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Asian Pacific Journal of Tropical Biomedicine 2019年第2期9卷 53-59页

作者： Da Eun Kim Yeon Sil Hwang Bo yoon chang Dae Sung Kim Hyoung Kwon Cho Sung Yeon Kim Institute of Pharmaceutical Research and Development College of PharmacyWonkwang University Hanpoong Pharm.CO. Ltd

Objective: To investigate cosmetic potential of Syzygium aromaticum L.(S. aromaticum L.) and to determine its antioxidant and anti-wrinkling effects. Methods: Using highperformance liquid chromatography, eugenol component was quantitated. The antioxidant activity of S. aromaticum L. was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging and superoxide dismutase like activities. To determine cell viability, elastase and matrix metalloproteinase-1(MMP-1) activity, human dermal fibroblasts(HS68) were treated with S. aromaticum L. The inhibitory effect of S. aromaticum L. on tumor necrosis factor alpha induced MMPs expression in HS68 was analyzed by realtime-PCR. Results: The eugenol content was confirmed in S. aromaticum L. S. aromaticum L. was observed to have high 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity and superoxide dismutase like activity. S. aromaticum L. had no cytotoxicity against the HS68 and dose-dependently increased elastase inhibition. Moreover, S. aromaticum L. significantly decreased MMP-1 content and inhibited gene levels of MMP-1, MMP-2, MMP-3 and MMP-9. Conclusions: The findings suggest that S. aromaticum L. has great potential as a cosmeceutical ingredient with antioxidant and antiwrinkling effects.

关键词： Syzygium aromaticum L Antioxidant Anti-aging Elastase Matrix metalloproteinase-1

Boron nitride for enhanced oxidative dehydrogenation of ethylbenzene

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Journal of Energy Chemistry 2021年第6期30卷 477-484,I0012页

作者： Rui Han Jiangyong Diao Sonu Kumar Andrey Lyalin Tetsuya Taketsugu Gilberto Casillas Christopher Richardson Feng Liu chang Won yoon Hongyang Liu Xudong Sun Zhenguo Huang Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) Northeastern UniversityShenyang 110819LiaoningChina School of Civil and Environmental Engineering University of Technology SydneyUltimoNew South Wales 2007Australia Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina Institute for Chemical Reaction Design and Discovery(WPI-ICReDD) Hokkaido UniversitySapporo 001-0021Japan Center for Green Research on Energy and Environmental Materials National Institute for Materials Science(NIMS)Tsukuba 305-0044Japan Department of Chemistry Faculty of ScienceHokkaido UniversitySapporo 060-0810Japan Electron Microscopy Centre University of WollongongNew South Wales 2500Australia Molecular Horizons and School of Chemistry and Molecular Bioscience Faculty of ScienceMedicine and HealthUniversity of WollongongNew South Wales 2522Australia Center for Hydrogen and Fuel Cell Research Korea Institute of Science and TechnologySeoul 02792Republic of Korea

It is demonstrated experimentally and confirmed theoretically that highly defective boron nitride showed outstanding performance for oxidative dehydrogenation of *** catalyst is derived from carbon-doped hexagonal boron nitride nanosheets synthesized via a two-step reaction when participating the oxidative dehydrogenation *** first step yields a polymeric precursor with the atomic positions of B,C,N relatively constrained,which is conducive for the formation of carbon atomic clusters uniformly dispersed throughout the BN *** the oxidative dehydrogenation of ethylbenzene to styrene,the nanoscale carbon clusters are removed and highly defective boron nitride(D-BN)is obtained,exposing boron-rich zigzag edges of BN that act as the catalytic *** catalytic performance of D-BN is therefore remarkably better than un-doped *** results indicate that dispersed C-doping in h-BN is highly effective in terms of defect formation and resultant enhanced activity in oxidative dehydrogenation reactions.

关键词： Boron nitride Dehydrogenation Ethylbenzene Carbon-doping Heterogeneous catalysis

Non-surgical treatment of post-surgical bile duct injury: Clinical implications and outcomes

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World Journal of Gastroenterology 2014年第22期20卷 6924-6931页

作者： Young Ook Eum Joo Kyung Park Jaeyoung Chun Sang-Hyub Lee Ji Kon Ryu Yong-Tae Kim Yong-Bum yoon chang Jin yoon Ho-Seong Han Jin-Hyeok Hwang Department of Internal medicine Cheongju St. Mary's HospitalChungcheongbuk-do 360-568South Korea Department of Internal Medicine Seoul National University Hospital Seoul National University College of Medicine Seoul 110-744South Korea Department of Internal Medicine Seoul National University College of Medicine Seoul National University bundang Hospital Gyeonggi-do 463-707South Korea Department of Radiology Seoul National University Bundang HospitalGyeonggi-do 463-707South Korea Department of Surgery Seoul National University Bundang HospitalGyeonggi-do 463-707South Korea

AIM: To investigate the prognostic factors determining the success rate of non-surgical treatment in the management of post-operative bile duct injuries (BDIs).

关键词： Endoscopic retrograde cholangiography Percutaneous transhepatic cholangiography Percutaneous transhepatic biliary drainage Bile duct Biliary stricture.

Effect of change of sand properties on travel distance of ricocheted debris

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Defence Technology（防务技术） 2021年第4期17卷 1486-1495页

作者： yoon Keon Kim Woo Chun Choi Department of Mechanical Engineering Korea University145 Anam-roSeongbuk-guSeoul02841Republic of Korea

The debris from exploded buildings can ricochet after colliding with the ground,thus increasing the debris travel distance and danger from any associated impacts or *** reduce this danger,the travel distance of ricocheted debris must be accurately *** study analyzed the change in the travel distance of ricocheted concrete debris relative to changes in the properties of a sand *** shear tests were conducted to measure the change in internal friction angle as a function of temperature and water content of the *** element analysis(FEA)was then applied to these variables to predict the speed and angle of the debris after *** FEA results were compared with results of low-speed ricochet experiments,which employed variable temperature and water *** travel distance of the debris was calculated using MATLAB,via trajectory equations considering the drag *** the internal friction angle decreased,the shear stress decreased,leading to deeper penetration of the debris into the *** the loss of kinetic energy increased,the velocity and travel distance of the ricocheted debris *** in the ricochet velocity and travel distance of the debris,according to changes in the internal friction angle,indicated that the debris was affected by the environment.

关键词： Ricochet Exploded debirs Environmental change Sand Temperature Water content Internal friction angle Travel distance

Embolization of pancreatic arteriovenous malformation:A case report

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World Journal of Clinical Cases 2020年第8期8卷 1471-1476页

作者： So Yeon yoon Gyeong Sik Jeon Shin Jae Lee Dae Joong Kim chang Il Kwon Mi Hyun Park Department of Radiology CHA Bundang Medical CenterCollege of MedicineCHA UniversitySeongnam-si 13496Gyeonggi-doSouth Korea Department of Radiology Research Institute of Radiological ScienceYongin Severance HospitalYonsei University College of MedicineYongin-si 17046South Korea Department of Internal Medicine Digestive Disease CenterCHA Bundang Medical CenterCollege of MedicineCHA UniversitySeongnam-si 13496Gyeonggi-doSouth Korea Department of Radiology Dankook University HospitalChungcheongnam-do 31116South Korea

BACKGROUND Pancreatic arteriovenous malformation(AVM)is a rare disease with a number of different reported treatment methods,but there are as yet no established or definite treatments for the *** SUMMARY A 43-year-old man visited the hospital due to periumbilical *** patient underwent imaging study and laboratory testing for evaluation of *** AVM associated with pancreatitis was suspected on computed tomography and magnetic resonance *** patient was diagnosed with pancreatic AVM with pancreatitis on imaging study and *** arterial embolization with various embolic materials was ***-up computed tomography scan revealed progressive regression of AVM and improvement of *** two-year follow-up,the patient showed no recurrence of symptom or *** Transcatheter arterial embolization can be considered an effective treatment modality for selective cases of pancreatic AVM.

关键词： Pancreas Arteriovenous malformation Pancreatitis Pancreatic pseudocyst Embolization Therapeutic Case report

Short-term and long-term outcomes of laparoscopic vs open ileocolic resection in patients with Crohn's disease: Propensityscore matching analysis

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World Journal of Gastroenterology 2021年第41期27卷 7159-7172页

作者： Shin Jeong Pak Young Il Kim Yong Sik yoon Jong Lyul Lee Jung Bok Lee chang Sik Yu Department of Colon and Rectal Surgery University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Clinical Epidemiology and Biostatistics University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND Laparoscopic ileocolic resection(LICR)is the preferred surgical approach for primary ileocolic Crohn’s disease(CD)because it has greater recovery benefits than open ICR(OICR).AIM To compare short-and long-term outcomes in patients who underwent LICR and *** Patients who underwent ICR for primary CD from 2006 to 2017 at a single tertiary center specializing in CD were *** who underwent LICR and OICR were subjected to propensity-score matching *** were propensityscore matched 1:1 by factors potentially associated with 30-d perioperative *** included demographic characteristics and disease-and treatment-related *** were compared using univariate and multivariate ***-term surgical recurrence-free survival(SRFS)in the two groups was determined by the Kaplan-Meier method and compared by the log-rank *** During the study period,348 patients underwent ICR,211 by the open approach and 137 ***-score matching yielded 102 pairs of *** rate of postoperative complication was significantly lower(14%versus 32%,P=0.003),postoperative hospital stay significantly shorter(8 d versus 13 d,P=0.003),and postoperative pain on day 7 significantly lower(1.4 versus 2.3,P<0.001)in propensity-score matched patients who underwent LICR than in those who underwent *** analysis showed that postoperative complications were significantly associated with preoperative treatment with biologics[odds ratio(OR):3.14,P=0.01]and an open approach to surgery(OR:2.86,P=0.005).The 5-and 10-year SRFS rates in the matched pairs were 92.9%and 83.3%,respectively,with SRFS rates not differing significantly between the OICR and LICR *** performance of additional procedures was an independent risk factor for surgical recurrence[hazard ratio(HR):3.28,P=0.02].CONCLUSION LICR yielded better short-term outcomes and postoperative recovery than OICR,with no differences in long-ter

关键词： Crohn’s disease Laparoscopic Surgery Postoperative complications Recurrence Propensity score Retrospective study

Parameterization of below-cloud scavenging for polydisperse fine mode aerosols as a function of rain intensity

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Journal of Environmental Sciences 2023年第10期132卷 43-55页

作者： chang Hoon Jung Hyung-Min Lee Dasom Park Young Jun yoon Yongjoo Choi Junshik Um Seoung Soo Lee Ji Yi Lee Yong Pyo Kim Department of Health Management Kyungin Women’s UniversityIncheon 21041Korea Department of Environmental Science and Engineering Ewha Woman’s UniversitySeoulKorea Department of Environmental Engineering Konkuk UniversitySeoulKorea Korea Polar Research Institute IncheonKorea Department of Environment Hankuk University of Foreign StudiesYonginKorea Department of Atmospheric Sciences Pusan National UniversityBusanKorea Earth System Science Interdisciplinary Center University of MarylandCollege ParkMDUSA Research Center for Climate Sciences Pusan National UniversityBusanKorea Department of Chemical Engineering and Materials Science Ewha Womans UniversitySeoulKorea

The below-cloud aerosol scavenging process by precipitation is one of the most important mechanisms to remove aerosols from the *** to its complexity and dependence on both aerosol and raindrop sizes,wet scavenging process has been poorly treated,especially during the removal of fine *** makes the numerical simulation of below-cloud scavenging in large-scale aerosolmodels *** consider the slip effects of submicron particles,a simplified expression for the diffusion scavenging was developed by approximating the Cunningham slip correction *** derived analytic solution was parameterized as a simple power function of rain intensity under the assumption of the lognormal size distribution of *** resultant approximated expression was compared to the observed data and the results of previous studies including a 3D atmospheric chemical transport model *** with the default GEOS-Chem coefficient of 0.00106R0.61 and the observation-based coefficient of 0.0144R0.9268,the coefficient of a and b in∧m=aRb spread in the range of 0.0002-0.1959 for a and 0.3261-0.525 for b over a size distribution of GSD of 1.3–2.5 and a geometric mean diameter of 0.01-2.5μ***,this study showed that the scavenging coefficient varies widely by orders of magnitude according to the size distribution of particles and rain *** study also demonstrated that the obtained simplified expression could consider the theoretical approach of aerosol *** proposed analytic approach showed that results can be effectively applied for reduced computational burden in atmospheric modeling.

关键词： Below-cloud scavenging Polydisperse aerosol Parameterization Cunningham correction factor Scavenging coefficient

Surgical outcomes of Korean ulcerative colitis patients with and without colitis-associated cancer

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World Journal of Gastroenterology 2015年第12期21卷 3547-3553页

作者： Yong Sik yoon Yong Beom Cho Kyu Joo Park Seung Hyuk Baik Sang Nam yoon Seung-Bum Ryoo Kil Yeon Lee Hungdai Kim Ryung-Ah Lee chang Sik Yu Department of Colon and Rectal Surgery University of Ulsan College of Medicine and Asan Medical Center epartment of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine Department of Surgery Seoul National University College of Medicine Department of Surgery Yonsei University College of Medicine Severance Hospital Department of Surgery Kangnam Sacred Heart Hospital Hallym University College of Medicine Department of Surgery Kyung Hee University School of Medicine Department of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Department of Surgery Ewha Womans University School of Medicine

AIM: To determine the clinicopathologic characteristics of surgically treated ulcerative colitis(UC) patients, and to compare the characteristics of UC patients with colitis-associated cancer(CAC) to those without CAC. METHODS: Clinical data on UC patients who underwent abdominal surgery from 1980 to 2013 were collected from 11 medical institutions. Data were analyzed to compare the clinical features of patients with CAC and those of patients without ***: Among 415 UC patients, 383(92.2%) underwent total proctocolectomy, and of these, 342(89%) were subjected to ileal pouch-anal anastomosis. CAC was found in 47 patients(11.3%). Adenocarcinoma was found in 45 patients, and the others had either neuroendocrine carcinoma or lymphoma. Comparing the UC patients with and without CAC, the UC patients with CAC were characteristically older at the time of diagnosis, had longer disease duration, underwent frequent laparoscopic surgery, and were infrequently given preoperative steroid therapy(P < 0.001-0.035). During the 37 mo mean follow-up period, the 3-yearoverall survival rate was 82.2%.CONCLUSION: Most Korean UC patients experience early disease exacerbation or complications. Approximately 10% of UC patients had CAC, and UC patients with CAC had a later diagnosis, a longer disease duration, and less steroid treatment than UC patients without CAC.

关键词： Ulcerative colitis Colorectal neoplasms Colorectal

Convergence of Stereo Vision-Based Multimodal YOLOs for FasterDetection of Potholes

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Computers, Materials & Continua 2022年第11期73卷 2821-2834页

作者： Sungan yoon Jeongho Cho Department of Electrical Engineering Soonchunhyang UniversityAsan31538Korea

Road potholes can cause serious social issues,such as unexpected damages to vehicles and traffic *** efficient road management,technologies that quickly find potholes are required,and thus researches on such technologies have been conducted *** three-dimensional(3D)reconstruction method has relatively high accuracy and can be used in practice but it has limited application owing to its long data processing time and high sensor maintenance *** two-dimensional(2D)vision method has the advantage of inexpensive and easy application of ***,although the 2D vision method using the convolutional neural network(CNN)has shown improved pothole detection performance and adaptability,large amount of data is required to sufficiently train the ***,we propose a method to improve the learning performance of CNN-based object detection model by artificially generating synthetic data similar to a pothole and enhancing the learning ***,to make the defective areas appear more contrasting,the transformed disparity map(TDM)was calculated using stereo-vision cameras,and the detection performance of the model was further improved through the late fusion with RGB(Red,Green,Blue)***,through the convergence of multimodal You Only Look Once(YOLO)frameworks trained by RGB images and TDMs respectively,the detection performance was enhanced by 10.7%compared with that when using only ***,the superiority of the proposed method was confirmed by showing that the data processing speed was two times faster than the existing 3D reconstruction method.

关键词： CNN YOLO disparity map stereo vision pothole

Turning an FDA-approved therapeutic into an AIEgen for imaging live bacteria and for bacterial detection

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Aggregate

Aggregate 2021年第2期2卷 1-2页

作者： Juyoung yoon Department of Chemistry and Nanoscience Ewha Womans UniversitySeoulRepublic of Korea

Aggregation Induced Emission(AIE)is an attractive,fluorescent-based phenomenon that can be used to design fluorescent imaging agents and fluorescent *** this highlight,we discuss a recently reported study that identifies the chemical scaffold of an FDA-approved therapeutic(deferasirox)as a molecule with AIE-like properties(AIEgen).Utilizing its therapeutic efficacy for bacterial biofilms,deferasiroxderivatives were shown able to treat and image bacteria biofilms and detect a bacterial *** demonstrates the potential of AIE for drug design as this allows the simultaneous ability to image the therapeutic’s location and mode of action.

关键词： Aggregation-Induced Emission Antimicrobials Fluorescence imaging and Theranostics