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Evaluation of the effect of partial splenic embolization on platelet values for liver cirrhosis patients with thrombocytopenia

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World Journal of Gastroenterology 2007年第4期13卷 619-622页

作者： Chi-Ming Lee Ting-Kai Leung Hung-Jung Wang Wei-Hsing Lee Li-kuo Shen Jean-Dean Liu Chun-Chao chang Ya-Yen Chen Department of Diagnostic Radiology Taipei Medical University Hospital Taipei Taiwan China Department of Medicine Taipei Medical University Taipei Taiwan China Department of Internal Medicine Taipei Medical University Hospital Taipei Taiwan China

AIM： TO investigate the effect of partial splenic embolization （PSE） on platelet values in liver cirrhosis patients with thrombocytopenia and to determine the effective embolization area for platelet values improvement.METHODS： Blood parameters and liver function indicators were measured on 10 liver cirrhosis patients （6 in Child-Pugh grade A and 4 in grade B） with thrombocytopenia （platelet values 〈 80 × 10^3/μL） before embolization. Computed tomography scan was also needed in advance to acquire the splenic baseline. After 2 to 3 d, angiography and splenic embolization were performed. A second computed tomography scan was made to confirm the embolization area after 2 to 3 wk of embolization. The blood parameters of patients were also examined biweekly during the 1 year follow-up period. RESULTS： According to the computed tomography images after partial splenic embolization, we divided all paUents into two groups： low （〈 30%）, and high （≥ 30%） embolization area groups. The platelet values were increased by 3 times compared to baseline levels after 2 wk of embolization in high embolization area group. In addition, there were significant differences in platelet values between low and high embolization area groups. GPT values decreased significantly in all patients after 2 wk of embolization. The improvement in platelet and GPT values still persisted until 1 year after PSE. In addition, 3 of 4 （75%） Child-Pugh grade B patients progressed to grade A after 2 mo of PSE. The complication rate in 〈 30% and ≥30% embolization area groups was 50% and 100%, respectively. CONCLUSION： Partial splenic embolization is an effective method to improve platelet values and GPT values in liver cirrhosis patients with thrombocytopenia and the ≥ 30% embolization area is meaningful for platelet values improvement. The relationship between the complication rate and embolization area needs further studies.

关键词： Partial splenic embolization Liver cirrhosis Thrombocytopenia

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Thermodynamic behaviors of Cu in interaction with chlorine, sulfur, phosphorus and minerals during sewage sludge co-incineration

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Chinese Journal of Chemical Engineering 2018年第5期26卷 1160-1170页

作者： Jingyong Liu Chao Liu Guang Sun Wuming Xie Xiao'e Dang Jiahong kuo Kenlin chang Jian Sun Shuiyu Sun Musa Buyukada Fatih Evrendilek School of Environmental Science and Engineering Institute of Environmental Health and Pollution Control Guangdong University of Technology Guangzhou 510006 China Shaanxi Key Laboratory for Gold and Resources School of Metallurgical Engineering Xi'an University of Architecture and Technology Xi'an 710055 China Institute of Environmental Engineering National Sun Yat-Sen University Kaohsiung 80424 China Department of Environmental Engineering Abant Izzet Baysal University Bolu 14052 Turkey

Thermodynamic equilibrium calculations were performed to reveal effects of interactions among Cl, S, P and other minerals on Cu migration. Our results showed that HCl（g）, SO2（g） and （P2O5）2（g） were released from the sewage sludge co-incineration. Cl was found to weaken adsorption of Cu by Al2O3, CaO and Fe2O3, while S de- layed reactions of Fe2O3 and Al2O3 with Cu, with P having no effect on reactions between the minerals and Cu. Among the coupled systems ofCl, S and P, the co-existences of Cl and S, and Cl, S and P were determined to inhibit Cu volatilization, and the co-existence of Cl and P had an enhancing effect Cu migration was affected only by S in the S and P system. With the SiO2, CaO and Al2O3 system, both Cl alone and Cl and P led to failed reactions be- tween the minerals and Cu. In the systems of S, S and Cl, S and P, and S, Cl and P, the migration behavior of Cu was mainly affected by S at low temperatures and by Cl at high temperatures, whereas P had no effect on Cu mi- gration during the entire nrocess.

关键词： Sewage sludge Incineration Cupper Thermodynamic equilibrium analysis

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A rare case of severe third degree friction burns and large Morel-Lavallee lesion of the abdominal wall

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Burns & Trauma 2018年第1期6卷 63-66页

作者： Darnell J.Brown kuo Jung G.Lu Kristina chang Jennifer Levin John T.Schulz Jeremy Goverman Massachusetts General Hospital Harvard Medical SchoolBostonMAUSA

Background: Morel-Lavallee lesions (MLLs) are rare internal degloving injuries typically caused by blunt traumatic injuries and most commonly occur around the hips and in association with pelvic or acetabular fractures. MLL is often overlooked in the setting of poly-trauma;therefore, clinicians must maintain a high degree of suspicion and be familiar with the management of such injuries, especially in obese poly-trauma patients. Case presentation: We present a 30-year-old female pedestrian struck by a motor vehicle who sustained multiple long bone fractures, a mesenteric hematoma, and full-thickness abdominal skin friction burn which masked a significant underlying abdominal MLL. The internal degloving caused significant devascularization of the overlying soft tissue and skin which required surgical drainage of hematoma, abdominal wall reconstruction with tangential excision, allografting, negative pressure wound therapy, and ultimately autografting. Conclusion: MLL is a rare, often overlooked, internal degloving injury. Surgeons must maintain a high index of suspicion when dealing with third degree friction burns as they may mask underlying injuries such as MLL, and a delay in diagnosis can lead to increased morbidity.

关键词： Friction burns Blunt trauma friction burns nternal degloving injuries Morel-Lavallee lesion Traumatic pseudocyst

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Prenatal glucocorticoid contributed to rat lung dysplasia is related to asymmetric dimethylarginine/nitric oxide pathway

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Science Bulletin 2015年第16期60卷 1416-1425页

作者： Yu-Chieh Chen Li-Tung Huang You-Lin Tain Chih-Cheng Chen Jiunn-Ming Sheen Mao-Meng Tiao Chih-Min Tsai Ho-chang kuo Chao-Cheng Huang Kow-Aung changDepartment of Anesthesiology chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science chang Gung University College of Medicine Hong-Ren Yu Department of Pediatrics Chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science Chang Gung University College of Medicine Department of Pathology Chang Gung Memorial Hospital-Kaohsiung Medical Center Graduate Institute of Clinical Medical Science Chang Gung University College of Medicine

Prenatal glucocorticoids （GCs） have been used to induce maturation of preterm fetal lungs and prevent the development of respiratory distress syndrome of the premature. Pulmonary surfactant induction has been regarded as the most important effect of prenatal GCs. However, report about the prolonged effects of prenatal GCs on the development of rat lung is of limited. In this study, we tried to investigate the acute and chronic modulation effects of prenatal dexamethasone （DEX） to asymmetric dimethylarginine （ADMA）/nitric oxide （NO） signal pathway of lung tissue. Pregnant Sprague Dawley rats at gestational day 14-20 were administered i.p. DEX （0.1 mg· kg-1 ·d-1）. Acute programming effects of prenatal DEX were assessed at postnatal day 7, and long-term programming effects of offspring were assessed at day 120. We found that repetitive prenatal DEX exposure contributes to DNA oxidative damage and alveolar tissue dysplasia. Prenatal DEX treatment decreased ADMA and increased iNOS expres- sion. Prenatal DEX treatment also increased TNF-α transcript expression and decreased HDAC2 protein expression at acute stage. In conclusion, repetitive prenatal DEX has prolonged stress damage effects on lung tissue.

关键词： Prenatal glucocorticoids ADMA DNA oxidative damage TNF-α HDAC2 Lung dysplasia

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温拌SBS改性再生沥青混合料的路用性能研究

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应用化工 2024年第5期53卷 1031-1035页

作者：田耀刚覃超张梦缘蒋静纪括齐琳张军长安大学材料科学与工程学院陕西西安710064 中国电建集团昆明勘测设计研究院有限公司云南昆明650051 长安大学公路养护装备国家工程实验室陕西西安710064

为研究再生SBS改性沥青混合料(RAP)掺量和温拌剂种类对温拌SBS改性再生沥青混合料的路用性能的影响,通过车辙试验、小梁弯曲试验和冻融劈裂试验分析了在RAP掺量为0,10%,30%,50%,Sasobit温拌剂掺量为3.0%和Evotherm温拌剂掺量为2.0%的温... 详细信息

为研究再生SBS改性沥青混合料(RAP)掺量和温拌剂种类对温拌SBS改性再生沥青混合料的路用性能的影响,通过车辙试验、小梁弯曲试验和冻融劈裂试验分析了在RAP掺量为0,10%,30%,50%,Sasobit温拌剂掺量为3.0%和Evotherm温拌剂掺量为2.0%的温拌SBS改性再生沥青混合料的高温稳定性能、低温抗裂性能和水稳性能,并通过灰色关联度分析RAP掺量对两种温拌再生沥青混合料路用性能的影响。结果表明,RAP的掺入可以极大地改善温拌再生沥青混合料的高温性能,但不利于其低温抗裂性能和水稳定性能。不同RAP掺量的沥青混合料对各项路用性能影响程度大小排序均为:水稳定性能<低温抗裂性能<高温稳定性能。在RAP掺量为30%时,掺入Evotherm温拌剂的再生沥青混合料的高温性能、低温抗裂性能、水稳定性能优于掺入Sasobit温拌剂的再生沥青混合料。

关键词：温拌再生沥青混合料废旧SBS改性沥青混合料路用性能温拌剂

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PHENOLIC COMPOUNDS PROMOTE HIGH EFFICIENCY TRANSFORMATION OF PLANT EXPLANTS in vitro BY Agrobacterium tumefaciens

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Chinese Science Bulletin 1989年第22期34卷 1902-1907页

作者：许耀贾敬芬郑国锠 Department of Biology. Lanzhou University Lanzhou 730000 PRC

The development of plant gene engineering requires a simple, rapid and efficient system for genetic transformation. It is recently demonstrated that certain compounds, secreted by host plant cells, are capable of eliciting the activation of Agrobacterium and Ti plasmid genes which are involved in promoting T-DNA transfer from the bacterium to the plant cell,

关键词： pbenollc compounds Vir-region activation in vitro transformation T-DNA transfer Agrobacterium tumefaciens

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Surfactant protein D inhibits lipid-laden foamy macrophages and lung inflammation in chronic obstructive pulmonary disease

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Cellular & Molecular Immunology 2023年第1期20卷 38-50页

作者： Miao-Hsi Hsieh Pei-Chi Chen Han-Yin Hsu Jui-chang Liu Yu-Sheng Ho Yuh Jyh Lin Chin-Wei kuo Wen-Shuo kuo Hui-Fang Kao Shulhn-Der Wang Zhi-Gang Liu Lawrence Shih-Hsin Wu Jiu-Yao Wang Center for Allergy Immunologyand Microbiome(A.I.M.)China Medical University HospitalTaichungTaiwanChina Graduate Institute of Basic Medical Sciences College of MedicineNational Cheng Kung UniversityTainanTaiwanChina Department of Nursing National Tainan Junior College of NursingTainanTaiwanChina Graduate Institute of Biochemistry and Molecular Biology College of MedicineNational Cheng Kung UniversityTainanTaiwanChina Department of Pediatrics National Cheng Kung University HospitalTainanTaiwanChina Division of Pulmonary Medicine Department of Internal MedicineNational Cheng Kung University HospitalCollege of MedicineNational Cheng Kung UniversityTainanTaiwanChina Institute of Clinical Medicine College of MedicineNational Cheng Kung UniversityTainanTaiwanChina School of Chemistry and Materials Science Nanjing University of Information Science and TechnologyNanjingChina School of Post-Baccalaureate Chinese Medicine China Medical UniversityTaichungTaiwanChina Department of Respirology and Allergy Third Affiliated Hospital of Shenzhen UniversityShenzhenChina Institute of Biomedical Sciences China Medical UniversityTaichungTaiwanChina Department of Allergy Immunologyand Rheumatology(AIR)China Medical University Children’s HospitalTaichungTaiwanChina

Increased levels of surfactant protein D (SP-D) and lipid-laden foamy macrophages (FMs) are frequently found under oxidative stress conditions and/or in patients with chronic obstructive pulmonary disease (COPD) who are also chronically exposed to cigarette smoke (CS). However, the roles and molecular mechanisms of SP-D and FMs in COPD have not yet been determined. In this study, increased levels of SP-D were found in the bronchoalveolar lavage fluid (BALF) and sera of ozone- and CS-exposed mice. Furthermore, SP-D-knockout mice showed increased lipid-laden FMs and airway inflammation caused by ozone and CS exposure, similar to that exhibited by our study cohort of chronic smokers and COPD patients. We also showed that an exogenous recombinant fragment of human SP-D (rfhSP-D) prevented the formation of oxidized low-density lipoprotein (oxLDL)-induced FMs in vitro and reversed the airway inflammation and emphysematous changes caused by oxidative stress and CS exposure in vivo. SP-D upregulated bone marrow-derived macrophage (BMDM) expression of genes involved in countering the oxidative stress and lipid metabolism perturbations induced by CS and oxLDL. Our study demonstrates the crucial roles of SP-D in the lipid homeostasis of dysfunctional alveolar macrophages caused by ozone and CS exposure in experimental mouse emphysema, which may provide a novel opportunity for the clinical application of SP-D in patients with COPD.

关键词： Alveolar macrophages Chronic obstructive pulmonary diseases Surfactant protein D Lipid metabolism Ozone Cigarettes

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Immobilization of cross-linked In-doped Mo(O,S)2 on cellulose nanofiber for effective organic-compound degradation under visible light illumination

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Progress in Natural Science:Materials International 2021年第3期31卷 404-413页

作者： Hairus Abdullah Chi-Ning Hsu Hardy Shuwanto Noto Susanto Gultom Worku Lakew Kebede chang-Mou Wu Chiu-Chun Lai Ri-Ichi Murakami Masayuki Hirota Antonio Norio Nakagaito Dong-Hau kuo Department of Materials Science and Engineering National Taiwan University of Science and Technology Department of Textile Engineering Chinese Culture University New Material Research & Development Department Frontier Materials Laboratories Osaka Gas Chemicals Co. Ltd. Graduate School of Technology Industrial and Social Sciences Tokushima University

Relatively small amounts of In-doped Mo(O,S)2(IMS) catalysts(10%, 20%, and 30%) were deposited on cellulose nanofiber(CNF) by cross-linking them with functional groups of siloxane and epoxy to form CNF-IMS hybrid composites. The as-prepared hybrid composites were characterized and tested their performances toward the photo degradations of cationic(MB and Rh B) and anionic(MO) dyes. As indium was doped into Mo(O,S)2lattice to form solid-solution, the charge transfer and photocarrier separation during the catalytic reaction were simultaneously enhanced as probed with electrochemical impedance spectroscopy and photoluminescence measurements, respectively. To ensure the catalyst on CNF was well deposited and recyclable, the hybrid composite was evaluated with a reusability experiment to show the stability performance in degrading organic dyes. It was found the environmentally friendly CNF-IMS hybrid composite was relatively stable during the reusability experiment, indicating no catalyst powder was leached out during the photocatalytic reaction. The photoreaction mechanism was convinced by radical-scavenging experiments to show that hydroxyl and superoxide played essential roles for the organic dye degradations in visible-light illuminated conditions. The cross-linked organic/inorganic hybrid catalyst showed a prospective visible light active material not only to solve the environmental issue due to the leaching of nanoparticles but also to lower the post-treatment/recycling cost of photocatalyst in industrial application.

关键词： Cellulose nanofiber In-doped Mo(O,S) 2 Cross-linking In 2 (O,S) 3 Organic dye degradation

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Adaptive WFM Filter with Noise Detection Capability

Adaptive WFM Filter with Noise Detection Capability

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1996 3rd International Conference on Signal Processing(ICSP’96)

作者： chang-Shing Lee Yau-Hwang kuo Institute of Information Engineering National Cheng Kung University

ISBN: (纸本)0780329120

＜正＞A new fuzzy filter for the removal of additive impulse noise,called Adaptive Weighted Fuzzy Mean（AWFM） filter,is proposed and analyzed in this *** AWFM is an extensive version of Weighted Fuzzy Mean（WFM） filter[1] and its filtered output signal is either the output of WFM or the processed signal decided by the detection *** filter gives better performance compared with conventional filters when evaluated by Mean Absolute Error（MAE）, Mean Square Error（MSE） and subjective evaluation *** dedicated hardware *** is also much simpler than the conventional median filter.

关键词： adaptive filters adaptive signal processing adaptive signal detection filtering theory median filters noise image processing fuzzy set theory noise detection adaptive WFM filter additive impulse noise removal adaptive weighted fuzzy mean filter weighted fuzzy mean filter filtered output signal detection algorithm filter performance mean absolute error mean square error MSE subjective evaluation dedicated hardware implementation median filter image processing fuzzy set theory image transmission experimental results

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Self-assembly of single metal sites embedded covalent organic frameworks into multi-dimensional nanostructures for efficient CO_(2) electroreduction

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Chinese Chemical Letters 2022年第3期33卷 1439-1444页

作者： Yi-Lu Yang Yi-Rong Wang Guang-kuo Gao Ming Liu chang Miao Le-Yan Li Wei Cheng Zi-Yue Zhao Yifa Chen Zhifeng Xin Shun-Li Li Dong-Sheng Li Ya-Qian Lan Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials Jiangsu Key Laboratory of New Power BatteriesSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjing 210023China School of Chemistry South China Normal UniversityGuangzhou 510006China Institute of Molecular Engineering and Applied Chemistry Anhui University of TechnologyMa'anshan 243002China College of Materials and Chemical Engineering Hubei Provincial Collaborative Innovation Center for New Energy MicrogridKey Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China

Morphology-controlled electrocatalysts with the ability of CO_(2) adsorption/activation, mass transfer, high stability and porosity are much desired in electrochemical CO_(2) reduction reaction (CO_(2)RR). Here, three kinds of multi-dimensional nanostructures (i.e., hollow sphere, nanosheets and nanofibers) have been successfully produced through the modulation of porphyrin-based covalent organic frameworks (COFs) with various modulators. The obtained nanostructures with high-stability, large surface-area, and single metal sites enable efficient CO_(2)RR into CH_(4). Notably, they all exhibit higher FE (hollow sphere, 68.2%;nanosheet, 64.2% and nanofiber, 71.0%, -0.9 V) than COF-366-Cu (43.0%, -0.9 V) after morphology control. Noteworthy, the FE of COF-366-Cu (HS) keeps higher than 52.4% over a wide potential range from -0.9 V to -1.1 V and the achieved FECH_(4) + C_(2)H_(4) (82.8%, -0.9 V) is superior to most of reported COFs and copper-based electrocatalysts. This work paves a new way in the exploration of COF-based multi-dimensional nanostructures applicable in efficient CO_(2)RR to CH_(4).

关键词： CO_(2)electroreduction Covalent organic frameworks Hollow sphere Nanofiber Nanosheet

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