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The Fourth China-Japan-Korea Joint symposium on Optimization of Structural and Mechanical Systems

作者： Yongbin Lee Sangyup Oh changhyun park Dong-Hoon Choi Research engineer The Center of innovative Design Optimization Technology （iDOT） Hanyang University 17 Haengdang-DongSungdong-Gu Seoul 133-791 Korea Research engineer The Center of innovative Design Optimization Technology （iDOT） Hanyang University 17 Haengdang-DongSungdong-Gu Seoul 133-791 Korea Research engineer The Center of innovative Design Optimization Technology （iDOT） Hanyang University17 Haengdang-DongSungdong-Gu Seoul 133-791 Korea Director The Center of innovative Design Optimization Technology （iDOT） Hanyang University17 Haengdang-DongSungdong-GuSeoul 133-791Korea

＜正＞Support Vector Regression （SVR） is being increasingly used due to its higher accuracy and lower standard deviation than those of existing meta-models. However, while it has been applied to many studies such as the time series prediction and statistical learning theory, SVR has been rarely used for design optimization. In this study, a Sequential Approximate Optimization （SAO） method based on SVR is developed. We adopt the Inherited Latin Hypercube Design （ILHD） for the Design of Experiment （DOE） and the trust region algorithm for the model management technique. Finally, in order to show the accuracy and efficiency of the proposed method, three mathematical problems and a practical design problem are solved and compared a proposed method with SAO using other meta-models such as Kriging, Radial Basis Function （RBF） and Polynomial Regression （PR）. The results show that proposed method not only found exact solution at all problems but also performed more efficiently than other SAO methods about 26%-63%.

关键词： Support Vector Regression Trust Region Algorithm Inherited Latin-Hypercube Design Sequential Approximate Optimization

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<i>A Brief Review</i>: Stage-Convertible Power Amplifier Using Differential Line Inductor

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Wireless Engineering and Technology 2012年第4期3卷 189-194页

作者： Jonghoon park changhyun Lee Changkun park School of Electronic Engineering Soongsil University Seoul Korea

In this review article, a stage-convertible RF power amplifier designed with a 0.18-μm RF CMOS process is described. A method to implement a low-power matching network is an essential technology for the stage-convertible power amplifier. Various low-power matching networks with distributed active transformers as an output power combiner are compared in terms of the amounts of undesired coupling, the chip size, and the amount of power loss. The feasibility of a differential line inductor for the stage-convertible power amplifier is assessed and explained. Finally, we show that the differential line inductor is a realistic means of reducing the overall chip size, enhancing the quality factor of the matching network, and minimizing the undesired coupling between the inter-stage matching network and any output matching network. Additionally, the operating mechanism of the stage-convertible power amplifier using the differential line inductor for a low-power matching network is described in detail.

关键词： Inductor Differential Line Inductor Matching Network Power Amplifier Stage-Convertible

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Increased end-stage renal disease risk in patients with inflammatory bowel disease:A nationwide populationbased study

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World Journal of Gastroenterology 2018年第42期24卷 4798-4808页

作者： Seona park Jaeyoung Chun Kyung-Do Han Hosim Soh Kookhwan Choi Ji Hye Kim Jooyoung Lee changhyun Lee Jong Pil Im Joo Sung Kim Department of Internal Medicine Liver Research InstituteSeoul National University College of Medicine Department of Biostatistics College of MedicineThe Catholic University of Korea Department of Internal Medicine CHA Gangnam Medical CenterCHA University Department of Internal Medicine and Healthcare Research Institute Healthcare System Gangnam CenterSeoul National University Hospital

AIM To estimate the risk of end-stage renal disease(ESRD)in patients with inflammatory bowel disease(IBD).METHODS From January 2010 to December 2013, patients with Crohn's disease(CD) and ulcerative colitis(UC) were identified, based on both the International Classification of Diseases, 10 th revision(ICD-10) and the rare,intractable disease registration program codes from the National Health Insurance(NHI) database in South Korea. We compared 38812 patients with IBD to ageand sex-matched non-IBD controls with a ratio of 1:*** newly diagnosed with ESRD were identified with the ICD-10 *** During a mean follow-up of 4.9 years, ESRD was detected in 79(0.2%) patients with IBD and 166(0.1%)controls. The incidence of ESRD in patients with IBD was0.42 per 1000 person-years. Patients with IBD had a significantly higher risk of ESRD than controls [adjusted hazard ratio(HR) = 3.03; 95% confidence interval(CI):1.77-5.20; P < 0.001]. The incidences(per 1000 personyears)of ESRD were 0.51 in patients with CD and 0.13 in controls, respectively(adjusted HR = 6.33; 95%CI:2.75-14.56; P < 0.001). In contrast, the incidence of ESRD was similar between the UC and control groups(0.37 vs 0.37 per 1000 person-years; adjusted HR = 2.01;95%CI: 0.90-4.51; P = 0.089).CONCLUSION The risk of ESRD was elevated in patients with CD, but not UC. Patients with CD should be monitored carefully for signs of renal insufficiency.

关键词： Claims data Inflammatory bowel disease Crohn’s disease End-stage renal disease Ulcerative colitis

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Pregnancy Outcomes at Kasungu Maternity Ward in Central Malawi—A Review of Maternity Ward Register

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Advances in Reproductive Sciences 2019年第3期7卷 51-59页

作者： Joo Heon park Jin Sik Song James G. Kim changhyun Han Diane J. Moon Byungchan Kim James Kachingwe George Talama Youth with Talents Fairfax VA USA The Gwinnett School of Mathematics Science and Technology Lawrenceville GA USA Biomedical Engineering Washington University St. Louis MO USA Kasungu District Hospital Kasungu Malawi

Health care services during pregnancy and childbirth and after delivery are important for the survival and wellbeing of both the mother and the infant. The pregnancy outcomes at Kasungu District Hospital Maternity Ward have not been documented. Additionally, MDHS does not capture data regarding, prematurity, APGAR scores, and causes of maternal deaths and causes of neonatal deaths. Using Kasungu District Hospital Maternity Ward register, we aimed to describe the pregnancy outcomes at Kasungu Maternity Ward. From March 2016 to February 2017, data were available for 10,842 deliveries. The calculated Perinatal Mortality Rate (PMR) was about 77/1000 births and the Maternal Mortality Ratio (MMR) was 318 deaths per 100,000 live births. The Spontaneous Vertex Delivery (SVD) rate was 86% and the caesarean section rate was 10%. 1734 (16%) of all deliveries were premature borne between 28 and 36 gestation weeks. 1182 (11%) deliveries had missing APGAR scores and 81 neonates were born with 5 min Apgar scores less than 7. Adverse pregnancy outcomes occur at Kasungu Hospital Maternity Ward. More effort and resources are needed to decrease their occurrence.

关键词： Pregnancy Outcomes Mode of Delivery Perinatal Deaths Stillbirths Maternal Deaths APGAR Scores

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