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抗结核药物引起儿童肝损伤的危险因素分析

妇儿健康导刊 2024年第14期3卷 56-59页

作者：常明王莉杨兴振山东省泰安市肿瘤防治院呼吸一科山东泰安271000

目的研究抗结核药物引起儿童肝损伤(ATDILI)的危险因素。方法选取2021年1月至2022年12月在泰安市肿瘤防治院住院的确诊为结核病并行抗结核治疗的100例患儿为研究对象,根据药物不良反应相关指南确诊ATDILI的31例患儿为观察组,未发生ATDIL... 详细信息

目的研究抗结核药物引起儿童肝损伤(ATDILI)的危险因素。方法选取2021年1月至2022年12月在泰安市肿瘤防治院住院的确诊为结核病并行抗结核治疗的100例患儿为研究对象,根据药物不良反应相关指南确诊ATDILI的31例患儿为观察组,未发生ATDILI的69例患儿为对照组。采用logistic回归分析ATDILI的危险因素。结果两组年龄、治疗情况、合并肺外结核、贫血、低蛋白血症、营养不良比较,差异有统计学意义(P<0.05)。logistic回归分析结果显示,年龄、治疗情况、合并肺外结核、贫血、低蛋白血症、营养不良是ATDILI的独立危险因素(P<0.05)。结论年龄、治疗情况、合并肺外结核、贫血、低蛋白血症、营养不良是影响ATDILI的独立危险因素。

关键词：抗结核药物引起的肝损伤危险因素儿童

Maximum Cliques of Hypergraphs and Polynomial Optimization

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Acta Mathematicae Applicatae Sinica 2018年第4期34卷 842-855页

作者： Yan-ming chang Yue-jian PENG College of Mathematics Hunan University Changsha 410082 China Institute of Mathematics Hunan University Changsha 410082 China

A remarkable connection between the clique number and the Lagrangian of a graph was established by Motzkin and Straus. Later, Rota Bul′o and Pelillo extended the theorem of Motzkin-Straus to r-uniform hypergraphs by studying the relation of local（global） minimizers of a homogeneous polynomial function of degree r and the maximal（maximum） cliques of an r-uniform hypergraph. In this paper, we study polynomial optimization problems for non-uniform hypergraphs with four different types of edges and apply it to get an upper bound of Tur′an densities of complete non-uniform hypergraphs.

关键词： hypergraph maximum clique polynomial optimization

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广东区域通风廊道识别初探

热带气象学报 2024年第3期40卷 445-455页

作者：杨土士王伟文常鸣王雪梅中国气象局广州热带海洋气象研究所广东广州510641 暨南大学环境与气候研究院广东广州511443 粤港澳环境质量协同创新联合实验室广东广州511443

以广东省为例,通过绘制空气动力学粗糙长度,从动力学角度初步识别出通风潜力;利用数值模拟输出的冬夏季平均水平风场,结合近地面温度和粗糙长度加权后得到通风指数,发现城际尺度风道分布受季节热力差异影响,冬季通风能力显著优于夏季。... 详细信息

以广东省为例,通过绘制空气动力学粗糙长度,从动力学角度初步识别出通风潜力;利用数值模拟输出的冬夏季平均水平风场,结合近地面温度和粗糙长度加权后得到通风指数,发现城际尺度风道分布受季节热力差异影响,冬季通风能力显著优于夏季。将通风评价结果划分为4个等级,从广东全域尺度分冬、夏两季识别了潜在风道。

关键词：通风廊道城市化地表粗糙度城市热岛数值模拟土地利用土地覆盖

黄河流域红色旅游空间分布格局及发展水平评价研究

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延安大学学报（社会科学版） 2024年第3期46卷 73-79页

作者：白鹏飞常冀明延安大学经济与管理学院陕西延安716000

黄河流域拥有丰富的红色旅游资源,发展红色旅游是沿线省市经济增长的有效途径。为评价黄河流域红色旅游空间分布格局及发展水平,运用空间统计方法,分析黄河流域九省红色旅游空间格局和核密度估计,并通过筛选红色旅游城市,对黄河流域红... 详细信息

黄河流域拥有丰富的红色旅游资源,发展红色旅游是沿线省市经济增长的有效途径。为评价黄河流域红色旅游空间分布格局及发展水平,运用空间统计方法,分析黄河流域九省红色旅游空间格局和核密度估计,并通过筛选红色旅游城市,对黄河流域红色旅游发展水平进行测度。研究认为,黄河流域红色旅游空间分布不均衡、发展不均衡且发展差异呈扩大趋势,沿线省市应从深挖红色旅游价值内涵、创新红色旅游发展模式和推进红色旅游区域协同三个方面发展红色旅游产业。

关键词：黄河流域红色旅游空间分布

Spatial distribution analysis of landslides triggered by the 2013-04-20 Lushan earthquake,China

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Earthquake Engineering and Engineering Vibration 2016年第1期15卷 163-171页

作者： chang ming Tang Chuan Xia Chenhao Fang Qunsheng State Key Laboratory of Geo-hazard Prevention and Geo-environment Protection Chengdu University of Technology

The 2013-04-20 Lushan earthquake（seismic magnitude Ms 7.0 according to the State Seismological Bureau）induced a large number of *** this study,spatial characteristics of landslides are developed by interpreting digital aerial photography *** towns near the epicenter,with an area of about 11.11 km2,were severely affected by the earthquake,and 703 landslides were identified from April 24,2013 aerial photography data over an area of 1.185 *** 55.56% of the landslide area was less than 1000 m2,whereas about 3.23 % was more than 10,000 *** falls and shallow landslides were the most commonly observed types in the study area,and were primarily located in the center of Lushan *** landslide areas were widely distributed near river channels and along *** main factors were chosen to study the distribution characteristics of landslides：elevation,slope gradients,fault,geologic unit and river *** spatial distribution of coseismal landslides is studied statistically using both landslide point density（LPD）,defined as the number of landslides（LS Number）per square kilometer,and landslide area density（LAD）,interpreted as the percentage of landslides area affected by *** results show that both LPD and LAD have strong positive correlations with five main *** landslides occurred in the gradient range of 40°-50° and an elevation range of 1.0-1.5 km above sea *** results also indicate that landslides were mainly formed in soft rocks such as mudstone and sandstone,and concentrated in IX intensity areas.

关键词： Lushan earthquake landslide spatial distribution impact factor

Elevating kinetics of passivated Fe anodes with NH_(4)Cl regulator:Toward low-cost,long-cyclic and green cathode-free Fe-ion aqueous batteries

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Nano Research 2022年第4期15卷 3187-3194页

作者： Shibo Chai Jianhui Zhu Jian Jiang chang ming Li School of Physical Science and Technology Southwest UniversityNo.2 Tiansheng RoadBeiBei DistrictChongqing 400715China School of Materials and Energy and Chongqing Key Lab for Advanced Materials and Clean Energies of TechnologiesSouthwest UniversityNo.2 Tiansheng RoadBeiBei DistrictChongqing 400715China Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province Key Laboratory of Functional Materials and Photoelectrochemistry of HaikouCollege of Chemistry and Chemical EngineeringHainan Normal UniversityHaikou 571158China

The environment benignity and battery cost are major concerns for grid-scale energy storage *** emerging dendrite-free Fe-ion aqueous batteries are promising due to the rich natural abundance,low cost and non-toxicity for Fe ***,serious passivation reactions on Fe anodes and poor long-term cyclability for matched cathodes still stand in the way for their practical *** settle above constraints,we herein use NH_(4)Cl as the electrolyte regulator to elevate the reaction kinetics of passivated Fe anodes,and also propose a special cathode-free design to prolong the cells lifetime over 1,000 *** added NH_(4)Cl can erode/break inert passivation layers and strengthen the ion conductivity of electrolytes,facilitating the reversible Fe plating/stripping and Fe^(2+)*** highly puffed nano carbon foams function as current collectors and actives anchoring hosts,enabling expedite Fe^(2+)adsorption/desorption,FeII/FeIII redox conversions and FeIII *** configured rocking-chair Fe-ion cells have good environmental benignity and decent energy-storage behaviors,including high reactivity/reversibility,outstanding cyclic stability and far enhanced operation *** economical,long-cyclic and green cathode-free Fe-ion batteries may hold great potential in near-future energy-storage power stations.

关键词： elevated kinetics passivated Fe anodes NH_(4)Cl regulator cathode-free design Fe-ion batteries

基于多质点模型的输电塔线体系随机风振响应研究

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武汉理工大学学报 2024年第6期46卷 35-39页

作者：陈波李昂昌明静武汉理工大学土木工程与建筑学院武汉430070

输电塔线体系在风致振动表现出强烈的非线性特征,因此不能直接采用现有的结构随机风振响应分析方法。基于此,开展了输电塔线体系的随机风振响应研究。采用Hamilton原理建立了输电塔线体系的势能和动能表达式,通过等价线性化方法建立了... 详细信息

输电塔线体系在风致振动表现出强烈的非线性特征,因此不能直接采用现有的结构随机风振响应分析方法。基于此,开展了输电塔线体系的随机风振响应研究。采用Hamilton原理建立了输电塔线体系的势能和动能表达式,通过等价线性化方法建立了塔线体系随机风振反应的分析模型。以某实际大跨越输电塔线体系为实际工程背景开展了其随机风振响应分析。结果表明,从频域角度可以有效地分析评估输电塔线体系的风振响应特点和规律。

关键词：输电线路风荷载随机振动谱密度

Mechanisms of water oxidation on heterogeneous catalyst surfaces

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Nano Research 2021年第10期14卷 3446-3457页

作者： Xiaogang Yang Yuanxing Wang chang ming Li Dunwei Wang Institute of Materials Science and Devices School of Materials Science and EngineeringSuzhou University of Science and TechnologySuzhou 215011China Department of Chemistry Boston CollegeMerkert Chemistry CenterMA 02467USA Institute of Clean Energy&Advanced Materials Southwest UniversityChongqing 400715China

Water oxidation,an essential step in photosynthesis,has attracted intense research *** the reaction pathways at the electrocatalyst/water interface is of great importance for the development of water oxidation *** the water is oxidized on the electrocatalyst surface by the positive charges is still an open *** review summarizes current advances in studies on surface chemistry within the context of water oxidation,including the intermediates,reaction mechanisms,and their influences on the reaction *** Tafel analyses of some electrocatalysts and the rate-laws relative to charge consumption rates are also ***,how the multiple charge transfer relies on the intermediate coverage and the accumulated charge numbers is ***,the intermediates and rate-determining steps on some water oxidation catalysts are discussed based on density functional theories.

关键词： water oxidation intermediate rate-determining step rate-law Tafel analysis density functional theory

Homemade lyophilized cross linking amniotic sustained-release drug membrane with anti-scarring role after filtering surgery in rabbit eyes

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International Journal of Ophthalmology(English edition) 2012年第5期5卷 555-561页

作者： Wan Li, ming-chang Zhang Department of Ophthalmology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei Province China Department of Orthopedics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Department of Ophthalmology Central Hospital of Yichang Yichang 443000 Hubei Province China

AIM: To investigate the antifibrotic effect of the freeze-dried bilayered fibrin-binding amniotic membrane as a drug delivery system on glaucoma surgery in rabbit model. The aim of this study was to prepare a novel local delivery system for the sustained and controllable release of 5-Fu. METHODS: Twenty-four Japanese white rabbits were randomized into three groups: the experimental group (ocular trabeculectomy in combination with 5-Fu loaded freeze-dried bilayered fibrin-binding amniotic membrane transplantation), the control group (ocular trabeculectomy in combination with 5-Fu) and the blank group (single trabeculectomy). HE staining, massion staining and immunohistochemistry for alpha -SMA were performed on days 7, 14, 21 and 30 following surgery. The concentration of 5-Fu in rabbit aqueous humor was examined by high performance liquid chromatography (HPLC) 3 days after the surgery. RESULTS: Statistical differences were noted in intraocular pressure among groups on day 7, 14, 21 and 30 following surgery. Histology further demonstrated that trabeculectomy in combination with freeze-dried bilayered fibrin-binding amniotic membrane yielded well wound healing and no scar formation and was beneficial for long term effect. CONCLUSION: HPLC showed a good slow-release effect with freeze-dried bilayered fibrin-binding amniotic membrane.

关键词： freeze-dried bilayered fibrin-binding amniotic membrane drug delivery system filtering surgery glaucoma inhibition of scarring formation