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An observed nocturnal ozone transport event in the Sichuan Basin,Southwestern China

Journal of Environmental Sciences 2024年第4期138卷 10-18页

作者： Ruyue Guo Guangming Shi Dan Zhang Yang chen chao Peng Chongzhi Zhai Fumo Yang Department of Environmental Science and Engineering Sichuan UniversityChengdu 610065China College of Carbon Neutrality Future Technology Sichuan UniversityChengdu 610065China National Engineering Research Center on Flue Gas Desulfurization Chengdu 610065China Chongqing Academy of Eco-Environmental Science Chongqing 401147China Research Center for Atmospheric Environment Chongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China Key Laboratory for Urban Atmospheric Environment Integrated Observation&Pollution Prevention and Control of Chongqing Chongqing 401147China

The ozone(O_(3))pollution in China drew lots of attention in recent years,and the Sichuan Basin(SCB)was one of the regions confronting worsening O_(3)pollution *** previous studies have shown that regional transport is an important contributor to O_(3)***,very few features of the O_(3)profile during transport have been reported,especially in the border regions between different administrative *** this study,we conducted tethered balloon soundings in SCB during the summer of 2020 and captured a nocturnal O_(3)transport event during the ***,the O_(3)transport occurred in the bottom of the residual layer,between 200 and 500 m above ground ***,the transport pathway was directed from southeast to northwest based on the analysis of the wind field and air mass *** effect of transport in the residual layer on the surface O_(3)concentration was related to the spatial distribution of O_(3).For cities with high O_(3)concentrations in the upwind region,the transport process would bring clean air masses and abate *** downwind lightly polluted cities,the transport process would slow down the decreasing or even increase the surface O_(3)concentration during the *** provided observational facts on the profile features of a transboundary O_(3)transport event between two provincial administrative divisions,which implicated the importance of joint prevention and control ***,the sounding parameters were limited and the quantitative analysis was preliminary,more integrated,and thorough studies of this topic were called for in the future.

关键词： Ozone Sichuan basin Transport event Vertical profile

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Engineered extracellular vesicles: A new approach for targeted therapy of tumors and overcoming drug resistance

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Cancer Communications 2024年第2期44卷 205-225页

作者： chen Ming-Kun chen Zi-Xian Cai Mao-Ping chen Hong chen Zhuang-Fei Zhao Shan-chao Department of Urology The Third Affiliated Hospital of Southern Medical UniversityGuangzhouGuangdongP.R.China The Third Clinical College Southern Medical UniversityGuangzhouGuangdongP.R.China Luoyang Key Laboratory of Organic Functional Molecules College of Food and DrugLuoyang Normal UniversityLuoyangHenanP.R.China Department of Urology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China

Targeted delivery of anti-tumor drugs and overcoming drug resistance in malig-nant tumor cells remain significant clinical ***,there are only few effective methods to address these *** vesicles(EVs),actively secreted by cells,play a crucial role in intercellular information transmis-sion and cargo *** studies have demonstrated that engineered EVs can serve as drug delivery carriers and showed promising application ***,there is an urgent need for further improvements in the isolation and purification of EVs,surface modification techniques,drug assem-bly processes,and precise recognition of tumor cells for targeted drug delivery *** this review,we summarize the applications of engineered EVs in cancer treatment and overcoming drug resistance,and current challenges asso-ciated with engineered EVs are also *** review aims to provide new insights and potential directions for utilizing engineered EVs as targeted delivery systems for anti-tumor drugs and overcoming drug resistance in the near future.

关键词： drug delivery drug resistance extracellular vesicles nanoparticles

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Image Recognition Model of Fraudulent Websites Based on Image Leader Decision and Inception-V3 Transfer Learning

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China Communications 2024年第1期21卷 215-227页

作者： Shengli Zhou cheng Xu Rui Xu Weijie Ding chao chen Xiaoyang Xu Information Department of Zhejiang Police College Hangzhou 310053China Hangzhou Dianzi University Hangzhou 310018China Big Data Laboratory of Zhejiang Police College Hangzhou 310053China Hangzhou Public Security Bureau Hangzhou 310002China

The fraudulent website image is a vital information carrier for telecom *** efficient and precise recognition of fraudulent website images is critical to combating and dealing with fraudulent *** research on image recognition of fraudulent websites is mainly carried out at the level of image feature extraction and similarity study,which have such disadvantages as difficulty in obtaining image data,insufficient image analysis,and single identification *** study develops a model based on the entropy method for image leader decision and Inception-v3 transfer learning to address these *** data processing part of the model uses a breadth search crawler to capture the image ***,the information in the images is evaluated with the entropy method,image weights are assigned,and the image leader is *** model training and prediction,the transfer learning of the Inception-v3 model is introduced into image recognition of fraudulent *** selected image leaders to train the model,multiple types of fraudulent websites are identified with high *** experiment proves that this model has a superior accuracy in recognizing images on fraudulent websites compared to other current models.

关键词： fraudulent website image leaders telecom fraud transfer learning

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Intake of tobacco nitrosamines of smokers in various provinces of China and their cancer risk:A meta-analysis

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Journal of Environmental Sciences 2024年第7期141卷 249-260页

作者： Xiao Li Zhiwei Ye Jun Wang Pengfei Lin Xiaojin Zhang Shuguang Xie chao chen Research Institute for Environmental Innovation(Suzhou) TsinghuaSuzhouJiangsu 215163China State Key Joint Laboratory of Environmental Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China Shenzhen Key Laboratory of Organic Pollution Prevention and Control State Key Laboratory of Urban Water Resource and EnvironmentHarbin Institute of TechnologyShenzhen 518055China State Key Joint Laboratory of Environmental Simulation and Pollution Control College of Environmental Science and EngineeringPeking UniversityBeijing 100871China

Nitrosamines are a class of carcinogens which have been detected widely in food,water,some pharmaceuticals as well as *** objectives of this paper include reviewing the basic information on tobacco consumption and nitrosamine contents,and assessing the health risks of tobacco nitrosamines exposure to Chinese *** searched the publications in English from“Web of Science”and those in Chinese from the“China National Knowledge Infrastructure”in 2022 and collected 151 literatures with valid *** content of main nitrosamines in tobacco,including 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone(NNK),N-nitrosonornicotine(NNN),N-nitrosoanatabine(NAT),N-nitrosoanabasine(NAB),total tobacco-specific nitrosamines(TSNA),and N-nitrosodimethylamine(NDMA)were *** information of daily tobacco consumption of smokers in 30 provinces of China was also ***,the intakes of NNN,NNK,NAT,NAB,TSNAs,and NDMA via tobacco smoke were estimated as 1534ng/day,591 ng/day,685 ng/day,81 ng/day,2543 ng/day,and 484 ng/day by adult smokers in30 provinces,*** cancer risk(CR)values for NNN and NNK inhalation intake were further calculated as 1.44×10^(-5)and 1.95×10^(-4).The CR value for NDMA intake via tobacco smoke(inhalation:1.66×10^(-4))indicates that NDMA is similarly dangerous in tobacco smoke when compared with the *** China,the CR values caused by average nitrosamines intake via various exposures and their order can be estimated as the following:smoke(3.75×10^(-4))>food(1.74×10^(-4))>drinking water(1.38×10^(-5)).Smokers in China averagely suffer 200%of extra cancer risk caused by nitrosamines in tobacco when compared with non-smokers.

关键词： N-nitrosamine Tobacco Cancer risk Tobacco specific nitrosamines(TSNAs) N-nitrosodimethylamine(NDMA)

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“Hepatic hilum area priority,liver posterior first”:An optimized strategy in laparoscopic resection for type Ⅲ-Ⅳ hilar cholangiocarcinoma

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2167-2174页

作者： Xiao-Si Hu Yong Wang Hong-Tao Pan chao Zhu Shi-Lei chen Shuai Zhou Hui-Chun Liu qing Pang Hao Jin Department of Hepatopancreatobiliary Surgery Anhui No.2 Provincial People's HospitalHefei 230041Anhui ProvinceChina

BACKGROUND In recent years,pure laparoscopic radical surgery for Bismuth-Corlette type Ⅲ and Ⅳ hilar cholangiocarcinoma(HCCA)has been preliminarily explored and applied,but the surgical strategy and safety are still worthy of further improvement and *** To summarize and share the application experience of the emerging strategy of“hepatic hilum area dissection priority,liver posterior separation first”in pure laparoscopic radical resection for patients with HCCA of Bismuth-Corlette types Ⅲ and *** The clinical data and surgical videos of 6 patients with HCCA of Bismuth-Corlette types Ⅲ and Ⅳ who underwent pure laparoscopic radical resection in our department from December 2021 to December 2023 were retrospectively *** Among the 6 patients,4 were males and 2 were *** average age was 62.2±11.0 years,and the median body mass index was 20.7(19.2-24.1)kg/m^(2).The preoperative median total bilirubin was 57.7(16.0-155.7)μmol/*** patient had Bismuth-Corlette type Ⅲa,4 patients had Bismuth-Corlette type Ⅲb,and 1 patient had Bismuth-Corlette type Ⅳ.All patients successfully underwent pure laparoscopic radical resection following the strategy of“hepatic hilum area dissection priority,liver posterior separation first”.The operation time was 358.3±85.0 minutes,and the intraoperative blood loss volume was 195.0±108.4 *** of the patients received blood transfusions during the perioperative *** median length of stay was 8.3(7.0-10.0)*** bile leakage occurred in 2 patients,and all patients were discharged without serious surgery-related *** The emerging strategy of“hepatic hilum area dissection priority,liver posterior separation first”is safe and feasible in pure laparoscopic radical surgery for patients with HCCA of Bismuth-Corlette types Ⅲ and Ⅳ.This strategy is helpful for promoting the modularization and process of pure laparoscopic radical surgery for complicated HCCA,shortens the learning curve,and

关键词： Hilar cholangiocarcinoma Bismuth-Corlette typesⅢandⅣ Laparoscopy Radical resection Strategy

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Preparation and improved energy storage capability of nanocomposites utilizing ultrathin 2D HfO_(2)@TiO_(2)nanosheets

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Journal of Advanced Dielectrics 2024年第2期14卷 42-53页

作者： chao chen chen Guo Xiaoyong Wei Pengfei Wang Xi’an Institute of Optics and Precision Mechanics Chinese Academy of Sciences(CAS) Xi’an 710119China Electronic Materials Research Laboratory Key Laboratory of the Ministry of Education and International Center for Dielectric ResearchXi’an Jiaotong University Xi’an 710049China

Polymer-based dielectrics play an important role in electrostatic capacitor by their high energy density(U_(e))and ***,we designed a simple high Ue polymer-based dielectrics by controlling the morphology and surface modification of inorganic *** decrease the difference in dielectric properties between fillers and matrix of the nanocomposites,HfO_(2)acting as the buffer layer with high insulation and appropriate permittivity coated onto the surface of TiO_(2)nanosheets(TiO_(2)Ns)to form a core–shell *** introduction of HfO_(2)@TiO_(2)nanosheets(HfO_(2)@TiO_(2)Ns)makes the nanocomposite with higher dielectric permittivity and lower dielectric loss than poly(vinylidene fluoride-co-hexafluoropropylene)(P(VDF-HFP))*** addition,the HfO_(2)@TiO_(2)Ns can establish an efficient barrier to limit the space charge conduction,hamper the growing electric trees,and the HfO_(2)layer with high insulation could hinder the mobility of charge *** breakdown strength(Eb)of nanocomposite is superior to that of polymer matrix.A small addition of 3 wt.%HfO_(2)@TiO_(2)Ns into P(VDF-HFP)matrix can raise the Eb to 480.7MV/m and present a maximum discharged Ue of 13.9 J/*** work demonstrates that it is an effective strategy to improve the Ue via designing the structure and surface state of inorganic filler simultaneously.

关键词： Nanosheets nanocomposite dielectrics passivation layer breakdown strength energy density

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The complete mitochondrial genomes of five blind scolopendromorph centipedes and phylogenetic within Scolopendromorpha(Chilopoda)

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Zoological Systematics 2024年第4期 299-308页

作者： Tianyun chen chao Jiang State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs National Resource Center for Chinese Materia MedicaChina Academy of Chinese Medical Sciences

Mitochondrial genomes of five Tykhepoda scolopendromorphs(Cryptopidae,Scolopocryptopidae and Plutoniumidae) are sequenced and analyzed using methods of comparative genomics to provide more information on the phylogeny of *** locations of 22 t RNAs, 13 PCGs, and 2 rRNAs are annotated. The heavy chain of mitochondrial genomes are 14,841–15,619 bp in length. A+T % vary from 64.79% to 77.40%,and mitochondrial genomes are CG and AT skewed. The phylogenetic reconstructions showed the blind clade, recently named Tykhepoda, is monophyletic with high support values(BS = 100%and PP = 1).

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Pairing correlation of the kagome-lattice Hubbard model with the nearest-neighbor interaction

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Chinese Physics B 2024年第10期33卷 41-45页

作者： chen Yang chao chen Runyu Ma Ying Liang Tianxing Ma School of Physics and Astronomy Beijing Normal UniversityBeijing 100875China Department of Basic Courses Naval University of EngineeringWuhan 430033China Key Laboratory of Multiscale Spin Physics(Ministry of Education) Beijing Normal UniversityBeijing 100875China

A recently discovered family of kagome lattice materials,AV_(3)Sb_(5)(A=K,Rb,Cs),has attracted great interest,especiallyin the debate over their dominant superconducting pairing *** explore this issue,we study the superconductingpairing behavior within the kagome-lattice Hubbard model through the constrained path Monte Carlo *** isfound that doping around the Dirac point generates a dominant next-nearest-neighbor-d pairing symmetry driven by on-siteCoulomb interaction ***,when considering the nearest-neighbor interaction V,it may induce nearest-neighbor-ppairing to become the preferred pairing *** results provide useful information to identify the dominant superconductingpairing symmetry in the AV_(3)Sb_(5)family.

关键词： kagome-lattice Hubbard model superconductivity pairing symmetry CPMC

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Association between heat and upper urinary tract stones morbidity and medical costs: A study in the subtropical humid climate zone

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Advances in Climate Change Research 2024年第4期15卷 717-724页

作者： chen-Lu YANG Jun-Zhe BAO Peng BI Ya-Dong ZHANG chao-Ming TAN Kai chen College of Public Health Zhengzhou UniversityZhengzhou 450001China School of Public Health The University of AdelaideAdelaide 5000Australia Department of Andrology The First Affliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Nanjing Social Insurance Management Center Nanjing 210008China Department of Environmental Health Sciences Yale UniversityNew Haven 06520USA Yale Center on Climate Change and Health Yale UniversityNew Haven 06520USA

Urolithiasis is a heat-specific *** heat-related urolithiasis susceptibility subtypes,economic burden,and modifying factors could assist governments in targeting interventions to reduce the heat-related health risks of urolithiasis *** collected data on 23,492 patients with upper urinary tract stones(main subtypes of urolithiasis)from 2013 to 2017 in Nanjing,*** adopted generalized additive quasi-Poisson models to examine the associations between daily mean temperatures and morbidity of upper urinary tract stones,while generalized additive Gaussian models were used to explore the relationships between temperatures and log-transformed medical *** examined the modification effects of disease subtypes(kidney and ureteral calculus),sex,and age through stratified analyses and the modif-cation effects of other meteorological factors by introducing interaction terms in the *** found that short-term summer heat exposure has a statistically significant effect on ureteral calculus morbidity but not on kidney calculus *** ureter calculus,a 1℃ temperature increase was associated with a 4.36%(95%confidence interval[CI]:1.94%,6.83%)increase in daily hospitalization and a 5.44%(95%CI:2.71%,8.25%)increase in daily medical *** attributable fraction associated with heat(greater than the median value of daily mean temperature,26.8℃)was 7.85%(95%empirical confidence interval[eCI]:3.64%,11.44%)for hospitalization and 9.36%(95%eCI:4.91%,13.14%)for medical *** effects of heat on ureter calculus morbidity were significantly higher among the males and those with high sunshine duration than females and those with low sunshine ***-term summer heat exposure was associated with increased morbidity and medical costs of ureteral *** government organizations should take effective intervention measures,including community health education,to reduce the health hazards and economic losses caused by heat.

关键词： Heat Upper urinary tract stones Economic burden Modification effects

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In situ Hydrothermal Oxidation of Ternary FeCoNi Alloy Electrode for Overall Water Splitting

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Energy & Environmental Materials 2024年第2期7卷 161-170页

作者： Yuwei chen Lixia Yang chao Li Yuqiu Wu Xiao Lν Hairen Wang Jun'e Qu Key Laboratory for the Green Preparation and Application of Functional Materials Hubei Key Laboratory of Polymer MaterialsSchool of Materials Science and EngineeringHubei UniversityWuhan 430062China Faculty of Material science and Chemistry China University of GeosciencesWuhan 430074China

Exploring noble metal-free catalyst materials for high efficient electrochemical water splitting to produce hydrogen is strongly desired for renewable energy *** this article,a novel bifunctional catalytic electrode of insitu-grown type for alkaline water splitting based on FeCoNi alloy substrate has been successfully prepared via a facile one-step hydrothermal oxidation route in an alkaline hydrogen peroxide *** shows that the matrix alloy with the atom ratio 4∶3∶3 of Fe∶Co∶Ni can obtain the best catalytic performance when hydrothermally treated at 180℃for 18 h in the solution containing 1.8 M hydrogen peroxide and 3.6 M sodium *** as-prepared Fe_(0.4)Co_(0.3)Ni_(0.3)-1.8 electrode exhibits small overpotentials of only 184 and 175 mV at electrolysis current density of 10 mA cm^(-2)for alkaline OER and HER processes,*** overall water splitting at electrolysis current density of 10 mA cm^(-2)can be stably delivered at a low cell voltage of 1.62 *** characteristics including the large specific surface area,the high surface nickel content,the abundant catalyst species,the balanced distribution between bivalent and trivalent metal ions,and the strong binding of in-situ naturally growed catalytic layer to matrix are responsible for the prominent catalytic performance of the Fe_(0.4)Co_(0.3)Ni_(0.3)-1.8 electrode,which can act as a possible replacement for expensive noble metal-based materials.

关键词： alkaline water electrolysis bifunctional electrocatalyst FeCoNi alloy hydrothermal oxidation in-situ growing

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