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Do brood parasitic Common Cuckoos develop brood patches during the breeding season?

Avian Research 2024年第3期15卷 363-368页

作者： jun-Seo Go Hae-Ni Kim Sue-Jeong Jin Myeong-Chan Cha Heesoo lee Jin-Won lee Korea Institute of Ornithology&Department of Biology Kyung Hee University02447SeoulRepublic of Korea Bird Research SaeZiP 12504YangpyeongRepublic of Korea

Many birds develop brood patches on their ventral apterium under hormonal regulation to effectively transmit body heat to eggs during *** developed patch has several characteristics,including de-feathering,vascularization,and ***,little is known about whether avian brood parasites that do not incubate their eggs exhibit brood patch development during the breeding *** this study,we measured the size of the ventral apterium in 114 Common Cuckoos(Cuculus canorus)captured in the field throughout the breeding season and examined the appearance of the ventral apterium to confirm the development of brood *** also examined whether morphological traits and various factors correlated with the size of the ventral apterium(sternal apterium and abdominal apterium)and how it changed during the breeding *** found no clear signs of brood patch development in Common Cuckoos captured throughout the breeding season,indicating that they likely did not develop brood patches on the ventral apterium during this *** also found that ventral apterium size was positively correlated with wing length and body *** addition,Common Cuckoos with newly growing feathers on the boundary of the ventral apterium with pteryla were frequently observed as seasons progressed to the *** conclusion,Common Cuckoos exhibit neither brood patch development nor the vestigial characteristics of ancestral brood patches,except for the growth of feathers on boundary the ventral *** studies examining brood patches across different groups of avian brood parasites are valuable for enhancing our understanding of the developmental and physiological adaptations of avian brood parasites.

关键词： Brood parasitism Brood patch Common Cuckoo Pterylosis Re-feathering Ventral apterium

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Trends in colorectal cancer incidence according to an increase in the number of colonoscopy cases in Korea

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 51-60页

作者： Ga Hee Kim Yeong Chan lee Tae jun Kim Sung Noh Hong Dong Kyung chang Young-Ho Kim Dong-Hoon Yang chang Mo Moon Kyunga Kim Hyun Gun Kim Eun-Ran Kim Division of Gastroenterology Department of Internal MedicineAsan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Digital Health Samsung Advanced Institute for Health Science and TechnologySungkyunkwan University School of MedicineSeoul 06351South Korea Division of Gastroenterology Department of Internal MedicineSamsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Division of Gastroenterology Department of Internal MedicineEwha Womans UniversitySeoul 07985South Korea Biomedical Statistics Center Samsung Medical CenterSeoul 06351South Korea Division of Gastroenterology Department of Internal MedicineSoonchunhyang University College of MedicineSeoul 04401South Korea

BACKGROUND The incidence of colorectal cancer(CRC)and preinvasive CRC(e.g.,early colon cancer and advanced adenoma)is gradually increasing in several *** To evaluate the trend in incidence of CRC and preinvasive CRC according to the increase in the number of colonoscopies performed in *** This retrospective cohort study enrolled Korean patients from 2002 to 2020 to evaluate the incidence of CRC and preinvasive CRC,and assess the numbers of diagnostic colonoscopies and colonoscopic ***-related complications by age group were also *** The incidence of CRC showed a rapid increase,then decreased after 2012 in the 50-75 year-age *** the study period,the rate of incidence of preinvasive CRC increased at a similar level in patients under 50 and 50-75 years of *** 2009,the increase has been rapid,showing a pattern similar to the increase in *** rate of colonoscopic polypectomy in patients aged under 50 was similar to the rate in patients over 75 years of age after *** rate of complications after colonoscopy and related deaths within 3 mo was high for those over 75 years of *** The diagnosis of preinvasive CRC increased with the increase in the number of colonoscopies *** the risk of colonoscopy-related hospitalization and death is high in the elderly,if early lesions at risk of developing CRC are diagnosed and treated under or at the age of 75,colonoscopy-related complications can be reduced for those aged 76 years or over.

关键词： Colorectal cancer Preinvasive colorectal cancer Colorectal polypectomy Colonoscopy

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A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 593-631页

作者： Nilkanth Mukund Deshpande Shilpa Gite Biswajeet Pradhan Abdullah Alamri chang-Wook lee Department of Electronics&Telecommunication LavaleSymbiosis Institute of TechnologySymbiosis International(Deemed University)PuneMaharashtra412115India Electronics&Telecommunication Dr.Vithalrao Vikhe Patil College of EngineeringAhmednagarMaharashtra414111India Artificial Intelligence and Machine Learning Department Symbiosis Institute of TechnologySymbiosis International(Deemed)UniversityPune412115India Symbiosis Centre of Applied AI(SCAAI) Symbiosis International(Deemed)UniversityPune412115India Centre for AdvancedModelling and Geospatial Information Systems(CAMGIS) School of Civil and Environmental EngineeringFaculty of Engineering&ITUniversity of Technology SydneySydneyAustralia Earth Observation Centre Institute of Climate ChangeUniversiti Kebangsaan MalaysiaBangiSelangor43600Malaysia Department of Geology&Geophysics College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia Department of Science Education Kangwon National UniversityChuncheon-si24341Korea

Infection of leukemia in humans causes many complications in its later *** impairs bone marrow’s ability to produce *** diagnosis of human blood cells is a well-known and well-proven technique for diagnosis in this *** binary classification is employed to distinguish between normal and leukemiainfected *** addition,various subtypes of leukemia require different *** sub-classes must also be detected to obtain an accurate diagnosis of the type of *** entails using multi-class classification to determine the leukemia *** is usually done using a microscopic examination of these blood *** to the requirement of a trained pathologist,the decision process is critical,which leads to the development of an automated software framework for *** utilized state-of-the-art machine learning approaches,such as Support Vector Machine(SVM),Random Forest(RF),Na飗e Bayes,K-Nearest Neighbor(KNN),and others,to provide limited accuracies of *** advanced deep-learning methods are also *** to constrained dataset sizes,these approaches result in over-fitting,reducing their outstanding *** study introduces a deep learning-machine learning combined approach for leukemia *** uses deep transfer learning frameworks to extract and classify features using state-of-the-artmachine learning *** transfer learning frameworks such as VGGNet,Xception,InceptionResV2,Densenet,and ResNet are employed as feature *** extracted features are given to RF and XGBoost classifiers for the binary and multi-class classification of leukemia *** the experimentation,a very popular ALL-IDB dataset is used,approaching a maximum accuracy of 100%.A private real images dataset with three subclasses of leukemia images,including Acute Myloid Leukemia(AML),Chronic Lymphocytic Leukemia(CLL),and Chronic Myloid Leukemia(CML),is also employed to generalize the *** d

关键词： Leukemia diagnosis deep learning machine learning random forest XGBoost

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Insect-specific RNA virus affects the stylet penetration activity of brown citrus aphid(Aphis citricidus)to facilitate its transmission

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Insect Science 2024年第1期31卷 255-270页

作者： Xin An Qiaoying Gu Jing Wang Tengyu chang Wei Zhang Jin-jun Wang Jinzhi Niu Key Laboratory of Entomology and Pest Control Engineering College of Plant ProtectionAcademy of Agricultural ScienceSouthwest UniversityChongqingChina

Sap-sucking insects often transmit plant viruses but also carry insect viruses,which infect insects but not *** impact of such insect viruses on insect host biology and ecology is largely ***,we identified a novel insect-specific virus carried by brown citrus aphid(Aphis citricidus),which we tentatively named Aphis citricidus picornavirus(AcPV).Phylogenetic analysis discovered a monophyletic cluster with AcPV and other unassigned viruses,suggesting that these viruses represent a new family in order *** infection with AcPV triggered aphid antiviral immunity mediated by RNA interference,resulting in asymptomatic ***,we found that AcPV was transmitted horizontally by secretion of the salivary gland into the feeding sites of *** influenced aphid stylet behavior during feeding and increased the time required for intercellular penetration,thus promoting its transmission among aphids with plants as an intermediate *** gene expression results suggested that this mechanism was linked with transcription of salivary protein genes and plant defense hormone ***,our results show that the horizontal transmission of AcPV in brown citrus aphids evolved in a manner similar to that of the circulative transmission of plant viruses by insect vectors,thus providing a new ecological perspective on the activity of insect-specific viruses found in aphids and improving the understanding of insect virus ecology.

关键词： electrical penetration graph feeding behavior insect virus transmission Picornavirales salivary protein

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Long non-coding RNA GATA6-AS1 is mediated by N6-methyladenosine methylation and inhibits the proliferation and metastasis of gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1019-1028页

作者： jun-Jie Shen Min-chang Li Shao-Qi Tian Wen-Ming Chen Department of Oncology Jiangxi Hospital of Integrated Chinese and Western MedicineNanchang 330000Jiangxi ProvinceChina Department of Hepatopancreatobiliary Surgery Jiangxi Hospital of Integrated Chinese and Western MedicineNanchang 330000Jiangxi ProvinceChina Clinical Medical School Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Oncology Jining No.1 People’s HospitalJining 272011Shandong ProvinceChina

BACKGROUND Through experimental research on the biological function of GATA6-AS1,it was confirmed that GATA6-AS1 can inhibit the proliferation,invasion,and migration of gastric cancer cells,suggesting that GATA6-AS1 plays a role as an anti-oncogene in the occurrence and development of gastric *** experi-ments confirmed that the overexpression of fat mass and obesity-associated protein(FTO)inhibited the expression of GATA6-AS1,thereby promoting the occurrence and development of gastric *** To investigate the effects of GATA6-AS1 on the proliferation,invasion and migration of gastric cancer cells and its mechanism of *** We used bioinformatics methods to analyze the Cancer Genome Atlas(https://***/.The Cancer Genome Atlas)and download expression data for GATA6-AS1 in gastric cancer tissue and normal *** also constructed a GATA6-AS1 lentivirus overexpression vector which was transfected into gastric cancer cells to investigate its effects on proliferation,migration and invasion,and thereby clarify the expression of GATA6-AS1 in gastric cancer and its biological role in the genesis and development of gastric ***,we used a database(http://***/starbase2/)to analysis GATA6-AS1 whether by m6A methylation modify regulation and predict the methyltransferases that may methylate ***,RNA immunoprecipitation experiments confirmed that GATA6-AS1 was able to bind to the m6A methylation modification *** data allowed us to clarify the ability of m6A methylase to influence the action of GATA6-AS1 and its role in the occurrence and development of gastric *** Low expression levels of GATA6-AS1 were detected in gastric *** also determined the effects of GATA6-AS1 overexpression on the biological function of gastric cancer ***6-AS1 had strong binding ability with the m6A demethylase FTO,which was expressed at high levels in gastric cancer and negatively correlat

关键词： Long non-coding RNA GATA6-AS1 N6-methyladenine modification Fat mass and obesity-associated protein Gastric cancer

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Solid-state lithium-ion batteries for grid energy storage:opportunities and challenges

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Science China Chemistry 2024年第1期67卷 43-66页

作者： Xin chang Yu-Ming Zhao Boheng Yuan Min Fan Qinghai Meng Yu-Guo Guo Li-jun Wan CAS Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular SciencesBeijing National Laboratory for Molecular Sciences(BNLMS)Institute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China

The energy crisis and environmental pollution drive more attention to the development and utilization of renewable *** the capricious nature of renewable energy resource,it has difficulty supplying electricity directly to consumers stably and efficiently,which calls for energy storage systems to collect energy and release electricity at peak *** to their flexible power and energy,quick response,and high energy conversion efficiency,lithium-ion batteries stand out among multiple energy storage technologies and are rapidly deployed in the *** superior performance and ensuring the safety of energy storage systems,intrinsically safe solid-state electrolytes are expected as an ideal alternative to liquid *** this review,we systematically evaluate the priorities and issues of traditional lithium-ion batteries in grid energy *** lithium-ion batteries containing liquid electrolytes,solid-state lithium-ion batteries have the potential to play a more significant role in grid energy *** challenges of developing solid-state lithium-ion batteries,such as low ionic conductivity of the electrolyte,unstable electrode/electrolyte interface,and complicated fabrication process,are discussed in ***,the safety of solid-state lithium-ion batteries is *** the obtained insights,inspiring prospects for solid-state lithium-ion batteries in grid energy storage are depicted.

关键词： lithium-ion batteries grid energy storage solid-state electrolytes interface stability

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Effect of solute Ce,Mn,and Si on mechanical properties of silicon steel:insights from DFT calculations

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Journal of Iron and Steel Research International 2024年第3期31卷 700-709页

作者： Xiang-jun Liu Ji-chun Yang Hui-ping Ren Xiao-bin Jia Ming-yi Zhang chang-qiao Yang School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Key Laboratory of Integrated Exploitation of Bayan Obo Multi-Metal Resource Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina Inner Mongolia North Heavy Industries Group Co. Ltd.Baotou 014010Inner MongoliaChina Inner Mongolia Metal Material Research Institute Baotou 014010Inner MongoliaChina

The influence of solute Ce,Mn,and Si on the mechanical properties of silicon steel was investigated by first-principles ***,Mn,and Si can all be solubilized in Fe *** significantly reduces the incompressibility and rigidity of the system but also significantly improves the toughness and *** effect of Mn on mechanical properties of the system is not *** has a significant effect on the improvement in incompressibility and rigidity but a limited effect on the improvement in toughness and *** metallic bond strength of Fe-Ce,Fe-Mn,and Fe-Si doped systems is weaker than that of the pure Fe system,which can be used to explain the reduction in the incompressibility and rigidity of these doped *** relatively high electron cloud density in the doped system may be responsible for the increase in toughness.

关键词： Silicon steel Rare earth First-principles calculation Elastic modulus Electronic structure

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A dose-dependent bimodal switch by homologous Aux/IAA transcriptional repressors

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Molecular Plant 2024年第9期17卷 1407-1422页

作者： Hyung-Taeg Cho Minsu lee Hee-Seung Choi Kwang-Ho Maeng Kyeonghoon lee Ha-Yeon lee Anindya Ganguly Hoonyoung Park chang-Hoi Ho Department of Biological Sciences Seoul National UniversitySeoulKorea School of Earth and Environmental Sciences Seoul National UniversitySeoulKorea Department of Climate and Energy Systems Engineering Ewha Womans UniversitySeoulKorea

Combinatorial interactions between different regulators diversify and enrich the chance of transcriptional regulation in eukaryotic ***,a dose-dependent functional switch of homologous transcriptional repressors has rarely been ***,we show that SHY2,an auxin/indole-3-acetic acid(Aux/IAA)repressor,exhibits a dose-dependent bimodal role in auxin-sensitive root-hair growth and gene transcrip-tion in Arabidopsis,whereas other Aux/lAA homologs consistently repress the auxin *** co-repressor(TOPLESS[TPL])-binding affinity of a bimodal Aux/IAA was lower than that of a consistently re-pressing Aux/*** switch of a single amino acid residue in the TPL-binding motif between the bimodal form and the consistently repressing form switched their TPL-binding affinity and transcriptional and bio-logical roles in auxin *** on these data,we propose a model whereby competition between homologous repressors with different co-repressor-binding affinities could generate a bimodal output at thetranscriptional anddevelopmental levels.

关键词： auxin Aux/IAA dose-dependent regulation root hair transcription TOPLESS(TPL)

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Spatially distributed cytokinins:Metabolism,signaling,and transport

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Plant Communications 2024年第7期5卷 52-67页

作者： Jiangzhe Zhao Jingqi Wang Jie Liu Penghong Zhang Guzel Kudoyarova chang-jun Liu Kewei Zhang Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants College of Life SciencesZhejiang Normal UniversityJinhuaZhejiang 321004P.R.China Ufa Institute of Biology Ufa Federal Research CenterRASProspekt Oktyabrya 69Ufa 450054Russia Biology Department Brookhaven National LaboratoryUptonNY 11973USA

Cytokinins are mobile phytohormones that regulate plant growth,development,and environmental *** major cytokinin species include isopentenyl adenine(iP),trans-zeatin(tZ),cis-zeatin(cZ),and dihydrozeatin(DZ).The spatial distributions of different cytokinin species in different organelles,cells,tissues,and organs are primarily shaped by biosynthesis via isopentenyltransferases(IPT),cytochrome P450 monooxygenase,and 50-ribonucleotide phosphohydrolase and by conjugation or catabolism via glycosyltransferase or cytokinin oxidase/*** bind to histidine receptor kinases in the endoplasmic reticulum or plasma membrane and relay signals to response regulators in the nucleus via shuttle proteins known as histidine phosphotransfer *** movements of cytokinins from sites of biosynthesis to sites of signal perception usually require long-distance,intercellular,and intracellular *** the past decade,ATP-binding cassette(ABC)transporters,purine permeases(PUP),AZA-GUANINE RESISTANT(AZG)transporters,equilibrative nucleoside transporters(ENT),and Sugars Will Eventually Be Exported transporters(SWEET)have been characterized as involved in cytokinin transport *** review begins by introducing the spatial distributions of various cytokinins and the subcellular localizations of the proteins involved in their metabolism and *** focus on an inventory of the characterized transporters involved in cytokinin compartmentalization,including long-distance,intercellular,and intracellular transport,and the regulation of the spatial distributions of cytokinins by environmental *** directions for cytokinin research are also discussed.

关键词： cytokinin biosynthesis transporter signal transduction environmental changes

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Structural Properties of Ions and Polyelectrolytes in Aqueous Solutions under External Electric Fields:The Sign Effect

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Chinese Journal of Polymer Science 2024年第9期42卷 1341-1352,I0007页

作者： Cheng-Jiang Lin jun-jun Wang Yuan Jiang Shu-Li Chen Hong-Fei Li Wen-Han Zhao Qing-Rong Huang chang-Ru Rong Xiao-Zheng Duan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China National Key Laboratory of Advanced Vehicle Integration and Control China FAW Group Co.Ltd.Changchun130013China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200438China Department of Food Science Rutgers University65 Dudley RoadNew BrunswickNew Jersey08901USA

We utilize molecular dynamics simulations to investigate the microstructures of ions and polyelectrolytes in aqueous solutions under external electric *** focusing on the multi-body interactions between ionic components and H_(2)O molecules,as well as their responses to the external electric fields,we clarify several nontrivial molecular features of the ionic and polyelectrolyte solutions,such as the solvations of cations and anions,clustering of the ions,and dispersions/aggregations of polyelectrolyte chains,as well as the corresponding responses of H_(2)O molecules in these *** simulations illustrate the variations in structures of ionic solutions caused by reversing the charge sign of the ions,and elucidate the disparity in structures between anionic and cationic polyelectrolyte solutions in the presence of the external electric *** work clarifies the mechanism for the alternations in complex multi-body interactions in aqueous solutions caused by the application electric field,which can contribute to the fundamental understanding of the physical and chemical natures of ion-containing and charged polymeric systems.

关键词： Polyelectrolyte Ions Aqueous solutions External electric fields Asymmetric dipole

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