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High Voltage 2024年第2期9卷 474-483页

作者： Zhenglin Zeng Jinshan Qin Zuhao Wang Weimin Tan chao tang College of Engineering and Technology Southwest UniversityChongqingChina International R&D Center for New Technologies of Smart Grid and Equipment ChongqingChina

The moisture generated by the ageing of the oil-paper insulating system can easily lead to the deterioration of the performance of the insulating *** order to alleviate the impact of moisture on the performance of the insulating paper,we developed a kind of lipophilic hydrophobic self-repairing cellulose insulating paper(new insulating paper)based on the ternary system of polytetrafluoroethylene,fluorocarbon surfactant and fluorinated alkyl silane,and accelerated thermal ageing test for 45 days at 130°C was carried *** experimental results show that the new insulating paper with excellent lipophilic property can realise hydrophobic self-repairing through heat treatment after physical *** tensile strength and elongation at break of the new insulating paper increased by 5%–8%and 6.25%–27%respectively compared with the original cellulose insulating *** the end of ageing,the relative dielectric constant and dielectric loss factor of new insulating paper are 10.4%and 9.9%lower than that of the original cel-lulose insulating paper,while the breakdown voltage is 6.8%*** acid and moisture content produced during the ageing process of the insulating oil impregnated with new insulating paper are also less,indicating that the coating can delay the ageing of the insulating paper.

关键词： coating moisture cellulose

Serum metabolic profiling implicates mTOR activation and insulin resistance in the development of pulmonary hypertension in a rat model of pressure overload-induced heart failure

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Genes & Diseases 2024年第5期11卷 109-112页

作者： Qi Zhou chao tang Xinke Xu Junhao Hu Shengsen Yao Bo Dong Xiaojing Wu Department of Cardiology of the Fifth Affiliated Hospital of Southern Medical University GuangzhouGuangdong 510999China Cardiovascular Department of Shenzhen University General Hospital ShenzhenGuangdong 518055China Cardiovascular Department of Chongqing Medical University Second Affiliated Hospital Chongqing 400010China

Pulmonary hypertension(PH)due to left heart failure(HF)accounts for approximately half of PH cases *** has been demonstrated that PH is a frequent complication of HF but is difficult to recognize in its early stage because it is characterized by nonspecific symptoms including shortness of breath and decreased tolerance of ***,nearly all multicentric clinical trials targeting pulmonary circulation in PH-HF have reported negative results.1 Thus,there are no effective methods for diagnosing early PH,and the current treatment of PH-HF is insufficient.

关键词： hypertension Serum resistance

GNAS mutations suppress cell invasion by activating MEG3 in growth hormone–secreting pituitary adenoma

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Oncology Research 2024年第6期32卷 1079-1091页

作者： chao tang CHUNYU ZHONG JUNHAO ZHU FENG YUAN JIN YANG YONG XU CHIYUAN MA Department of Neurosurgery Affiliated Jinling HospitalMedical School of Nanjing UniversityNanjing210002China Department of Neurosurgery Children’s Hospital of Nanjing Medical UniversityNanjing210019China Affiliated Eye Hospital Nanjing Medical UniversityNanjing210029China Department of Neurosurgery Jinling HospitalSouthern Medical UniversityNanjing210002China Department of Neurosurgery Jinling HospitalNanjing Medical UniversityNanjing210002China

Approximately 30%–40%of growth hormone–secreting pituitary adenomas(GHPAs)harbor somatic activating mutations in GNAS(αsubunit of stimulatory G protein).Mutations in GNAS are associated with clinical features of smaller and less invasive ***,the role of GNAS mutations in the invasiveness of GHPAs is *** mutations were detected in GHPAs using a standard polymerase chain reaction(PCR)sequencing *** expression of mutation-associated maternally expressed gene 3(MEG3)was evaluated with ***3 was manipulated in GH3 cells using a lentiviral expression *** invasion ability was measured using a Transwell assay,and epithelial–mesenchymal transition(EMT)-associated proteins were quantified by immunofluorescence and western ***,a tumor cell xenograft mouse model was used to verify the effect of MEG3 on tumor growth and *** invasiveness of GHPAs was significantly decreased in mice with mutated GNAS compared with that in mice with wild-type ***,the invasiveness of mutant GNASexpressing GH3 cells ***3 is uniquely expressed at high levels in GHPAs harboring mutated ***,MEG3 upregulation inhibited tumor cell invasion,and conversely,MEG3 downregulation increased tumor cell ***,GNAS mutations inhibit EMT in ***3 in mutated GNAS cells prevented cell invasion through the inactivation of the Wnt/β-catenin signaling pathway,which was further validated in *** data suggest that GNAS mutations may suppress cell invasion in GHPAs by regulating EMT through the activation of the MEG3/Wnt/β-catenin signaling pathway.

关键词： GHPAs GNAS mutation MEG3 β-catenin EMT

Stroke:challenges and opportunities--Perspectives on clinical research advances and future outlook in 2024

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Clinical Research Communications 2024年第1期7卷 1-2页

作者： chao-Liang tang Department of Anesthesiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China

Dear readers,In the field of stroke research and treatment,cutting-edge technologies and studies continue to emerge,providing new perspectives and strategies for exploring the mechanisms and treatment methods of *** to the latest advancements,neuroimaging techniques play a crucial role in stroke *** technology,for instance,is essential for evaluating stroke patients.

关键词： instance treatment advances

Day surgery model: a new path for hospital high-quality development

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Clinical Research Communications 2024年第2期7卷 1-3页

作者： chao-Liang tang Department of Anesthesiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China.

In the current healthcare system,the day surgery model is increasingly valued and has become an important driving force for the high-quality development of *** day surgery model refers to a medical model where patient... 详细信息

关键词： surgery driving hospital

Experimental Study on Engineering Behavior of Solidified Soil for Scour Repair and Protection

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China Ocean Engineering 2024年第4期38卷 625-635页

作者： WU Xiao-ni LI Ru-yu SHU Jian tang chao CHEN Jin-jian WANG Hui-li JIANG Hai-li WANG Xiao State Key Laboratory of Ocean Engineering Department of Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Shanghai Road and Bridge Group Co. Ltd.Shanghai 200433China Shanghai Engineering Research Center of Urban Infrastructure Renewal Shanghai 200032China Jiangsu Kunze Technology Co. Ltd.Nanjing 210000China

A new scour countermeasure using solidified slurry for offshore foundation has been proposed *** solidified slurry is pumped to seabed area around foundation for scour protection or pumped into the developed scour holes for scour repair as the fluidized material solidifies *** the pumping operation and solidification,the engineering behaviors of solidified slurry require to be considered synthetically for the reliable application in scour repair and protection of ocean engineering such as the pumpability related flow value,flow diffusion behavior related rheological property,anti-scour performance related retention rate in solidification and bearing capacity related strength property after *** this study,a series of laboratory tests are conducted to investigate the effects of mix proportion(initial water content and binder content)on the flow value,rheological properties,density,retention rate of solidified slurry and unconfined compressive strength(UCS).The results reveal that the flow value increases with the water content and decreases with the binder *** the solidified slurry exhibits Bingham plastic behavior when the shear rate is larger than 5 s^(-1).The Bingham model has been employed to fit the rheology test results,and empirical formulas for obtaining the density,yield stress and viscosity are established,providing scientific support for the numerical assessment of flow and diffusion of solidified *** rate of solidified slurry decreases with the water flow velocity and flow value,which means the pumpability of solidified slurry is contrary to anti-scour *** unconfined compressive strength after solidification reduces as the water content increases and binder content decreases.A design and application procedure of solidified soil for scour repair and protection is also proposed for engineering reference.

关键词： scour repair and protection solidified soil pumpability strength flow properties anti-scour performance

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面向DNA甲基化修饰分析的质谱技术

化学通报 2024年第1期87卷 27-35页

作者：唐朝罗群江汉大学环境与健康学院武汉430056 中国科学院化学研究所北京100190

DNA甲基化作为表观遗传修饰中一种重要的调控方式,通过调控基因的表达,从而影响机体内一系列的生物学过程。色谱-质谱法是研究DNA甲基化修饰的重要研究手段。随着对哺乳动物DNA甲基化的生物学功能的深入研究,应用于研究表观遗传修饰的... 详细信息

DNA甲基化作为表观遗传修饰中一种重要的调控方式,通过调控基因的表达,从而影响机体内一系列的生物学过程。色谱-质谱法是研究DNA甲基化修饰的重要研究手段。随着对哺乳动物DNA甲基化的生物学功能的深入研究,应用于研究表观遗传修饰的手段与仪器设备越来越先进。为了对DNA修饰进行定性与定量的分析检测,除了高效液相色谱整合不同种类质量分析器的质谱联用(HPLC-MS)技术外,目前还开发应用了基质辅助激光解析质谱技术(MALDI-ToF-MS)和气相色谱-质谱联用技术(GC-MS),从而极大拓展了DNA甲基化修饰研究的手段。本文对分析表观遗传DNA甲基化修饰的质谱技术发展进行综述,希望为DNA甲基化修饰分析提供有价值的研究策略。

关键词：表观遗传修饰 DNA甲基化同位素标记液相色谱与质谱联用技术

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WebRTC协议在线上教学中的应用实践

福建电脑 2024年第7期40卷 41-47页

作者：唐超湖北开放大学软件工程学院武汉430074

为加快教育数字化转型和完善教学信息化供给侧结构性改革,本文提出了一个用于日常实时视频教学的软件解决方案。该方案基于WebRTC协议及其对应的开源软件框架,利用WebRTC协议作为HTML5标准子集并聚焦音视频实时通信场景,依托浏览器-服... 详细信息

为加快教育数字化转型和完善教学信息化供给侧结构性改革,本文提出了一个用于日常实时视频教学的软件解决方案。该方案基于WebRTC协议及其对应的开源软件框架,利用WebRTC协议作为HTML5标准子集并聚焦音视频实时通信场景,依托浏览器-服务器模式构建适用于网页在线音视频会议和教学的架构模型。方案的实现可有效推进教育数字化转型。

关键词：网页实时通信协议教学信息化视频教学

基于多模态注意力网络的红外人体行为识别方法

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计算机科学 2024年第8期51卷 232-241页

作者：汪超唐超王文剑张靖合肥学院人工智能与大数据学院合肥230601 山西大学计算机与信息技术学院太原030006 中国科学技术大学研究生院科学岛分院合肥230031

深度学习网络对红外单一模态数据的学习表征能力具有一定的局限性,针对该问题,文中提出了基于多模态注意力网络的红外人体行为识别方法。由于深度学习网络模型无法直接对视频信息进行训练和分类,首先,通过预处理模块将得到的视频信息预... 详细信息

深度学习网络对红外单一模态数据的学习表征能力具有一定的局限性,针对该问题,文中提出了基于多模态注意力网络的红外人体行为识别方法。由于深度学习网络模型无法直接对视频信息进行训练和分类,首先,通过预处理模块将得到的视频信息预处理成红外视图,再将得到的红外视图通过Sobel算子和基于L 1范数的全变分光流法分别提取红外视图的边缘信息和光流信息得到边缘视图和光流视图;其次,将红外视图、边缘视图、光流视图分别输入融合注意力机制模块的三流网络中进行特征学习;然后,对三流网络中每个网络提取的多模态特征进行融合;最后,将融合得到的特征向量输入随机森林进行训练和分类。在公开数据集NTU RGB+D和自建数据集上进行实验,结果表明了所提方法具有不错的识别效果。

关键词：多模态注意力机制三流网络特征融合随机森林

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安徽当涂县地质灾害分布特征及主控因素分析

现代矿业 2024年第7期40卷 54-56页

作者：唐朝安徽省地质矿产勘查局322地质队

以安徽省当涂县地质灾害为基础依据,对县域内崩塌、滑坡和地面塌陷36处地质灾害隐患点的分布特征和主控因素进行分析研究。研究结果表明,在空间分布上,中北部丘陵区发育程度集中,主要与地层岩性、地形地貌、地质构造和人类工程活动等多... 详细信息

以安徽省当涂县地质灾害为基础依据,对县域内崩塌、滑坡和地面塌陷36处地质灾害隐患点的分布特征和主控因素进行分析研究。研究结果表明,在空间分布上,中北部丘陵区发育程度集中,主要与地层岩性、地形地貌、地质构造和人类工程活动等多种因素有关;在时间分布上,当涂县地质灾害主要集中在降雨季节,特别是3—7月,为研究区地质灾害的高发期。研究结果不仅可以更好地了解当涂县地质灾害的分布情况和主控因素,为防灾减灾提供科学依据,同时也可以为土地利用规划、城市建设等领域提供技术支持。

关键词：地质灾害滑坡地面塌陷主控因素分析