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Journal of Wuhan University of Technology(Materials Science) 2013年第5期28卷 934-937页

作者：何雄君 YANG Jingnan charles E Bakis School of Transportation Wuhan University of Technology Department of Engineering Science and Mechanics Pennsylvania State UniversityUniversity Park

To investigate the effect of different environmental conditions of GfRP bars in concrete beams with work cracks subjected to sustained loads, the beams were exposed in indoor, freeze/thaw cycles and immersed in alkaline solution at elevated temperature. The bars were carefully extracted from the beams and tested in order to evaluate residual tensile properties. The results show that the tensile strength decreased significantly in the highly aggressive conditions but not in the natural conditions. The effect of GfRP bars casting in concrete beams demonstrated approximately 2.5% decrease of tensile strength caused by pore water environment in concrete beams on basis of those of the original bars. The effect of sustained loading plus work cracks demonstrated about 10.5% tensile strength decrease on basis of those of the bars only casted in concrete beams. The effect of environments under sustained loading plus work cracks demonstrated about 17% tensile strength decrease caused by a saturated solution of Ca（OH）2 and 60-2 ℃ tap water （pH=12-13） and about 8% tensile strength decrease caused by freezing and thawing cycle （f/T）, both on basis of those of the bars of the indoor beams only under sustained loading plus work cracks. The results demonstrate the effects of the tensile strengths under different environmental conditions of GfRP bars in concrete beams with work cracks subjected to sustained loads.

关键词： GfRP bars concrete beams working cracks sustained loading and severe environments tensile strength

WEAK ERROR ESTIMATES fOR TRAJECTORIES Of SPDEs UNDER SPECTRAL GALERKIN DISCRETIZATION

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Journal of Computational Mathematics 2018年第2期36卷 159-182页

作者： charles-Edouard Brehier Martin Hairer Andrew M. Stuart Univ Lyon CNRS Universite Claude Bernard Lyon 1 UMR5208 Institut Camille Jordan F-69622 Villeurbanne France Department of Mathematics Imperial College London London SW7 2AZ UK Computing and Mathematical Sciences California Institute of Technology 1200 E. California Blvd. MC 305-16 Pasadena CA 91125 USA

We consider stochastic semi-linear evolution equations which are driven by additive, spatially correlated, Wiener noise, and in particular consider problems of heat equation （analytic semigroup） and damped-driven wave equations （bounded semigroup） type. We discretize these equations by means of a spectral Galerkin projection, and we study the approximation of the probability distribution of the trajectories： test functions are regular, but depend on the values of the process on the interval [0, T]. We introduce a new approach in the context of quantative weak error analysis for discretization of SPDEs. The weak error is formulated using a deterministic function （It6 map） of the stochastic convolution found when the nonlinear term is dropped. The regularity properties of the It6 map are exploited, and in particular second-order Taylor expansions employed, to transfer the error from spectral approximation of the stochastic convolution into the weak error of interest. We prove that the weak rate of convergence is twice the strong rate of convergence in two situations. first, we assume that the covariance operator commutes with the generator of the semigroup： the first order term in the weak error expansion cancels out thanks to an independence property. Second, we remove the commuting assumption, and extend the previous result, thanks to the analysis of a new error term depending on a commutator.

关键词： Stochastic Partial Differential Equations Weak approximation Spectral Galerkin discretization

Drugs, Behavior, and Modern Society 2nd ed.

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forage and breed effects on behavior and temperament of pregnant beef heifers

1998年

作者： Levinthal, charles f.

ISBN: (纸本)9780205277032

This text examines the impact of drug-taking behavior on our society and our daily lives. The use and abuse of a wide range of licit and illicit drugs are discussed from historical, biological, psychological, and sociological perspectives. for undergraduate Drugs and Behavior courses . In today's world, drugs and their use present a social paradox, combining the potential for good and for bad. As a society and as individuals, we can be the beneficiaries of drugs or their victims. Drugs, Behavior, and Modern Society, Sixth Edition features a comprehensive review of psychoactive drugs, and is notable for the attention it gives to two aspects of drug-taking behavior that have been underreported in other texts: steroid abuse and inhalant abuse.

关键词： Drugs.

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Journal of Animal Science and Biotechnology 2013年第3期4卷 165-169页

作者： Angela R Mays Michael L Looper Benjamin C Williamson Kenneth P Coffey Wayne K Coblentz Glen E Aiken charles f Rosenkrans Jr Department of Animal Science University of ArkansasFayetteville AR 72701 USA Department of Agricultural Sciences Morehead StateUniversity327 Reed Hall Morehead KY 40351 USA USDA-ARS US Dairy Forage Research CenterMarshfield WI 54449 USA USDA-ARS Forage Animal Production Research UnitLexingtonKY 40546 USA

Background： Integration of behavioral observations with traditional selection schemes may lead to enhanced animal well-being and more profitable forage-based cattle production ***-influenced（BR;n = 64） and Gelbvieh × Angus（GA;n = 64） heifers consumed either toxic endophyte-infected tall fescue（E＋） or one of two nontoxic endophyte-infected tall fescue（NT） cultivars during two *** were weighed at midpoint and termination of *** behavior（grazing,resting in the shade,lying,or standing without grazing） was recorded（n = 13 visual observations per yr in June and July） for each *** yr 2,exit velocity（EV） and serum prolactin（PRL） were ***： Grazing behavior was influenced（P 0.05） by an interaction between fescue cultivar and breed *** × Angus heifers assigned to E＋ pastures had the lowest percentage of animals grazing and the largest percentage of animals resting in the ***-influenced heifers had faster EV（P 0.001） than GA heifers（0.52 vs.0.74 ± 0.04 s/m,respectively）.Body weight（BW） was affected（P 0.01） by an interaction of tall fescue cultivar and d,and an interaction of tall fescue cultivar and breed *** grazing NT pastures were heavier（P 0.01） than heifers grazing E＋ pastures at midpoint and *** × Angus heifers grazing NT pastures were heavier（P 0.01） than GA and BR heifers grazing E＋ and BR heifers grazing NT *** interaction of forage cultivar and breed type occurred on serum PRL（P 0.01）.Conclusion： Collectively fescue cultivar,EV,and concentrations of serum PRL were associated with grazing *** grazing NT pastures were observed to be grazing more than heifers assigned to E＋ pastures,regardless of breed type,which may have contributed to changes in BW and average daily gain（ADG） in *** of behavioral observations along with traditional selection schemes may lead to enhanced animal well-being and more profitable forage-based cattle prod

关键词： Cattle Endophyte-infected tall fescue Grazing behavior Prolactin Temperament

Parastomal hernia repair

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Plastic and Aesthetic Research 2022年第1期9卷 402-412页

作者： Jeffrey Michael Smith Sahil K.Kapur Alexander f.Mericli Donald P.Baumann charles E.Butler Department of Plastic Surgery The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Surgery Division of Plastic SurgeryThe University of Texas Medical BranchGalvestonTX 77555USA

Despite significant advances in abdominal wall reconstruction,parastomal hernias remain a complex problem,with a high risk of recurrence following *** a number of surgical hernia repair techniques have been proposed,there is no consensus on optimal *** clinical variables must be considered when developing a comprehensive repair plan that minimizes the likelihood of hernia recurrence and surgical site *** this review,we describe the incidence of parastomal hernias and discuss pertinent risk factors,medical history findings,physical examination findings,supplementary diagnostic modalities,parastomal hernia classification systems,surgical indications,and repair *** consideration is given to the discussion of mesh reinforcement,including available biomaterials,anatomic plane selection,and the extent of mesh *** open repairs are the primary focus of this article,minimally invasive laparoscopic and robotic approaches are also briefly *** is our hope that the provided surgical outcome data will help guide surgical management and optimize outcomes for affected patients.

关键词： Abdominal wall reconstruction parastomal hernia stoma biologic mesh synthetic mesh polypropylene acellular dermal matrix

Molecular mechanisms of liver carcinogenesis related to metabolic syndrome

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Hepatoma Research 2022年第1期8卷 22-34页

作者： Claudia Campani Jean-charles Nault Team of functional Genomics of Solid Tumors Centre de Recherche des CordeliersSorbonne UniversitéInsermUniversitéde ParisParis F-75006France Equipe labellisée Ligue Nationale Contre le Cancer Labex OncoImmunologyParis F-75006France Department of Experimental and Clinical Medicine University of FlorenceFlorence 50139Italy Service d’hépatologie Hôpital AvicenneHôpitaux Universitaires Paris-Seine-Saint-DenisAssistance-Publique Hôpitaux de ParisBobigny 93000France Unitéde formation et de Recherche SantéMédecine et Biologie Humaine UniversitéParis 13Communautéd’Universités et Etablissements Sorbonne Paris CitéBobigny 93000France

Global prevalence of non-alcoholic fatty liver disease(NAfLD)and of NAfLD-hepatocellular carcinoma(HCC)is estimated to grow in the next *** burden of NAfLD and the evidence that NAfLD-HCC arises also in noncirrhotic patients,explain the urgent need of a better characterization of the molecular mechanisms involved in NAfLD *** and diabetes cause a chronic inflammatory state which favors changes in serum cytokines and adipokines,an increase in oxidative stress,DNA damage,and the activation of multiple signaling pathways involved in cell ***,a role in promoting NAfLD-HCC has been highlighted in the innate and adaptive immune system,dysbiosis,and alterations in bile acids *** dietary,genetic,or combined mouse models have been used to study nonalcoholic steatohepatitis(NASH)development and its progression to HCC,but models that fully recapitulate the biological and prognostic features of human NASH are still *** humans,four single nucleotide polymorphisms(PNPLA3,TM6Sf2,GCKR,and MBOAT7)have been linked to the development of both NASH and HCC in cirrhotic and non-cirrhotic patients,whereas HSD17B13 polymorphism has a protective *** addition,higher rates of somatic ACVR2A mutations and a novel mutational signature have been recently discovered in NASH-HCC *** knowledge of the molecular pathogenesis of NAfLD-HCC will be helpful to personalized screening programs and allow for primary and secondary chemopreventive treatments for NAfLD patients who are more likely to progress to HCC.

关键词： Hepatocellular carcinoma mouse model genetic predisposition cirrhosis non-alcoholic fatty liver disease immune system

Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel： self-reported and autonomic improvements

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Military Medical Research 2018年第1期5卷 1-12页

作者： Catherine L.Tegeler Lee Gerdes Hossam A.Shaltout Jared f.Cook Sean L.Simpson Sung W.Lee charles H.Tegeler Department of Neurology Wake Forest School of Medicine Medical Center Boulevard Winston-Salem NC 27157 USA Brain State Technologies LLC 15150 North Hayden Road Scottsdale AZ 85260USA Hypertension and Vascular Research Center Wake Forest School of Medicine Medical Center Boulevard Winston-Salem NC 27157USA Department of Biostatistical Sciences Wake Forest School of Medicine Medical Center Boulevard Winston-Salem NC 27157 USA

Background:Military-related post-traumatic stress(PTS)is associated with numerous symptom clusters and diminished autonomic cardiovascular ***,relational,resonance-based,electroencephalic mirroringis a noninvasive,closed-loop,allostatic,acoustic stimulation neurotechnology that produces realtime translation of dominant brain frequencies into audible tones of variable pitch and timing to support the autocalibration of neural *** report clinical,autonomic,and functional effects after the use offor symptoms of military-related ***:Eighteen service members or recent veterans(15 active-duty,3 veterans,most from special operations,1 female),with a mean age of 40.9(SD=6.9)years and symptoms of PTS lasting from 1 to 25 years,undertook19.5(SD=1.1)sessions over 12 *** for symptoms of PTS(Posttraumatic Stress Disorder Checklist–Military version,PCL-M),insomnia(Insomnia Severity Index,ISI),depression(Center for Epidemiologic Studies Depression Scale,CES-D),and anxiety(Generalized Anxiety Disorder 7-item scale,GAD-7)were collected before(Visit1,V1),immediately after(Visit2,V2),and at 1 month(Visit3,V3),3(Visit4,V4),and 6(Visit5,V5)months after intervention *** measures only taken at V1 and V2 included blood pressure and heart rate recordings to analyze heart rate variability(HRV)and baroreflex sensitivity(BRS),functional performance(reaction and grip strength)testing,blood and saliva for biomarkers of stress and inflammation,and blood for epigenetic *** t-tests,Wilcoxon signed-rank tests,and a repeated-measures ANOVA were ***:Clinically relevant,significant reductions in all symptom scores were observed at V2,with durability through *** were significant improvements in multiple measures of HRV and BRS[Standard deviation of the normal beat to normal beat interval(SDNN),root mean square of the successive differences(rMSSD),high frequency(Hf),low frequency(Lf),and total power,Hf alpha,

关键词： Neurotechnology Allostasis Autonomic Heart rate variability Baroreflex sensitivity Closed-loop Acoustic stimulation Military Post-traumatic stress disorder HIRREM

Structure of [Co(im)6]Sif6：Short Hydrogen Bonds Involving Sif62- Ions

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Chinese Journal of Structural Chemistry 2017年第6期36卷 965-970页

作者： NAZIR Sadia ARIf Muhammad RASHID Muhammad Abid WHITWOOD Adrian charles Department of Chemistry Govt. College Women University Faisalabad 3800 Pakistan Institute of Chemical Sciences Bahhauddin Zakariya University Multan 60800 Pakistan Department of Chemistry University of Agriculture Faisalabad 38040 Pakistan Department of Chemistry University of York Heslington York YO10 5DD UK

A new complex C（18）H（24）Cof6N（12）Si has been synthesized by the reaction of cobalt（II） fluoride tetrahydrate with imidazole in a glass vessel. Sif62-was generated by in situ reaction of fluoride on silica. This complex has been characterized by different techniques such as elemental analysis, IR studies, magnetic measurements, electronic absorption measurements and single-crystal X-ray structure determination. The crystals are hexagonal in the R-3 space group, with a = 13.225（6）, b = 13.225（6）, c = 12.517（11） A, and g = 120°. In complex [Co（im）6]Sif6, the cobalt atom is six-coordinated to adopt a regular octahedral geometry and the Sif62-ion acts as the counter anion. The crystal displays a network structure and Sif62- bridging hexagram formation by N-（39）···f-Si interactions between imdazole and Sif62-. Sif62-plays an important role in assembling the supramolecular aggregates.

关键词： anion binding imidazole Sif62- hydrogen bonds transitionmetal fluoride complexes

An Ensemble-Based Hotel Reviews System Using Naive Bayes Classifier

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Computer Modeling in Engineering & Sciences 2023年第10期137卷 131-154页

作者： Joseph Bamidele Awotunde Sanjay Misra Vikash Katta Oluwafemi charles Adebayo Department of Computer Science Faculty of Information and Communication SciencesUniversity of IlorinIlorin240003Nigeria Department of Computer Science and Communication Otfold University CollegeHaldenNorway

The task of classifying opinions conveyed in any form of text online is referred to as sentiment *** emergence of social media usage and its spread has given room for sentiment analysis in our daily *** media applications and websites have become the foremost spring of data recycled for reviews for sentimentality in various *** subject matter can be encountered on social media platforms,such as movie product reviews,consumer opinions,and testimonies,among others,which can be used for sentiment *** rapid uncovering of these web contents contains divergence of many benefits like profit-making,which is one of the most vital of them *** to a recent study,81%of consumers conduct online research prior to making a *** the reviews available online are too huge and numerous for human brains to process and ***,machine learning classifiers are one of the prominent tools used to classify sentiment in order to get valuable information for use in companies like hotels,game companies,and so *** the sentiments of people towards different commodities helps to improve the services for contextual promotions,referral systems,and market ***,this study proposes a sentiment-based framework detection to enable the rapid uncovering of opinionated contents of hotel reviews.A Naive Bayes classifier was used to process and analyze the dataset for the detection of the polarity of the *** dataset from Datafiniti’s Business Database obtained from Kaggle was used for the experiments in this *** performance evaluation of the model shows a test accuracy of 96.08%,an f1-score of 96.00%,a precision of 96.00%,and a recall of 96.00%.The results were compared with state-of-the-art classifiers and showed a promising performance andmuch better in terms of performancemetrics.

关键词： Sentiment analysis hotel reviews Naive Bayes algorithm consumer opinions web 2.0 machine learning

Mutations of the aurora kinase C gene causing macrozoospermia are the most frequent genetic cause of male infertility in Algerian men

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Asian Journal of Andrology 2015年第1期17卷 68-73,I0008页

作者： Leyla Ounis Abdelali Zoghmar charles Coutton Leila Rouabah Maroua Hachemil Delphine Martinez Guillaume Martinez Ines Bellil Douadi Khelifi Christophe Arnoult Julien faure Sebti Benbouhedja Abdelkader Rouabah Pierre f Ray Laboratoire de Biologie Moleculaire et Cellulaire Faculte des Sciences de la Nature et de la Vie Universite Constantine I Algerie Clinique Ibn Rochd Centre de Medecine de la Reproduction Constantine Algerie Universite Grenoble Alpes Grenoble France Equipe Genetique Epigenetique et Therapies de I'lnfertilitE CNRS AGIM Grenoble France Laboratoire de GEnetique Chromosomique CHU Grenoble Grenoble France Laboratoire de Biochimie et Genetique Moleculaire CHU Grenoble Grenoble France Equipe Muscle et Pathologies INSERM U836 Grenoble Institut des Neurosciences Grenoble France.

Klinefelter syndrome and Y-chromosomal microdeletion analyses were once the only two genetic tests offered to infertile men. Analyses of aurora kinase C （AURKCj and DPY19L2 are now recommended for patients presenting macrozoospermia and globozoospermia, respectively, two rare forms of teratozoospermia particularly frequent among North African men. We carried out genetic analyses on Algerian patients, to evaluate the prevalence of these syndromes in this population and to compare it with the expected frequency of Klinefelter syndrome and Y-microdeletions. We carried out a retrospective study on 599 consecutive patients consulting for couple infertility at the assisted reproduction unit of the Ibn Rochd Clinique, Constantine, Algeria. Abnormal sperm parameters were observed in 404 men. fourteen and seven men had typical macrozoospermia and globozoospermia profiles, respectively. Molecular diagnosis was carried out for these patients, for the AURKC and DPY19L2 genes. Eleven men with macrozoospermia had a homozygous AURKC mutation （79%）, corresponding to 2.7% of all patients with abnormal spermograms. All the men with globozoospermia studied （n = 5）, corresponding to 1.2% of all infertile men, presented a homozygous DPY19L2deletion. By comparison, we would expect 1.6% of the patients in this cohort to have Klinefelter syndrome and 0.23% to have Y-microdeletion. Our findings thus indicate that AURKCmutations are more frequent than Klinefelter syndrome and constitute the leading genetic cause of infertility in North African men. furthermore, we estimate that AURKCand DPY19L2 molecular defects are 10 and 5 times more frequent, respectively, than Y-microdeletions.

关键词： aurora kinase C DPY19L2 globozoospermia intracytoplasmic sperm injection infertility macrozoospermia