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Indications,limitations and maneuvers to enable extended hepatectomy:Current trends

World Journal of Gastroenterology 2014年第24期20卷 7887-7893页

作者： Dimitrios Dimitroulis Petros Tsaparas Serena Valsami Dimitrios Mantas Eleftherios Spartalis charalampos markakis Gregory Kouraklis Second Department of Propedeutic Surgery Athens University Medical School"Laiko" Hospital11527 AthensGreece Blood Transfusion Department Athens University Medical SchoolAreteion Hospital11527 AthensGreece

The liver is a solid organ with a wide variety of primary benign or malignant tumors as well as metastatic *** resection of these tumors remains the only curative *** limitations,however,do not allow the performance of these *** review evaluates the indications and limitations regarding these extended hepatic resections,as well as describing all the manipulations that increase the candidates for such operations.A thorough review of the literature was performed in order to define indications for extended hepatectomy,as well as to present all methods that contribute to increasing the volume of the future remnant *** role of portal vein ligation,portal vein embolization,two-stage hepatectomy,and in situ liver transection are evaluated in the setting of indications and *** hepatectomies are a necessity due to oncological *** methods developed in order to increase the volume of the remnant liver are safe and *** situ liver transection is a novel and revolutionary two-step procedure for extended hepatic *** clinical studies are required to estimate long-term results and the oncological basis of this technique.

关键词： Extended hepatectomy Portal vein ligation Remnant liver volume

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Role of platelet-rich plasma in ischemic heart disease: An update on the latest evidence

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World Journal of Cardiology 2015年第10期7卷 665-670页

作者： Eleftherios Spartalis Periklis Tomos Demetrios Moris Antonios Athanasiou charalampos markakis Michael D Spartalis Theodore Troupis Dimitrios Dimitroulis Despina Perrea Second Department of Propedeutic Surgery Athens University Medical School "Laiko" Hospital Department of Cardiology Onassis Cardiac Surgery Center Department of Anatomy Medical School University of Athens Laboratory of Experimental Surgery and Surgical Research "N.S.Christeas" Medical School University of Athens

Myocardial infarction is the most common cause of congestive heart failure. Novel strategies such as directly reprogramming cardiac fibroblasts into cardiomyocytes are an exciting area of investigation for repair of injured myocardial tissue. The ultimate goal is to rebuild functional myocardium by transplanting exogenous stem cells or by activating native stem cells to induce endogenous repair. Cell-based myocardial restoration, however, has not penetrated broad clinical practice yet. Plateletrich plasma, an autologous fractionation of whole blood containing high concentrations of growth factors, has been shown to safely and effectively enhance healing and angiogenesis primarily by reparative cell signaling. In this review, we collected all recent advances in novel therapies as well as experimental evidence demonstrating the role of platelet-rich plasma in ischemic heart disease, focusing on aspects that might be important for future successful clinical application.

关键词： Platelet-rich plasma Ischemic heart disease Myocar

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