检索结果-南通市图书馆

Huoxue Jiedu Huayu recipe(活血解毒化瘀方)inhibits macrophage-secreted vascular endothelial growth factor-a on angiogenesis and alleviates renal fibrosis in the contralateral kidneys of unilateral ureteral obstruction rats

引用

Journal of Traditional Chinese Medicine 2024年第3期44卷 458-467页

作者： gao Xiaomeng QIANG Panpan chang Jingyue FAN Lili YANG Fan XU Qingyou Graduate School Hebei University of Chinese MedicineHebei Key Laboratory of Integrative Medicine on Liver-Kidney PatternsHebei University of Chinese MedicineShijiazhuang 050091China Graduate School Hebei University of Chinese MedicineHebei Key Laboratory of Integrative Medicine on Liver-Kidney PatternsHebei University of Chinese MedicineInstitute of Integrative MedicineHebei University of Chinese MedicineShijiazhuang 050091China

OBJECTIVE:To elucidate the mechanism by which Huoxue Jiedu Huayu recipe(活血解毒化瘀方,HJHR)regulates angiogenesis in the contralateral kidney of unilateral ureteral obstruction(UUO)rats and the mechanism by which it reduces of renal ***:Male Wistar rats were randomly divided into 4 groups:the sham group,UUO group(180 d of left ureter ligation),UUO plus eplerenone(EPL)group,and UUO plus HJHR *** 180 d of oral drug administration,blood and contralateral kidneys were collected for ***-and fibrosis-related indexes were ***:HJHR and EPL improved structural damage and renal interstitial fibrosis in the contralateral kidney and reduced the protein expression levels ofα-smooth muscle actin(α-SMA),vimentin and collagen ***,these treatments could reduce the expression of vascular endothelial growth factor-A(VEGFA)by inhibiting the infiltration of ***,HJHR and EPL significantly reduced the expression of CD34 and CD105 by downregulating VEGFA production,which inhibited ***,the coexpressions of CD34,CD105 andα-SMA were decreased in the HJHR and EPL groups,indicating that endothelial-to-mesenchymal transition was ***:These findings confirm that HJHR alleviates contralateral renal fibrosis by inhibiting VEGFAinduced angiogenesis,encourage the use of HJHR against renal interstitial fibrosis and provide a theoretical basis for the clinical management of patients with CKD.

关键词： epithelial-mesenchymal transition aldosterone eplerenone receptors mineralocorticoid unilateral ureteral obstruction Huoxue Jiedu Huayu recipe

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

退化草甸植物根系生产力对不同恢复措施的响应

引用

Journal of Plant Ecology 2024年第3期17卷 141-152页

作者： Meng Cui Hong-Hui Wu chang-Qing Jing Tao Zhang Shi-Ying Zhao Ying-Zhi gao Key Laboratory of Grassland Resources and Ecology of Xinjiang Uygur Autonomous Region College of Grassland ScienceXinjiang Agricultural UniversityUrumqi 830052China State Key Laboratory of Vegetation and Environmental change Institute of Botanythe Chinese Academy of SciencesBeijing 100093China State Key Laboratory of Effcient Utilization of Arid and Semi-arid Arable Land in Northern China Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Arable Land Quality Monitoring and Evaluation Ministry of Agriculture and Rural AffairsInstitute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Vegetation Ecology of the Ministry of Education Jilin Songnen Grassland Ecosystem National Observation and Research StationNortheast Normal UniversityChangchun 130024China Songyuan Agriculture and Rural Bureau Songyuan 138000China

根系生产力及其动态变化对评价退化草地的恢复起着重要作用。然而,目前尚不清楚根系如何响应不同恢复措施。为了探究根系对不同恢复措施的响应,本研究于2013–2014年在退化草甸开展了田间试验。试验处理包括:自由放牧(FG)、不翻耕(NP)... 详细信息

根系生产力及其动态变化对评价退化草地的恢复起着重要作用。然而,目前尚不清楚根系如何响应不同恢复措施。为了探究根系对不同恢复措施的响应,本研究于2013–2014年在退化草甸开展了田间试验。试验处理包括:自由放牧(FG)、不翻耕(NP)、仅翻耕(OP)、翻耕+施肥(PF)、翻耕+覆盖(PM)和翻耕+施肥+覆盖(PFM)。研究结果表明,根系的季节动态为单峰模式,主要受降水的影响,但不受恢复措施的影响。不同恢复措施对根系生产力的影响取决于降水量。在2013年,与FG相比,PFM通过增加ANPP、土壤含水量和根系数量显著提高根系生产力达242.34%(0–10 cm)和90.8%(10–20 cm);2014年不同恢复措施对根系生产力的影响不显著。根系周转在不同恢复措施间无显著变化,其范围为0.47–0.78 yr−1。这主要是由于在不同样地中优势物种均是一年生物种虎尾草(Chloris virgata),其根系周转变化相对较小。此外,PFM还通过改善土壤条件提高了根系寿命和存活率。上述结果表明,组合恢复措施是促进松嫩草甸地下根系恢复的有效途径。

关键词：恢复措施退化草甸根系生产力根系周转根系寿命

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Exploration of the coupled lattice Boltzmann model based on a multiphase field model:A study of the solid-liquid-gas interaction mechanism in the solidification process

引用

Chinese Physics B 2024年第3期33卷 638-648页

作者：朱昶胜王利军高梓豪刘硕李广召 College of Computer and Communication Lanzhou University of TechnologyLanzhou 730050China State Key Laboratory of Gansu Advanced Processing and Recycling of Non-Ferrous Metal Lanzhou University of TechnologyLanzhou 730050China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China

A multiphase field model coupled with a lattice Boltzmann(PF-LBM)model is proposed to simulate the distribution mechanism of bubbles and solutes at the solid-liquid interface,the interaction between dendrites and bubbles,and the effects of different temperatures,anisotropic strengths and tilting angles on the solidified organization of the SCN-0.24wt.%butanedinitrile alloy during the solidification *** model adopts a multiphase field model to simulate the growth of dendrites,calculates the growth motions of dendrites based on the interfacial solute equilibrium;and adopts a lattice Boltzmann model(LBM)based on the Shan-Chen multiphase flow to simulate the growth and motions of bubbles in the liquid phase,which includes the interaction between solid-liquid-gas *** simulation results show that during the directional growth of columnar dendrites,bubbles first precipitate out slowly at the very bottom of the dendrites,and then rise up due to the different solid-liquid densities and pressure *** bubbles will interact with the dendrite in the process of flow migration,such as extrusion,overflow,fusion and *** the case of wide gaps in the dendrite channels,bubbles will fuse to form larger irregular bubbles,and in the case of dense channels,bubbles will deform due to the extrusion of *** the simulated region,as the dendrites converge and diverge,the bubbles precipitate out of the dendrites by compression and diffusion,which also causes physical phenomena such as fusion and spillage of the *** results reveal the physical mechanisms of bubble nucleation,growth and kinematic evolution during solidification and interaction with dendrite growth.

关键词： multiphase field model lattice Boltzmann model(LBM) Shan-Chen multiphase flow solidification organization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluation of the famous classic formula Sanhua decoction based on network pharmacology and multi-component quantitative analysis

引用

Traditional Medicine Research 2024年第1期9卷 1-13页

作者： Xin Zhang Wan-Cui Wang Jin-Kui Zhang Wei-Mei Zhang Peng-Wang Wang Peng-Cheng Lin Yong-chang Lu Xia Li Wen-Yuan gao College of Pharmacy Qinghai Minzu UniversityXining 810000China Qinghai Key Laboratory of Phytochemistry on Qinghai-Tibet Plateau Qinghai Minzu UniversityXining 810000China School of Pharmaceutical Science and Technology Tianjin UniversityTianjin 300000China Qinghai Engineering Technology Research Center of Modern Tibetan Medicine Creation Qinghai Minzu UniversityXining 810000China

Background:Sanhua decoction has significant effects in the treatment of *** study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal pieces and the substance ***:Network pharmacology was employed to investigate the potential active components and molecular mechanisms of Sanhua decoction in the treatment of stroke.15 batches of Sanhua decoction lyophilized powder were prepared using traditional formulas and subjected to high-performance liquid chromatography analysis to generate fingerprints of the Sanhua decoction substance ***,a multi-component quantitative analysis method was established,allowing for the simultaneous determination of ten components,to study the transfer of quantity values between pieces and substance ***:60 active ingredients were screened from Sanhua decoction by network pharmacology,of which gallic acid,magnolol honokiol,physcion,and aloe-emodin may have a greater effect than other active components.63 key targets and 134 pathways were predicted as the potential mechanism of Sanhua decoction in treating *** fingerprint similarity of the Sanhua decoction substance benchmarks was found to be good among the 15 batches,confirming the 19 common *** content of the 10 components was basically *** components’transfer rates were within 30%of their respective ***:This study provided a comprehensive and reliable strategy for the quality evaluation of Sanhua decoction substance benchmarks and held significant importance in improving its application value.

关键词： Sanhua decoction classic famous formula HPLC fingerprinting value transfer network pharmacology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes

引用

Nuclear Science and Techniques 2024年第4期35卷 208-220页

作者： Ao-Yan Cheng Hao Cai Shi Chen Tian-Lu Chen Xiang Dong you-Liang Feng Qi gao Quan-Bu Gou Yi-Qing Guo Hong-Bo Hu Ming-Ming Kang Hai-Jin Li Chen Liu Mao-Yuan Liu Wei Liu Fang-Sheng Min Chu-Cheng Pan Bing-Qiang Qiao Xiang-Li Qian Hui-Ying Sun Yu-chang Sun Ao-Bo Wang Xu Wang Zhen Wang Guang-Guang Xin Yu-Hua Yao Qiang Yuan Yi Zhang School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan UniversityKunming 650091China Ministry of Education The Key Laboratory of Cosmic Rays(Tibet University)Lhasa 850000China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences 19 A Yuquan RoadShijingshan DistrictBeijing 100049China College of Physics Sichuan UniversityChengdu 610064China School of Intelligent Engineering Shandong Management UniversityJinan 250357China Tsung‑Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China Suzhou Aerospace Information Research Institute Suzhou 215123China College of Physics Chongqing UniversityNo.55 Daxuecheng South RoadHigh‑tech DistrictChongqing 401331China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210008China

The High Altitude Detection of Astronomical Radiation(HADAR)experiment,which was constructed in Tibet,China,combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity advantages of focused Cherenkov *** objective is to observe transient sources such as gamma-ray bursts and the counterparts of gravitational *** study aims to utilize the latest AI technology to enhance the sensitivity of HADAR *** datasets and models with distinctive creativity were constructed by incorporating the relevant physical theories for various *** models can determine the type,energy,and direction of the incident particles after careful *** obtained a background identification accuracy of 98.6%,a relative energy reconstruction error of 10.0%,and an angular resolution of 0.22°in a test dataset at 10 *** findings demonstrate the significant potential for enhancing the precision and dependability of detector data analysis in astrophysical *** using deep learning techniques,the HADAR experiment’s observational sensitivity to the Crab Nebula has surpassed that of MAGIC and *** energies below 0.5 TeV and remains competitive with conventional narrow-field Cherenkov telescopes at higher *** addition,our experiment offers a new approach for dealing with strongly connected,scattered data.

关键词： VHE gamma-ray astronomy HADAR Deep learning Convolutional neural networks

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A study on the application of diffuse axonal multi-axis general evaluation for braininjury assessment in small overlap barrier crash test

引用

Chinese Journal of Traumatology 2024年第4期27卷 200-210页

作者： Zhi Fu Yi chang Tao Xiong Wen-Kai gao Kui Li Yu Liu China Automotive Engineering Research Institute Co. Ltd.Chongqing401122China Chongqing University of Technology Chongqing400054China Chongqing Key Laboratory of Vehicle Crash/Bio-Impact and Traffic Safety Chongqing400042China College of Medical Informatics Chongqing Medical UniversityChongqing400016China

Purpose:Head injury criterion(HIC)companied by a rotation-based metric was widely believed to behelpful for head injury prediction in road traffic ***,the Euro-New Car AssessmentProgram utilized a newly developed metric called diffuse axonal multi-axis general evaluation(DAMAGE)to explain test device for human occupant restraint(THOR)head injury,which demonstratedexcellent ability in capturing concussions and diffuse axonal ***,there is still a lack ofcomprehensive understanding regarding the effectiveness of using DAMAGE for Hybrid III 50thpercentile male dummy(H50th)head injury *** objective of this study is to determinewhether the DAMAGE could capture the risk of H50th brain injury during small overlap barrier ***:To achieve this objective,a total of 24 vehicle crash loading curves were collected as input datafor the multi-body *** commercially available mathematical dynamic models,namelyH50th and THOR,were utilized to investigate the differences in head injury ***,adecision method known as simple additive weighting was employed to establish a comprehensive braininjury metric by incorporating the weighted HIC and either DAMAGE or brain injury ***,35 sets of vehicle crash test data were used to analyze these brain injury ***:The rotational displacement of the THOR head is significantly greater than that of the *** maximum linear and rotational head accelerations experienced by H50th and THOR modelswere(544.6±341.7)m/s^(2),(2468.2±1309.4)rad/s^(2) and(715.2±332.8)m/s^(2),(3778.7±1660.6)rad/s^(2),*** the same loading condition during small overlap barrier(SOB)tests,THOR exhibits ahigher risk of head injury compared to the H50th *** was observed that the overall head injuryresponse during the small overlap left test condition is greater than that during the small overlap ***,an equation was formulated to establis

关键词： Diffuse axonal multi-axis general evaluation Head injury criterion Head injury assessment Small overlap barrier Biomechanical response

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Polyvinyl alcohol fiber cement-stabilized macadam:A review and performance evaluation

引用

Journal of Traffic and Transportation Engineering(English Edition) 2024年第3期11卷 406-423页

作者： Chaohui Wang Jikang Liu Shaochang Chen Feng Chen Zhiwei gao School of Highway Chang'an UniversityXi'an 710064China Shaanxi Transportation Technology Consulting Co. Ltd.Xi'an 710068China School of Information Engineering Xizang Minzu UniversityXianyang 712082China

This review evaluated research results on polyvinyl alcohol fiber cement-stabilized macadam(PVA-FCSM)to further improve the long-term durability of road structures and promote its in-depth study and high-quality *** suitable PVA fiber technical indexes for ordinary cement-stabilized macadam(CSM)were *** difference in the mechanical properties between CSM and PVA-FCSM was *** extent to which PVA fibers enhance the durability of CSM were ***,the mechanism of enhancement of CSM by PVA fibers was ***,the performance of each type of fiber cement-stabilized macadam(FCSM)was compared and *** results indicated that the suggested PVA fiber length and content for CSM were 12-30 mm and 0.6-1.2 kg/m^(3),*** different ages,the mean degree of improvement in the unconfined compressive strength was 14%,20%,and 14%,that in the compressive resilience modulus was 8%,11%,and 6%,and that in the splitting strength was 29%,15%,and 22%,*** different ages,the mean degree of decreased in the dry shrinkage coefficient was 21%,16%,and 15%and that in the temperature shrinkage coefficient(20℃-30℃)was 23%,23%,and 18%,*** coefficients increased with extended curing ***,at the same stress level,PVA-FCSM has a higher fatigue life compared to *** bridging effect,high strength,and high modulus of PVA fiber enhance the strength and anti-cracking of *** recommended fiber type for CSM is PVA fiber.

关键词： Highway and railway engineering PVA fiber cement-stabilized macadam Mechanical performance Durability Enhancement mechanism Performance valuation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unraveling the efficacy network: A network meta-analysis of adjuvant external beam radiation therapy methods after hepatectomy

引用

World Journal of Gastrointestinal Surgery 2024年第1期16卷 205-214页

作者： gao-Yuan Yang Zhi-Wei He Yong-chang Tang Feng Yuan Ming-Bo Cao Yu-Peng Ren Yu-Xuan Li Xiao-Rui Su Zhi-Cheng Yao Mei-Hai Deng Department of Hepatobiliary Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of General Surgery Qilu HospitalShandong UniversityJinan 250012Shandong ProvinceChina Department of General Surgery The First Affiliated HospitalGuangzhou Medical UniversityGuangzhou 511436Guangdong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Primary liver cancer is a malignant tumor with a high recurrence rate that significantly affects patient *** adjuvant external radiation therapy(RT)has been shown to effectively prevent recurrence after liver cancer ***,there are multiple RT techniques available,and the differ-ential effects of these techniques in preventing postoperative liver cancer re-currence require further *** To assess the advantages and disadvantages of various adjuvant external RT methods after liver resection based on overall survival(OS)and disease-free survival(DFS)and to determine the optimal *** This study involved network meta-analyses and followed the PRISMA *** data of qualified studies published before July 10,2023,were collected from PubMed,Embase,the Web of Science,and the Cochrane *** included relevant studies on postoperative external beam RT after liver resection that had OS and DFS as the primary *** magnitudes of the effects were determined using risk ratios with 95%confidential *** results were analyzed using R software and STATA *** A total of 12 studies,including 1265 patients with hepatocellular carcinoma(HCC)after liver resection,were included in this *** was no significant heterogeneity in the direct paired comparisons,and there were no significant differences in the inclusion or exclusion criteria,intervention measures,or outcome indicators,meeting the assumptions of heterogeneity and *** analysis revealed that patients who underwent stereotactic body radiotherapy(SBRT)after resection had longer OS than those who underwent intensity modulated radiotherapy(IMRT)or 3-dimensional conformal RT(3D-CRT).DFS analysis revealed that patients who underwent 3D-CRT after resection had the longest *** who underwent IMRT after resection had longer OS than those who underwent 3D-CRT and longer DFS than those who underwent ***

关键词： Primary liver cancer Hepatocellular carcinoma Network meta-analysis External beam radiation therapy Stereotactic body radiotherapy Intensity modulated radiotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

二氧化钒在太赫兹超材料中的研究进展

引用

硅酸盐学报 2024年第7期52卷 2371-2380页

作者：高敏罗毅恒路畅林媛电子科技大学材料与能源学院成都610054

超材料具有在亚波长尺度下操控电磁波的能力,近年来,通过对光场、电场、机械或温度场动态调控可以改变其光学特性的主动式超材料受到了广泛的研究。二氧化钒具有在68℃的临界温度下从低温绝缘相转变为高温金属相的特性,其电导率能够实现... 详细信息

超材料具有在亚波长尺度下操控电磁波的能力,近年来,通过对光场、电场、机械或温度场动态调控可以改变其光学特性的主动式超材料受到了广泛的研究。二氧化钒具有在68℃的临界温度下从低温绝缘相转变为高温金属相的特性,其电导率能够实现4~5个数量级的变化,将二氧化钒与超材料相互结合,能够满足可调谐性、高调制深度、多种调谐手段等优点。本文从二氧化钒的相变特性出发,归纳总结了二氧化钒在太赫兹超材料中的不同应用方向,主要包括可调谐太赫兹超材料吸波器、太赫兹调制器、太赫兹波前调控器以及可编程超材料,最后讨论了二氧化钒在太赫兹超材料应用中所面临的挑战和未来的发展方向。

关键词：超材料二氧化钒相变材料可调谐

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Composition design and performance evaluation of rubber-particle cement-stabilized gravel

引用

Frontiers of Structural and Civil Engineering 2024年第9期18卷 1466-1477页

作者： Chaohui WANG Ke YI Feng CHEN Luqing LIU Xiaolei ZHOU Zhiwei gao School of Highway Chang’an UniversityXi’an 710064China Shaanxi Transportation Technology Consulting Co. Ltd.Xi’an 710068China School of Information Engineering Xizang Minzu UniversityXianyang 71208China

To improve the mechanical properties and durability of the cement-stabilized base,rubber particles of three different sizes and with three different contents were optimally selected,the evolution laws of the mechanical strength and toughness of rubber-particle cement-stabilized gravel(RCSG)under different schemes were determined,and the optimal particle size and content of rubber particles were *** this basis,the durability of the RCSG base was *** results show that with an increase in the rubber particle size and content,the mechanical strength of RCSG gradually decreased,whereas the toughness and transverse deformation ability gradually increased.1%content and 2–4 mm sized RCSG can better balance the relationship between mechanical strength and *** 7 d unconfined compressive strength was 17.7%higher than that of the 4–8 mm *** 28 d toughness index and ultimate splitting strain can be increased by 9.8%and 6.3 times,respectively,compared with ordinary cement-stabilized gravel(CSG).In terms of durability,compared with CSG,RCSG showed a 3.7%increase in the water stability property of cement-stabilized base with 1%content and 2–4 mm rubber particles,5.5%increase in the frozen coefficient,and 80.6%and 37.9%increase in the fatigue life at 0.70 and 0.85 stress ratio levels,respectively.

关键词： pavement materials cement-stabilized gravel rubber particles material components mechanical property durability performance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：