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Flexible 2 × 2 multiple access visible light communication system based on an integrated parallel GaN/InGaN micro-photodetector array module

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Photonics Research 2024年第4期12卷 793-803页

作者： ZENGYI XU XIANHAO LIN ZHITENG luo QIANYING LIN JIANLI ZHANG GUANGXU WANG XIAOLAN WANG FENGYI JIANG ZIWEI LI JIANYANG SHI JUNWEN ZHANG chao SHEN NAN CHI Key Laboratory for Information Science of Electromagnetic Waves(MoE) Department of Communication Science and EngineeringFudan UniversityShanghai 200433China National Institute of LED on Silicon Substrate Nanchang UniversityNanchang 330096China

In recent studies, visible light communication(VLC) has been predicted to be a prospective technique in the future 6G communication systems. To suit the trend of exponentially growing connectivity, researchers have intensively studied techniques that enable multiple access(MA) in VLC systems, such as the MIMO system based on LED devices to support potential applications in the Internet of Things(IoT) or edge computing in the nextgeneration access network. However, their transmission rate is limited due to the intrinsic bandwidth of ***, the majority of visible light laser communication (VLLC) research with beyond 10 Gb/s data rates concentrates on point-to-point links, or using discrete photodetector(PD) devices instead of an integrated array PD. In this paper, we demonstrated an integrated PD array device fabricated with a Si-substrated GaN/InGaN multiple-quantum-well(MQW) structure, which has a 4 × 4 array of 50 μm × 50 μm micro-PD units with a common cathode and anode. This single-integrated array successfully provides access for two different transmitters simultaneously in the experiment, implementing a 2 × 2 MIMO-VLLC link at 405 nm. The highest data rate achieved is 13.2 Gb/s, and the corresponding net data rate(NDR) achieved is 12.27 Gb/s after deducing the FEC overhead, using 2.2 GHz bandwidth and superposed PAM signals. Furthermore, we assess the Huffman-coded coding scheme, which brings a fine-grain adjustment in access capacity and enhances the overall data throughput when the user signal power varies drastically due to distance, weather, or other challenges in the channel condition. As far as we know, this is the first demonstration of multiple visible light laser source access based on a single integrated GaN/InGaN receiver module.

关键词： communication visible light

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Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing

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National Science Review 2024年第2期11卷 196-206页

作者： Man luo Qin Wang Gang Zhao Wei Jiang Cici Zeng qingao Zhang Ruyu Yang Wang Dong Yunxi Zhao Guozhen Zhang Jun Jiang Yucai Wang qing Zhu Key Laboratory of Precision and Intelligent Chemistry School of Chemistry and Materials Science University of Science and Technology of China Department of Radiology The First Affiliated Hospital of University of Science and Technology of China Division of Life Sciences and Medicine University of Science and Technology of China Shenzhen Senior High School Institute of Intelligent Innovation Henan Academy of Sciences

Hydrogen therapy shows great promise as a versatile treatment method for diseases associated with the overexpression of reactive oxygen and nitrogen species（RONS）. However, developing an advanced hydrogen therapy platform that integrates controllable hydrogen release, efficient RONS elimination, and biodegradability remains a giant technical challenge. In this study, we demonstrate for the first time that the tungsten bronze phase H0.53WO3（HWO） is an exceptionally ideal hydrogen carrier, with salient features including temperature-dependent highly-reductive atomic hydrogen release and broad-spectrum RONS scavenging capability distinct from that of molecular hydrogen. Moreover, its unique p H-responsive biodegradability ensures post-therapeutic clearance at pathological sites. Treatment with HWO of diabetic wounds in an animal model indicates that the solid-state atomic H promotes vascular formation by activating M2-type macrophage polarization and anti-inflammatory cytokine production, resulting in acceleration of chronic wound healing. Our findings significantly expand the basic categories of hydrogen therapeutic materials and pave the way for investigating more physical forms of hydrogen species as efficient RONS scavengers for clinical disease treatment.

关键词： atomic hydrogen RONS scavenger inflammatory regulation diabetic wound healing hydrogen therapy

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Improving discharge voltage and ion storage dynamic in polyaniline via modulation of carrier charge density for magnesiummetal batteries

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Nano Research 2024年第7期17卷 6168-6175页

作者： Ping luo Feiyang chao Chunli Zuo Wenwei Zhang Fangyu Xiong Zhen Huang Dongyao Zhu Gongtao Yu Wenhui Zhong Xingbao Chen Han Tang Xiujuan Wei Qinyou An Hubei Provincial Key Laboratory of Green Materials for Light Industry School of Materials and Chemical EngineeringHubei University of TechnologyWuhan 430068China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Institute for Sustainable Transformation School of Chemical Engineering and Light IndustryGuangdong University of TechnologyGuangzhou 510006China

Rechargeable magnesium-metal batteries(RMBs)have gained much attention due to their abundant resources as well as high ***,the high charge density of Mg^(2+)is one of the main reasons for the slow kinetics performance of RMBs,and modulation of the charge density is an important strategy to improve the kinetics and electrochemical performance of ***,we report on the conductive polymer polyaniline(PANI)for RMBs,which is found to have excellent kinetics and high discharge voltage when storing MgCl^(+).In the storage of MgCl^(+),PANI exhibits a high average discharge voltage platform is 2.3 V ***^(2+)/Mg,which is higher than that in storage of Mg^(2+).We demonstrated the reversible intercalation/de-intercalation of MgCl^(+)in PANI accompanying with the reversible transformation between the quinone ring(C–C,–N=)and the benzene ring(C=C,–NH–)during charging and *** functional theory calculation reveals that PANI exhibit higher voltages(2.25 V vs.1.82 V)along with lower diffusion energy barriers(1.27 eV vs.1.55 eV)for MgCl^(+)storage compared to Mg^(2+)*** work refines the storage mechanism of PANI in RMBs and provides new guidelines for the application of PANI in RMBs.

关键词： rechargeable magnesium-metal batteries cathode materials polyaniline MgCl+storage

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Characterization of the CpsQ Regulon Reveals Its Role in the Transcription of Type Ⅵ Secretion System 2 Genes in Vibrio parahaemolyticus

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Biomedical and Environmental Sciences 2024年第4期37卷 436-439页

作者： luo Xi LI Xue ZHANG Miao Miao HUANG qing Lian ZHANG Yi Quan JI Shen Jie LU Ren Fei Department of Clinical Laboratory Affiliated Nantong Hospital 3 of Nantong UniversityNantong Third People’s HospitalNantong 226006JiangsuChina Department of Clinical Laboratory Qidong People’s HospitalQidong 226200JiangsuChina

Vibrio parahaemolyticus,a gram-negative halophilic bacterium that naturally inhabits coastal waters,causes gastroenteritis,skin infections,and septicemia in human beings[1].This bacterium produces multiple virulence factors,including thermostable direct hemolysin(TDH),TDH-related hemolysin(TRH),type Ⅲ secretion system 1(T3SS1),T3SS2,type Ⅵ secretion system 1(T6SS1),and T6SS2[1].Furthermore,Ⅴ.parahaemolyticus forms biofilms on the surface,which help it in adapting to unfavorable conditions[2].Mature biofilm formation requires special structures,including lateral and polar flagella,exopolysaccharide(EPS),and type Ⅳ pili[2].

关键词： coastal system T3SS

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The quantum Ising model for perfect matching and solving it with variational quantum eigensolver

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Science China(Information Sciences) 2024年第09期67卷 306-320页

作者： Qilin ZHENG Pingyu ZHU chao WU Miaomiao YU Weihong luo Ping XU Institute for Quantum Information and State Key Laboratory of High Performance Computing College of Computer Science and Technology National University of Defense Technology Hefei National Laboratory

Obtaining all perfect matchings of a graph is a tough problem in graph theory, and its complexity belongs to the #P-Complete class. The problem is closely related to combinatorics, marriage matching problems, dense subgraphs, the Gaussian boson sampling, chemical molecular structures, and dimer *** this paper, we propose a quadratic unconstrained binary optimization formula of the perfect matching problem and translate it into the quantum Ising model. We can obtain all perfect matchings by mapping them to the ground state of the quantum Ising Hamiltonian and solving it with the variational quantum eigensolver. Adjusting the model's parameters can also achieve the maximum or minimum weighted perfect matching. The experimental results on a superconducting quantum computer of the Origin Quantum Computing Technology Company show that our model can encode 2~n dimensional optimization space with only O（n） qubits consumption and achieve a high success probability of the ground state corresponding to all perfect matchings. In addition, the further simulation results show that the model can support a scale of more than 14 qubits, effectively resist the adverse effects of noise, and obtain a high success probability at a shallow variational depth. This method can be extended to other combinatorial optimization problems.

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Insights into the history and tendency of glycosylation and digestive system tumor:A bibliometric-based visual analysis

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1059-1075页

作者： Jie Jiang Zai luo Ren-chao Zhang Yue-Ling Wang Jun Zhang Ming-Yu Duan Zheng-Jun Qiu Chen Huang Department of Gastrointestinal Surgery Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Jiangnan University Wuxi School of Medicine Wuxi 214122Jiangsu ProvinceChina Department of Education Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

BACKGROUND Glycosylation,a commonly occurring post-translational modification,is highly expressed in several tumors,specifically in those of the digestive system,and plays a role in various cellular pathophysiological *** the importance and detection methods of glycosylation in digestive system tumors have garnered increasing attention in recent years,bibliometric analysis of this field remains *** present study aims to identify the developmental trends and research hotspots of glycosylation in digestive system *** To find and identify the developmental trends and research hotspots of glycosylation in digestive system *** We obtained relevant literature from the Web of Science Core Collection and employed VOSviewer 1.6.19 and CiteSpace(version 6.1.R6)to perform bibliometric *** A total of 2042 documents spanning from 1978 to the present were analyzed,with the research process divided into three phases:the period of obscurity(1978-1990),continuous development period(1991-2006),and the rapid outbreak period(2007-2023).These documents were authored by researchers from 66 countries or regions,with the United States and China leading in terms of publication *** Celso A had the highest number of publications,while Pinho SS was the most cited ***-occurrence analysis revealed the most popular keywords in this field are glycosylation,expression,cancer,colorectal cancer,and pancreatic ***,the Journal of Proteome Research was the most prolific journal in terms of publications,while the Journal of Biological Chemistry had the most *** The bibliometric analysis shows current research focus is primarily on basic research in this ***,future research should aim to utilize glycosylation as a target for treating tumor patients.

关键词： Glycosylation Cancer Digestive system Bibliometric analysis CiteSpace VOS viewer

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Rheum palmatum L. and Salvia miltiorrhiza Bge. Alleviates Acute Pancreatitis by Regulating Th17 Cell Differentiation: An Integrated Network Pharmacology Analysis, Molecular Dynamics Simulation and Experimental Validation

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Chinese Journal of Integrative Medicine 2024年第5期30卷 408-420页

作者： FENG Min-chao luo Fang HUANG Liang-jiang LI Kai CHEN Zu-min LI Hui YAO Chun QIN Bai-jun CHEN Guo-zhong The First Clinical Medical College Guangxi University of Traditional Chinese MedicineNanning 530000China Guangxi Key Laboratory of Molecular Biology of Traditional Chinese Medicine and Preventive Medicine Nanning 530000China Graduate School Guangxi University of Traditional Chinese MedicineNanning 530000China Department of Gastroenterology the First Affiliated Hospital of Guangxi University of Traditional Chinese MedicineNanning 530023China

Objective: To identify the core targets of Rheum palmatum L. and Salvia miltiorrhiza Bge.,(Dahuang-Danshen, DH-DS) and the mechanism underlying its therapeutic efficacy in acute pancreatitis(AP)using a network pharmacology approach and validate the findings in animal experiments. Methods: Network pharmacology analysis was used to elucidate the mechanisms underlying the therapeutic effects of DH-DS in AP. The reliability of the results was verified by molecular docking simulation and molecular dynamics ***, the results of network pharmacology enrichment analysis were verified by immunohistochemistry,Western blot analysis and real-time quantitative PCR, respectively. Results: Sixty-seven common targets of DH-DS in AP were identified and mitogen-activated protein kinase 3(MAPK3), Janus kinase 2(JAK2), signal transducer and activator of transcription 3(STAT3), protein c-Fos(FOS) were identified as core targets in the protein interaction(PPI) network analysis. Gene ontology analysis showed that cellular response to organic substance was the main functions of DH-DS in AP, and Kyoto Encyclopedia of Genes and Genomes analysis showed that the main pathway included Th17 cell differentiation. Molecular docking simulation confirmed that DH-DS binds with strong affinity to MAPK3, STAT3 and FOS. Molecular dynamics simulation revealed that FOS-isotanshinone Ⅱ and STAT3-dan-shexinkum d had good binding capacity. Animal experiments indicated that compared with the AP model group, DH-DS treatment effectively alleviated AP by inhibiting the expression of interleukin-1β, interleukin-6 and tumor necrosis factor-α, and blocking the activation of Th17 cell differentiation(P<0.01). Conclusion: DH-DS could inhibit the expression of inflammatory factors and protect pancreatic tissues,which would be functioned by regulating Th17 cell differentiation-related m RNA and protein expressions.

关键词： Rheum palmatum L. Salvia miltiorrhiza Bge. molecular docking simulation network pharmacology acute pancreatitis Th17 cell differentiation

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Gastric metastasis of small cell lung carcinoma:Three case reports and review of literature

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World Journal of Gastroenterology 2024年第31期30卷 3717-3725页

作者： Shan Yang qing-Yun He qing-Jing Zhao Han-Tao Yang Zheng-Yi Yang Wen-Yi Che Hua-Mei Li Hui-chao Wu Department of Gastroenterology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Gastroenterology Guizhou Hospital of The First Affiliated HospitalSun Yat-sen UniversityGuiyang 550000Guizhou ProvinceChina Department of Gastroenterology Zhejiang Provincial People's Hospital Bijie HospitalBijie 551700Guizhou ProvinceChina Department of Gastroenterology Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Small cell lung carcinoma(SCLC)is highly susceptible to metastasis in the early stages of the ***,the stomach is an uncommon site of metastasis in SCLC,and only a few cases of this type of metastasis have been ***,SCLC gastric metastases have not been systematically characterized and are easily missed and *** SUMMARY We report three cases of gastric metastasis from SCLC in this *** first patient presented primarily with cough,hemoptysis,and epigastric *** other two patients presented primarily with abdominal discomfort,epigastric distension,and *** patients underwent gastroscopy and imaging ***,the immunohistochemical results of the lesions in three patients were suggestive of small cell ***,the three patients were diagnosed with gastric metastasis of SCLC through a comprehensive *** three patients did not receive appropriate treatment and died within a short *** Here,we focused on summarizing the characteristics of gastric metastasis of SCLC to enhance clinicians'understanding of this disease.

关键词： Small cell lung cancer Gastric neoplasms Neoplasm metastasis Diagnosis Case report

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Factors and Their Impact on Treatment Effect of Acupuncture in Different Outcomes:A Meta-Regression of Acupuncture Randomized Controlled Trials

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Chinese Journal of Integrative Medicine 2024年第3期30卷 260-266页

作者： XIU Wen-cui GANG Wei-juan ZHOU Qi SHI Lan-jun HU Xiang-yu MING Tian-yu luo Zhen ZHANG Yu-qing JING Xiang-hong Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing100700China China Center for Evidence-Based Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing100700China Department of Health Research Methods Evidenceand ImpactMcMaster UniversityHamiltonOntarioL8S 4L8Canada Center for Evidence-Based Integrative Medicine-Clarity Collaboration Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China

Background:The effects of acupuncture have varied in different randomized controlled trials(RCTs),and there are many factors that influence treatment effect of acupuncture in different outcomes,with conflicting ***:To identify factors and their impact on the treatment effect of acupuncture in different ***:Acupuncture RCTs were searched from 7 databases including Medline(Pub Med),Embase,Cochrane Central Register of Controlled Trials,China National Knowledge Infrastructure,Wanfang Database,VIP Database,and China Biology Medicine disc between January 1st,2015 and December 31st,*** studies must compare acupuncture to no acupuncture,sham acupuncture,or waiting lists,and report at least 1patient-important outcome.A multi-level meta-regression was conducted using a 3-level robust mixed model and univariate analyses were performed for all independent variables,even those excluded from the multivariable model due to *** used thresholds of 0.2 and 0.4 for the difference of standardized mean differences(SMDs),categorising them as small(0.4) ***:The pain construct analysis involved 211 effect estimates from 153 studies and 14 independent ***-frequency acupuncture treatment sessions produced larger effects compared to low-frequency sessions [large magnitude,the difference of adjusted SMDs 0.46,95% confidence interval(CI) 0.07 to 0.84;P=0.02].The non-pain symptoms construct analysis comprised 323 effect estimates from 231 studies and 15 independent *** acupuncture showed moderately larger effects when compared to non-penetrating acupuncture(0.30,95% CI 0.06 to 0.53;P=0.01).The function construct analysis included 495 effect estimates from 274 studies and 14 independent *** acupuncture and the flexible acupuncture regimen showed moderately larger effects,compared to non-penetrating acupuncture and fixed regimen,respectively(0.40,95% CI 0

关键词： acupuncture randomized controlled trial patient-important outcome meta-regression

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Effects of high-quality neurosurgical nursing care on improving clinical nursing quality

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World Journal of Clinical Cases 2024年第22期12卷 4999-5007页

作者： Xiu-Rong Li qing-Lian luo Department of Neurosurgery The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND With continuous advancements in medical technology,neurosurgical nursing is constantly developing and improving to provide higher-quality nursing *** To explore the effects of different types of high-quality nursing care on clinical nursing quality and patient satisfaction in neurosurgical *** Eighty patients who received neurosurgical treatment in the Affiliated Hospital of Southwest Medical University from June to December 2020 were selected as study participants and categorised into study and control *** study group comprised 40 patients who received 4 different types of high-quality nursing care,whereas the control group comprised 40 patients who received conventional nursing *** a specific period,nursing satisfaction levels and adverse event and complication rates were compared between the two *** Satisfaction with high-quality care was higher than that with conventional care,and high-quality health services and regional services showed the highest satisfaction levels,with an average score of 12 on the Glasgow *** satisfaction levels of the study and control groups were 75%and 57%,respectively,with a statistically significant difference(t=7.314,P<0.05).During the nursing period,the adverse event and complication rates were the highest in patients with level III pathology grade and those who underwent neurosurgery(40.02%and 85.93%,respectively),and the difference was statistically *** In neurosurgical nursing,employing appropriate high-quality nursing methods can effectively reduce adverse event and complication rates in patients,thereby improving the quality of nursing care and increasing clinical nursing value.

关键词： High-quality nursing Neurosurgery Quality care Adverse event Complication

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