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Food science and Human Wellness 2023年第2期12卷 520-527页

作者： Adetiya Rachman Margaret Abrennan James Morton Damir Torrico charles s.brennan Department of Wine Food and Molecular BiosciencesLincoln UniversityChristchurch 7647New Zealand Riddet Research Institute Palmerston North 4442New Zealand Indonesia Institute for Agricultural Research and Development Jakarta 12540Indonesia

soy protein isolate and egg white protein were added to cassava-banana gluten-free pasta and the effects on the nutritional quality,digestibility properties,protein digestibility corrected amino acid(PDCAA),and sensory acceptance of the pasta was ***-cassava composite flour(75:25)was blended with soy protein isolate or egg white protein at the following rates:0,5,10,and 15 g/100 g *** pasta samples were analysed for total phenolic content(TPC),antioxidant activity,amino acid profiles,protein content,starch digestibility,protein digestibility and protein digestibility corrected amino acid score(PDCAAs).Addition of both proteins decreased starch digestibility,increased protein digestibility,improved the balance of the amino acid profile,and PDCAAs whereas only soy protein isolate enhanced the TPC and antioxidant capacity of the banana-cassava *** egg white protein-fortified banana-cassava pasta had better customer acceptance and purchase intent than soy protein isolate inclusion.

关键词： Banana flour Cassava flour Gluten-free pasta Digestibility properties Amino acid sensory evaluation

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Function and dysfunction of GEMIN5:understanding a novel neurodevelopmental disorder

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Neural Regeneration Research 2024年第11期19卷 2377-2386页

作者： charles H.Nelson Udai B.Pandey Department of Pediatrics Division of Child NeurologyChildren’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA Children’s Neuroscience Institute Children’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA

The recent identification of a neurodevelopmental disorder with cerebellar atrophy and motor dysfunction(NEDCAM)has resulted in an increased interest in GEMIN5,a multifunction RNA-binding *** the largest member of the survival motor neuron complex,GEMIN5 plays a key role in the biogenesis of small nuclear ribonucleoproteins while also exhibiting translational regulatory functions as an independent *** many questions remain regarding both the pathogenesis and pathophysiology of this new disorder,considerable progress has been made in the brief time since its *** this review,we examine GEMIN5 within the context of NEDCAM,focusing on the structure,function,and expression of the protein specifically in regard to the disorder ***,we explore the current animal models of NEDCAM,as well as potential molecular pathways for treatment and future directions of *** review provides a comprehensive overview of recent advances in our understanding of this unique member of the survival motor neuron complex.

关键词： cerebellar atrophy GEMIN5 neurodevelopmental disorder neurological disease sMN complex

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Governance in the exploration of global and regional determinants of ICT development

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International Journal of Innovation studies 2024年第2期8卷 132-153页

作者： charles s.saba simplice A.Asongu Nicholas Ngepah Yolande E.Ngoungou school of Economics College of Business and EconomicsUniversity of JohannesburgJohannesburgSouth Africa Department of Econornic&Data science New Uzbekistan University54 Mustaili AvenueTashkent100007Uzbekistan University of Yaounde 2 SoaCameroon

The present study assesses how governance affects information and communication technology(IcT)at the global level contingent on macroeconomic policy factors such as trade,foreign direct investment(FDI),manufacturing value added,and agricultural value *** study focuses on 183 countries from 2003 to 2021,and the empirical evidence is based on the generalized method of moments(GMM).The following main findings are *** the full sample,governance unconditionally promotes ICT development,while trade openness(industrial added value)moderates governance to promote(dampen)ICT *** sub-saharan Africa,only trade openness effectively moderates governance to induce an overall positive effect on ICT,while in the Middle East and North Africa(MENA)region,all policy variables moderate governance for an overall positive incidence on ICT sector *** findings for the MENA region are confirmed in the Europe and Central Asia(ECA)region,with the exception of the moderating role of industrial added value,which engenders an overall negative *** the East and south Asia and the Pacific(EsAP)countries,one overall positive incidence is apparent in the role of trade openness,while net negative effects are established from the moderating roles of industrial added value and agricultural added *** the American sub-sample,a positive(negative)net effect is apparent from the role of industrial added value(trade)in moderating the incidence of gover-nance on ICT sector ***,policy implications are discussed.

关键词： ICT Governance Trade FDI Industry Agriculture

New evidence for the epigenetic regulation of skeletal stem cells

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science Bulletin 2024年第13期69卷 2004-2006页

作者： Liming Zhao Jun Xiao charles K.F.Chan Institute for stem Cell Biology and Regenerative Medicine Stanford University School of MedicineStanford CA 94305USA Department of surgery Division of Plastic and Reconstructive SurgeryStanford University School of MedicineStanford CA 94305USA Department of Orthopaedic surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

skeletal stem cells(ssCs)are crucial for skeletal development and regeneration,yet the epigenetic regulation of these cells remains poorly *** studies have delineated the epigenetic landscape across the developmental trajectory of ssCs,highlighting the involvement of Ptip in regulating ssC *** skeletal system undergoes dynamic remodeling throughout *** stem cells(ssCs),residing within the skeleton and lineage-restricted,serve as a cellular reserve to foster development and maintain skeletal *** categorized within the broader mesenchymal stromal/stem cells(MsCs).

关键词： skeletal involvement maintain

William Morris,Establishing the Foundation for the Advancement of TCM in the Us

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Chinese Medicine and Culture 2024年第1期7卷 29-40页

作者： Ioannis solos charles Buck William Morris saint George Clinic and Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom AOMA Graduate school of Integrative Medicine Austin 78745the United States of America

The interview was conducted on March 2nd, 2023 by Ioannis solos and charles Buck. William Morris has sustained practice since 1980. He has served on the California, Texas and Massachusetts Professional Associations, as well as the National Association. He has tendered 20 years of service to the field through academic medicine, earning a master’s degree in medical education to assist in developing Chinese medical doctoral programs and institutional review boards. He earned an OM.D. in 1988, a DAOM in 2002, and a Ph.D. focused on pulse diagnosis as clinical epistemology in 2009. He has published five books, including TCM Case studies Dermatology, Li shi-zhen Pulse studies: An Illustrated Guide, Neoclassical Pulse Diagnosis, Cycles in Medical Astrology, and Transformation: Treating Trauma with Acupuncture and Herbs.

关键词： Acupuncture sustained diagnosis

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食品工程研究生导师团队培养模式研究

安徽农业科学 2024年第8期52卷 280-282页

作者：王姝杰杨周昊 Charles.brennan 曹建新程桂广陈海燕覃宇悦昆明理工大学食品科学与工程学院云南昆明650550 school of science Royal Melbourne Institute of Technology UniversityMelbourne 3000Australia

国内外发展趋势表明,构建研究生导师团队培养模式将成为高校研究生培养的主流。本文以昆明理工大学食品科学与工程学院食品功能因子研究与利用团队为例,阐述了传统单一导师培养模式存在的弊端,提出了研究生导师团队建设以及研究生培养... 详细信息

国内外发展趋势表明,构建研究生导师团队培养模式将成为高校研究生培养的主流。本文以昆明理工大学食品科学与工程学院食品功能因子研究与利用团队为例,阐述了传统单一导师培养模式存在的弊端,提出了研究生导师团队建设以及研究生培养的具体实践方案,以期为食品工程硕士研究生的培养提供借鉴。

关键词：食品工程导师团队培养模式素质

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A Tale of Two Visits

ChinAfrica 2024年第8期16卷 14-15页

作者： charles ONUNAIJU Centre for China studies AbujaNigeria

Chinese Foreign Minister Wang Yi’s visit to Africa focuses on addressing practical issues,while Us adapts to a changing *** 13 to 18 January,Chinese Foreign Minister Wang Yi visited four African countries in keeping with the more than three decades of tradition where Chinese foreign ministers start their yearly overseas visits with a trip to ***,while these visits have become a routine for China’s diplomatic practice,they are not an empty *** represent a tradition of China-Africa pragmatic cooperation defined by mutual consultations and tangible *** is neither opportunistic nor paternalistic,but rather engagement in the specific issues of concern for the particular country in relation to bilateral cooperation with China and the overall framework of the broader and comprehensive China-Africa cooperation.

关键词： mutual Africa cooperation

A Democracy That Works Western democracies have failed to address people’s livelihood concerns while the Chinese practice has made notable achievements

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ChinAfrica 2024年第5期16卷 16-17页

作者： charles ONUNAIJU Centre for China studies AbujaNigeria

More than 200 scholars,researchers,former government o!cials and party leaders from over 50 countries gathered in the sprawling building of the Chinese Academy of History in Beijing on 20 March for the third International Forum on Democracy:The shared Human *** forum debated the concept of democracy,its trajectories and prospects,and,more importantly,how it can be made to work and deliver tangible results for di"erent countries.

关键词： Democracy gathered debate

An Analysis of Liberia’s Vulnerability to Climate Change in the Context of Least Developed Countries (LDCs): A Review

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American Journal of Climate Change 2024年第2期13卷 230-250页

作者： charles Flomo Togbah state Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and Engineering Tongji University Shanghai China UNEP-Tongji Institute of Environment for sustainable Development Shanghai China

Climate change is an alarming global challenge, particularly affecting the least developed countries (LDCs) including Liberia. These countries, located in regions prone to unpredictable temperature and precipitation changes, are facing significant challenges, particularly in climate-sensitive sectors such as mining and agriculture. LDCs need more resilience to adverse climate shocks but have limited capacity for adaptation compared to other developed and developing nations. This paper examines Liberia’s susceptibility to climate change as a least developed country, focusing on its exposure, sensitivity, and adaptive capacity. It provides an overview of LDCs and outlines the global distribution of carbon dioxide emissions. The paper also evaluates specific challenges that amplify Liberia’s vulnerability and constrain sustainable adaptation, providing insight into climate change’s existing and potential effects. The paper emphasizes the urgency of addressing climate impacts on Liberia and calls for concerted local and international efforts for effective and sustainable mitigation efforts. It provides recommendations for policy decisions and calls for further research on climate change mitigation and adaptation.

关键词： Least Developed Countries Liberia Climate Change Vulnerability Poverty Hunger Disease Research and Development (R&D) Adaptation

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骨骼干细胞表观遗传调控的新证据（英文）

science Bulletin 2024年第13期 2004-2006页

作者：赵黎明肖骏 charles K.F.Chan Institute for stem Cell Biology and Regenerative Medicine Stanford University School of Medicine Department of surgery Division of Plastic and Reconstructive Surgery Stanford University School of Medicine Department of Orthopaedic surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

skeletal stem cells (ssCs) are crucial for skeletal development and regeneration, yet the epigenetic regulation of these cells remains poorly understood. Recent studies have delineated the epigenetic landscape across the developmental trajectory of ssCs,highlighting the involvement of Ptip in regulating ssC *** skeletal system undergoes dynamic remodeling throughout life. skeletal stem cells (ssCs), residing within the skeleton and lineage-restricted, serve as a cellular reserve to foster development and maintain skeletal homeostasis. Historically categorized within the broader mesenchymal stromal/stem cells (MsCs), ssCs have been differentiated due to MsCs’ recognized heterogeneity, which has generated inconsistencies and controversies in the field [1].

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