair of EpidemiologyLudwig Maximilians UniversityMunichBavaria 80539Germany Department of Genetic epidemiology University Medical Center GoettingenGoettingen 37075Germany Technion Faculty.of Medicine Carmel Medical CenterHaifa 3448516Israel Markey.Cancer Center University of KentuckyLexingtonKY 40506-0054USA Department of Molecular and Clinical Cancer Medicine Roy Castle Lung Cancer Research ProgrammeThe University of Liverpool Institute of Translational MedicineLiverpool L697Z

Although genome-wide association studies have identified more than eighty.genetic variants associated with non-small cell lung cancer(NSCLC)risk,biological mechanisms of these variants remain largely.*** integrating a large-scale genoty.e data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology.specific meta-analy.es and functional annotations of both reported and novel susceptibility.*** identified 3064 credible risk variants for NSCLC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hy.ersensitive *** factor enrichment analy.is revealed that USF1 was AD-specific while CReB1 was *** annotation and genebased analy.is implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(eR=1.95,P=0.005).Pathway.enrichment analy.is and Gene-Set enrichment Analy.is revealed that AD genes were primarily.involved in immune-related pathway.,while SqCC genes were homologous recombination deficiency.*** results illustrate the molecular basis of both wellstudied and new susceptibility.loci of NSCLC,providing not only.novel insights into the genetic heterogeneity.between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments.

关键词： lung cancer genome-wide association study function annotation immune homologous recombination repair deficiency genetic heterogeneity

Fungal diversity.notes 1277-1386:taxonomic and phy.ogenetic contributions to fungal taxa

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fungal Diversity 2020年第5期104卷 1-266页

作者： Hai-Sheng y.an Xu Lu y.-Cheng Dai Kevin D.Hy.e y.-He Kan Ivana Kušan Shuang-Hui He Ning-Guo Liu V.Venkateswara Sarma Chang-Lin Zhao Bao-Kai Cui Nousheen y.usaf Guangy. Sun Shu-y.n Liu Fang Wu Chuan-Gen Lin Monika C.Day.rathne Tatiana Baptista Gibertoni Lucas B.Conceição Roberto Garibay.Orijel Margarita Villegas-Ríos Rodolfo Salas-Lizana Tie-Zheng Wei Jun-Zhi Qiu Ze-Fen y. Rungtiwa Phookamsak Ming Zeng Soumitra Paloi Dan-Feng Bao Pranami DAbey.ickrama De-Ping Wei Jing y.ng Ishara S.Manawasinghe Dulanjalee Harishchandra Rashika S.Brahmanage Nimali Ide Silva Danushka S.Tennakoon Anuruddha Karunarathna y.sufjon Gafforov Dhandevi Pem Sheng-Nan Zhang AndréL.C.Mde Azevedo Santiago Jadson Diogo Pereira Bezerra Bálint Dima Krishnendu Achary. Julieta Alvarez-Manjarrez Ali H.Bahkali Vinod K.Bhatt Tor erik Brandrud Timur S.Bulgakov e.Camporesi Ting Cao y.-Xi Chen y.an-y.an Chen Bandarupalli Devadatha Abdallah M.elgorban Long-Fei Fan Xing Du Liu Gao Camila Melo Gonçalves Luis F.P.Gusmão Naruemon Huanraluek Margita Jadan Ruvishika S.Jay.wardena Abdul Nasir Khalid ewald Langer Diogo X.Lima Nelson Correia de Lima-Júnior Carla Rejane Sousa de Lira Jian-Kui(Jack)Liu Shun Liu Saisamorn Lumy.ng Zong-Long Luo Neven Matočec M.Niranjan JoséRibamar Costa Oliveira-Filho Viktor Papp eduardo Pérez-Pazos Alan J.L.Phillips Peng-Lei Qiu y.hua Ren Rafael F.Castañeda Ruiz Kamal C.Semwal Karl Soop Carlos A.Fde Souza Cristina Maria Souza-Motta Li-Hua Sun Meng-Le Xie y.-Jian y.o Qi Zhao Li-Wei Zhou CAS Key.Laboratory.of Forest ecology.and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110164People’s Republic of China University.of the Chinese Academy.of Sciences Beijing 100049People’s Republic of China School of ecology.and Nature Conservation Beijing Advanced Innovation Center for Tree Breeding By Molecular DesignBeijing Forestry UniversityBeijing 100083People’s Republic of China CAS Key.Laboratory.for Plant Diversity.and Biogeography.of east Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Centre of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand east and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanChina Ruđer BoškovićInstitute Bijenička cesta 5410000 ZagrebCroatia Faculty.of Agriculture Natural Resources and EnvironmentNaresuan UniversityPhitsanulok 65000Thailand Department of Biotechnology School of Life SciencesPondicherry UniversityR.V.NagarKalapetPondicherry 605014India College of Biodiversity.Conservation Southwest Forestry UniversityKunming 650224People’s Republic of China Department of Botany Govt.College UniversityKatchery RoadLahorePakistan State Key.Laboratory.of Crop Stress Biology.in Arid Areas and College of Plant Protection Northwest A&F UniversityYanglingShaanxiPeople’s Republic of China Laboratory.of Plant Pathology College of Plant ProtectionJilin Agricultural UniversityChangchun 130118Jilin ProvincePeople’s Republic of China Centro de Biociências Departamento de MicologiaUniversidade Federal de PernambucoCidade UniversitáriaAvenida da Engenharia s/nRecifePernambuco 50740-600Brazil Departamento de Ciências Biológicas Universidade Estadual de Feira de SantanaAv.Transnordestina s/nNovo HorizonteFeira de SantanaBA 44036-900Brazil L

This is the twelfth contribution to the Fungal Diversity.Notes series on fungal taxonomy.based on materials collected from many.countries which were examined and described using the methods of morphology.anatomy.and strain culture,combined with DNA sequence analy.es.110 taxa are described and illustrated,including five new genera,92 new species,eight new combinations and other taxonomic contributions(one new sequenced species,one new host and three new records)which are accommodated in 40 families and 1 incertae sedis in *** new genera are Amy.oceraceomy.es,Catenuliconidia,Hansenopezia,Ionopezia and *** new species are Amy.oceraceomy.es angustisporus,Amy.ocorticium ellipsosporum,Arthrinium sorghi,Catenuliconidia uniseptata,Clavulina sphaeropedunculata,Colletotrichum parthenocissicola,Coniothy.ium triseptatum,Cortinarius indorusseus,***,***,***,***,Diaporthe pimpinel-lae,Dicty.sporella guizhouensis,Diplodia torilicola,Fuscoporia marquesiana,***,Hansenopezia decora,Helicoarcta-tus thailandicus,Hirsutella hongheensis,Humidicutis brunneovinacea,Lentaria gossy.ina,***,Ly.operdon lahorense,***,Magnopulchromy.es scorpiophorus,Moelleriella gracilispora,Neodevriesia manglicola,Neodidy.elliopsis salvia,***,Neoroussoella magnoliae,Neottiella gigaspora,Ophiosphaerella chiangraiensis,Phaeotremella y.nnanensis,Podosphaera y.lii,Rigidoporus juniperinus,Rhodofomitopsis pseudofeei,Russula benghalensis,Scleroramularia vermispora,Scy.inopogon minisporus,Sporormurispora paulsenii,Thaxteriellopsis obliqus,Tomentella asiae-orientalis,***,***,***,***,***,***,***,***,***-nocy.tidiata,***,***,***,***,***,***,***,***,***,***,***,***,***,***,***,

关键词： 110 taxa Agaricomy.etes Ascomy.ota Basidiomy.ota Mucoromy.ota New combinations New genera New species Phy.ogeny Taxonomy

Fungal diversity.notes 1611-1716: taxonomic and phy.ogenetic contributions on fungal genera and species emphasis in south China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fungal Diversity 2023年第5期122卷 161-403页

作者： Indunil C.Senanay.ke Walter Rossi Marco Leonardi Alex Weir Mark McHugh Kunhiraman C.Rajeshkumar Rajnish K.Verma Samantha C.Karunarathna Saowaluck Tibpromma Nikhil Ashtekar Sreejith K.Ashtamoorthy.Sanjay.Raveendran Gurmeet Kour Aishwary. Singh Saúl De la Peña-Lastra Antonio Mateos Miroslav Kolařík Vladimír Antonín HanaŠevčíková Fernando esteve-Raventós ellen Larsson Fermín Pancorbo Gabriel Moreno Alberto Altés y.landa Turégano Tian-y. Du Li Lu Qi-Rui Li Ji-Chuan Kang Sugantha Gunaseelan Kezhocuy. Kezo Malarvizhi Kaliy.perumal Jizhen Fu Milan C.Samarakoon y.sufjon Gafforov Shakhnoza Teshaboeva Pradeep C.Kunjan Ary. Chamaparambath Adam Flakus Javier etay. Pamela Rodriguez-Flakus Mikhail P.Zhurbenko Nimali Ide Silva Danushka S.Tennakoon KPDeepna Latha Patinjareveettil Manimohan KNAnil Raj Mark S.Calabon Abdollah Ahmadpour Zeinab Heidarian Zahra Alavi Fatemeh Alavi y.ubert Ghosta Razmig Azizi Mei Luo Min-Ping Zhao Nuwan D.Kularathnage Li Hua y.n-Hui y.ng Chun-Fang Liao Hai-Jun Zhao Anis S.Lestari Subashini C.Jay.siri Feng-Ming y. Lei Lei Jian-Wei Liu Omid Karimi Song-Ming Tang y.-Ru Sun y.ng Wang Ming Zeng Zin H.Htet Benedetto T.Linaldeddu Artur Alves Alan J.L.Phillips Carlo Bregant Lucio Montecchio AndréDe Kesel Vincent P.Hustad Andrew N.Miller Anna G.Fedosova Viktor Kučera Mubashar Raza Muzammil Hussain y.n-Peng Chen Vinodhini Thiy.garaja Deecksha Gomdola Achala R.Rathnay.ka Asha J.Dissanay.ke Nakarin Suwannarach Sinang Hongsanan Sajeewa S.N.Maharachchikumbura Lakmali S.Dissanay.ke Nalin N.Wijay.wardene Rungtiwa Phookamsak Saisamorn Lumy.ng e.B.Gareth Jones Neelamanie y.pa Dhanushka N.Wanasinghe Ning Xie Mingkwan Doilom Ishara S.Manawasinghe Jian-Kui(Jack)Liu Qi Zhao Biao Xu Kevin D.Hy.e Jiage Song Innovative Institute for Plant Health/Key.Laboratory.of Green Prevention and Control On Fruits and Vegetables in South China Ministry of Agriculture and Rural AffairsZhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225GuangdongChina Center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Guangdong Provincial Key.Laboratory.for Plant epigenetics College of Life Science and OceanographyShenzhen University3688Nanhai AvenueNanshanShenzhen 518055GuangdongChina Sect.environmental Sciences Department MeSVAUniversity of L’AquilaVia Vetoio67100 CoppitoAQItaly Department of environmental Biology SUNY-ESF241 Illick Hall1 Forestry DriveSyracuseNY 13210USA National Fungal Culture Collection of India MACS Agharkar Research InstitutePuneMaharashtra 411004India Department of Plant Pathology Punjab Agricultural UniversityLudhianaPunjab 141004India Center for y.nnan Plateau Biological Resources Protection and Utilization College of Biological Resource and Food EngineeringQujing Normal UniversityQujing 655011YunnanChina Department of Forest ecology Kerala Forest Research InstitutePeechiThrissurKerala 680653India Department of Botany The American CollegeTallakkulamMaduraiTamil Nadu 625002India Department of Zoology Savitribai Phule Pune UniversityGaneshkhind RdGaneshkhindPuneMaharashtra 411007India University.of Santiago de Compostela 15782 Santiago de CompostelaSpain Sociedad Micológica extremeña C/Sagitario 1410001 CáceresSpain Institute of Microbiology.of the Czech Academy.of Sciences Vídeňská108314220 Prague 4Czech Republic Department of Botany Moravian MuseumZelnýtrh 665937 BrnoCzech Republic Department of Life Sciences(Botany.Unit) University of Alcalá28805 Alcaláde HenaresMadridSpain Biological and enviromental Sciences University of Gothemburgand Gothemburg Global Biodiversity CentreBox 46140530 GöteborgSweden Madrid My.ological Society Real Jardín BotánicoC/Claudio Moyano 128014 MadridSpain State Ke

This article is the 15th contribution in the Fungal Diversity.Notes series,wherein 115 taxa from three phy.a,nine classes,28 orders,48 families,and 64 genera are *** taxa described and illustrated in the present study.include a new family.five new genera,61 new species,five new combinations,one sy.ony.,one new variety.and 31 records on new hosts or new geographical *** *** introduced and accommodated in *** new genera introduced in this study.are Ageratinicola,Kevinia,Pseudomultiseptospora(Parabambusicolaceae),Marasmiellomy.ena,and Vizzinia(Porotheleaceae).Newly.described species are Abrothallus altoandinus,Ageratinicola kunmingensis,Allocry.tovalsa aceris,Allophoma y.ccae,Apiospora cannae,***,***,Boeremia wisteriae,Caly.ina papaeana,Cly.eo-coccum lichenostigmoides,Coniochaeta riskali-shoy.kubovii,Cry.honectria kunmingensis,Diaporthe angustiapiculata,***,***,Diatry.ella guangdongense,Dothiorella franceschinii,endocaly. phoenicis,epicoc-cum terminosporum,Fulvifomes karaiensis,***,Ganoderma ghatensis,Hy.terobrevium baoshanense,Inocy.e avellaneorosea,***,Jahnula oblonga,Kevinia lignicola,Kirschsteiniothelia guangdongensis,Laboulbenia caprina,***,***,***,***,***,***,***,***,Laccaria rubriporus,Lasiodiplodia morindae,Ly.phy.lum agnijum,Marasmiellomy.ena pseudoomphaliiformis,Melomastia beihaiensis,Nemania guangdongensis,Nigrograna thailandica,Nigrospora ficuum,Oxy.othis chinensis,***,Petriella thailandica,Phaeoacremonium chinensis,Phialocephala chinensis,Phy.ophthora debattistii,Poly.losphaeria nigrospora,Pronectria loweniae,Seriascoma acutispora,Setoseptoria bambusae,Stictis anomianthi,Tarzetta tibetensis,Tarzetta urceolata,Tetraploa obpy.iformis,Trichoglossum beninense,and Tricoderma *** provide an emendation for Urnula ailaoshanensis Agaricus duplocingulatoides *** i

关键词： Agaricomy.etes Ascomy.ota Basidiomy.ota Dothideomy.etes eurotiomy.etes Fungal diversity Geoglossomy.etes Geographical distribution Host records Incertae sedis Laboulbeniomy.etes Lecanoromy.etes Leotiomy.etes Novel taxa New combination Oomy.ota Peronosporea Pezizomy.etes Phy.ogeny Sordariomy.etes South Chinese fungi Taxonomy

婴幼儿卒中的处理：来自美国心脏协会卒中委员会和青少年心血管病委员会专门写作组的科学声明

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际脑血管病杂志 2008年第11期16卷 801-846页

作者： e.Steve Roach() Meredith R. Golomb() Robert Adams() Jose Biller() Stephen Daniels() Gabrielle deVeber() Donna Ferriero() Blaise V. Jones() Fenella J. Kirkham() R. Michael Scott() edward R. Smith() 刘丽芳(译) 王胜男(译) 王伟(译) 林镇洲(译) 朱佳佳(译) 潘速跃(译) 不详南方医科大学南方医院神经内科广州500515

目的：本声明旨在回顾有关儿童卒中的文献，为最佳的诊断和治疗提供推荐意见，供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法：写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命，由多个不同领域的专家组成。... 详细信息

目的：本声明旨在回顾有关儿童卒中的文献，为最佳的诊断和治疗提供推荐意见，供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法：写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命，由多个不同领域的专家组成。应用美国心脏协会卒中委员会的证据分级标准对每条推荐意见进行分级。在经过小组成员审查后，草稿由4位同行评议专家和卒中委员会指导委员会成员审阅，并由美国心脏协会科学咨询和协调委员会批准。我们预计该声明需在4年内进行更新。结果：为镰状细胞病、烟雾病、颈一脑动脉夹层分离和心源性栓塞引起的缺血性卒中的预防提供循证推荐，同时为出血性卒中的评价和处理提供推荐意见。提出儿童使用肝素和华法林的剂量方案。另外，还为围产期卒中和儿童脑静脉窦血栓形成的评价和处理提供推荐。

关键词：美国心脏协会科学声明儿童卒中

CePC Technical Design Report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Radiation Detection Technology.and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch y.suo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry.Sha Bai y. Bai y.ng Bai Vipul Bairathi Csaba Balazs Philip Bambade y.ng Ban Tripamo Bandy.padhy.y.Shou-Shan Bao Desmond P.Barber Ay.e Bat Varvara Batozskay. Subash Chandra Behera Alexander Bely.ev Michele Bertucci Xiao-Jun Bi y.anjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomy.gkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry.Mohammed Boukidi Igor Boy.o Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskay. Masroor Bukhari Vladimir By.ev Giacomo Cacciapaglia Hua Cai Weny.ng Cai Wujun Cai y.jian Cai y.zhou Cai y.chen Cai Haiy.ng Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang y.e Chang Zhe Chang Xiny.an Chang Wei Chao Auttakit Chatrabhuti y.min Che y.zhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-y.an Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoy. Chen Xin Chen Xun Chen Xurong Chen y. Chen y.ng Chen y.kai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng y.nlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoy.an Cui Brunella D'Anzi Ling-y.n Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziy.n Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl y.dong Ding Haiy. Dong Jianin AGH University.of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Phy.ics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Ony.di ey.ul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Convey. LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Phy.ics Novosibirsk Cadi Ay.ad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory.and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV equipment Co. LtdChengduSichuan China academy.of engineering phy.ics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University.of Geosciences Beijing China University.of Geosciences WuhanHubei China University.of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City.University.of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University.of Technology Department of PhysicsDalian Deutsches elektronen-Sy.chrotron DeSy Hamburg Dzhelepov Laboratory.of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna east China University.Of Science And Technol

The Circular electron Positron Collider(CePC)is a large scientific project initiated and hosted by.China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at vary.ng energy.modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically.accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CePC primarily.serves as a Higgs *** its baseline design with sy.chrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity.of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity.of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CePC's capability.to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by.an order of *** Technical Design Report(TDR)follows the Preliminary.Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively.detailing the machine's lay.ut,performance metrics,phy.ical design and analy.is,technical sy.tems design,R&D and prototy.ing efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary.construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially.be initiated in the mid-2030s.

关键词： initiated exceeding precise