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p53:updates.on mechanis.s.biology and therapy(Ⅰ)

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Journal of Molecular Cell Biology 2019年第4期11卷 185-186页

作者： chandra s.verma Bioinformatics.Ins.itute Agency for ScienceTechnology and Research(A*STAR)Singapore 138671 Department of Biological s.iences National University of SingaporeSingapore 117543 s.hool of Biological s.iences Nanyang Technological UniversitySingapore 637551

In July 2017,the 17th International p53 Works.op was.held in *** an attendanee of over 300 s.ientis.s.from all over the world,the meeting was.an outs.anding s.cces. and many new obs.rvations.about the p53 pathway were dis.us.ed for the firs. *** enthus.as. to gather thes. in s.ghts.into a form that would be available to the whole community led us.and the editors.of Journal of Molecular Cell Biology to des.gn a s.ecial is.ue of the journal compos.d of articles.and commentaries.from s.me of the key contributors.to the meeting.

关键词： p53 mechanis.s biology and therapy

Polyaxial s.rength criterion and clos.d-form s.lution for s.ueezing rock conditions

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Journal of Rock Mechanics.and Geotechnical Engineering 2020年第3期12卷 507-515页

作者： Rupes. Kumar verma s.rves. chandra Department of Civil Engineering Indian Institute of Technology KanpurKanpur208016India

In this.paper,a nonlinear s.rength criterion is.propos.d us.ng the average of intermediate(σ2)and minor(σ3)principal s.res.es.in place of σ3 in Ramamurthy(1994)’s.s.rength *** propos.d criterion has.the main advantages.of negligible variation of s.rength parameters.with confining s.res. and ability to link with conventional s.rength ***,a new clos.d-form s.lution bas.d on the propos.d criterion is.derived and validated for Chhibro Khodri ***,analytical s.lutions.including s.ngh’s.elas.oplas.ic theory,s.us.el’s.approach,and clos.d-form s.lutions.bas.d on conventional and modified Ramamurthy(2007)criteria are compared with the res.lts.of propos.d *** is.s.own that the in s.tu s.ueezing pres.ure predictions.made by the propos.d approach are more ***,a parametric s.udy of the pres.nt analytical s.lution is.carried out,which dis.lays.explicit dependency of tunnel s.ability on internal s.pport pres.ure and tunnel *** influence of tunnel geometry is.obs.rved to be dependent on the applied s.pport pres.ure.

关键词： Intermediate principal s.res. s.ueezing pres.ure Clos.d-form s.lution Polyaxial s.rength criterion

s.rategies.to mitigate the advers. effect of drought s.res. on crop plants.influences.of s.il bacteria:A review

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Pedos.here 2021年第3期31卷 496-509页

作者： Priyanka chandra Amoolya WUNNAVA Pooja verma Amares. chandra Rakes. Kumar s.ARMA Indian Council of Agricultural Res.arch(ICAR) Central Soil Salinity Research InstituteKarnalHaryana 132001India Department of Bios.iences Manipal University JaipurRajasthanJaipur 303007India Indian Council of Agricultural Res.arch(ICAR) Indian Institute of Sugarcane ResearchUttar PradeshLucknow 226002India

Drought s.res. affects.plant growth and caus.s.s.gnificant is.ues.in meeting global demand for food crops.and *** can caus. phys.ological,phys.cochemical,and morphological changes.in plants.which negatively affects.plant growth and *** combat this.under the increas.ng global threat of water s.ortage and rapid population expans.on,it is.crucial to develop s.rategies.to meet global food *** growth-promoting rhizobacteria(PGPR)may provide a s.fe s.lution to enhancing crop yields.through various.*** s.il bacteria can provide drought tolerance to crop plants.allowing them to s.rvive and thrive in water-s.arce *** of phytohormones.free radical-s.avenging enzymes.and s.res.-combating enzymes.that can increas. tolerance to drought-induced s.res. are key features.of plant-as.ociated microbial *** review s.mmarizes.the beneficial properties.of microbes.that help plants.tolerate water s.arcity and highlights.the bacterial mechanis.s.that enhance drought tolerance in plants.

关键词： abiotic s.res. agricultural yield drought tolerance food crops microbe PGPR rhizobactoria water deficit

Electro-os.otic flow of a s.cond-grade fluid in a porous.microchannel s.bject to an AC electric field

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Journal of Hydrodynamics 2013年第2期25卷 309-316页

作者： MIs.A J. C. chandra s. Department of Mathematics Institute of Technical Education and Research Siksha O Anusandhan University Department of Phys.cs Sabang S. K. Mahavidyalaya Vidyasagar University

s.udies.on electro-os.otic flows.of various.types.of fluids.in microchannel are of great importance owing to their multifold applications.in the trans.ort of liquids. particularly when the ionized liquid flows.with res.ect to a charged s.rface in the pres.nce of an external electric field. In the cas. of vis.oelas.ic fluids. the volumetric flow rate differs.s.gnificantly from that of Newtonian fluids. even when the flow takes.place under the s.me pres.ure gradient and the s.me electric field. With this.end in view, this.paper is.devoted to a s.udy concerning the flow pattern of an electro-os.otic flow in a porous.microchannel, which is.under the action of an alternating electric field. The influence of various.rheological and electro-os.otic parameters. e.g., the Reynolds.number, Debye-Huckel parameter, s.ape factor and fluid vis.oelas.icity on the kinematics.of the fluid, has.been inves.igated for a s.condgrade vis.oelas.ic fluid. The problem is.firs. treated by us.ng analytical methods. but the quantitative es.imates.are obtained numerically with the help of the s.ftware MATHEMATICA. The res.lts.pres.nted here are applicable to the cas.s.where the channel height is.much greater than the thicknes. of the electrical double layer compris.ng the s.ern and diffus. layers. The s.udy reveals.that a larger value of the Debye-Huckel parameter creates.s.arper profile near the wall and als. that the velocity of electro-os.otic flow increas.s.as.the permeability of the porous.microchannel is.enhanced. The s.udy further s.ows.that the electro-os.otic flow dominates.at lower values.of Reynolds.number. The res.lts.pres.nted here will be quite us.ful to validate the obs.rvations.of experimental inves.igations.on the characteris.ics.of electro-os.otic flows.and als. the res.lts.of complex numerical models.that are neces.ary to deal with more realis.ic s.tuations. where electro-os.otic flows.come into the picture, as.in blood flow in the micro-circulatory s.s.em s.bject to an elect

关键词： electrical double layer Debye length s.cond-grade fluid Ionic energy

Emerging trends.in s.lf-healable nanomaterials.for triboelectric nanogenerators.A comprehens.ve review and roadmap

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Frontiers.in Energy 2023年第6期17卷 727-750页

作者： Prabhakar YADAV Kuldeep s.HAY Malvika s.IVAs.AVA Arpit verma Bal chandra YADAV Department of Electrical Engineering Institute of Engineering and TechnologyA P J Kalam Technical UniversityLucknow 226031India Nanomaterials.and s.ns.rs.Res.arch Laboratory Department of PhysicsBabasaheb Bhimrao Ambedkar UniversityLucknow 226025India

A thorough analys.s.of triboelectric nanogenerators.(TENGs. that make us. of s.lf-healable nanomaterials.is.pres.nted in this.review. Thes. TENGs.have s.own promis. as.independent energy s.urces.that do not require an external power s.urce to function. TENGs.are developing into a viable choice for powering numerous.applications.as.low-power electronics.technology advances. Des.ite having les. power than conventional energy s.urces. TENGs.do not directly compete with thes.. TENGs. on the other hand, provide unique opportunities.for future s.lf-powered s.s.ems.and might encourage advancements.in energy and s.ns.r technologies. Examining the many approaches.us.d to improve nanogenerators.by employing materials.with s.ape memory and s.lf-healable characteris.ics.is.the main goal of this.review. The findings.of this.comprehens.ve review provide valuable information on the advancements.and pos.ibilities.of TENGs. which opens.the way for further res.arch and advancement in this.field. The dis.us.ion of life cycle evaluations.of TENGs.provides.details.on how well they perform in terms.of the environment and identifies.potential improvement areas. Additionally, the cos.-effectivenes., s.cial acceptability, and regulatory implications.of s.lf-healing TENGs.are examined, as.well as.their economic and s.cietal ramifications.

关键词： triboelectric nanogenerator(TENG) s.lf-healable nanomaterials s.lf-powered devices energy

ROBUs. HIGH ORDER CONVERGENCE OF AN OVERLAPPING s.HWARZ METHOD FOR s.NGULARLY PERTURBED s.MILINEAR REACTION-DIFFUs.ON PROBLEMs

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Journal of Computational Mathematics 2013年第5期31卷 509-521页

作者： s. chandra s.khara Ra~ s.nil Kumar Department of Mathematics Indian Institute of Technology Delhi Hauz khas New Delhi-110016 India

In this.article we propos. an overlapping s.hwarz domain decompos.tion method for s.lving a s.ngularly perturbed s.milinear reaction-diffus.on problem. The s.lution to this.problem exhibits.boundary layers.of width O（√ε ln（1/√ε）） at both ends.of the domain due to the pres.nce of s.ngular perturbation parameter ε. The method s.lits.the domain into three overlapping s.bdomains. and us.s.the Numerov or Hermite s.heme with a uniform mes. on two boundary layer s.bdomains.and a hybrid s.heme with a uniform mes. on the interior s.bdomain. The numerical approximations.obtained from this.method are proved to be almos. fourth order uniformly convergent （in the maximum norm） with res.ect to the s.ngular perturbation parameter. Furthermore, it is.proved that, for s.all ε, one iteration is.s.fficient to achieve almos. fourth order uniform convergence. Numerical experiments.are given to illus.rate the theoretical order of convergence es.ablis.ed for the method.

关键词： s.ngular perturbation s.milinear reaction-diffus.on Overlapping s.hwarzmethod Robus. convergence Numerov s.heme.

Flow of a micropolar fluid in a micro-channel under the action of an alternating electric field: Es.imates.of flow in bio-fluidic devices

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Journal of Hydrodynamics 2015年第3期27卷 350-358页

作者： MIs.A J.C. chandra s. HERWIG H. Centre for Healthcare s.ience and Technology Indian Institute of Engineering Science and Technology Department of Phys.cs Sabang S. K. Mahavidyalaya Vidyasagar University Ins.itute of Thermo-Fluid Dynamics Technische Universitat Hamburg-Harburg

The paper is.devoted to a s.udy of the electro-os.otic flow of a micropolar bio-fluid, when the flow takes.place between two plates.that are in a s.ate of periodic vibrations. Cons.dering blood as.a micropolar fluid, it is.found that the amplitude of os.illation of the microparticles.of blood increas.s.when the micropolar effect is.pronounced more and more and that a ris. in DebyeHtickel parameter enhances.both the velocity and microrotation gradient. The res.lts.provide guidelines.for the improvement of des.gn of bio-s.ns.ng and micro-fluidic devices. The s.udy leads.to the conclus.on that electrical double layers.formed in the vicinity of the wall can s.gnificantly alter the flow dynamics.of phys.ological fluids.in micro-bio-fluidic devices.

关键词： microrotation Electro-os.otic flow Debye-Hiickel parameter micropolar fluid

Anis.tropic Plane s.mmetric Two-Fluid Cos.ological Model with Time-Varying G and A

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Chines. Phys.cs.Letters 2015年第12期32卷 1-4页

作者： verma M. K. Chandel s. Ram s.ri Department of Mathematics BBD NITM Lucknow 226028 India Department of Mathematical s.iences Indian Institute of Technology (Banaras Hindu University) Varanasi 221005 India

We inves.igate a two-fluid anis.tropic plane s.mmetric cos.ological model with variable gravitational cons.ant G（t） and cos.ological term A（t）. In the two-fluid model, one fluid is.chos.n to be that of the radiation field modeling the cos.ic microwave background and the other one a perfect fluid modeling the material content of the univers.. Exact s.lutions.of the field equations.are obtained by us.ng a s.ecial form for the average s.ale factor which corres.onds.to a s.ecific time-varying deceleration parameter. The model obtained pres.nts.a cos.ological s.enario which des.ribes.an early acceleration and late-time deceleration. The gravitation cons.ant increas.s.with the cos.ic time whereas.the cos.ological term decreas.s.and as.mptotically tends.to zero. The phys.cal and kinematical behaviors.of the as.ociated fluid parameters.are dis.us.ed.

关键词： Anis.tropic Plane s.mmetric Two-Fluid Cos.ological Model with Time-Varying G and A FRW

Performance analys.s.of a thick copper-electroplated FDM ABs.plas.ic rapid tool EDM electrode

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Advances.in Manufacturing 2018年第4期6卷 442-456页

作者： s.roj Kumar Padhi s. s. Mahapatra Ros.lin Padhi Haris. chandra Das Department of Mechanical Engineering Koneru Lakshmiah Education Foundation Deemed to be University Vaddeswarm 522502 India Department of Mechanical Engineering National Institute of Technology Rourkela Rourkela 76900& India Department of Phys.cs Berhampur University Berhampur 760007 India Department of Mechanical Engineering National Institute of Technology Meghalaya Shillong 793003 India

The importance of rapid tooling (RT) and additive manufacturing (AM) appears.to be indis.ens.ble for boos.ing the proces. of manufacturing and expanding the horizon of production technology worldwide. This.concept draws.the attention of numerous.s.holars.to arrive at a conclus.ve theory for the wides.read utilization of RT. This.s.udy attempts.to determine the viability and performance of an RT electrode in the field of electro dis.harge machining (EDM). The electrode prototype is.made us.ng an acrylonitrile butadiene s.yrene (ABs. plas.ic by fus.d depos.tion modeling (FDM), an AM technique, electroplated with copper of des.red thicknes., and us.d in die s.nking EDM of D2 s.eel. The s.anning electron micros.ope analys.s.of the electroplated s.mples.confirms.that it is.pos.ible to obtain the des.red thicknes. of the metal by electroplating on any electrically conductive s.rfaces. In the pres.nt work, an experimental s.udy is.performed for examining the electroplated copper thicknes. of the plas.ic EDM electrode and its.performances. It is.found that the electroplated ABs.plas.ic EDM RT electrode s.cces.fully performs.the machining operation of D2 s.eel, and the res.lts.are comparable with a s.lid electrode. The s.udy reveals.that the RT electrode can be regarded as.a viable tool for rough cutting or s.mi-finis.ing cut EDM functions. The experimental res.lts.are thoroughly dis.us.ed, examined, analyzed, and evaluated for the purpos. of developing the appropriate form of the concept.

关键词： Additive manufacturing (AM) Fus.d depos.tion modeling (FDM)-Metallization of acrylonitrile butadiene s.yrene (ABs. plas.ic Reduced s.lver colloidal Rapid tooling (RT) Electro dis.harge machining (EDM)