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Nitric Oxide Signaling Molecules in Acupoints:Toward Mechanisms of Acupuncture

Chinese Journal of Integrative Medicine 2017年第11期23卷 812-815页

作者： ma sheng-xing Los Angeles Biomedical Research Institute at Harbor-UCLAMedical Center and Department of Obstetrics and Gynecology David Geffen School of MedicineUniversity of California at Los Angeles and Harbor-UCLA Medical CenterTorranceCA(90502)United States

Recent clinical trial studies have demonstrated that the effects of acupuncture on pain improvement are small and no difference between acupoints and non-points. Whether acupuncture needles must be inserted in specific points depends on whether acupoint specificity exists that is still not resolved, and is now urgent. Previous anatomical studies have demonstrated that acupoints exist higher number of nerve fibers/trunks, blood vessels, hair follicles, and sweat glands as well as density of the gap junction. Recent evidence shows that nitric oxide（NO） level is elevated in the acupoints/meridians and is associated with an enhanced expression of NO synthase endowed with transient receptor potential vanilloid type-1. There is growing evidence from international groups showing that acupuncture induces NO-mediated vasodilatation, which increases local blood flow and allows for a flush of algesic or sensitizing substances, leading to pain relief. Previous studies, using a novel biocapture system, have demonstrated that NOx–（total nitrite and nitrate） and cyclic guanosine monophosphate（c GMP） concentrations are consistently increased over skin acupoints compared to non-meridian control regions（NMCR） in humans. Dermal microdialysis in humans showed that NO-c GMP releases in the subcutaneous tissue of acupoint are higher than those in NMCR and increased by electroacupuncture（EA）. Recent studies have demonstrated that low-frequency electrical stimulation and manual acupuncture with low stimulating force and rate produce an elevation of NO release predominantly over acupoints. In contrast, NO levels over the areas of the skin regions are moderately reduced by high-frequency EA stimulation. The results from anatomical and biochemical studies consistently show that acupoints exist higher levels of NO signaling molecules, and stimulus-evoked NO release is also with a higher level at acupoints. Results suggest that NO signaling molecules contribute to the specificity of acupoints,

关键词： acupoint nitric oxide electroacupuncture manual acupuncture reinforcement methods

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Baishideng's century goal:Editing and publishing high-quality articles

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World Journal of Gastroenterology 2009年第31期15卷 3841-3844页

作者： Lian-sheng ma Beijing Baishideng BioMed Scientific Co. Ltd. Room 903 Building D Ocean International Center No. 62 Dongsihuan Zhonglu Chaoyang District Beijing 100025 China

Baishideng's goal over the next few years is to edit and publish high-quality articles through the open-access model, to maximize the benefits to members of the editorial board, authors and readers, as well as achievi... 详细信息

关键词： Access to information Baishideng maximization of the personal benefit Editorial policies Open access Periodicals Publishing

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The law of barrel wear and its application

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Defence Technology（防务技术） 2018年第6期14卷 674-676页

作者： Ji-sheng ma School of Mechanical Engineering Xijing University

A power function relation between number of rounds and barrel wear amount is created based on the test data from firing of large-caliber barrels. The function is optimized to fully fit the test data. A new concept of diameter change rate of bore is proposed and the law of barrel wear is put forward by means of comparing the diameter change rates for large-caliber barrels with different calibers. It is shown that the law of barrel wear is successful in barrel life prediction.

关键词： Barrel life Prediction model Law of barrel wear Curve fitting

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Properties of Nonlinear Transverse-Electric Waves in a Two-Core Optical Waveguide with a Nonlinear Cladding

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Chinese Physics Letters 1998年第7期15卷 501-503页

作者： ma Chun-sheng Department of Electronic Engineering National Integrated Optoelectronics LaboratoryJilin UniversityChangchun 130023

Expressions of dispersion relation and propagation power are presented for the nonlinear transverse-electric(TE)waves in a two-core optical waveguide with a nonlinear *** properties of the nonlinear TE waves are *** is found that when the total core thickness and the distance between the two cores are sufficiently large,the power curves of the higher odd modes become very sharp in some narrow ranges of the effective refractive index,compared with those of the higher even modes.

关键词： Nonlinear nonlinear adding

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Development of Novel Supported Gold Catalysts： A materials Perspective

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Nano Research 2011年第1期4卷 3-32页

作者： Zhen ma sheng Dai Department of Environmental Science and Engineering Fudan University Shanghai 200433 China Chemical Sciences Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA

Since Haruta et al. discovered that small gold nanoparticles finely dispersed on certain metal oxide supports can exhibit surprisingly high activity in CO oxidation below room temperature, heterogeneous catalysis by supported gold nanoparticles has attracted tremendous attention. The majority of publications deal with the preparation and characterization of conventional gold catalysts （e.g., Au/TiO2）, the use of gold catalysts in various catalytic reactions, as well as elucidation of the nature of the active sites and reaction mechanisms. In this overview, we highlight the development of novel supported gold catalysts from a materials perspective. Examples, mostly from those reported by our group, are given concerning the development of simple gold catalysts with single metal-support interfaces and heterostructured gold catalysts with complicated interfacial structures. Catalysts in the first category include active Au/SiO2 and Au/metal phosphate catalysts, and those in the second category include catalysts prepared by pre-modification of supports before loading gold, by post-modification of supported gold catalysts, or by simultaneous dispersion of gold and an inorganic component onto a support. CO oxidation has generally been employed as a probe reaction to screen the activities of these catalysts. These novel gold catalysts not only provide possibilities for applied catalysis, but also furnish grounds for fundamental research.

关键词： Gold nanoparticles catalyst design catalyst support functionalization promotion CO oxidation

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A learning framework based on weighted knowledge transfer for holiday load forecasting

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Journal of Modern Power Systems and Clean Energy 2019年第2期7卷 329-339页

作者： Pan ZENG chang sheng Min JIN College of Computer Science and Electronic Engineering Hunan University

Since the variation pattern of load during holidays is different than that of non-holidays, forecasting holiday load is a challenging task. With a focus on this problem, we propose a learning framework based on weighted knowledge transfer for daily peak load forecasting during ***,we select source cities which can provide extra hidden knowledge to improve the forecast accuracy of the load of the target city. Then, all the instances which are from source cities and the target city will be weighted and trained by the improved weighted transfer learning algorithm which is based on the TrAdaBoost algorithm and can decrease negative transfer. We evaluate our method with the classical support vector machine method and a method based on knowledge transfer on a real data set, which includes eleven cities in Guangdong province of China,to illustrate the performance of the method. To solve the problem of limited historical holiday load data, we transfer the data from nearby cities based on the fact that nearby cities in Guangdong province of China have a similar economic development level and similar load variation pattern. The results of comparative experiments show that the framework proposed by this paper outperforms these methods in terms of mean absolute percent error and mean absolute scaled error.

关键词： Load forecasting Holiday effect Sparse data Weighted knowledge transfer

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Synthesis and Characterization of Zirconia Nanocrystallites by Cationic Surfactant and Anionic Surfactant

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Chinese Journal of Structural Chemistry 2005年第10期24卷 1133-1139页

作者： YU Jian-chang HU sheng-Wei College of material Science and Engineering Fuzhou University Fuzhou 350002 China

Study on nanomaterials has attracted great interests in recent years. In this article, zirconia nanocrystallites of different structures have been successfully synthesized via hydrothermal methods with cationic surfactant （CTAB） and anionic surfactant （SDS）, respectively. Differential Scanning Calorimeter （DSC-TG）, X-ray Diffractometer （XRD）, Transmission Electron Microscope （TEM）, Ultraviolet-Visible （UV-vis） and N2 adsorption-desorption analyses are used for their structure characteristics. The results show that the cationic surfactant has a distinctive direction effect on the formation of zirconia nanocrystallites, while the anionic surfactant has a self-assembly synergistic effect on them. The sample synthesized with the cationic surfactant presents good dispersion with the main phase of tetragonal zirconia, and the average nanocrystal size is around 15 nm after calcination at 500 ℃. While the sample synthesized with the anionic surfactant exhibits a worm-like mesoporous structure with pure tetragonal phase after calcination at 500 ℃ and with good thermal stability.

关键词： cationic surfactant anionic surfactant zirconia nanocrystallites,mesoporous zirconia

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Genesis of geothermal water in the hinterland of Guanzhong Basin， China: Insight from hydrochemical and isotopic analysis

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Journal of Earth Science 2025年

作者： Jiangxia Wang Panpan Xu Hui Qian Yongqi Zang Qiming Wang Zhiyuan ma School of Water and Environment， chang'an University Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region of the Ministry of Education， chang'an University Key Laboratory of Eco-hydrology and Water Security in Arid and Semi-arid Regions of Ministry of Water Resources， chang'an University

The Guanzhong Basin， located in Shaanxi Province， China， has abundant geothermal resources in its hinterland. Focusing on typical thermal reservoir structural units， namely the Xianli fault-step (XL) and Xi'an depression (XA)， this study reveals the genesis of geothermal water by combining hydrochemistry and environmental isotopes. The geothermal waters of XL uniformly correspond to the Na-Cl type with high contents of major ions， while the geothermal water of XA has complex hydrochemical types. The quartz geothermometer (with maximum steam loss) and Na-K-Ca geothermometer are recommended for XL and the quartz geothermometer (with no and maximum steam loss) and Na-K geothermometer for XA. Their temperature ranges are 99-159℃ and 93-146℃， respectively. The circulation depth of geofluids in XL and XA range from 2579 to 4766 m and from 2541 to 4330 m， with mean apparent ages of 21543 and 20345 yr B.P.， respectively. The geothermal water in XL originates from a mixture of sedimentary water and ancient infiltration water， and its formation mode was the vertical heat conduction with cooling process. In contrast， the geothermal water in XA originates from the dual process of cooling and mixing， with the process being dominated by ancient infiltration water and supplementation by modern infiltration water.

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Three-dimensional multi-phase-field simulation of eutectoid alloy based on OpenCL parallel

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China Foundry 2021年第3期18卷 239-248页

作者： chang-sheng Zhu Yu-jie Li Fang-lan ma Li Feng Peng Lei School of Computer and Communication Lanzhou University of TechnologyLanzhou 730050China State Key Laboratory of Gansu Advanced Processing and Recycling of Non-Ferrous Metal Lanzhou University of TechnologyLanzhou 730050China School of materials Science and Engineering Lanzhou University of TechnologyLanzhou 730050China

Seeking high-performance computing methods to solve the problem of a large amount of calculation,low calculation efficiency,and small simulation scale on the traditional single central processing unit (CPU) platform is of great value to the simulation study of *** this study,based on the three-dimensional multi-phase-field model of KKSO coupling phase-field and solute field,the open computing language (OpenCL) + graphics processing unit (GPU) heterogeneous parallel computing technology is used to simulate the eutectoid growth of Fe-C alloy and the end growth process of pearlite under pure *** effects of initial supercooling and different diffusion coefficients on the growth morphology of lamellar pearlite were *** results show that ferrite and cementite are perpendicular to the front of the solid-solid interface and are coupled and coordinated to grow,and there is no leading phase under the initial supercooling degree of 20 *** the continuous increase of the initial supercooling degree (19 K-22 K),the morphology changes of the eutectoid layer are as follows:cementite stops growing → slice amplitude increases → regular symmetric growth → oblique growth → layer *** the increase of the diffusion coefficient from 3×10^(-13) m^(2)·s^(-1) to 15×10^(-13) m^(2)·s^(-1),the growth rate of the microstructure of the lamellar pearlite increases linearly,and there is no obvious change in the frontal appearance of the pearlite.

关键词： phase-field model lamellar pearlite eutectoid phase transition OpenCL Fe-C alloy

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Efficient parallel adaptive array beamforming algorithm

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Journal of Systems Engineering and Electronics 2009年第6期20卷 1221-1226页

作者： Huang Fei sheng Weixing ma Xiaofeng Dept. of Communication Engineering Nanjing Univ. of Science and Technology Nanjing 210094 P. R. China

For a large-scale adaptive array, the heavy computational load and the high-rate data transmission are two challenges in the implementation of an adaptive digital beamforming system. An efficient parallel digital beamforming （DBF） algorithm based on the least mean square algorithm （PLMS） is proposed. An appropriate method is found to partition the least mean square （LMS） algorithm into a number of operational modules, which can be easily executed in a distributed-parallel-processing fashion. As a result, the proposed PLMS algorithm provides an effective solution that can alleviate the bottleneck of high-rate data transmission and reduce the computational cost. PLMS requires less computational load than that of the conventional parallel algorithms based on the recursive least square （RLS） algorithm, as well as it is easier to be implemented to do real time adaptive array processing. Moreover, low sidelobe of the beam pattern is obtained by constraining the static steering vector with Tschebyscheff coefficients. Finally, a scheme of the PLMS algorithm using distributed-parallel-processing system is also proposed. The simulation results demonstrate that the PLMS algorithm has the same interference cancellation performance as that of the conventional LMS algorithm. Moreover, the PLMS algorithm can obtain the same good beamforming performance, regardless how the algorithm is partitioned. It is expected that the proposed algorithm will be used in a large-scale adaptive array system to deal with real time adaptive digital beamforming processing.

关键词： adaptive digital beamforming parallel algorithm least mean square generalized sidelobe canceller.

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